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  1. Article ; Online: A new case of HTLV1 with rapidly progressive longitudinally extensive transverse myelitis: the importance of early diagnosis in therapeutic response.

    Romero Del Rincón, Celia / Pérez, Javier B / Barbosa Del Olmo, Antonio / Bautista Hernandez, Azucena / Sánchez-Rodriguez, Carmen / Quintas, Sonia

    Acta neurologica Belgica

    2023  

    Language English
    Publishing date 2023-05-26
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 127315-2
    ISSN 2240-2993 ; 0300-9009
    ISSN (online) 2240-2993
    ISSN 0300-9009
    DOI 10.1007/s13760-023-02289-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui I Zs.57: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Proprioceptive Stimuli as a New Type of Trigger for Epilepsy in Stiff Person Syndrome.

    Panos Basterra, Paula / Nombela, Florentino / Iriarte, Pablo / Romero Del Rincon, Celia / Alonso Maroto, Jaime / Quintas, Sonia

    Neurology

    2022  Volume 99, Issue 16, Page(s) 711–712

    MeSH term(s) Humans ; Stiff-Person Syndrome/complications ; Epilepsy/complications ; Autoantibodies
    Chemical Substances Autoantibodies
    Language English
    Publishing date 2022-10-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000201196
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui II Zs.153: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 18: Show issues
    Zs.MO 374: Show issues

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  3. Article ; Online: RE-START: Exploring the effectiveness of anti-calcitonin gene-related peptide resumption after discontinuation in migraine.

    Romero Del Rincón, Celia / Gonzalez-Martinez, Alicia / Quintas, Sonia / García-Azorín, David / Fernández Lázaro, Iris / Guerrero-Peral, Angel Luis / Gonzalez Osorio, Yesica / Santos-Lasaosa, Sonia / González Oria, Carmen / Sánchez Rodríguez, Norberto / Iglesias Díez, Fernando / Echavarría Íñiguez, Ana / Gil Luque, Sendoa / Huerta-Villanueva, Mariano / Campoy Díaz, Sergio / Muñoz-Vendrell, Albert / Lozano Ros, Alberto / Sánchez-Soblechero, Antonio / Velasco Juanes, Fernando /
    Kortazar-Zubizarreta, Izaro / Echeverría, Amaya / Rodríguez-Vico, Jaime / Jaimes Sánchez, Alex / Gómez García, Andrea / Morollón Sánchez-Mateos, Noemí / Belvis, Robert / Navarro Pérez, María Pilar / García-Moncó, Juan Carlos / Álvarez Escudero, María Rocío / Montes, Nuria / Gago-Veiga, Ana Beatriz

    European journal of neurology

    2024  Volume 31, Issue 4, Page(s) e16203

    Abstract: Background and purpose: According to the latest European guidelines, discontinuation of monoclonal antibodies against calcitonin gene-related peptide (anti-CGRP MAb) may be considered after 12-18 months of treatment. However, some patients may worsen ... ...

    Abstract Background and purpose: According to the latest European guidelines, discontinuation of monoclonal antibodies against calcitonin gene-related peptide (anti-CGRP MAb) may be considered after 12-18 months of treatment. However, some patients may worsen after discontinuation. In this study, we assessed the response following treatment resumption.
    Methods: This was a prospective study conducted in 14 Headache Units in Spain. We included patients with response to anti-CGRP MAb with clinical worsening after withdrawal and resumption of treatment. Numbers of monthly migraine days (MMD) and monthly headache days (MHD) were obtained at four time points: before starting anti-CGRP MAb (T-baseline); last month of first treatment period (T-suspension); month of restart due to worsening (T-worsening); and 3 months after resumption (T-reintroduction). The response rate to resumption was calculated. Possible differences among periods were analysed according to MMD and MHD.
    Results: A total of 360 patients, 82% women, with a median (interquartile range [IQR]) age at migraine onset of 18 (12) years. The median (IQR) MHD at T-baseline was 20 (13) and MMD was 5 (6); at T-suspension, the median (IQR) MHD was 5 (6) and MMD was 4 (5); at T-worsening, the median (IQR) MHD was 16 (13) and MMD was 12 (6); and at T-reintroduction, the median (IQR) MHD was 8 (8) and MHD was 5 (5). In the second period of treatment, a 50% response rate was achieved by 57.4% of patients in MHD and 65.8% in MMD. Multivariate models showed significant differences in MHD between the third month after reintroduction and last month before suspension of first treatment period (p < 0.001).
    Conclusion: The results suggest that anti-CGRP MAb therapy is effective after reintroduction. However, 3 months after resumption, one third of the sample reached the same improvement as after the first treatment period.
    MeSH term(s) Humans ; Female ; Adolescent ; Male ; Calcitonin Gene-Related Peptide ; Prospective Studies ; Migraine Disorders ; Headache ; Antibodies, Monoclonal
    Chemical Substances Calcitonin Gene-Related Peptide (JHB2QIZ69Z) ; Antibodies, Monoclonal
    Language English
    Publishing date 2024-01-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 1280785-0
    ISSN 1468-1331 ; 1351-5101 ; 1471-0552
    ISSN (online) 1468-1331
    ISSN 1351-5101 ; 1471-0552
    DOI 10.1111/ene.16203
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4738: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 592: Show issues

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