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  1. Book: Store-operated Ca²⁺ entry (SOCE) pathways

    Groschner, Klaus / Graier, Wolfgang / Romanin, Christoph

    emerging signaling concepts in human (patho)physiology

    (Advances in experimental medicine and biology ; 993)

    2017  

    Author's details Klaus Groschner, Wolfgang Graier, Christoph Romanin editors
    Series title Advances in experimental medicine and biology ; 993
    Collection
    Keywords Calcium Signaling ; STIM-Orai Pathway ; TRP Pathways ; Crystal Structure Core Complex ; Calcium Entry Pathways
    Subject code 570
    Language English
    Size xxix, 645 Seiten, Illustrationen, 23.5 cm x 15.5 cm
    Edition Second Edition
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT019341157
    ISBN 978-3-319-57731-9 ; 3-319-57731-X
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Online ; E-Book: Store-Operated Ca²⁺ Entry (SOCE) pathways

    Groschner, Klaus / Graier, Wolfgang F. / Romanin, Christoph

    emerging signaling concepts in human (patho)physiology

    (Advances in experimental medicine and biology ; 993)

    2017  

    Author's details Klaus Groschner, Wolfgang F. Graier, Christoph Romanin editors
    Series title Advances in experimental medicine and biology ; 993
    Collection
    Keywords Life sciences ; Cardiology ; Medical biochemistry ; Cell biology
    Subject code 571.6
    Language English
    Size 1 Online-Ressource (xxix, 645 Seiten), Illustrationen
    Edition Second edition
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019494694
    ISBN 978-3-319-57732-6 ; 9783319577319 ; 3-319-57732-8 ; 331957731X
    DOI 10.1007/978-3-319-57732-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book: Store-operated Ca2+ entry (SOCE) pathways

    Groschner, Klaus / Graier, Wolfgang F. / Romanin, Christoph

    emerging signaling concepts in human (patho)physiology

    2012  

    Author's details Klaus Groschner ; Wolfgang F. Graier ; Christoph Romanin
    Language English
    Size XXI, 481 S. : Ill., graph. Darst., 24 cm
    Publisher Springer
    Publishing place Wien
    Publishing country Austria
    Document type Book
    HBZ-ID HT017174377
    ISBN 978-3-7091-0961-8 ; 3-7091-0961-2 ; 9783709109625 ; 3709109620
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Tubular aggregate myopathy mutant unveils novel activation and inactivation mechanisms of Orai1.

    Derler, Isabella / Romanin, Christoph

    Cell calcium

    2023  Volume 112, Page(s) 102739

    MeSH term(s) Humans ; Mutation/genetics ; Miosis ; Myopathies, Structural, Congenital/genetics ; ORAI1 Protein/genetics ; Stromal Interaction Molecule 1/genetics ; Calcium/metabolism
    Chemical Substances ORAI1 Protein ; Stromal Interaction Molecule 1 ; Calcium (SY7Q814VUP) ; ORAI1 protein, human
    Language English
    Publishing date 2023-04-07
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 757687-0
    ISSN 1532-1991 ; 0143-4160
    ISSN (online) 1532-1991
    ISSN 0143-4160
    DOI 10.1016/j.ceca.2023.102739
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: "Functional communication between IP

    Humer, Christina / Romanin, Christoph

    Cell calcium

    2022  Volume 104, Page(s) 102574

    Abstract: The family of stromal interaction molecules (STIMs), comprising the homologs STIM1 and STIM2 with their different isoforms, has an intricate role in cellular calcium ( ... ...

    Abstract The family of stromal interaction molecules (STIMs), comprising the homologs STIM1 and STIM2 with their different isoforms, has an intricate role in cellular calcium (Ca
    MeSH term(s) Calcium/metabolism ; Calcium Signaling ; Cell Communication ; Membrane Proteins/metabolism ; ORAI1 Protein/metabolism ; Stromal Interaction Molecule 1/metabolism ; Stromal Interaction Molecule 2/metabolism
    Chemical Substances Membrane Proteins ; ORAI1 Protein ; Stromal Interaction Molecule 1 ; Stromal Interaction Molecule 2 ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2022-03-29
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 757687-0
    ISSN 1532-1991 ; 0143-4160
    ISSN (online) 1532-1991
    ISSN 0143-4160
    DOI 10.1016/j.ceca.2022.102574
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The many states of STIM1.

    Fahrner, Marc / Romanin, Christoph

    eLife

    2021  Volume 10

    Abstract: Harnessing single-molecule FRET illuminates the structural changes necessary for a protein to fine-tune the influx of calcium when reserves inside a cell run low. ...

    Abstract Harnessing single-molecule FRET illuminates the structural changes necessary for a protein to fine-tune the influx of calcium when reserves inside a cell run low.
    MeSH term(s) Calcium/metabolism ; Calcium Channels/metabolism ; Calcium Signaling ; Stromal Interaction Molecule 1/genetics ; Stromal Interaction Molecule 1/metabolism
    Chemical Substances Calcium Channels ; Stromal Interaction Molecule 1 ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2021-12-07
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 2687154-3
    ISSN 2050-084X ; 2050-084X
    ISSN (online) 2050-084X
    ISSN 2050-084X
    DOI 10.7554/eLife.75174
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Bidirectional Allosteric Coupling between PIP

    Humer, Christina / Radiskovic, Tamara / Horváti, Kata / Lindinger, Sonja / Groschner, Klaus / Romanin, Christoph / Höglinger, Carmen

    International journal of molecular sciences

    2024  Volume 25, Issue 1

    Abstract: The epithelial ion channel TRPV6 plays a pivotal role in calcium homeostasis. Channel function is intricately regulated at different stages, involving the lipid phosphatidylinositol-4,5-bisphosphate ( ... ...

    Abstract The epithelial ion channel TRPV6 plays a pivotal role in calcium homeostasis. Channel function is intricately regulated at different stages, involving the lipid phosphatidylinositol-4,5-bisphosphate (PIP
    MeSH term(s) Binding Sites ; Calcium ; Cytosol ; Phosphatidylinositols/metabolism ; TRPV Cation Channels/metabolism
    Chemical Substances Calcium (SY7Q814VUP) ; Phosphatidylinositols ; TRPV Cation Channels
    Language English
    Publishing date 2024-01-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms25010618
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Highlighting the Multifaceted Role of Orai1 N-Terminal- and Loop Regions for Proper CRAC Channel Functions.

    Humer, Christina / Romanin, Christoph / Höglinger, Carmen

    Cells

    2022  Volume 11, Issue 3

    Abstract: Orai1, the ... ...

    Abstract Orai1, the Ca
    MeSH term(s) Calcium Channels/metabolism ; Calcium Release Activated Calcium Channels/metabolism ; Cell Membrane/metabolism ; Endoplasmic Reticulum/metabolism
    Chemical Substances Calcium Channels ; Calcium Release Activated Calcium Channels
    Language English
    Publishing date 2022-01-22
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells11030371
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Natural photoswitches expose STIM1 activation steps.

    Derler, Isabella / Romanin, Christoph

    Cell calcium

    2020  Volume 90, Page(s) 102240

    Abstract: STIM1, an ER-located Ca2+ sensor, activates Orai1 channels upon Ca2+-storedepletion. Prior to this, STIM1 undergoes a sequence of conformational changes, which cannot be controlled individually with high spatiotemporal resolution. Ma et al. [1] used the ... ...

    Abstract STIM1, an ER-located Ca2+ sensor, activates Orai1 channels upon Ca2+-storedepletion. Prior to this, STIM1 undergoes a sequence of conformational changes, which cannot be controlled individually with high spatiotemporal resolution. Ma et al. [1] used the power of optogenetic engineering to transfer light-sensitivity to STIM1 and precisely characterize individual STIM1 activation steps.
    MeSH term(s) Animals ; Humans ; Light ; Models, Biological ; Optogenetics ; Protein Domains ; Stromal Interaction Molecule 1/chemistry ; Stromal Interaction Molecule 1/metabolism
    Chemical Substances Stromal Interaction Molecule 1
    Language English
    Publishing date 2020-06-13
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 757687-0
    ISSN 1532-1991 ; 0143-4160
    ISSN (online) 1532-1991
    ISSN 0143-4160
    DOI 10.1016/j.ceca.2020.102240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Activation mechanisms and structural dynamics of STIM proteins.

    Sallinger, Matthias / Grabmayr, Herwig / Humer, Christina / Bonhenry, Daniel / Romanin, Christoph / Schindl, Rainer / Derler, Isabella

    The Journal of physiology

    2023  Volume 602, Issue 8, Page(s) 1475–1507

    Abstract: The family of stromal interaction molecules (STIM) includes two widely expressed single-pass endoplasmic reticulum (ER) transmembrane proteins and additional splice variants that act as precise ER-luminal ... ...

    Abstract The family of stromal interaction molecules (STIM) includes two widely expressed single-pass endoplasmic reticulum (ER) transmembrane proteins and additional splice variants that act as precise ER-luminal Ca
    MeSH term(s) Calcium Signaling/physiology ; Stromal Interaction Molecules/metabolism ; ORAI1 Protein ; Stromal Interaction Molecule 1/metabolism ; Membrane Proteins/metabolism ; Calcium Release Activated Calcium Channels ; Calcium/metabolism
    Chemical Substances Stromal Interaction Molecules ; ORAI1 Protein ; Stromal Interaction Molecule 1 ; Membrane Proteins ; Calcium Release Activated Calcium Channels ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2023-02-02
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 3115-x
    ISSN 1469-7793 ; 0022-3751
    ISSN (online) 1469-7793
    ISSN 0022-3751
    DOI 10.1113/JP283828
    Database MEDical Literature Analysis and Retrieval System OnLINE

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