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  1. Article: Is bias inherent in HCFA-sponsored research?

    Rollings, R C

    JAMA

    1991  Volume 266, Issue 1, Page(s) 63–64

    MeSH term(s) Aged ; Antipsychotic Agents/therapeutic use ; Bias ; Centers for Medicare and Medicaid Services (U.S.) ; Humans ; Nursing Homes ; Research ; United States
    Chemical Substances Antipsychotic Agents
    Language English
    Publishing date 1991-07-03
    Publishing country United States
    Document type Letter
    ZDB-ID 2958-0
    ISSN 1538-3598 ; 0098-7484 ; 0254-9077 ; 0002-9955
    ISSN (online) 1538-3598
    ISSN 0098-7484 ; 0254-9077 ; 0002-9955
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Guidelines for training in cardiovascular magnetic resonance (CMR).

    Kim, R J / Simonetti, O P / Westwood, M / Kramer, C M / Narang, A / Friedrich, M G / Powell, A J / Carr, J C / Schulz-Menger, J / Nagel, E / Chan, W S / Bremerich, J / Ordovas, K G / Rollings, R C / Patel, A R / Ferrari, V A

    Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance

    2018  Volume 20, Issue 1, Page(s) 57

    Abstract: These "Guidelines for training in Cardiovascular Magnetic Resonance" were developed by the Certification Committee of the Society for Cardiovascular Magnetic Resonance (SCMR) and approved by the SCMR Board of Trustees. ...

    Abstract These "Guidelines for training in Cardiovascular Magnetic Resonance" were developed by the Certification Committee of the Society for Cardiovascular Magnetic Resonance (SCMR) and approved by the SCMR Board of Trustees.
    MeSH term(s) Cardiology/education ; Cardiology/standards ; Certification/methods ; Certification/standards ; Clinical Competence ; Curriculum ; Education, Medical, Graduate/methods ; Education, Medical, Graduate/standards ; Humans ; Internship and Residency/standards ; Magnetic Resonance Imaging
    Language English
    Publishing date 2018-08-16
    Publishing country England
    Document type Guideline ; Journal Article
    ZDB-ID 1458034-2
    ISSN 1532-429X ; 1097-6647
    ISSN (online) 1532-429X
    ISSN 1097-6647
    DOI 10.1186/s12968-018-0481-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Coronary artery vasospasm complicating acute myocarditis. A rare association.

    Ferguson, D W / Farwell, A P / Bradley, W A / Rollings, R C

    The Western journal of medicine

    1988  Volume 148, Issue 6, Page(s) 664–669

    Abstract: A 17-year-old boy had a 2-day prodrome of fever and mild sore throat followed by 2 episodes of severe anginal chest discomfort and substantial transient ST-segment elevations in the anterior leads of the electrocardiogram. A subsequent evaluation showed ... ...

    Abstract A 17-year-old boy had a 2-day prodrome of fever and mild sore throat followed by 2 episodes of severe anginal chest discomfort and substantial transient ST-segment elevations in the anterior leads of the electrocardiogram. A subsequent evaluation showed the 2 episodes were most likely coronary vasospasm complicating acute viral myocarditis.
    MeSH term(s) Acute Disease ; Adolescent ; Coronary Vasospasm/etiology ; Electrocardiography ; Humans ; Male ; Myocarditis/complications ; Myocarditis/etiology ; Virus Diseases/complications
    Language English
    Publishing date 1988-06
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 189235-6
    ISSN 1476-2978 ; 0093-0415 ; 0008-1264
    ISSN (online) 1476-2978
    ISSN 0093-0415 ; 0008-1264
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Right ventricular hypertrophy detected by echocardiography in patients with newly diagnosed obstructive sleep apnea.

    Berman, E J / DiBenedetto, R J / Causey, D E / Mims, T / Conneff, M / Goodman, L S / Rollings, R C

    Chest

    1991  Volume 100, Issue 2, Page(s) 347–350

    Abstract: We used polysomnography, echocardiography and ventilatory measurements to study 50 patients suspected of having OSA to determine a link to RVH. Twenty-eight patients (56 percent) had OSA and 20 (71 percent) of those had isolated RVH. We evaluated ... ...

    Abstract We used polysomnography, echocardiography and ventilatory measurements to study 50 patients suspected of having OSA to determine a link to RVH. Twenty-eight patients (56 percent) had OSA and 20 (71 percent) of those had isolated RVH. We evaluated patients with RVH and divided them into two groups, those with apnea and those without apnea. The patients with sleep apnea were younger, weighed more, had greater BSA and had lower average oxygen saturations during the sleep study period. We divided the group with apnea into those with RVH and those without it. Those patients with RVH had a higher AI, longer average apnea time, a greater duration of longest apnea and a lower average oxygen saturation for the period of the sleep study. In addition, those with RVH had a lower average oxygen saturation during each apneic episode with a p value equaling 0.09.
    MeSH term(s) Adolescent ; Adult ; Age Factors ; Aged ; Body Surface Area ; Cardiomegaly/diagnostic imaging ; Cardiomegaly/physiopathology ; Echocardiography ; Electrocardiography ; Electroencephalography ; Electrooculography ; Female ; Humans ; Male ; Middle Aged ; Oxygen Consumption/physiology ; Prospective Studies ; Pulmonary Ventilation/physiology ; Respiratory Mechanics/physiology ; Sleep Apnea Syndromes/diagnosis ; Sleep Apnea Syndromes/diagnostic imaging ; Sleep Apnea Syndromes/physiopathology ; Ventricular Function, Right/physiology
    Language English
    Publishing date 1991-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1378/chest.100.2.347
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Effect of alanine concentration independent of changes in insulin and glucagon on alanine and glucose homeostasis in the conscious dog.

    Diamond, M P / Rollings, R C / Steiner, K E / Williams, P E / Lacy, W W / Cherrington, A D

    Metabolism: clinical and experimental

    1988  Volume 37, Issue 1, Page(s) 28–33

    Abstract: The effect of an alanine load per se on hepatic alanine balance and hepatic glucose production is unclear. To examine this question, alanine was infused into six postabsorptive dogs at a rate of 6 mumol/kg-min, while maintaining insulin and glucagon ... ...

    Abstract The effect of an alanine load per se on hepatic alanine balance and hepatic glucose production is unclear. To examine this question, alanine was infused into six postabsorptive dogs at a rate of 6 mumol/kg-min, while maintaining insulin and glucagon levels using the pancreatic clamp technique. The arterial alanine concentration rose from a basal level of 227 +/- 16 mumol/L to 497 +/- 40 mumol/L during alanine infusion (P less than .01). The net hepatic fractional extraction of alanine remained unchanged, while hepatic alanine uptake increased from 3.0 +/- 0.3 to 6.0 +/- 0.4 mumol/kg-min (P less than .01). Conversion of alanine into glucose increased 87% to 2.7 +/- 0.3 mumol/kg-min during alanine infusion (P less than .01) while gluconeogenic efficiency remained essentially unchanged. Despite the increased gluconeogenic rate, the total rate of glucose production was unchanged. These data suggest that an increase in the alanine load to the liver causes a proportional increase in net hepatic alanine uptake and the gluconeogenic rate, but that in an overnight fasted animal this increase is insufficient to significantly increase glucose production.
    MeSH term(s) Alanine/administration & dosage ; Alanine/blood ; Alanine/metabolism ; Animals ; Blood Glucose/analysis ; Consciousness ; Dogs ; Fasting ; Glucagon/blood ; Gluconeogenesis ; Glucose/metabolism ; Homeostasis ; Insulin/blood ; Liver/metabolism ; Research Design
    Chemical Substances Blood Glucose ; Insulin ; Glucagon (9007-92-5) ; Glucose (IY9XDZ35W2) ; Alanine (OF5P57N2ZX)
    Language English
    Publishing date 1988-01
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 80230-x
    ISSN 1532-8600 ; 0026-0495
    ISSN (online) 1532-8600
    ISSN 0026-0495
    DOI 10.1016/0026-0495(88)90025-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Dichloroacetate--its in vivo effects on carbohydrate metabolism in the conscious dog.

    Diamond, M P / Rollings, R C / Erlendson, L / Williams, P E / Lacy, W W / Rabin, D / Cherrington, A D

    Diabetes

    1980  Volume 29, Issue 9, Page(s) 702–709

    Abstract: The effects of sodium dichloroacetate (DCA) on carbohydrate metabolism in conscious, 48-h-fasted dogs were examined using the hepatic A-V difference technique and a double isotope infusion technique (3H-glucose to measure glucose production and 14C- ... ...

    Abstract The effects of sodium dichloroacetate (DCA) on carbohydrate metabolism in conscious, 48-h-fasted dogs were examined using the hepatic A-V difference technique and a double isotope infusion technique (3H-glucose to measure glucose production and 14C-alanine to assess gluconeogenesis). DCA infusion (0.4 mg/kg-min) resulted in an 82 +/- 1% fall in the arterial plasma alanine level and a 53 +/- 8% fall in the arterial whole blood lactate level. Hepatic uptake of alanine and lactate fell 67 +/- 5% and 59 +/- 15%, respectively, although the fractional extraction of these intermediates was not altered. DCA decreased the conversion of circulating alanine and lactate to glucose but by only 41 +/- 7%, suggesting that a slight increase in the efficiency of the intrahepatic gluconeogenic process took place. This may be explained by the decrease in the plasma insulin level (39 +/- 9%) that occurred in the presence of an unchanged plasma glucagon concentration. Despite the substantial fall in the levels of gluconeogenic precursors in blood and the considerable decrease in their rate of conversion to glucose, the overall rates of glucose production and the blood glucose concentration were not altered by DCA. These data indicate that the alanine and lactate supplied by the periphery after a 48 h fast in the dog are not essential for the acute maintenance of glucose production or euglycemia. They suggest, further, that a compensatory increase in glucose production can occur by drawing on an alternate intrahepatic carbon source, the nature of which and signal for which remain unclear.
    MeSH term(s) Acetates/pharmacology ; Alanine/metabolism ; Amino Acids/blood ; Animals ; Dichloroacetic Acid/pharmacology ; Dogs ; Female ; Glucagon/blood ; Gluconeogenesis/drug effects ; Glucose/metabolism ; Glycerol/metabolism ; Insulin/blood ; Kinetics ; Liver/metabolism ; Male
    Chemical Substances Acetates ; Amino Acids ; Insulin ; Glucagon (9007-92-5) ; Dichloroacetic Acid (9LSH52S3LQ) ; Glucose (IY9XDZ35W2) ; Alanine (OF5P57N2ZX) ; Glycerol (PDC6A3C0OX)
    Language English
    Publishing date 1980-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80085-5
    ISSN 1939-327X ; 0012-1797
    ISSN (online) 1939-327X
    ISSN 0012-1797
    DOI 10.2337/diab.29.9.702
    Database MEDical Literature Analysis and Retrieval System OnLINE

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