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  1. Article: A novel speech analysis algorithm to detect cognitive impairment in a Spanish population.

    Kaser, Alyssa N / Lacritz, Laura H / Winiarski, Holly R / Gabirondo, Peru / Schaffert, Jeff / Coca, Alberto J / Jiménez-Raboso, Javier / Rojo, Tomas / Zaldua, Carla / Honorato, Iker / Gallego, Dario / Nieves, Emmanuel Rosario / Rosenstein, Leslie D / Cullum, C Munro

    Frontiers in neurology

    2024  Volume 15, Page(s) 1342907

    Abstract: Objective: Early detection of cognitive impairment in the elderly is crucial for diagnosis and appropriate care. Brief, cost-effective cognitive screening instruments are needed to help identify individuals who require further evaluation. This study ... ...

    Abstract Objective: Early detection of cognitive impairment in the elderly is crucial for diagnosis and appropriate care. Brief, cost-effective cognitive screening instruments are needed to help identify individuals who require further evaluation. This study presents preliminary data on a new screening technology using automated voice recording analysis software in a Spanish population.
    Method: Data were collected from 174 Spanish-speaking individuals clinically diagnosed as cognitively normal (CN,
    Results: Mean logit algorithm scores were significantly different across groups in the testing sample (
    Conclusion: Findings provide initial support for the utility of this automated speech analysis algorithm as a screening tool for cognitive impairment in Spanish speakers. Additional study is needed to validate this technology in larger and more diverse clinical populations.
    Language English
    Publishing date 2024-04-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2024.1342907
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Nonresonant background suppression for coherent anti-Stokes Raman scattering microscopy using a multi-wavelength time-lens source.

    Li, Bo / Charan, Kriti / Wang, Ke / Rojo, Tomás / Sinefeld, David / Xu, Chris

    Optics express

    2016  Volume 24, Issue 23, Page(s) 26687–26695

    Abstract: We demonstrate a robust, all-fiber, two-wavelength time-lens source for background-free coherent anti-Stokes Raman scattering imaging. The time-lens source generates two picosecond pulse trains simultaneously: one at 1064 nm and the other tunable between ...

    Abstract We demonstrate a robust, all-fiber, two-wavelength time-lens source for background-free coherent anti-Stokes Raman scattering imaging. The time-lens source generates two picosecond pulse trains simultaneously: one at 1064 nm and the other tunable between 1040 nm and 1075 nm (~400 mW for each wavelength). When synchronized to a mode-locked Ti:Sapphire laser, the two wavelengths are used to obtain on- and off-resonance coherent anti-Stokes Raman scattering images. Real-time subtraction of the nonresonant background in the coherent anti-Stokes Raman scattering image is achieved by the synchronization of the pixel clock and the time-lens source. Background-free coherent anti-Stokes Raman scattering imaging of sebaceous glands in ex vivo mouse tissue is demonstrated.
    Language English
    Publishing date 2016-11-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.24.026687
    Database MEDical Literature Analysis and Retrieval System OnLINE

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