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  1. Book ; Online: Serafino Zappacosta and the Ceppellini School: A Pioneer Model For Nurturing Education in Immunology

    Di Rosa, Francesca / Carbone, Ennio

    2020  

    Keywords Medicine ; Immunology ; Serafino Zappacosta ; Ceppellini School ; Anti-tumor immunity ; Immunological memory and vaccines ; Immunity to intracellular bacteria ; Transplant immunology ; Adaptive Immunity ; Innate Immunity
    Size 1 electronic resource (108 pages)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021231343
    ISBN 9782889660506 ; 2889660508
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: ASO Author Reflections: Preoperative Assessment of Nodal Burden in Breast Cancer.

    Farley, Clara / Hwang, Rosa F

    Annals of surgical oncology

    2023  Volume 31, Issue 1, Page(s) 382–383

    MeSH term(s) Humans ; Female ; Breast Neoplasms/surgery ; Breast
    Language English
    Publishing date 2023-10-20
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-023-14326-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: L'âge d'or du totémisme

    Rosa, Frederico

    2003  

    Abstract: Le totémisme fut l'objet, il y a cent ans, du plus grand débat anthropologique de tous les temps. Cette notion clé de la théorie évolutionniste tomba par la suite en désuétude, en attendant le coup de grâce que lui donna Lévi-Strauss dans Le Totémisme ... ...

    Abstract Le totémisme fut l'objet, il y a cent ans, du plus grand débat anthropologique de tous les temps. Cette notion clé de la théorie évolutionniste tomba par la suite en désuétude, en attendant le coup de grâce que lui donna Lévi-Strauss dans Le Totémisme aujourd'hui. Or, elle fut essentielle à l'avènement de l'ethnologie moderne. Des figures comme Franz Boas, Émile Durkheim, Malinowski ou Radcliffe Brown entrèrent en dialogue avec les auteurs évolutionnistes qui avaient lancé la discussion, en p..
    Size 1 electronic resource ( p.)
    Publisher CNRS Éditions
    Document type Book ; Online
    Note French ; Open Access
    HBZ-ID HT020089414
    ISBN 9782271061164 ; 9782271078100 ; 2271061164 ; 2271078105
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Book ; Online: Lâge dor du totémisme : Histoire dun débat anthropologique (1887-1929)

    Rosa, Frederico

    2003  

    Abstract: Le totémisme fut lobjet, il y a cent ans, du plus grand débat anthropologique de tous les temps. Cette notion clé de la théorie évolutionniste tomba par la suite en désuétude, en attendant le coup de grâce que lui donna Lévi-Strauss dans Le Totémisme ... ...

    Abstract Le totémisme fut lobjet, il y a cent ans, du plus grand débat anthropologique de tous les temps. Cette notion clé de la théorie évolutionniste tomba par la suite en désuétude, en attendant le coup de grâce que lui donna Lévi-Strauss dans Le Totémisme aujourdhui. Or, elle fut essentielle à lavènement de lethnologie moderne. Des figures comme Franz Boas, Émile Durkheim, Malinowski ou Radcliffe Brown entrèrent en dialogue avec les auteurs évolutionnistes qui avaient lancé la discussion, en particulier lÉcossais James Frazer, auteur du célèbre Rameau dor. Louvrage de Frederico Rosa fait, pour la première fois, lhistoire de ce débat devenu mythique. Son approche, qui contraste avec les tendances postmodernes, prend très au sérieux la vaste bibliographie de la Belle Époque anglaise, française, américaine et germanique traitant du totémisme. Dun nom à lautre ou au fil des publications dun même auteur, il dégage les continuités, les ruptures et les interprétations nouvelles. Cest la dramaturgie des idées qui prend ainsi forme, comme dit Patrick Menget dans la préface. Le totémisme, entendu dabord comme religion du sang que partageaient hommes et animaux, devint aussitôt le prétexte des polémiques les plus acharnées, que lauteur exhume et éclaire avec le sens du suspense. Le lecteur se prend au jeu, curieux de découvrir comment la parenté et lanthropologie religieuse se combinent dans le concept stratégique de totémisme, puis se séparent et se transforment. Quant aux autres sciences humaines, elles y trouveront une part de leur histoire, elles aussi, dans la mesure où le débat proprement anthropologique eut dimportantes répercussions sur tous les domaines voisins, de la sociologie et lhistoire des religions à larchéologie, la philosophie et la psychanalyse
    Keywords Social sciences (General)
    Size 1 electronic resource ( pages)
    Publisher Éditions de la Maison des sciences de l'homme
    Document type Book ; Online
    Note French ; Open Access
    HBZ-ID HT020321232
    ISBN 9782735119004 ; 2735119009
    DOI 10.4000/books.editionsmsh.6835
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article ; Online: Laparoscopic Gastrectomy for Locally Advanced Gastric Cancer.

    Rosa, Fausto / Alfieri, Sergio

    JAMA surgery

    2022  Volume 157, Issue 6, Page(s) 545–546

    MeSH term(s) Gastrectomy ; Humans ; Laparoscopy ; Lymph Node Excision ; Stomach Neoplasms/surgery ; Treatment Outcome
    Language English
    Publishing date 2022-02-16
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2701841-6
    ISSN 2168-6262 ; 2168-6254
    ISSN (online) 2168-6262
    ISSN 2168-6254
    DOI 10.1001/jamasurg.2021.7582
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Impact of muscle mass loss on outcomes in advanced or metastatic gastric cancer patients receiving a second-line treatment.

    Zurlo, V / Rosa, F / Rinninella, E / Pontolillo, L / Beccia, V / Maratta, M / Tortora, G / Alfieri, S / Pozzo, C / Strippoli, A

    European review for medical and pharmacological sciences

    2024  Volume 28, Issue 4, Page(s) 1575–1584

    Abstract: Objective: Sarcopenia is a frequent disorder among cancer patients. It commonly leads to muscle mass wasting and poor clinical outcomes, even though it is rarely recognized and often undertreated. The relationship between skeletal muscle depletion and ... ...

    Abstract Objective: Sarcopenia is a frequent disorder among cancer patients. It commonly leads to muscle mass wasting and poor clinical outcomes, even though it is rarely recognized and often undertreated. The relationship between skeletal muscle depletion and chemotherapy toxicity or postoperative complications is well known. The aim of the present study was to analyze the impact of sarcopenia on clinical outcomes of pretreated metastatic gastric cancer (GC) patients.
    Patients and methods: 88 pretreated GC patients were retrospectively analyzed. Patients were divided into two groups according to their skeletal mass index (SMI): sarcopenic patients with low SMI (≤39 cm2/m2 for women and ≤55 cm2/m2 for men) and non-sarcopenic patients with normal/high SMI value. The two groups were compared according to outcomes and adverse events.
    Results: Progression-free survival (PFS) was significantly higher in patients with normal/high SMI than in those with low SMI (6 vs. 3.5 months, respectively; HR 0.52). Similarly, the overall response rate (ORR) was higher in the subgroup with normal/high SMI (41% vs. 20%; p=0.02). Overall survival (OS) was not significantly different, but multivariate analysis demonstrated that both SMI and performance status were associated with OS. In the sarcopenic group, the patients treated in the second line with paclitaxel and ramucirumab regimen showed a better outcome profile. Overall, adverse events (AEs) were more frequent in the group of patients with low SMI (p<0.0001).
    Conclusions: Early recognition of sarcopenia may contribute to personalizing second or further lines of treatment in advanced GC and to weigh up the potential risk of serious toxicities.
    MeSH term(s) Male ; Humans ; Female ; Sarcopenia ; Stomach Neoplasms/drug therapy ; Retrospective Studies ; Muscular Atrophy ; Muscle, Skeletal
    Language English
    Publishing date 2024-03-04
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605550-3
    ISSN 2284-0729 ; 1128-3602 ; 0392-291X
    ISSN (online) 2284-0729
    ISSN 1128-3602 ; 0392-291X
    DOI 10.26355/eurrev_202402_35486
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Short communication: Comparative gene expression analysis on the enrichment of polymorphonuclear leukocytes and gastrointestinal epithelial cells in fecal RNA from nondiarrheic neonatal dairy calves.

    Rosa, F / Osorio, J S

    Journal of dairy science

    2019  Volume 102, Issue 8, Page(s) 7464–7468

    Abstract: Increased understanding of the biology of the gastrointestinal tract (GIT) in neonatal dairy calves during their adaptation to an extrauterine environment will decrease health problems such as diarrhea while increasing feed efficiency and average daily ... ...

    Abstract Increased understanding of the biology of the gastrointestinal tract (GIT) in neonatal dairy calves during their adaptation to an extrauterine environment will decrease health problems such as diarrhea while increasing feed efficiency and average daily gain in preweaned dairy calves. Within this context, a noninvasive method, based on fecal RNA, to study the GIT in neonatal dairy calves through the isolation of RNA from fecal samples for quantitative reverse-transcription PCR analysis can provide valuable information on GIT biological adaptations during the preweaning period. We aimed to evaluate the potential enrichment of RNA from immune cells or GIT epithelial cells during fecal RNA isolation. Eight neonatal Holstein calves less than 3 wk old (14.9 ± 5.5 d of age at sampling ± standard deviation) and a fecal score of 2.0 ± 0.7 (mean ± standard deviation) were used. During a single sampling, fecal and blood samples were taken simultaneously from each calf before the morning feeding. Fecal samples were immediately frozen in liquid nitrogen until RNA isolation, whereas polymorphonuclear leukocytes (PMN) were isolated from blood samples before RNA isolation. An quantitative reverse-transcription PCR analysis was performed using a single standard curve composited of equal amounts of all samples including cDNA from fecal and PMN. The genes myeloperoxidase (MPO) and L-selectin (SELL) were selected for their specific known function in PMN, whereas keratin 8 (KRT8) and aquaporin 3 (AQP3) have been associated with epithelial enterocytes. Our results showed a contrasting gene expression profile between PMN and fecal RNA; whereas greater mRNA expression of SELL was observed in PMN, a greater KRT8 expression was observed in fecal RNA. The mRNA expression of AQP3 tended to be greater in PMN than fecal RNA. Additionally, MPO was not amplified in fecal RNA. Our findings suggest that under nondiarrheic conditions RNA isolated from stool samples of neonatal dairy calves will have a considerable number of GIT epithelial cells, which confirms the reliability of this method under these conditions. However, further research needs to be done to determine if the same effects are observed during diarrhea or throughout the preweaning period of dairy calves.
    MeSH term(s) Animal Feed ; Animals ; Cattle/genetics ; Cattle/immunology ; Diarrhea/veterinary ; Feces/chemistry ; Gastrointestinal Tract/cytology ; Gastrointestinal Tract/immunology ; Gene Expression Profiling/veterinary ; Intestinal Mucosa/cytology ; Leukocyte Count/veterinary ; Neutrophils ; RNA/metabolism ; Reproducibility of Results
    Chemical Substances RNA (63231-63-0)
    Language English
    Publishing date 2019-06-06
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 242499-x
    ISSN 1525-3198 ; 0022-0302
    ISSN (online) 1525-3198
    ISSN 0022-0302
    DOI 10.3168/jds.2018-16074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Cavernous sinus thrombosis associated with intraparenchymal hemorrhage and brainstem venous infarction as a rare complication of fronto-orbital infection.

    Rosa, F / Renzetti, P / Castellan, L / Roccatagliata, L

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2021  Volume 43, Issue 1, Page(s) 731–734

    MeSH term(s) Brain Stem/diagnostic imaging ; Brain Stem Infarctions ; Cavernous Sinus ; Cavernous Sinus Thrombosis/diagnostic imaging ; Cavernous Sinus Thrombosis/etiology ; Hemorrhage ; Humans
    Language English
    Publishing date 2021-10-18
    Publishing country Italy
    Document type Letter
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-021-05658-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Dataset and measurements from a current density sensor during experimental testing of dynamic load cycling for a parallel-serpentine design of a proton exchange membrane fuel cell.

    Toharias, Baltasar / Suárez, Christian / Iranzo, Alfredo / Salva, María / Rosa, Felipe

    Data in brief

    2024  Volume 54, Page(s) 110392

    Abstract: A dataset from experimental tests of a proton exchange membrane fuel cell (PEMFC) with an active area of approximately 50 ... ...

    Abstract A dataset from experimental tests of a proton exchange membrane fuel cell (PEMFC) with an active area of approximately 50 cm
    Language English
    Publishing date 2024-04-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2786545-9
    ISSN 2352-3409 ; 2352-3409
    ISSN (online) 2352-3409
    ISSN 2352-3409
    DOI 10.1016/j.dib.2024.110392
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Short communication: Comparative gene expression analysis on the enrichment of polymorphonuclear leukocytes and gastrointestinal epithelial cells in fecal RNA from nondiarrheic neonatal dairy calves

    Rosa, F / Osorio, J.S

    American Dairy Science Association Journal of dairy science. 2019 Aug., v. 102, no. 8

    2019  

    Abstract: Increased understanding of the biology of the gastrointestinal tract (GIT) in neonatal dairy calves during their adaptation to an extrauterine environment will decrease health problems such as diarrhea while increasing feed efficiency and average daily ... ...

    Abstract Increased understanding of the biology of the gastrointestinal tract (GIT) in neonatal dairy calves during their adaptation to an extrauterine environment will decrease health problems such as diarrhea while increasing feed efficiency and average daily gain in preweaned dairy calves. Within this context, a noninvasive method, based on fecal RNA, to study the GIT in neonatal dairy calves through the isolation of RNA from fecal samples for quantitative reverse-transcription PCR analysis can provide valuable information on GIT biological adaptations during the preweaning period. We aimed to evaluate the potential enrichment of RNA from immune cells or GIT epithelial cells during fecal RNA isolation. Eight neonatal Holstein calves less than 3 wk old (14.9 ± 5.5 d of age at sampling ± standard deviation) and a fecal score of 2.0 ± 0.7 (mean ± standard deviation) were used. During a single sampling, fecal and blood samples were taken simultaneously from each calf before the morning feeding. Fecal samples were immediately frozen in liquid nitrogen until RNA isolation, whereas polymorphonuclear leukocytes (PMN) were isolated from blood samples before RNA isolation. An quantitative reverse-transcription PCR analysis was performed using a single standard curve composited of equal amounts of all samples including cDNA from fecal and PMN. The genes myeloperoxidase (MPO) and L-selectin (SELL) were selected for their specific known function in PMN, whereas keratin 8 (KRT8) and aquaporin 3 (AQP3) have been associated with epithelial enterocytes. Our results showed a contrasting gene expression profile between PMN and fecal RNA; whereas greater mRNA expression of SELL was observed in PMN, a greater KRT8 expression was observed in fecal RNA. The mRNA expression of AQP3 tended to be greater in PMN than fecal RNA. Additionally, MPO was not amplified in fecal RNA. Our findings suggest that under nondiarrheic conditions RNA isolated from stool samples of neonatal dairy calves will have a considerable number of GIT epithelial cells, which confirms the reliability of this method under these conditions. However, further research needs to be done to determine if the same effects are observed during diarrhea or throughout the preweaning period of dairy calves.
    Keywords Holstein ; RNA ; aquaporins ; average daily gain ; blood sampling ; complementary DNA ; dairy calves ; diarrhea ; enterocytes ; feces ; feed conversion ; gene expression ; genes ; keratin ; liquids ; myeloperoxidase ; neutrophils ; nitrogen ; reverse transcriptase polymerase chain reaction ; standard deviation
    Language English
    Dates of publication 2019-08
    Size p. 7464-7468.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 242499-x
    ISSN 1525-3198 ; 0022-0302
    ISSN (online) 1525-3198
    ISSN 0022-0302
    DOI 10.3168/jds.2018-16074
    Database NAL-Catalogue (AGRICOLA)

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