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  1. Article ; Online: Seroprevalence and risk factors associated with hepatitis C: a cross-sectional study of persons who inject drugs in Puerto Rico, 2018.

    Colón-López, Vivian / Alvelo-Fernández, Paola M / Centeno-Alvarado, Nadia / Agudelo Salas, Ivony Y / Rolón Colón, Yadira / Pabón Martínez, María / Rodríguez-Lebrón, Jorge L / Reyes-Pulliza, Juan C

    BMC public health

    2023  Volume 23, Issue 1, Page(s) 704

    Abstract: Background: People Who Inject Drugs (PWID) are at a higher risk of acquiring bloodborne infections. We aimed to estimate the seroprevalence of the Hepatitis C Virus (HCV) in PWID and identify correlates and risk factors using data from the Puerto Rico ... ...

    Abstract Background: People Who Inject Drugs (PWID) are at a higher risk of acquiring bloodborne infections. We aimed to estimate the seroprevalence of the Hepatitis C Virus (HCV) in PWID and identify correlates and risk factors using data from the Puerto Rico National HIV Behavioral Surveillance System, PWID cycle 5, conducted in 2018.
    Methods: A total of 502 San Juan Metropolitan Statistical Area participants were recruited through the Respondent Driven Sampling method. Sociodemographic, health-related, and behavioral characteristics were assessed. Testing for HCV antibodies was completed after the face-to-face survey. Descriptive and logistic regression analyses were performed.
    Results: Overall seroprevalence of HCV was 76.5% (95% CI: 70.8-81.4%). A significantly (p < 0.05) higher HCV seroprevalence was observed among PWID with the following characteristics: heterosexuals (78.5%), high school graduates (81.3%), tested for sexually transmitted infections (STI) in the past 12 months (86.1%), frequent speedball injection (79.4%), and knowing the HCV serostatus of the last sharing partner (95.4%). Adjusted logistic regression models showed that having completed high school and reported STI testing in the past 12 months were significantly associated with HCV infection (OR
    Conclusions: We report a high seroprevalence of HCV infection in PWID. Social health disparities and potential missed opportunities validate the continuing call for local action for public health and prevention strategies.
    MeSH term(s) Humans ; Hepacivirus ; Drug Users ; Cross-Sectional Studies ; HIV Infections/epidemiology ; Substance Abuse, Intravenous/complications ; Puerto Rico/epidemiology ; Seroepidemiologic Studies ; Risk-Taking ; Hepatitis C ; Risk Factors ; Surveys and Questionnaires ; Prevalence
    Language English
    Publishing date 2023-04-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-023-15341-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Social Media and Mobile-App use for Sexual Encounters among Men Who Have Sex With Men in Puerto Rico.

    Colón-López, Vivian / Centeno-Alvarado, Nadia / Agudelo-Salas, Ivony Y / Canario de la Torre, Maureen M / Miranda de León, Sandra / Rolón-Colón, Yadira / Rodríguez, Jorge / Pabón-Martínez, María

    Puerto Rico health sciences journal

    2021  Volume 40, Issue 3, Page(s) 136–141

    Abstract: Objective: To describe the use and frequency of use of mobile apps (internetand/ or smartphone-based geospatial networking apps) among men who have sex with men (MSM) and how these platforms are used to engage with sexual partners in PR.: Methods: A ... ...

    Abstract Objective: To describe the use and frequency of use of mobile apps (internetand/ or smartphone-based geospatial networking apps) among men who have sex with men (MSM) and how these platforms are used to engage with sexual partners in PR.
    Methods: A local module including questions regarding mobile apps and sexual engagement and derived from the 2017 Puerto Rico National HIV Behavioral Surveillance System, fifth MSM cycle, was used for this analysis. A subsample of 127 eligible participants was recruited through venue-based sampling and assented to participate. Univariate analysis was used to evaluate sociodemographic and behavioral characteristics, HIV testing, and the ways in which mobile apps are used to find sexual partners.
    Results: The participants' median age was 35 years, with a standard deviation of ±11.37 years. Most of our sample (97%) had had anal sex with at least 1 partner in the last 12 months, and 76% of them had had condomless anal sex. Over three fourths (81%) reported using apps for sexual encounters, while 45% stated that the most frequently used app was Grindr. Of the participants who had used apps for sexual encounters, 57% had met 5 or more sexual partners through apps in their lifetime.
    Conclusion: This study shows that there is a need for further research to understand the habits of this population in PR regarding the use of apps to find sexual partners and, also, as a possible way to develop strategies for prevention and health promotion in this group.
    MeSH term(s) Adult ; HIV Infections/epidemiology ; HIV Infections/prevention & control ; Homosexuality, Male/psychology ; Humans ; Internet ; Male ; Mobile Applications ; Puerto Rico ; Sexual Behavior ; Sexual Partners ; Smartphone ; Social Media ; Social Networking
    Language English
    Publishing date 2021-11-18
    Publishing country Puerto Rico
    Document type Journal Article
    ZDB-ID 639137-0
    ISSN 2373-6011 ; 0738-0658
    ISSN (online) 2373-6011
    ISSN 0738-0658
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Rural and urban injection drug use in Puerto Rico: Network implications for human immunodeficiency virus and hepatitis C virus infection.

    Thrash, Courtney / Welch-Lazoritz, Melissa / Gauthier, Gertrude / Khan, Bilal / Abadie, Roberto / Dombrowski, Kirk / De Leon, Sandra Miranda / Rolon Colon, Yadira

    Journal of ethnicity in substance abuse

    2017  Volume 17, Issue 2, Page(s) 199–222

    Abstract: Understanding the short- and long-term transmission dynamics of blood-borne illnesses in network contexts represents an important public health priority for people who inject drugs and the general population that surrounds them. The purpose of this ... ...

    Abstract Understanding the short- and long-term transmission dynamics of blood-borne illnesses in network contexts represents an important public health priority for people who inject drugs and the general population that surrounds them. The purpose of this article is to compare the risk networks of urban and rural people who inject drugs in Puerto Rico. In the current study, network characteristics are drawn from the sampling "trees" used to recruit participants to the study. We found that injection frequency is the only factor significantly related to clustering behavior among both urban and rural people who inject drugs.
    MeSH term(s) Adolescent ; Adult ; Aged ; Female ; HIV Infections/epidemiology ; HIV Infections/transmission ; Hepatitis C/epidemiology ; Hepatitis C/transmission ; Humans ; Male ; Middle Aged ; Puerto Rico/epidemiology ; Risk ; Rural Population/statistics & numerical data ; Substance Abuse, Intravenous/epidemiology ; Urban Population/statistics & numerical data ; Young Adult
    Language English
    Publishing date 2017-06-30
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2052900-4
    ISSN 1533-2659 ; 1533-2640
    ISSN (online) 1533-2659
    ISSN 1533-2640
    DOI 10.1080/15332640.2017.1326864
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Differential access to syringe exchange and other prevention activities among people who inject drugs in rural and urban areas of Puerto Rico.

    Welch-Lazoritz, Melissa / Habecker, Patrick / Dombrowski, Kirk / Rivera Villegas, Angelica / Davila, Carmen Ana / Rolón Colón, Yadira / Miranda De León, Sandra

    The International journal on drug policy

    2017  Volume 43, Page(s) 16–22

    Abstract: Background: Injection drug use and its associated blood-borne infections has become a rapidly increasing problem in rural areas of the US recently. Syringe exchange programs have been shown to be effective for reducing transmission of blood borne ... ...

    Abstract Background: Injection drug use and its associated blood-borne infections has become a rapidly increasing problem in rural areas of the US recently. Syringe exchange programs have been shown to be effective for reducing transmission of blood borne infections, however access to these prevention efforts may be limited in rural areas.
    Methods: This paper utilizes two separate community samples of people who inject drugs (PWID) in Puerto Rico to achieve the following research objectives: (1) compare rural and urban access to syringe exchange programs, free sterile syringes and other HIV/HCV prevention activities, and (2) examine whether utilization of prevention activities is associated with lower injection risk behaviors. Two samples were recruited with RDS (n=315 rural sample; n=512 urban sample) and included adults aged 18 years and older who have injected drugs within the past month.
    Results: 78.5% of the urban sample utilized a syringe exchange program in the past year, compared to 58.4% of the rural sample (p<.001). 71.4% of the urban sample received free sterile needles, compared to 58.4% of the rural sample (p<.001). 66% of the urban sample received free works compared to 59% of the rural sample (p=.034). 29% of urban PWID had a conversation with an outreach worker about HIV prevention compared to 18% of the rural sample (p<0.001). Receiving free needles significantly increases the frequency of using a sterile needle to inject (p<.001).
    Conclusion: Urban PWID were significantly more likely to have utilized syringe exchange programs, received free sterile needles, received free works, and to have talked about HIV prevention with an outreach worker during the past year than PWID residing in rural areas. Individuals who accessed these prevention activities were significantly less likely to exhibit risky injection behavior. Policy implications call for increasing access to prevention services in rural areas to reduce disease transmission.
    MeSH term(s) Adult ; HIV Infections/prevention & control ; Health Services Accessibility ; Hepatitis C/prevention & control ; Humans ; Needle-Exchange Programs/statistics & numerical data ; Needles/supply & distribution ; Puerto Rico ; Risk-Taking ; Rural Population/statistics & numerical data ; Substance Abuse, Intravenous/complications ; Syringes/supply & distribution ; Urban Population/statistics & numerical data
    Language English
    Publishing date 2017-02-01
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2010000-0
    ISSN 1873-4758 ; 0955-3959
    ISSN (online) 1873-4758
    ISSN 0955-3959
    DOI 10.1016/j.drugpo.2016.12.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: New Diagnoses among HIV+ Men and Women in Puerto Rico: Data from the HIV Surveillance System 2003-2014.

    Colón-López, Vivian / Miranda-De León, Sandra / Machin-Rivera, Mark / Soto-Abreu, Roxana / Marrero-Cajigas, Edna L / Rolón-Colón, Yadira / Valencia-Torres, Ileska M / Suárez-Pérez, Erick L

    Puerto Rico health sciences journal

    2019  Volume 38, Issue 1, Page(s) 33–39

    Abstract: Objective: Describe the age-standardized rates of new HIV diagnoses and compare sex and time disparities using data from the HIV/AIDS Surveillance System in Puerto Rico (PR).: Methods: The study comprises data of new HIV diagnoses of persons 13 years ...

    Abstract Objective: Describe the age-standardized rates of new HIV diagnoses and compare sex and time disparities using data from the HIV/AIDS Surveillance System in Puerto Rico (PR).
    Methods: The study comprises data of new HIV diagnoses of persons 13 years of age and older in PR reported from 2003-2014. Other variables included were age, sex, and health regions. We computed male to female ratio of new HIV diagnoses and assessed the trends in new HIV diagnoses using the annual percent change (APC) of the age-standardized rates (ASRs). The relative risk (RR) was estimated with 95% confidence intervals using Poisson regression models to assess the risk of new HIV diagnoses.
    Results: The highest HIV diagnosis rates were observed in the metropolitan area. These rates decreased overall for both sexes for the periods 2007 onward. The risk of getting a new HIV diagnosis was significantly higher among males, ranging from an increased risk of more than 50% to almost 5-fold (p<0.05). Overall, a trend was observed in the 2011-2014 period were the risk increases as the age decreases. For the 13-24 age group, we observed a significant increased risk in new HIV diagnosis of 53% in the 2011-2014 period, when compared to 2003-2006 (p<0.05).
    Conclusion: Our findings suggest a shift in the risk of getting a HIV diagnosis from older to younger males. A possible explanation could be that HIV spread among young men that have sex with men might be increasing. Targeted prevention strategies should be implemented in this age group.
    MeSH term(s) Adolescent ; Adult ; Age Factors ; Female ; HIV Infections/epidemiology ; Humans ; Male ; Middle Aged ; Population Surveillance ; Puerto Rico/epidemiology ; Risk Factors ; Sex Factors ; Sexual and Gender Minorities/statistics & numerical data ; Young Adult
    Language English
    Publishing date 2019-03-28
    Publishing country Puerto Rico
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 639137-0
    ISSN 2373-6011 ; 0738-0658
    ISSN (online) 2373-6011
    ISSN 0738-0658
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Factors Associated With Recent Human Immunodeficiency Virus Testing Among Men Who Have Sex With Men in Puerto Rico, National Human Immunodeficiency Virus Behavioral Surveillance System, 2011.

    Chapin-Bardales, Johanna / Sanchez, Travis / Paz-Bailey, Gabriela / Hageman, Kathy / Spiller, Michael W / Rolon-Colon, Yadira / Miranda de Leon, Sandra

    Sexually transmitted diseases

    2016  Volume 43, Issue 6, Page(s) 346–352

    Abstract: Background: Annual human immunodeficiency virus (HIV) testing is considered a key strategy for HIV prevention for men who have sex with men (MSM). In Puerto Rico, HIV research has primarily focused on injection drug use, yet male-to-male sexual ... ...

    Abstract Background: Annual human immunodeficiency virus (HIV) testing is considered a key strategy for HIV prevention for men who have sex with men (MSM). In Puerto Rico, HIV research has primarily focused on injection drug use, yet male-to-male sexual transmission has been increasing in recent years.
    Methods: Cross-sectional data from the National HIV Behavioral Surveillance system collected in 2011 in San Juan, Puerto Rico, were analyzed to identify factors associated with HIV testing in the past 12 months (recent testing).
    Results: Overall, 50% of participants were tested recently. In the multivariate analysis, testing recently was associated with having multiple partners in the past 12 months (adjusted prevalence ratio [aPR] [≥4 vs 1 partner] = 1.5; 95% confidence interval [95% CI], 1.2-2.0), visiting a health care provider in the past 12 months (aPR, 1.4; 95% CI, 1.04-1.8), and disclosing male-male attraction/sex to a health care provider (aPR< 1.4; 95% CI, 1.1-1.7).
    Conclusions: Human immunodeficiency virus testing was suboptimal among MSM in San Juan. Strategies to increase HIV testing among MSM may include promoting HIV testing for all sexually active MSM including those with fewer partners, increasing utilization of the healthcare system, and improving patient-provider communication.
    MeSH term(s) Adolescent ; Adult ; Cross-Sectional Studies ; Epidemiological Monitoring ; HIV Infections/diagnosis ; HIV Infections/epidemiology ; HIV Infections/prevention & control ; Homosexuality, Male ; Humans ; Male ; Mass Screening ; Prevalence ; Puerto Rico ; Sexual Behavior ; Sexual Partners ; Sexual and Gender Minorities ; Substance Abuse, Intravenous ; Young Adult
    Language English
    Publishing date 2016-05-20
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 435191-5
    ISSN 1537-4521 ; 0148-5717
    ISSN (online) 1537-4521
    ISSN 0148-5717
    DOI 10.1097/OLQ.0000000000000451
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Mortality Disparities among HIV+ Men and Women in Puerto Rico: Data from the HIV/AIDS Surveillance System 2003-2014.

    Colón-López, Vivian / Miranda-De León, Sandra / Machin-Rivera, Mark / Marrero, Edna / Rolón-Colón, Yadira / Valencia-Torres, Ileska M / Suárez, Erick

    Puerto Rico health sciences journal

    2017  Volume 36, Issue 1, Page(s) 24–28

    Abstract: Objective: Describe the trend of the indirect standardized death rate of HIV for different modes of HIV transmission from 2003 to 2014 in Puerto Rico. Estimate the magnitude of the association between mode of HIV transmission and mortality at different ... ...

    Abstract Objective: Describe the trend of the indirect standardized death rate of HIV for different modes of HIV transmission from 2003 to 2014 in Puerto Rico. Estimate the magnitude of the association between mode of HIV transmission and mortality at different time periods in Puerto Rico.
    Methods: ISDRs by sex and mode of transmission were computed using data from the PR National HIV/AIDS Surveillance System (2003-2014). Poisson models were used to assess the annual percent change of the ISDRs and RRs by sex.
    Results: Injection drug users (IDUs) showed the highest decrease in ISDR (-10.56, for men; -9.32 for women). Compared to men who have sex with men (MSM), IDU men also had the highest RR, representing an increase of 93% (2009-2011) (RRIDU vs MSM: 1.93, 95% CI: 1.66-2.23). Compared to women who were IDUs, heterosexual (HET) women had less risk of dying (48% for the period of 2006 to 2008).
    Conclusion: Mortality has been decreasing in each mode of transmission for both sexes. In addition, though IDUs present the highest decrease of ISDR, it is still the group whose members have the highest risk of dying, both men and women. To better describe health disparities as related to HIV/AIDS mortality, future analyses should be performed using specific causes of death and the evaluation of other relevant clinical and sociodemographic factors. Such data might increase our understanding of mortality in people with HIV/AIDS on the island, as well as help in future efforts to develop intervention strategies for the aforementioned risk groups.
    MeSH term(s) Acquired Immunodeficiency Syndrome/epidemiology ; Acquired Immunodeficiency Syndrome/mortality ; Acquired Immunodeficiency Syndrome/transmission ; Adolescent ; Adult ; Female ; HIV Infections/epidemiology ; HIV Infections/mortality ; HIV Infections/transmission ; Health Status Disparities ; Humans ; Male ; Middle Aged ; Poisson Distribution ; Population Surveillance ; Puerto Rico/epidemiology ; Risk Factors ; Sexual Behavior/statistics & numerical data ; Sexual and Gender Minorities/statistics & numerical data ; Substance Abuse, Intravenous/epidemiology ; Time Factors ; Young Adult
    Language English
    Publishing date 2017-03-07
    Publishing country Puerto Rico
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 639137-0
    ISSN 0738-0658
    ISSN 0738-0658
    Database MEDical Literature Analysis and Retrieval System OnLINE

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