LIVIVO - Search results -

Search results

Result 1 - 10 of total 70

Search options

Article ; Online: That's the Way You Do It.

Roop, R Martin

2019 Volume 201, Issue 12

Abstract: About one-third of the proteins encoded by the bacterial genomes that have been sequenced to date are proteins of "unknown function." Studies aimed at defining the biological functions of these proteins represent an important frontier in prokaryotic ... ...

Abstract	About one-third of the proteins encoded by the bacterial genomes that have been sequenced to date are proteins of "unknown function." Studies aimed at defining the biological functions of these proteins represent an important frontier in prokaryotic biology. The study presented by J. Herrou et al. (J Bacteriol 201:e00134-19, 2019) in this issue of the
MeSH term(s)	Brucella ; Periplasm ; Periplasmic Proteins ; Virulence ; Virulence Factors
Chemical Substances	Periplasmic Proteins ; Virulence Factors
Language	English
Publishing date	2019-05-22
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	2968-3
ISSN	1098-5530 ; 0021-9193
ISSN (online)	1098-5530
ISSN	0021-9193
DOI	10.1128/JB.00216-19
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ud II Zs.50: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Comparison of CcrM-dependent methylation in

Campbell, Maxwell / Barton, Ian Scott / Roop, R Martin / Chien, Peter

bioRxiv : the preprint server for biology

2024

Abstract: Bacteria rely on DNA methylation for restriction-modification systems and epigenetic control of gene expression. Here, we use direct detection of methylated bases by nanopore sequencing to monitor global DNA methylation in Alphaproteobacteria, where use ... ...

Abstract	Bacteria rely on DNA methylation for restriction-modification systems and epigenetic control of gene expression. Here, we use direct detection of methylated bases by nanopore sequencing to monitor global DNA methylation in Alphaproteobacteria, where use of this technique has not yet been reported. One representative of this order,
Language	English
Publishing date	2024-03-02
Publishing country	United States
Document type	Preprint
DOI	10.1101/2024.03.01.583015
Database	MEDical Literature Analysis and Retrieval System OnLINE

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Just When We Thought We Knew Everything We Needed To Know about Zn Acquisition and Bacterial Pathogenesis.

Roop, R Martin

Journal of bacteriology

2018 Volume 200, Issue 4

Abstract: It is well established that high-affinity zinc importers play essential roles in bacterial virulence, but the studies described by Moreau et al. in this issue (G. B. Moreau, A. Qin, and B. J. Mann, J Bacteriol 200:e00587-17, 2018, https://doi.org/10.1128/ ...

Abstract	It is well established that high-affinity zinc importers play essential roles in bacterial virulence, but the studies described by Moreau et al. in this issue (G. B. Moreau, A. Qin, and B. J. Mann, J Bacteriol 200:e00587-17, 2018, https://doi.org/10.1128/JB.00587-17) demonstrate that we probably still have much to learn about how these transporters function and how the genes that encode them are regulated in different bacterial pathogens.
MeSH term(s)	Francisella ; Membrane Transport Proteins ; Zinc
Chemical Substances	Membrane Transport Proteins ; Zinc (J41CSQ7QDS)
Language	English
Publishing date	2018-01-24
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Comment
ZDB-ID	2968-3
ISSN	1098-5530 ; 0021-9193
ISSN (online)	1098-5530
ISSN	0021-9193
DOI	10.1128/JB.00694-17
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ud II Zs.50: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Editorial: Pathogenomics of the genus

Cloeckaert, Axel / Roop, R Martin / Scholz, Holger C / Whatmore, Adrian M / Zygmunt, Michel S

Frontiers in microbiology

2024 Volume 15, Page(s) 1370330

Language	English
Publishing date	2024-01-25
Publishing country	Switzerland
Document type	Editorial
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2024.1370330
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Uncovering the Hidden Credentials of

Roop, R Martin / Barton, Ian S / Hopersberger, Dariel / Martin, Daniel W

Microbiology and molecular biology reviews : MMBR

2021 Volume 85, Issue 1

Abstract: Bacteria in the ... ...

Abstract	Bacteria in the genus
MeSH term(s)	Adaptation, Physiological ; Animals ; Bacterial Outer Membrane Proteins/genetics ; Bacterial Outer Membrane Proteins/metabolism ; Brucella/genetics ; Brucella/immunology ; Brucella/pathogenicity ; Brucellosis/pathology ; Female ; Host Specificity/genetics ; Humans ; Lipopolysaccharides/immunology ; Macrophages/microbiology ; Pregnancy ; Pregnancy Complications, Infectious/microbiology ; Pregnancy Complications, Infectious/pathology ; Trophoblasts/microbiology ; Type IV Secretion Systems/genetics ; Type IV Secretion Systems/metabolism ; Virulence ; Virulence Factors
Chemical Substances	Bacterial Outer Membrane Proteins ; Lipopolysaccharides ; Type IV Secretion Systems ; Virulence Factors
Language	English
Publishing date	2021-02-10
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Review
ZDB-ID	1376131-6
ISSN	1098-5557 ; 1070-6275 ; 1092-2172
ISSN (online)	1098-5557 ; 1070-6275
ISSN	1092-2172
DOI	10.1128/MMBR.00021-19
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Ud II Zs.96: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Brucella

Barton, Ian S / Ren, Zhongqing / Cribb, Connor B / Pitzer, Joshua E / Baglivo, Ilaria / Martin, Daniel W / Wang, Xindan / Roop, R Martin

mBio

2023 , Page(s) e0220123

Abstract: Histone-like nucleoid structuring (H-NS) and H-NS-like proteins serve as global gene silencers and work with antagonistic transcriptional activators (counter-silencers) to properly coordinate the expression of virulence genes in pathogenic bacteria. ... ...

Abstract	Histone-like nucleoid structuring (H-NS) and H-NS-like proteins serve as global gene silencers and work with antagonistic transcriptional activators (counter-silencers) to properly coordinate the expression of virulence genes in pathogenic bacteria. In
Language	English
Publishing date	2023-10-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	2557172-2
ISSN	2150-7511 ; 2161-2129
ISSN (online)	2150-7511
ISSN	2161-2129
DOI	10.1128/mbio.02201-23
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Metal acquisition and virulence in Brucella.

Roop, R Martin

Animal health research reviews

2012 Volume 13, Issue 1, Page(s) 10–20

Abstract: Similar to other bacteria, Brucella strains require several biologically essential metals for their survival in vitro and in vivo. Acquiring sufficient levels of some of these metals, particularly iron, manganese and zinc, is especially challenging in ... ...

Abstract	Similar to other bacteria, Brucella strains require several biologically essential metals for their survival in vitro and in vivo. Acquiring sufficient levels of some of these metals, particularly iron, manganese and zinc, is especially challenging in the mammalian host, where sequestration of these micronutrients is a well-documented component of both the innate and acquired immune responses. This review describes the Brucella metal transporters that have been shown to play critical roles in the virulence of these bacteria in experimental and natural hosts.
MeSH term(s)	Animals ; Brucella/immunology ; Brucella/metabolism ; Brucella/pathogenicity ; Brucellosis/microbiology ; Brucellosis/veterinary ; Humans ; Iron/metabolism ; Magnesium/metabolism ; Manganese/metabolism ; Metals/metabolism ; Nickel/metabolism ; Virulence ; Zinc/metabolism
Chemical Substances	Metals ; Manganese (42Z2K6ZL8P) ; Nickel (7OV03QG267) ; Iron (E1UOL152H7) ; Magnesium (I38ZP9992A) ; Zinc (J41CSQ7QDS)
Language	English
Publishing date	2012-05-25
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S. ; Review
ZDB-ID	2072117-1
ISSN	1475-2654 ; 1466-2523
ISSN (online)	1475-2654
ISSN	1466-2523
DOI	10.1017/S1466252312000047
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 7597: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: A novel formamidase is required for riboflavin biosynthesis in invasive bacteria.

Yurgel, Svetlana N / Johnson, Skylar A / Rice, Jennifer / Sa, Na / Bailes, Clayton / Baumgartner, John / Pitzer, Josh E / Roop, R Martin / Roje, Sanja

The Journal of biological chemistry

2022 Volume 298, Issue 9, Page(s) 102377

Abstract: Biosynthesis of riboflavin (RF), the precursor of the redox cofactors FMN and FAD, was thought to be well understood in bacteria, with all the pathway enzymes presumed to be known and essential. Our previous research has challenged this view by showing ... ...

Abstract	Biosynthesis of riboflavin (RF), the precursor of the redox cofactors FMN and FAD, was thought to be well understood in bacteria, with all the pathway enzymes presumed to be known and essential. Our previous research has challenged this view by showing that, in the bacterium Sinorhizobium meliloti, deletion of the ribBA gene encoding the enzyme that catalyzes the initial steps on the RF biosynthesis pathway only causes a reduction in flavin secretion rather than RF auxotrophy. This finding led us to hypothesize that RibBA participates in the biosynthesis of flavins destined for secretion, whereas S. meliloti has another enzyme that performs this function for internal cellular metabolism. Here, we identify and biochemically characterize a novel formamidase (SMc02977) involved in the production of RF for intracellular functions in S. meliloti. This catalyst, which we named Sm-BrbF, releases formate from the early RF precursor 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate to yield 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate. We show that homologs of this enzyme are present in many bacteria, are highly abundant in the Rhizobiales order, and that sequence homologs from Brucella abortus and Liberobacter solanacearum complement the RF auxotrophy of the Sm1021ΔSMc02977 mutant. Furthermore, we show that the B. abortus enzyme (Bab2_0247, Ba-BrbF) is also an 2-amino-5-formylamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate formamidase, and that the bab2_0247 mutant is a RF auxotroph exhibiting a lower level of intracellular infection than the wildtype strain. Finally, we show that Sm-BrbF and Ba-BrbF directly interact with other RF biosynthesis pathway enzymes. Together, our results provide novel insight into the intricacies of RF biosynthesis in bacteria.
MeSH term(s)	Amidohydrolases/metabolism ; Flavin Mononucleotide ; Flavin-Adenine Dinucleotide ; Formates ; Phosphates ; Riboflavin/biosynthesis ; Sinorhizobium meliloti/enzymology
Chemical Substances	Formates ; Phosphates ; Flavin-Adenine Dinucleotide (146-14-5) ; Flavin Mononucleotide (7N464URE7E) ; Amidohydrolases (EC 3.5.-) ; formamidase (EC 3.5.1.49) ; Riboflavin (TLM2976OFR)
Language	English
Publishing date	2022-08-13
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2997-x
ISSN	1083-351X ; 0021-9258
ISSN (online)	1083-351X
ISSN	0021-9258
DOI	10.1016/j.jbc.2022.102377
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uc I Zs.108: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: The Cation Diffusion Facilitator Family Protein EmfA Confers Resistance to Manganese Toxicity in Brucella abortus 2308 and Is an Essential Virulence Determinant in Mice.

Johnsrude, Matthew J / Pitzer, Joshua E / Martin, Daniel W / Roop, R Martin

Journal of bacteriology

2019 Volume 202, Issue 1

Abstract: ... The gene ... ...

Abstract	The gene designated
MeSH term(s)	Animals ; Bacterial Proteins/physiology ; Brucella abortus/drug effects ; Brucella abortus/pathogenicity ; Cation Transport Proteins/physiology ; Female ; Manganese/toxicity ; Mice ; Mice, Inbred C57BL ; Virulence
Chemical Substances	Bacterial Proteins ; Cation Transport Proteins ; natural resistance-associated macrophage protein 1 ; Manganese (42Z2K6ZL8P)
Language	English
Publishing date	2019-12-06
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2968-3
ISSN	1098-5530 ; 0021-9193
ISSN (online)	1098-5530
ISSN	0021-9193
DOI	10.1128/JB.00357-19
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ud II Zs.50: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Metal acquisition and virulence in Brucella

Roop, R. Martin

Animal health research reviews. 2012 June, v. 13, no. 1

2012

Abstract	Similar to other bacteria, Brucella strains require several biologically essential metals for their survival in vitro and in vivo. Acquiring sufficient levels of some of these metals, particularly iron, manganese and zinc, is especially challenging in the mammalian host, where sequestration of these micronutrients is a well-documented component of both the innate and acquired immune responses. This review describes the Brucella metal transporters that have been shown to play critical roles in the virulence of these bacteria in experimental and natural hosts.
Keywords	Brucella ; bacteria ; hosts ; immune response ; iron ; mammals ; manganese ; transporters ; virulence ; zinc
Language	English
Dates of publication	2012-06
Size	p. 10-20.
Publishing place	Cambridge University Press
Document type	Article
ZDB-ID	2072117-1
ISSN	1475-2654 ; 1466-2523
ISSN (online)	1475-2654
ISSN	1466-2523
DOI	10.1017/S1466252312000047
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 7597: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED