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  1. Book ; Online: Chapter Rappresentazioni vertiginose. Tre esempi: Perec, Lequeu, Douat

    Romano, Felice

    (diségno)

    2022  

    Series title diségno
    Keywords Semiotics / semiology ; History ; Impact of science & technology on society ; Discipline of representation, History, Semiotics, Science, Technology
    Language Italian
    Size 1 Online-Ressource
    Publisher FrancoAngeli
    Publishing place Milan
    Document type Book ; Online
    Note Italian ; English
    HBZ-ID HT030380139
    ISBN 9788835141938 ; 8835141931
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Computational pulmonary edema: A microvascular model of alveolar capillary and interstitial flow.

    Grotberg, James B / Romanò, Francesco

    APL bioengineering

    2023  Volume 7, Issue 3, Page(s) 36101

    Abstract: We present a microvascular model of fluid transport in the alveolar septa related to pulmonary edema. It consists of a two-dimensional capillary sheet coursing by several alveoli. The alveolar epithelial membrane runs parallel to the capillary ... ...

    Abstract We present a microvascular model of fluid transport in the alveolar septa related to pulmonary edema. It consists of a two-dimensional capillary sheet coursing by several alveoli. The alveolar epithelial membrane runs parallel to the capillary endothelial membrane with an interstitial layer in between, making one long septal tract. A coupled system of equations uses lubrication theory for the capillary blood, Darcy flow for the porous media of the interstitium, a passive alveolus, and the Starling equation at both membranes. Case examples include normal physiology, cardiogenic pulmonary edema, acute respiratory distress syndrome (ARDS), hypoalbuminemia, and effects of PEEP. COVID-19 has dramatically increased ARDS in the world population, raising the urgency for such a model to create an analytical framework. Under normal conditions fluid exits the alveolus, crosses the interstitium, and enters the capillary. For edema, this crossflow is reversed with fluid leaving the capillary and entering the alveolus. Because both the interstitial and capillary pressures decrease downstream, the reversal can occur within a single septal tract, with edema upstream and clearance downstream. Clinically useful solution forms are provided allowing calculation of interstitial fluid pressure, crossflows, and critical capillary pressures. Overall, the interstitial pressures are found to be significantly more positive than values used in the traditional physiological literature. That creates steep gradients near the upstream and downstream end outlets, driving significant flows toward the distant lymphatics. This new physiological flow provides an explanation to the puzzle, noted since 1896, of how pulmonary lymphatics can function so far from the alveoli: the interstitium is self-clearing.
    Language English
    Publishing date 2023-07-05
    Publishing country United States
    Document type Journal Article
    ISSN 2473-2877
    ISSN (online) 2473-2877
    DOI 10.1063/5.0158324
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Retraction: "Computational pulmonary edema: A microvascular model of alveolar capillary and interstitial flow" [APL Bioeng.

    Grotberg, James B / Romanò, Francesco

    APL bioengineering

    2023  Volume 7, Issue 2, Page(s) 29902

    Abstract: This retracts the article DOI: 10.1063/5.0109107.]. ...

    Abstract [This retracts the article DOI: 10.1063/5.0109107.].
    Language English
    Publishing date 2023-06-07
    Publishing country United States
    Document type Retraction of Publication
    ISSN 2473-2877
    ISSN (online) 2473-2877
    DOI 10.1063/5.0158314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Recent developments in absolute dosimetry for FLASH radiotherapy.

    Subiel, Anna / Romano, Francesco

    The British journal of radiology

    2023  Volume 96, Issue 1148, Page(s) 20220560

    Abstract: Ultra-high dose-rate (UHDR) irradiations, known as FLASH radiotherapy (RT), rely on delivery of therapeutic doses at instantaneous dose-rates several orders of magnitude higher than those currently used in conventional radiotherapy. It has been shown ... ...

    Abstract Ultra-high dose-rate (UHDR) irradiations, known as FLASH radiotherapy (RT), rely on delivery of therapeutic doses at instantaneous dose-rates several orders of magnitude higher than those currently used in conventional radiotherapy. It has been shown that such an extremely short delivery of radiation leads to remarkable reduction of normal tissue toxicity with respect to conventional dose-rate RT. However, dosimetry at UHDRs is complicated and it is essential to understand the effects that will influence detector response. To date, FLASH RT research has been focused on finding pragmatic solutions that allow the use of UHDR beams in the research setting, but there has been limited focus on absolute dosimetry utilizing primary and secondary standard devices. However, very recently, the data on existing standard dosimeters and novel solutions which could serve as secondary standard devices in UHDR dosimetry started emerging. This review provides an overview of the studies that have been conducted employing calorimeters and innovative solutions utilizing ionization chambers.
    MeSH term(s) Humans ; Radiometry/methods ; Radiotherapy Dosage ; Radiotherapy/methods
    Language English
    Publishing date 2023-06-11
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2982-8
    ISSN 1748-880X ; 0007-1285
    ISSN (online) 1748-880X
    ISSN 0007-1285
    DOI 10.1259/bjr.20220560
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.11: Show issues Location:
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  5. Article ; Online: Efficacy of a single dose of nitazoxanide in dogs naturally infected with Giardia duodenalis.

    Romano, Felipe / Lallo, Maria Anete

    Research in veterinary science

    2023  Volume 159, Page(s) 252–256

    Abstract: Giardia duodenalis is a protozoan parasite that infects many mammals, including dogs and cats. This waterborne and foodborne zoonosis is a major problem in one health. Treatment can be challenging because of long regimens and drug resistance. The ... ...

    Abstract Giardia duodenalis is a protozoan parasite that infects many mammals, including dogs and cats. This waterborne and foodborne zoonosis is a major problem in one health. Treatment can be challenging because of long regimens and drug resistance. The objective of this study was to evaluate the efficacy of single-dose nitazoxanide (NTZ) for dogs naturally infected by Giardia duodenalis. Although widely used in humans, pharmacological safety is incipient, since the approval of the safe use of nitaxozanide for dogs is not a consensus in the world. Fifty dogs diagnosed with G. duodenalis by zinc sulfate flotation technique (Faust method) and cysts detection by light microscopy. Half of the animals received a dose of 50 mg/kg of NTZ and the other half received 3 doses of 50 mg/kg of fenbendazole (FBZ), both orally. One week after treatment, new fecal exams were done to prove the effectiveness. Of the animals treated with NTZ, 84% were negative for the protozoan, while 76% of the animals treated with FBZ were negative, no significant difference was identified. Side effects such as vomiting and hyporexia were manageable in NTZ treatment and no changes in laboratory tests showed hepatic or renal impairment. We conclude that the use of NTZ in a single dose of 50 mg/kg is effective for canine giardiasis, constituting an option to be considered for dogs with relapses, poor response to conventional drugs and to facilitate administration regimens.
    MeSH term(s) Humans ; Animals ; Dogs ; Cats ; Giardia lamblia ; Cat Diseases/diagnosis ; Dog Diseases/diagnosis ; Giardiasis/drug therapy ; Giardiasis/veterinary ; Feces/parasitology ; Mammals
    Chemical Substances nitazoxanide (SOA12P041N)
    Language English
    Publishing date 2023-04-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 840961-4
    ISSN 1532-2661 ; 0034-5288
    ISSN (online) 1532-2661
    ISSN 0034-5288
    DOI 10.1016/j.rvsc.2023.04.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 673: Show issues Location:
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  6. Article ; Online: Efficacy of a single dose of nitazoxanide in dogs naturally infected with Giardia duodenalis

    Romano, Felipe / Lallo, Maria Anete

    Research in Veterinary Science. 2023 June, v. 159 p.252-256

    2023  

    Abstract: Giardia duodenalis is a protozoan parasite that infects many mammals, including dogs and cats. This waterborne and foodborne zoonosis is a major problem in one health. Treatment can be challenging because of long regimens and drug resistance. The ... ...

    Abstract Giardia duodenalis is a protozoan parasite that infects many mammals, including dogs and cats. This waterborne and foodborne zoonosis is a major problem in one health. Treatment can be challenging because of long regimens and drug resistance. The objective of this study was to evaluate the efficacy of single-dose nitazoxanide (NTZ) for dogs naturally infected by Giardia duodenalis. Although widely used in humans, pharmacological safety is incipient, since the approval of the safe use of nitaxozanide for dogs is not a consensus in the world. Fifty dogs diagnosed with G. duodenalis by zinc sulfate flotation technique (Faust method) and cysts detection by light microscopy. Half of the animals received a dose of 50 mg/kg of NTZ and the other half received 3 doses of 50 mg/kg of fenbendazole (FBZ), both orally. One week after treatment, new fecal exams were done to prove the effectiveness. Of the animals treated with NTZ, 84% were negative for the protozoan, while 76% of the animals treated with FBZ were negative, no significant difference was identified. Side effects such as vomiting and hyporexia were manageable in NTZ treatment and no changes in laboratory tests showed hepatic or renal impairment. We conclude that the use of NTZ in a single dose of 50 mg/kg is effective for canine giardiasis, constituting an option to be considered for dogs with relapses, poor response to conventional drugs and to facilitate administration regimens.
    Keywords Giardia lamblia ; dogs ; drug resistance ; fenbendazole ; giardiasis ; light microscopy ; parasites ; research ; veterinary medicine ; zinc sulfate ; zoonoses ; Canine giardiasis ; Giardia duodenalis ; Nitazoxanide ; Treatment
    Language English
    Dates of publication 2023-06
    Size p. 252-256.
    Publishing place Elsevier Ltd
    Document type Article ; Online
    ZDB-ID 840961-4
    ISSN 1532-2661 ; 0034-5288
    ISSN (online) 1532-2661
    ISSN 0034-5288
    DOI 10.1016/j.rvsc.2023.04.022
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 2292: Show issues

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  7. Article ; Online: Impairment of salivary function in juvenile idiopathic oligoarticular arthritis is a sign of early onset disease.

    Defabianis, P / Carli, E / Garofalo, F / Romano, F

    European journal of paediatric dentistry

    2022  Volume 23, Issue 3, Page(s) 213–216

    Abstract: Aim: Recent evidences of the presence of reduced stimulated salivary flow rate and altered saliva composition in oligoarticular juvenile idiopathic arthritis (o-JIA) suggest a specific damage to the salivary glands. The aim of this cross-sectional study ...

    Abstract Aim: Recent evidences of the presence of reduced stimulated salivary flow rate and altered saliva composition in oligoarticular juvenile idiopathic arthritis (o-JIA) suggest a specific damage to the salivary glands. The aim of this cross-sectional study was to investigate whether reduced salivary flow rate could be related to age and gender at disease onset in o-JIA.
    Methods: A total of 57 Caucasian patients (41 females and 16 males) aged 5 to 16 years affected by o-JIA were consecutively enrolled in the study. Information on medication intake, dietary and oral hygiene habits were gathered through a standardised questionnaire. All patients underwent oral and sialometry examination.
    Conclusion: Early onset disease would seem to be associated with salivary glands impairment. Regular dental and salivary gland function assessments may be highly recommended in o-JIA patients considering that saliva collection is a non-invasive and inexpensive procedure.
    MeSH term(s) Arthritis, Juvenile/complications ; Cross-Sectional Studies ; Female ; Humans ; Male ; Oral Hygiene ; Saliva/metabolism ; Salivary Glands/metabolism ; Salivation
    Language English
    Publishing date 2022-09-29
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2035588-9
    ISSN 2035-648X ; 1591-996X
    ISSN (online) 2035-648X
    ISSN 1591-996X
    DOI 10.23804/ejpd.2022.23.03.08
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5002: Show issues Location:
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  8. Article ; Online: Expanded field: filling the gap between macula and widefield.

    Romano, Francesco / Ding, Xinyi / Miller, John B

    Eye (London, England)

    2024  

    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-024-02978-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 3010: Show issues Location:
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  9. Article ; Online: An Estimate of the Economic Impact of COVID-19 on Australia

    Romano, Flavio

    SSRN Electronic Journal ; ISSN 1556-5068

    2020  

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.2139/ssrn.3581382
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Could COVID-19 Lead to Another Great Depression? Evidence from the USA and Australia

    Romano, Flavio

    SSRN Electronic Journal ; ISSN 1556-5068

    2020  

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.2139/ssrn.3609548
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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