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Article: Is nodal disease burden relevant in patients with renal cell carcinoma and lymph node invasion?

2019 Volume 7, Issue Suppl 3, Page(s) S149

Language	English
Publishing date	2019-09-25
Publishing country	China
Document type	Editorial ; Comment
ZDB-ID	2893931-1
ISSN	2305-5847 ; 2305-5839
ISSN (online)	2305-5847
ISSN	2305-5839
DOI	10.21037/atm.2019.06.31
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Article ; Online: Summary and considerations in genitourinary cancer patient care during the COVID-19 Pandemic.

Rodríguez-Covarrubias, Francisco / Castillejos-Molina, Ricardo A / Autrán-Gómez, Ana María

International braz j urol : official journal of the Brazilian Society of Urology

2020 Volume 46, Issue suppl.1, Page(s) 98–103

Abstract: Purpose: To provide a summary and recommendations for the set-up of strategies for cancer patients care in genitourinary oncology clinics during the pandemic and in the recovery period.: Material and methods: A non-systematic review of available ... ...

Abstract	Purpose: To provide a summary and recommendations for the set-up of strategies for cancer patients care in genitourinary oncology clinics during the pandemic and in the recovery period. Material and methods: A non-systematic review of available literature on the management of urological malignancies during the COVID-19 pandemic was performed to summarize recommendations to improve the diagnosis and treatment of urological cancers during and after the contingence, including clinical and research aspects. Results: Urological cancer diagnosis and management should be tailored according to the severity of the COVID-19 crisis in each region and the aggressiveness of each tumor. Clinicians should adhere to strict protocols in order to prioritize the attention of patients with high-risk malignancies while optimizing resources to avoid the saturation of critical care services. Conclusions: During the COVID-19 pandemic urological cancer care has been severely impaired. For proper patient management, multidisciplinary approach is encouraged tailoring therapy according to COVID-19 regional behavior and local institutional resources. Patients with high-risk malignancies should be prioritized.
MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Humans ; Medical Oncology/methods ; Pandemics ; Patient Care ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Urogenital Neoplasms/therapy
Keywords	covid19
Language	English
Publishing date	2020-06-12
Publishing country	Brazil
Document type	Journal Article ; Review
ZDB-ID	2206649-4
ISSN	1677-6119 ; 1677-5538
ISSN (online)	1677-6119
ISSN	1677-5538
DOI	10.1590/S1677-5538.IBJU.2020.S115
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Article ; Online: Editorial comment.

Rodriguez-Covarrubias, Francisco

The Journal of urology

2013 Volume 190, Issue 6, Page(s) 2073

MeSH term(s)	Adenocarcinoma/pathology ; Adenocarcinoma/surgery ; Humans ; Male ; Prostatectomy ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms/surgery
Language	English
Publishing date	2013-12
Publishing country	United States
Document type	Comment ; Editorial
ZDB-ID	3176-8
ISSN	1527-3792 ; 0022-5347
ISSN (online)	1527-3792
ISSN	0022-5347
DOI	10.1016/j.juro.2013.05.127
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Ui VI Zs.91: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
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Article ; Online: [No title information]

Torres-Sánchez, Luisa Elvira / Hernández-Pérez, Jesús Gibran / Escamilla-Nuñez, Consuelo / Rodríguez-Covarrubias, Francisco / Manzanilla-García, Hugo / Mohar, Alejandro / Morales-Carmona, Evangelina / Espin-Arellano, Lucino Iván / Hernández-Ávila, Juan Eugenio / Lajous, Martin

Salud publica de Mexico

2023 Volume 65, Issue 3, may-jun, Page(s) 236–244

Abstract: Objective: To estimate prostate cancer (PC) survival in Mexico and explore survival disparities according to the marginalization level of residence place.: Materials and methods: A nationwide administrative claims database (4 110 men) whose PC ... ...

Title translation	Disparities on prostate cancer survival in Mexico: a retrospective cohort study.
Abstract	Objective: To estimate prostate cancer (PC) survival in Mexico and explore survival disparities according to the marginalization level of residence place. Materials and methods: A nationwide administrative claims database (4 110 men) whose PC treatment was financed by Seguro Popular between 2012-2016, was cross-linked to the National Mortality Registry up to December 2019. Patients were classified according to their oncological risk at diagnosis and the marginalization level of the residence municipality. Cox proportional hazards regression was used to estimate multivariable survival functions. Results: Five-years PC survival (69%; 95%CI: 68,71%) ranged from 72% to 54% at very low and very high marginalization, respectively (p for trend<0.001). The lowest PC survival was observed in men with high-risk PC (47%; 95%CI: 33,66%) residents in very high marginalization municipalities. Conclusions: Overall, PC survival was lower than that reported in other Latin American countries. The distribution of oncologic risk and survival differences across marginalization levels suggests limited early detection and cancer health disparities.
Language	Spanish
Publishing date	2023-04-21
Publishing country	Mexico
Document type	English Abstract ; Journal Article
ZDB-ID	954220-6
ISSN	1606-7916 ; 0036-3634
ISSN (online)	1606-7916
ISSN	0036-3634
DOI	10.21149/14266
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Article: Transitioning from conformal radiotherapy to intensity-modulated radiotherapy after radical prostatectomy: Clinical benefit, oncologic outcomes and incidence of gastrointestinal and urinary toxicities.

Flores-Balcázar, C H / Urías-Arce, D M / Bourlon, M T / Gabilondo-Navarro, F / Pérez-Álvarez, S I / Ramos-Prudencio, R / Rodríguez-Covarrubias, F

Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology

2020 Volume 25, Issue 4, Page(s) 568–573

Abstract: Aim: The purpose of this study was to review genitourinary (GU) and gastrointestinal (GI) toxicity associated with high-dose radiotherapy (RT) delivered with 3-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy (IMRT) or ... ...

Abstract	Aim: The purpose of this study was to review genitourinary (GU) and gastrointestinal (GI) toxicity associated with high-dose radiotherapy (RT) delivered with 3-dimensional conformal radiotherapy (3D-CRT) and intensity-modulated radiotherapy (IMRT) or volumetric arc therapy (VMAT) following radical prostatectomy (RP). Background: RP is a therapeutic option for the management of prostate cancer (PrCa). When assessing postoperative RT techniques for PrCa, the published literature focuses on patients treated with 2-dimensional conventional methods without reflecting the implementation of 3D-CRT, IMRT, or VMAT. Materials and methods: A total of 83 patients were included in this analysis; 30 patients received 3D-CRT, and 53 patients received IMRT/VMAT. Acute and late symptoms of the GU and lower GI tract were retrospectively graded according to the Radiation Therapy Oncology Group and the European Organization for Research and Treatment of Cancer radiation toxicity grading systems. The relapse failure-free rate and overall survival were also evaluated. Results: The rate of acute GU toxicity was 9.4% vs. 13.3% for the IMRT/VMAT and 3D-CRT groups (p = 0.583). The 5-year actuarial rates of late GI toxicity for IMRT/VMAT and 3D-CRT treatments were 1.9% and 6.7%, respectively. The rate of late GU toxicity for the IMRT/VMAT and 3D-CRT treatment groups was 7.5% and 16.6%, respectively (p = 0.199). We found no association between acute or late toxicity and the RT technique in univariate and multivariate analyses. Conclusion: Postprostatectomy IMRT/VMAT and 3D-CRT achieved similar morbidity and cancer control outcomes. The clinical benefit of highly conformal techniques in this setting is unclear although formal analysis is needed.
Language	English
Publishing date	2020-05-21
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2188087-6
ISSN	1507-1367
ISSN	1507-1367
DOI	10.1016/j.rpor.2020.04.018
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Article ; Online: Risk factors for the development of postoperative complications in patients with metastatic kidney cancer treated with cytoreductive nephrectomy.

Hernández-Pañeda, Humberto / Garza-Gangemi, Adrián M / Manzanilla-Romero, Héctor H / Hernández-Gaytán, Cristian A / Gabilondo-Navarro, Fernando / Rodríguez-Covarrubias, Francisco

Cirugia y cirujanos

2021 Volume 89, Issue 5, Page(s) 632–637

Abstract: Background: The role of cytoreductive nephrectomy on the treatment of metastatic renal cell carcinoma (mRCC) is controversial due to its high complexity.: Objective: To identify risk factors associated to postoperative complications in patients with ... ...

Title translation	Factores de riesgo para el desarrollo de complicaciones posquirúrgicas en pacientes con cáncer renal metastásico tratados con nefrectomía citorreductora.
Abstract	Background: The role of cytoreductive nephrectomy on the treatment of metastatic renal cell carcinoma (mRCC) is controversial due to its high complexity. Objective: To identify risk factors associated to postoperative complications in patients with mRCC after cytoreductive nephrectomy. Method: We conducted a retrospective, observational study in 67 patients who underwent cytoreductive nephrectomy for the management of mRCC. Demographic, perioperative and clinicopathologic -characteristics were registered. Surgical complications were classified using the Clavien-Dindo system; major complications were those of grade 3 or higher. We performed a binary logistic regression analysis to identify risk factors associated with surgical complications. Results: Mean age was 56 years (37-83). Symptoms were present in 58 patients (89.7%). Weight loss was the predominant symptom (50.8%). Mean tumor diameter was 10.8 cm (4.6-22.5 cm). The rate of postoperative complications was 65%; 21 patients (31.4%) had major complications. Risk factors were estimated blood loss > 500 ml (OR 44.5, CI 95% 2.51-789, p = 0.01) and tumor diameter > 10 cm (OR 17.9, CI 95% 1.2-273, p = 0.04). Conclusions: Cytoreductive nephrectomy is a good option in highly selected patients with mRCC. Our major complication rate was 31.4%. Risk factors associated were blood loss and tumor diameter.
MeSH term(s)	Carcinoma, Renal Cell/surgery ; Cytoreduction Surgical Procedures/adverse effects ; Humans ; Kidney Neoplasms/surgery ; Middle Aged ; Nephrectomy/adverse effects ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Retrospective Studies ; Risk Factors
Language	English
Publishing date	2021-10-19
Publishing country	Mexico
Document type	Journal Article ; Observational Study
ZDB-ID	730699-4
ISSN	2444-054X ; 0009-7411
ISSN (online)	2444-054X
ISSN	0009-7411
DOI	10.24875/CIRU.20000871
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Article: Summary and considerations in genitourinary cancer patient care during the COVID-19 Pandemic

Rodríguez-Covarrubias, Francisco / Castillejos-Molina, Ricardo A. / Autrán-Gómez, Ana María

International braz j urol : official journal of the Brazilian Society of Urology

Abstract: PURPOSE: To provide a summary and recommendations for the set-up of strategies for cancer patients care in genitourinary oncology clinics during the pandemic and in the recovery period MATERIAL AND METHODS: A non-systematic review of available literature ...

Abstract	PURPOSE: To provide a summary and recommendations for the set-up of strategies for cancer patients care in genitourinary oncology clinics during the pandemic and in the recovery period MATERIAL AND METHODS: A non-systematic review of available literature on the management of urological malignancies during the COVID-19 pandemic was performed to summarize recommendations to improve the diagnosis and treatment of urological cancers during and after the contingence, including clinical and research aspects RESULTS: Urological cancer diagnosis and management should be tailored according to the severity of the COVID-19 crisis in each region and the aggressiveness of each tumor Clinicians should adhere to strict protocols in order to prioritize the attention of patients with high-risk malignancies while optimizing resources to avoid the saturation of critical care services CONCLUSIONS: During the COVID-19 pandemic urological cancer care has been severely impaired For proper patient management, multidisciplinary approach is encouraged tailoring therapy according to COVID-19 regional behavior and local institutional resources Patients with high-risk malignancies should be prioritized
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #600943
Database	COVID19

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Article ; Online: Association between life-course leisure-time physical activity and prostate cancer.

Vázquez-Salas, Ruth Argelia / Torres-Sánchez, Luisa / Galván-Portillo, Marcia / López-Carrillo, Lizbeth / Moreno-Macías, Hortensia / Rodríguez-Covarrubias, Francisco / Romero-Martínez, Martín / Jiménez-Ríos, Miguel Ángel

Salud publica de Mexico

2022 Volume 64, Issue 2, Page(s) 169–178

Abstract: Objective: To evaluate the association between life-course leisure-time physical activity (PA) and prostate cancer (PC) among males living in Mexico City. Materials and meth-ods. Information from 394 incident PC cases and 794 popula-tion controls ... ...

Abstract	Objective: To evaluate the association between life-course leisure-time physical activity (PA) and prostate cancer (PC) among males living in Mexico City. Materials and meth-ods. Information from 394 incident PC cases and 794 popula-tion controls matched by age (± 5 years), was analyzed. Using leisure-time PA information at different life stages, life-course PA patterns were constructed. The association between PA and PC was estimated using an unconditional logistic regres-sion model. Results: Three life-course PA patterns were identified: low PA (71.0%), moderate PA (22.0%), and high PA (7.0%); this last pattern was characterized by higher levels and consistent PA practice. Compared with inactive males, those in the high PA pattern (OR: 0.50; 95%CI: 0.26-0.93) had significantly lower PC odds. Conclusion: Intense and regular PA could reduce the possibility of PC. These results are in accordance with PA World Health Organization rec-ommendations.
MeSH term(s)	Exercise ; Humans ; Leisure Activities ; Logistic Models ; Male ; Prostatic Neoplasms/epidemiology ; Sedentary Behavior
Language	English
Publishing date	2022-04-08
Publishing country	Mexico
Document type	Journal Article
ZDB-ID	954220-6
ISSN	1606-7916 ; 0036-3634
ISSN (online)	1606-7916
ISSN	0036-3634
DOI	10.21149/12540
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Article ; Online: Metabolic Syndrome and Prostate Cancer Risk: A Population Case-control Study.

Hernández-Pérez, Jesús Gibran / Torres-Sánchez, Luisa / Hernández-Alcaráz, César / López-Carrillo, Lizbeth / Rodríguez-Covarrubias, Francisco / Vázquez-Salas, Ruth Argelia / Galván-Portillo, Marcia

Archives of medical research

2022 Volume 53, Issue 6, Page(s) 594–602

Abstract: Background: Metabolic syndrome (MS) with mixed dyslipidemia and prostate cancer (PC) are relevant health problems among Mexican men. However, there is no information regarding the association between MS and PC for this population.: Aim of the study: ... ...

Abstract	Background: Metabolic syndrome (MS) with mixed dyslipidemia and prostate cancer (PC) are relevant health problems among Mexican men. However, there is no information regarding the association between MS and PC for this population. Aim of the study: To evaluate this association in a population case-control study in Mexico City. Methods: We analyzed the information from 394 incident PC-cases and 793 population age-matched (± 5 years) controls, identified in Mexico City (2011-2014). For cases, Gleason score at diagnosis was available. We defined MS history based on the self-report of hypertension, hypercholesterolemia, hypertriglyceridemia, and diabetes; obesity was evaluated using weight-change trajectories throughout life. In addition, the four MS-typologies described for Mexican population were used. The association between MS with PC and histological PC differentiation was evaluated using independent multivariate logistic regression models. Results: MS history was associated with a high PC probability (OR 1.94; 95% CI 1.37-2.75). Lipid alterations, arterial hypertension, and a marked weight increase throughout life were associated with increased PC probability; however, only the marked weight increase was associated with more poorly differentiated PC (Gleason ≥8) (OR 2.79; 95% CI 1.50-5.17). Conclusion: Like other populations, in this Mexican study, MS and some of its components were identified as potential PC risk factors. MS-lipid alteration typology seems to be relevant; however, the novelty of this approach together with the retrospective nature of this study, indicate that a prospective evaluation of the MS typologies and PC association must be performed.
MeSH term(s)	Case-Control Studies ; Humans ; Hypertension/complications ; Hypertension/epidemiology ; Lipids ; Male ; Metabolic Syndrome/complications ; Metabolic Syndrome/epidemiology ; Prostatic Neoplasms/epidemiology ; Prostatic Neoplasms/pathology ; Retrospective Studies ; Risk Factors
Chemical Substances	Lipids
Language	English
Publishing date	2022-07-28
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1156844-6
ISSN	1873-5487 ; 0188-4409 ; 0188-0128
ISSN (online)	1873-5487
ISSN	0188-4409 ; 0188-0128
DOI	10.1016/j.arcmed.2022.07.003
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Article ; Online: Reply by the authors.

Olvera-Posada, Daniel / Rodriguez-Covarrubias, Francisco

Urology

2014 Volume 84, Issue 4, Page(s) 989

MeSH term(s)	Emphysema/surgery ; Humans ; Pyelonephritis/surgery
Language	English
Publishing date	2014-10
Publishing country	United States
Document type	Comment ; Letter
ZDB-ID	192062-5
ISSN	1527-9995 ; 0090-4295
ISSN (online)	1527-9995
ISSN	0090-4295
DOI	10.1016/j.urology.2014.07.016
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