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  1. Article ; Online: JMIR Perioperative Medicine: A Global Journal for Publishing Interdisciplinary Innovations, Research, and Perspectives.

    Rohatgi, Nidhi

    JMIR perioperative medicine

    2023  Volume 6, Page(s) e54344

    Abstract: JMIR Perioperative Medicine supports the dissemination of technological and data science-driven innovative research conducted by interdisciplinary teams in perioperative medicine. We invite contributions on a broad range of topics from clinicians, ... ...

    Abstract JMIR Perioperative Medicine supports the dissemination of technological and data science-driven innovative research conducted by interdisciplinary teams in perioperative medicine. We invite contributions on a broad range of topics from clinicians, scientists, and allied health professionals from across the globe.
    Language English
    Publishing date 2023-11-21
    Publishing country Canada
    Document type Editorial
    ISSN 2561-9128
    ISSN (online) 2561-9128
    DOI 10.2196/54344
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Perioperative Risk Calculators and the Art of Medicine.

    Rohatgi, Nidhi

    JAMA internal medicine

    2019  Volume 179, Issue 12, Page(s) 1619–1620

    MeSH term(s) Heart Disease Risk Factors ; Humans ; Risk Assessment
    Language English
    Publishing date 2019-10-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2699338-7
    ISSN 2168-6114 ; 2168-6106
    ISSN (online) 2168-6114
    ISSN 2168-6106
    DOI 10.1001/jamainternmed.2019.4914
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  3. Article ; Online: The promises and limitations of artificial intelligence for quality improvement, patient safety, and research in hospital medicine.

    Ma, Stephen P / Rohatgi, Nidhi / Chen, Jonathan H

    Journal of hospital medicine

    2024  

    Language English
    Publishing date 2024-05-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2233783-0
    ISSN 1553-5606 ; 1553-5592
    ISSN (online) 1553-5606
    ISSN 1553-5592
    DOI 10.1002/jhm.13404
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  4. Article ; Online: Perioperative Considerations for Patients with Severe Aortic Stenosis Undergoing Elective Noncardiac Surgery.

    Rohatgi, Nidhi / Smilowitz, Nathaniel R / Reejhsinghani, Risheen

    The American journal of medicine

    2023  Volume 136, Issue 10, Page(s) 960–962

    MeSH term(s) Humans ; Aortic Valve/surgery ; Aortic Valve Stenosis/surgery ; Elective Surgical Procedures ; Surgical Procedures, Operative ; Postoperative Complications/surgery
    Language English
    Publishing date 2023-06-25
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2023.05.017
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  5. Article ; Online: Management of Antiplatelet Therapy in Patients with Coronary Stents Undergoing Noncardiac Surgery.

    Rohatgi, Nidhi / Zehnder, James L / Smilowitz, Nathaniel R

    The American journal of medicine

    2022  Volume 135, Issue 9, Page(s) e305–e307

    MeSH term(s) Humans ; Perioperative Care ; Platelet Aggregation Inhibitors/therapeutic use ; Risk Factors ; Stents ; Surgical Procedures, Operative
    Chemical Substances Platelet Aggregation Inhibitors
    Language English
    Publishing date 2022-05-28
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2022.05.014
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  6. Article ; Online: Perioperative Cardiovascular Considerations Prior to Elective Noncardiac Surgery in Patients With a History of COVID-19.

    Rohatgi, Nidhi / Smilowitz, Nathaniel R / Reejhsinghani, Risheen

    JAMA surgery

    2022  Volume 157, Issue 3, Page(s) 187–188

    MeSH term(s) COVID-19 ; Cardiovascular Diseases/epidemiology ; Elective Surgical Procedures ; Humans ; Perioperative Care ; Postoperative Complications ; SARS-CoV-2
    Language English
    Publishing date 2022-01-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701841-6
    ISSN 2168-6262 ; 2168-6254
    ISSN (online) 2168-6262
    ISSN 2168-6254
    DOI 10.1001/jamasurg.2021.6953
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  7. Article ; Online: Cardiac risk assessment calculators: utility and limitations.

    Rohatgi, Nidhi / Cohn, Steven L

    International anesthesiology clinics

    2020  Volume 59, Issue 1, Page(s) 9–14

    MeSH term(s) Humans ; Risk Assessment ; Risk Factors
    Language English
    Publishing date 2020-11-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 210757-0
    ISSN 1537-1913 ; 0020-5907
    ISSN (online) 1537-1913
    ISSN 0020-5907
    DOI 10.1097/AIA.0000000000000309
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  8. Article: Tmem178 negatively regulates IL-1β production through inhibition of the NLRP3 inflammasome.

    Khanna, Kunjan / Yan, Hui / Mehra, Muneshwar / Rohatgi, Nidhi / Mbalaviele, Gabriel / Faccio, Roberta

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Objective: Inflammasomes modulate the release of bioactive IL-1β. Excessive IL-1β levels are detected in patients with systemic juvenile idiopathic arthritis (sJIA) and cytokine storm syndrome (CSS) with mutated and unmutated inflammasome components, ... ...

    Abstract Objective: Inflammasomes modulate the release of bioactive IL-1β. Excessive IL-1β levels are detected in patients with systemic juvenile idiopathic arthritis (sJIA) and cytokine storm syndrome (CSS) with mutated and unmutated inflammasome components, raising questions on the mechanisms of IL-1β regulation in these disorders.
    Methods: To investigate how the NLRP3 inflammasome is modulated in sJIA, we focused on Tmem178, a negative regulator of calcium levels in macrophages, and measured IL-1β and caspase-1 activation in wild-type (WT) and
    Results: TMEM178
    Conclusion: Downregulation of Tmem178 levels may represent a new biomarker to identify sJIA/CSS patients that could benefit from receiving drugs targeting inflammasome signaling.
    Language English
    Publishing date 2023-03-07
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.03.07.531385
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  9. Article ; Online: Merits of Surgical Comanagement of Patients With Hip Fracture by Dedicated Orthopaedic Hospitalists.

    Rohatgi, Nidhi / Weng, Yingjie / Kittle, Jessie / Ahuja, Neera

    Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews

    2021  Volume 5, Issue 3

    Abstract: Background: Rotating medical consultants, hospitalists or geriatricians, are involved in the care of patients with hip fracture, often after medical complications have already occurred. In August 2012, we implemented a unique surgical comanagement (SCM) ...

    Abstract Background: Rotating medical consultants, hospitalists or geriatricians, are involved in the care of patients with hip fracture, often after medical complications have already occurred. In August 2012, we implemented a unique surgical comanagement (SCM) model in which the same Internal Medicine hospitalists are dedicated year-round to the orthopaedic surgery service. We examine whether this SCM model was associated with a decrease in medical complications, length of stay, and inpatient mortality in patients with hip fracture admitted at our institution, compared with the previous model.
    Methods: We included 2,252 admissions to the orthopaedic surgery service with a hip fracture between 2009 and 2018 (757 pre-SCM and 1495 post-SCM). We adjusted for age, Charlson comorbidity score, and operating time in all regression analyses.
    Results: Mean Charlson comorbidity score (1.6 versus 1.2) and median case mix index (2.1 versus 1.9) were higher in the post-SCM group. A 32% decrease was observed in the odds of having ≥1 medical complication(s) (odds ratio, 0.68 [95% confidence interval, 0.50 to 0.91], P = 0.009) post-SCM. No change was observed in length of stay or inpatient mortality despite an increase in medical complexity post-SCM.
    Conclusion: Having dedicated orthopaedic hospitalists may contribute to fewer medical complications in patients with hip fracture.
    MeSH term(s) Hip Fractures/surgery ; Hospitalists ; Humans ; Length of Stay ; Orthopedics ; Patient Care Team
    Language English
    Publishing date 2021-03-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2898328-2
    ISSN 2474-7661 ; 1067-151X
    ISSN (online) 2474-7661
    ISSN 1067-151X
    DOI 10.5435/JAAOSGlobal-D-20-00231
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  10. Article ; Online: Characteristics associated with diagnostic yield of imaging for deep venous thrombosis and pulmonary embolism in the emergency department, hospital, and office settings: An Optum Clinformatics claims database study (2015-2019).

    Rohatgi, Nidhi / Dahlen, Alex / Berube, Caroline / Weng, Yingjie / Wintermark, Max / Ahuja, Neera

    Thrombosis research

    2023  Volume 224, Page(s) 4–12

    Abstract: Background: Different patient characteristics influence the decision to order diagnostic imaging for deep venous thrombosis (DVT) and pulmonary embolism (PE) in different settings (emergency department (ED), hospital, and office). Diagnostic yield is ... ...

    Abstract Background: Different patient characteristics influence the decision to order diagnostic imaging for deep venous thrombosis (DVT) and pulmonary embolism (PE) in different settings (emergency department (ED), hospital, and office). Diagnostic yield is defined as the proportion of tests that report positive results. We hypothesize different patient characteristics are associated with higher or lower diagnostic yield of imaging for DVT and PE in different settings.
    Methods: We used Optum Clinformatics™ national claims database (2015-2019) to assess the diagnostic yield of imaging for DVT and PE in three settings: (a) ED discharge, (b) Hospitalized, and (c) Office. We studied the patient characteristics associated with diagnostic yield using logistic regression.
    Results: Diagnostic imaging for DVT and PE was performed in 1,502,417 and 710,263 visits, respectively. Diagnostic yield for DVT and PE was 9.8 ± 0.1 % and 12.7 ± 0.1 %, respectively in the overall cohort. In the ED discharge, hospitalized, and office settings, diagnostic yield for DVT was 10.4 ± 0.1 %, 16.9 ± 0.1 %, and 6.5 ± 0.1 %, respectively, and that for PE 6.4 ± 0.1 %, 18.7 ± 0.1 %, and 8.8 ± 0.2 %, respectively. Of the patients who underwent imaging for DVT, higher diagnostic yield was more likely with thrombophilia, central venous access, and cancer. Of the patients who underwent imaging for PE, higher diagnostic yield was most likely with thrombophilia, respiratory failure, and heart failure or acute myocardial infarction.
    Conclusions: In each setting, different patient characteristics influence the diagnostic yield of imaging for DVT and PE and can inform clinical practice. Judicious use of imaging for DVT and PE could reduce costs and avoid exposure to radiation and contrast.
    MeSH term(s) Humans ; Venous Thrombosis/diagnostic imaging ; Venous Thrombosis/complications ; Pulmonary Embolism/diagnostic imaging ; Pulmonary Embolism/complications ; Diagnostic Imaging ; Hospitals ; Thrombophilia/complications ; Risk Factors
    Language English
    Publishing date 2023-02-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 121852-9
    ISSN 1879-2472 ; 0049-3848
    ISSN (online) 1879-2472
    ISSN 0049-3848
    DOI 10.1016/j.thromres.2023.02.004
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