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Article ; Online: Optimization of table tennis target detection algorithm guided by multi-scale feature fusion of deep learning.

Rong, Zhang

2024 Volume 14, Issue 1, Page(s) 1401

Abstract: This paper aims to propose a table tennis target detection (TD) method based on deep learning (DL) and multi-scale feature fusion (MFF) to improve the detection accuracy of the ball in table tennis competition, optimize the training process of athletes, ... ...

Abstract	This paper aims to propose a table tennis target detection (TD) method based on deep learning (DL) and multi-scale feature fusion (MFF) to improve the detection accuracy of the ball in table tennis competition, optimize the training process of athletes, and improve the technical level. In this paper, DL technology is used to improve the accuracy of table tennis TD through MFF guidance. Initially, based on the FAST Region-based Convolutional Neural Network (FAST R-CNN), the TD is carried out in the table tennis match. Then, through the method of MFF guidance, different levels of feature information are fused, which improves the accuracy of TD. Through the experimental verification on the test set, it is found that the mean Average Precision (mAP) value of the target detection algorithm (TDA) proposed here reaches 87.3%, which is obviously superior to other TDAs and has higher robustness. The DL TDA combined with the proposed MFF can be applied to various detection fields and can help the application of TD in real life.
Language	English
Publishing date	2024-01-16
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-51865-3
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Article ; Online: Decoding complex order in reticular frameworks.

Yaghi, Omar M / Rong, Zichao

Science (New York, N.Y.)

2023 Volume 379, Issue 6630, Page(s) 330–331

Abstract: Periodicity and aperiodicity coexist in a nonchaotic, information-rich crystal structure. ...

Abstract	Periodicity and aperiodicity coexist in a nonchaotic, information-rich crystal structure.
Language	English
Publishing date	2023-01-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	128410-1
ISSN	1095-9203 ; 0036-8075
ISSN (online)	1095-9203
ISSN	0036-8075
DOI	10.1126/science.adf0261
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Zs.A 27: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article: [Review and prospects of international clinical research in critical care medicine in 2023].

Rong, Ziqi / Lu, Pengyu / Huang, Wei

Zhonghua wei zhong bing ji jiu yi xue

2024 Volume 36, Issue 2, Page(s) 113–117

Abstract: The main clinical research advances of critical care in 2023 includes: new trials of Chinese herbal medicine, hydroxocobalamin (vitamin B12), methylene blue as well glucocorticoids have shown the potential to improve outcomes of patients with sepsis and ... ...

Abstract	The main clinical research advances of critical care in 2023 includes: new trials of Chinese herbal medicine, hydroxocobalamin (vitamin B12), methylene blue as well glucocorticoids have shown the potential to improve outcomes of patients with sepsis and septic shock; international committees launched new global definition and managing recommendations for acute respiratory distress syndrome (ARDS). Besides, a cluster of new evidences has emerged in many aspects as following: fluid control strategy in sepsis (restrictive/liberative), antibiotic infusion strategy (continuous/intermittent), oxygen-saturation targets for mechanical ventilation (conservative/liberative), blood pressure targets after resuscitation from out-of-hospital cardiac arrest (hypotension/hypertension), blood pressure targets after successful stroke thrombectomy (intensive/conventional), and nutritional support strategies (low protein-calories/conventional protein-calories, fasting/persistent feeding before extubation). Thus, given above progress, carrying out high -quality domestic multi-center clinical registration researches, constructing shareable standardized databases, as well raising public awareness of sepsis, should be the essential steps to improve our level of intensive care medicine.
MeSH term(s)	Humans ; Critical Care ; Sepsis/therapy ; Shock, Septic/therapy ; Airway Extubation ; Blood Pressure
Language	Chinese
Publishing date	2024-03-05
Publishing country	China
Document type	English Abstract ; Journal Article
ISSN	2095-4352
ISSN	2095-4352
DOI	10.3760/cma.j.cn121430-20240111-00032
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Article ; Online: Alkaline earth modified activated carbon supported Cu catalysts with enhanced selectivity in the hydrogenation of dimethyl oxalate to methyl glycolate.

Rong, Zanji / Shen, Weihua / Fang, Yunjin

RSC advances

2024 Volume 14, Issue 17, Page(s) 11849–11861

Abstract: In this work, the effect of alkaline earth metal modification on the catalytic performance of activated carbon supported Cu was investigated. The experimental results showed that the introduction of Ca and Sr improved the selectivity of methyl glycolate ( ...

Abstract	In this work, the effect of alkaline earth metal modification on the catalytic performance of activated carbon supported Cu was investigated. The experimental results showed that the introduction of Ca and Sr improved the selectivity of methyl glycolate (MG) during hydrogenation of dimethyl oxalate (DMO) in gas phase. The optimal loading amount of Ca was 0.1 wt%, and under the optimal conditions (temperature 240 °C, pressure 2 MPa, hydrogen-ester ratio of 80, feedstock 15% DMO methanol solution, and WLHSV
Language	English
Publishing date	2024-04-12
Publishing country	England
Document type	Journal Article
ISSN	2046-2069
ISSN (online)	2046-2069
DOI	10.1039/d4ra01049c
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Article ; Online: Decarboxylative Sulfonylation of Carboxylic Acids under Mild Photomediated Iron Catalysis.

Dong, Yuanqi / Xiong, Ni / Rong, Zhouting / Zeng, Rong

Organic letters

2024 Volume 26, Issue 12, Page(s) 2381–2386

Abstract: Organic sulfones are an important class of chemical compounds widely used in many research fields. The direct decarboxylative sulfonylation of carboxylic acids is attractive but challenging, particularly when iron is used as a metal catalyst. Herein, we ... ...

Abstract	Organic sulfones are an important class of chemical compounds widely used in many research fields. The direct decarboxylative sulfonylation of carboxylic acids is attractive but challenging, particularly when iron is used as a metal catalyst. Herein, we describe a photoinduced iron-catalytic method for the synthesis of sulfones directly using carboxylic acids via a radical-based decarboxylation. This protocol is mild, highly efficient, and easy-to-operate. A broad scope of carboxylic acids and carbon electrophiles could be well tolerated. A mechanism involving the iron-catalyzed decarboxylation, radical transfer, single-electron reduction, and nucleophilic attack is proposed.
Language	English
Publishing date	2024-03-15
Publishing country	United States
Document type	Journal Article
ISSN	1523-7052
ISSN (online)	1523-7052
DOI	10.1021/acs.orglett.4c00410
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Article ; Online: The cross talk of ubiquitination and chemotherapy tolerance in colorectal cancer.

Rong, Ze / Zheng, Kaifeng / Chen, Jun / Jin, Xiaofeng

Journal of cancer research and clinical oncology

2024 Volume 150, Issue 3, Page(s) 154

Abstract: Ubiquitination, a highly adaptable post-translational modification, plays a pivotal role in maintaining cellular protein homeostasis, encompassing cancer chemoresistance-associated proteins. Recent findings have indicated a potential correlation between ... ...

Abstract	Ubiquitination, a highly adaptable post-translational modification, plays a pivotal role in maintaining cellular protein homeostasis, encompassing cancer chemoresistance-associated proteins. Recent findings have indicated a potential correlation between perturbations in the ubiquitination process and the emergence of drug resistance in CRC cancer. Consequently, numerous studies have spurred the advancement of compounds specifically designed to target ubiquitinates, offering promising prospects for cancer therapy. In this review, we highlight the role of ubiquitination enzymes associated with chemoresistance to chemotherapy via the Wnt/β-catenin signaling pathway, epithelial-mesenchymal transition (EMT), and cell cycle perturbation. In addition, we summarize the application and role of small compounds that target ubiquitination enzymes for CRC treatment, along with the significance of targeting ubiquitination enzymes as potential cancer therapies.
MeSH term(s)	Humans ; Cell Line, Tumor ; Colorectal Neoplasms/genetics ; beta Catenin/metabolism ; Ubiquitination ; Wnt Signaling Pathway ; Epithelial-Mesenchymal Transition ; Gene Expression Regulation, Neoplastic ; Cell Proliferation
Chemical Substances	beta Catenin
Language	English
Publishing date	2024-03-23
Publishing country	Germany
Document type	Review ; Journal Article
ZDB-ID	134792-5
ISSN	1432-1335 ; 0171-5216 ; 0084-5353 ; 0943-9382
ISSN (online)	1432-1335
ISSN	0171-5216 ; 0084-5353 ; 0943-9382
DOI	10.1007/s00432-024-05659-9
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Article ; Online: Biodegradation of low-density polyethylene film by two bacteria isolated from plastic debris in coastal beach.

Rong, Zhen / Xu, Xue-Wei / Wu, Yue-Hong

Ecotoxicology and environmental safety

2024 Volume 278, Page(s) 116445

Abstract: Low-density polyethylene (LDPE) conduces massive environmental accumulation due to its high production and recalcitrance to environment. In this study, We successfully enriched and isolated two strains, Nitratireductor sp. Z-1 and Gordonia sp. Z-2, from ... ...

Abstract	Low-density polyethylene (LDPE) conduces massive environmental accumulation due to its high production and recalcitrance to environment. In this study, We successfully enriched and isolated two strains, Nitratireductor sp. Z-1 and Gordonia sp. Z-2, from coastal plastic debris capable of degrading LDPE film. After a 30-day incubation at 30 ℃, strains Z-1 and Z-2 decreased the weight of branched-LDPE (BLDPE) film by 2.59 % and 10.27 % respectively. Furthermore, high temperature gel permeation chromatography (HT-GPC) analysis revealed molecular weight reductions of 7.69 % (Z-1) and 23.22 % (Z-2) in the BLDPE film. Scanning electron microscope (SEM) image showed the presence of microbial colonization and perforations on the film's surface. Fourier transform infrared spectroscopy (FTIR) analysis indicated novel functional groups, such as carbonyl and carbon-carbon double bonds in LDPE films. During LDPE degradation, both strains produced extracellular reactive oxygen species (ROS). GC-MS analysis revealed the degradation products included short-chain alkanes, alkanols, fatty acids, and esters. Genomic analysis identified numerous extracellular enzymes potentially involved in LDPE chain scission. A model was proposed suggesting a coordinated role between ROS and extracellular enzymes in the biodegradation of LDPE. This indicates strains Z-1 and Z-2 can degrade LDPE, providing a basis for deeper exploration of biodegradation mechanisms.
Language	English
Publishing date	2024-05-10
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	436536-7
ISSN	1090-2414 ; 0147-6513
ISSN (online)	1090-2414
ISSN	0147-6513
DOI	10.1016/j.ecoenv.2024.116445
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Zs.A 1418: Show issues

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Article ; Online: Upgulation of lncRNA GASL1 inhibits atherosclerosis by regulating miR-106a/LKB1 axis.

Rui, Xueqi / Wu, Xinning / Rong, Zheyi / Wang, Zipeng

BMC cardiovascular disorders

2023 Volume 23, Issue 1, Page(s) 11

Abstract: Background: Atherosclerosis (AS) is a common frequently-occurring disease in the clinic and a serious threat to human health. This research aimed to explore the value between GASL1 and AS.: Methods: The expression and values of GASL1 in AS patients ... ...

Abstract	Background: Atherosclerosis (AS) is a common frequently-occurring disease in the clinic and a serious threat to human health. This research aimed to explore the value between GASL1 and AS. Methods: The expression and values of GASL1 in AS patients were revealed by qRT-PCR and ROC curve. The HUVEC cells were induced by ox-LDL to construct in-vitro models. Cell viability was detected by MTT assay, and apoptosis was detected by flow cytometry. The inflammatory situation was reflected by the ELISA assay. Double luciferase reporter gene assay verified the regulatory relationship between GASL1 and miR-106a, miR-106a and LKB1. Results: The levels of GASL1 was lower in AS group than those in control group. The value of GASL1 in predicting AS patients was also tested by the ROC curve. After HUVEC cells were induced by ox-LDL, the levels of GASL1 and LKB1 decreased significantly, while the level of miR-106a increased significantly. Upregulation of LKB1 reversed the effect of upregulation of GASL1 on viability, apoptosis, and inflammation of HUVEC cells induced by ox-LDL. Conclusion: Overexpression of GASL1 might suppress ox-LDL-induced HUVEC cell viability, apoptosis, and inflammation by regulating miR-106a/LKB1 axis.
MeSH term(s)	Humans ; Apoptosis ; Atherosclerosis/genetics ; Atherosclerosis/prevention & control ; Atherosclerosis/metabolism ; Cell Proliferation ; Human Umbilical Vein Endothelial Cells/metabolism ; Inflammation ; Lipoproteins, LDL/pharmacology ; MicroRNAs/genetics ; MicroRNAs/metabolism ; RNA, Long Noncoding/genetics ; RNA, Long Noncoding/metabolism ; AMP-Activated Protein Kinase Kinases/genetics ; AMP-Activated Protein Kinase Kinases/metabolism
Chemical Substances	Lipoproteins, LDL ; MicroRNAs ; RNA, Long Noncoding ; long non-coding RNA GASL1, human ; MIRN106 microRNA, human ; STK11 protein, human (EC 2.7.11.1) ; AMP-Activated Protein Kinase Kinases (EC 2.7.11.3)
Language	English
Publishing date	2023-01-10
Publishing country	England
Document type	Journal Article
ZDB-ID	2059859-2
ISSN	1471-2261 ; 1471-2261
ISSN (online)	1471-2261
ISSN	1471-2261
DOI	10.1186/s12872-023-03038-9
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Article ; Online: Mitigation of Hearing Damage With Liraglutide Treatment in Chinchillas After Repeated Blast Exposures at Mild-TBI.

Jiang, Shangyuan / Sanders, Sarah / Gan, Rong Z

Military medicine

2023 Volume 188, Issue Suppl 6, Page(s) 553–560

Abstract: Introduction: Although hearing protection devices (HPDs) have been widely used during training and combat, over one million veterans experience service-connected hearing loss. Hearing damage has been reported to be associated with blast-induced mild ... ...

Abstract	Introduction: Although hearing protection devices (HPDs) have been widely used during training and combat, over one million veterans experience service-connected hearing loss. Hearing damage has been reported to be associated with blast-induced mild traumatic brain injury (mTBI) and there is a lack of understanding and treatment. Liraglutide is a glucagon-like peptide-1 receptor agonist and a potential treatment for TBI-induced memory deficits. This study aims to investigate the function of the liraglutide to prevent damage and facilitate hearing restoration in chinchillas exposed to multiple high-intensity, mTBI-level blasts. Materials and methods: Chinchillas were divided into three treatment groups: blast control, pre-blast drug treatment, and post-blast drug treatment. On day 1, the chinchilla ears were protected by HPDs and exposed to three blasts with peak pressure levels of 15-25 psi. The auditory brainstem response (ABR), distortion product otoacoustic emission (DPOAE), and middle latency response (MLR) were recorded pre- and post-blast on day 1 and on days 4, 7, 14, and 28. Results: Substantial acute damage was observed and progressively recovered in chinchillas after the blast exposures. The pre-blast treatment group exhibited the lowest elevation of the ABR threshold and reduction of the wave I amplitude on day 1 after blasts. The liraglutide treatment insignificantly facilitated the recovery of the DPOAE levels and ABR thresholds on days 14 and 28. The pre-blast treatment chinchillas showed reduced MLR amplitudes on days 4 and 7. Conclusions: This study indicated that the pre-blast liraglutide administration provided damage protection against blasts in addition to the HPDs. Current evidence suggests that the effect of liraglutide is more prominent in the early phase of the experiment.
MeSH term(s)	Humans ; Animals ; Chinchilla ; Liraglutide/pharmacology ; Liraglutide/therapeutic use ; Hearing ; Otoacoustic Emissions, Spontaneous ; Brain Concussion
Chemical Substances	Liraglutide (839I73S42A)
Language	English
Publishing date	2023-11-01
Publishing country	England
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	391061-1
ISSN	1930-613X ; 0026-4075
ISSN (online)	1930-613X
ISSN	0026-4075
DOI	10.1093/milmed/usad235
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Article ; Online: Real-time measurement of stapes motion and intracochlear pressure during blast exposure.

Bien, Alexander G / Jiang, Shangyuan / Gan, Rong Z

Hearing research

2023 Volume 429, Page(s) 108702

Abstract: Blast-induced auditory injury is primarily caused by exposure to an overwhelming amount of energy transmitted into the external auditory canal, the middle ear, and then the cochlea. Quantification of this energy requires real-time measurement of stapes ... ...

Abstract	Blast-induced auditory injury is primarily caused by exposure to an overwhelming amount of energy transmitted into the external auditory canal, the middle ear, and then the cochlea. Quantification of this energy requires real-time measurement of stapes footplate (SFP) motion and intracochlear pressure in the scala vestibuli (Psv). To date, SFP and Psv have not been measured simultaneously during blast exposure, but a dual-laser experimental approach for detecting the movement of the SFP was reported by Jiang et al. (2021). In this study, we have incorporated the measurement of Psv with SFP motion and developed a novel approach to quantitatively measure the energy flux entering the cochlea during blast exposure. Five fresh human cadaveric temporal bones (TBs) were used in this study. A mastoidectomy and facial recess approach were performed to identify the SFP, followed by a cochleostomy into the scala vestibuli (SV). The TB was mounted to the "head block", a fixture to simulate a real human skull, with two pressure sensors - one inserted into the SV (Psv) and another in the ear canal near the tympanic membrane (P1). The TB was exposed to the blast overpressure (P0) around 4 psi or 28 kPa. Two laser Doppler vibrometers (LDVs) were used to measure the movements of the SFP and TB (as a reference). The LDVs, P1, and Psv signals were triggered by P0 and recorded simultaneously. The results include peak values for Psv of 100.8 ± 51.6 kPa (mean ± SD) and for SFP displacement of 72.6 ± 56.4 μm, which are consistent with published experimental results and finite element modeling data. Most of the P0 input energy flux into the cochlea occurred within 2 ms and resulted in 10-70 μJ total energy entering the cochlea. Although the middle ear pressure gain was close to that measured under acoustic stimulus conditions, the nonlinear behavior of the middle ear was observed from the elevated cochlear input impedance. For the first time, SFP movement and intracochlear pressure Psv have been successfully measured simultaneously during blast exposure. This study provides a new methodology and experimental data for determining the energy flux entering the cochlea during a blast, which serves as an injury index for quantifying blast-induced auditory damage.
MeSH term(s)	Humans ; Stapes ; Sound ; Cochlea/surgery ; Scala Vestibuli ; Ear, Middle
Language	English
Publishing date	2023-01-13
Publishing country	Netherlands
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	282629-x
ISSN	1878-5891 ; 0378-5955
ISSN (online)	1878-5891
ISSN	0378-5955
DOI	10.1016/j.heares.2023.108702
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