LIVIVO - Search results -

Search results

Result 1 - 10 of total 49

Search options

Article ; Online: Fentanyl-Induced Thrombocytopenia.

Rosas, Daniel

2020 Volume 27, Issue 5, Page(s) e509–e511

MeSH term(s)	Anesthetics, Intravenous/administration & dosage ; Anesthetics, Intravenous/adverse effects ; Bronchiolitis Obliterans/surgery ; Female ; Fentanyl/administration & dosage ; Fentanyl/adverse effects ; Humans ; Lung Transplantation/adverse effects ; Middle Aged ; Pain, Postoperative/etiology ; Pain, Postoperative/prevention & control ; Platelet Count ; Thrombocytopenia/blood ; Thrombocytopenia/chemically induced ; Thrombocytopenia/diagnosis
Chemical Substances	Anesthetics, Intravenous ; Fentanyl (UF599785JZ)
Language	English
Publishing date	2020-11-04
Publishing country	United States
Document type	Case Reports ; Letter
ZDB-ID	1280786-2
ISSN	1536-3686 ; 1075-2765
ISSN (online)	1536-3686
ISSN	1075-2765
DOI	10.1097/MJT.0000000000001167
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4351: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Signal processing and machine learning algorithm to classify anaesthesia depth.

Mosquera Dussan, Oscar / Tuta-Quintero, Eduardo / Botero-Rosas, Daniel A

BMJ health & care informatics

2023 Volume 30, Issue 1

Abstract: Background: Poor assessment of anaesthetic depth (AD) has led to overdosing or underdosing of the anaesthetic agent, which requires continuous monitoring to avoid complications. The evaluation of the central nervous system activity and autonomic nervous ...

Abstract	Background: Poor assessment of anaesthetic depth (AD) has led to overdosing or underdosing of the anaesthetic agent, which requires continuous monitoring to avoid complications. The evaluation of the central nervous system activity and autonomic nervous system could provide additional information on the monitoring of AD during surgical procedures. Methods: Observational analytical single-centre study, information on biological signals was collected during a surgical procedure under general anaesthesia for signal preprocessing, processing and postprocessing to feed a pattern classifier and determine AD status of patients. The development of the electroencephalography index was carried out through data processing and algorithm development using MATLAB V.8.1. Results: A total of 25 men and 35 women were included, with a total time of procedure average of 109.62 min. The results show a high Pearson correlation between the Complexity Brainwave Index and the indices of the entropy module. A greater dispersion is observed in the state entropy and response entropy indices, a partial overlap can also be seen in the boxes associated with deep anaesthesia and general anaesthesia in these indices. A high Pearson correlation might be explained by the coinciding values corresponding to the awake and general anaesthesia states. A high Pearson correlation might be explained by the coinciding values corresponding to the awake and general anaesthesia states. Conclusion: Biological signal filtering and a machine learning algorithm may be used to classify AD during a surgical procedure. Further studies will be needed to confirm these results and improve the decision-making of anaesthesiologists in general anaesthesia.
MeSH term(s)	Male ; Humans ; Female ; Anesthetics ; Anesthesia, General/methods ; Electroencephalography/methods ; Algorithms
Chemical Substances	Anesthetics
Language	English
Publishing date	2023-10-02
Publishing country	England
Document type	Observational Study ; Journal Article
ISSN	2632-1009
ISSN (online)	2632-1009
DOI	10.1136/bmjhci-2023-100823
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Review of the Agnostic-Type Treatment Approach: Treating Cancer by Mutations, Not by Location.

Rosas, Daniel / Raez, Luis E

Oncology and therapy

2020 Volume 8, Issue 1, Page(s) 59–66

Abstract: Recent years has seen the discovery and description of genetic alterations responsible for oncogenesis in a wide variety of cancers, together with the finding that some markers are actionable and can be targeted by medications. Such developments have ... ...

Abstract	Recent years has seen the discovery and description of genetic alterations responsible for oncogenesis in a wide variety of cancers, together with the finding that some markers are actionable and can be targeted by medications. Such developments have enabled cancer treatments to evolve from empirical palliative chemotherapy, with low chances of response or curative intent in most types of cancers, to targeted therapy, with some studies showing promising results in terms of improved overall response rates, overall survival and quality of life, although, like all new groups of medications, with specific adverse effect profiles. This treatment evolution is a major development in cancer therapy. Tumors were originally classified as solid or liquid tumors based on their location in the human body (solid organs or blood), which evolved into the medical specialties of medical oncology and clinical hematology, respectively. Subsequently, tumors were classified by the organ they originate from, in the belief that the origin of the tumor would guide its biological behavior and would faciliate understanding of their mechanism of spread and, potentially, of the best treatment approach. Although this latter approach has achieved some success over the many years it has been applied, there have been major disappointments, particularly in lung cancers for which palliative chemotherapy has only been able to provide a median survival of around 1 year and a complete remission rate of < 5%. We are now understanding that this concept of cancer pathophysiology is more complex, but also potentially simple, and that one or several molecular aberrations are probably responsible for the origin of each cancer. Various molecular alterations have been described, although the relevance of each alteration is not yet fully understood. In this article, we highlight clinical trial designs, biologic issues, and regulatory issues leading to the development of medications for tissue-agnostic treatment.
Language	English
Publishing date	2020-05-02
Publishing country	New Zealand
Document type	Journal Article ; Review
ZDB-ID	2848647-X
ISSN	2366-1089 ; 2366-1070
ISSN (online)	2366-1089
ISSN	2366-1070
DOI	10.1007/s40487-020-00114-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Anaphylactic Shock and Cardiac Arrest Secondary to Aprepitant.

Rosas, Daniel / Raez, Luis E

American journal of therapeutics

2020 Volume 27, Issue 6, Page(s) e640–e642

MeSH term(s)	Anaphylaxis/chemically induced ; Aprepitant ; Heart Arrest/chemically induced ; Humans
Chemical Substances	Aprepitant (1NF15YR6UY)
Language	English
Publishing date	2020-08-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	1280786-2
ISSN	1536-3686 ; 1075-2765
ISSN (online)	1536-3686
ISSN	1075-2765
DOI	10.1097/MJT.0000000000001133
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4351: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Harnessing the omics revolution to address the global biodiversity crisis

De León, Luis F / Silva, Bruna / Avilés-Rodríguez, Kevin J / Buitrago-Rosas, Daniel

Current Opinion in Biotechnology. 2023 Apr., v. 80 p.102901-

2023

Abstract: Human disturbances are altering global biodiversity in unprecedented ways. We identify three fundamental challenges underpinning our understanding of global biodiversity (namely discovery, loss, and preservation), and discuss how the omics revolution (e ... ...

Abstract	Human disturbances are altering global biodiversity in unprecedented ways. We identify three fundamental challenges underpinning our understanding of global biodiversity (namely discovery, loss, and preservation), and discuss how the omics revolution (e.g. genomics, transcriptomics, proteomics, metabolomics, and meta-omics) can help address these challenges. We also discuss how omics tools can illuminate the major drivers of biodiversity loss, including invasive species, pollution, urbanization, overexploitation, and climate change, with a special focus on highly diverse tropical environments. Although omics tools are transforming the traditional toolkit of biodiversity research, their application to addressing the current biodiversity crisis remains limited and may not suffice to offset current rates of biodiversity loss. Despite technical and logistical challenges, omics tools need to be fully integrated into global biodiversity research, and better strategies are needed to improve their translation into biodiversity policy and practice. It is also important to recognize that although the omics revolution can be considered the biologist’s dream, socioeconomic disparity limits their application in biodiversity research.
Keywords	biodiversity ; biotechnology ; climate change ; genomics ; humans ; invasive species ; issues and policy ; metabolomics ; pollution ; proteomics ; transcriptomics ; urbanization
Language	English
Dates of publication	2023-04
Publishing place	Elsevier Ltd
Document type	Article ; Online
ZDB-ID	1052045-4
ISSN	1879-0429 ; 0958-1669
ISSN (online)	1879-0429
ISSN	0958-1669
DOI	10.1016/j.copbio.2023.102901
Database	NAL-Catalogue (AGRICOLA)

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 3071: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Cerebral rScO2 Measured by Near-Infrared Spectroscopy (NIRS) During Therapeutic Hypothermia in Neonates with Hypoxic-Ischemic Encephalopathy: A Systematic Review.

Agudelo-Pérez, Sergio / Troncoso, Gloria / Roa, Alejandra / Ariza, Ana Gabriela / Doumat, Georgina / Reinoso, Natalia M / Botero-Rosas, Daniel

Journal of mother and child

2024 Volume 28, Issue 1, Page(s) 33–44

Abstract: Introduction: Perinatal asphyxia, a leading cause of neonatal mortality and neurological sequelae, necessitates early detection of pathophysiological neurologic changes during hypoxic-ischaemic encephalopathy (HIE). This study aimed to review published ... ...

Abstract	Introduction: Perinatal asphyxia, a leading cause of neonatal mortality and neurological sequelae, necessitates early detection of pathophysiological neurologic changes during hypoxic-ischaemic encephalopathy (HIE). This study aimed to review published data on rScO2 monitoring during hypothermia treatment in neonates with perinatal asphyxia to predict short- and long-term neurological injury. Methods: A systematic review was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Study identification was performed through a search between November and December 2021 in the electronic databases PubMed, Embase, Lilacs, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials (CENTRAL). The main outcome was short-term (Changes in brain magnetic resonating imaging) and long-term (In neurodevelopment) neurological injury. The study protocol was registered in PROSPERO (International Prospective Register of Systematic Reviews) with CRD42023395438. Results: 380 articles were collected from databases in the initial search. Finally, 15 articles were selected for extraction and analysis of the information. An increase in rScO2 measured by NIRS (Near-infrared spectroscopy) at different moments of treatment predicts neurological injury. However, there exists a wide variability in the methods and outcomes of the studies. Conclusion: High rScO2 values were found to predict negative outcomes, with substantial discord among studies. NIRS is proposed as a real-time bedside tool for predicting brain injury in neonates with moderate to severe HIE.
MeSH term(s)	Infant, Newborn ; Humans ; Hypoxia-Ischemia, Brain/diagnostic imaging ; Hypoxia-Ischemia, Brain/therapy ; Spectroscopy, Near-Infrared ; Asphyxia/complications ; Asphyxia/therapy ; Brain/diagnostic imaging ; Hypothermia, Induced/adverse effects ; Hypothermia, Induced/methods ; Asphyxia Neonatorum/complications ; Asphyxia Neonatorum/therapy ; Asphyxia Neonatorum/diagnosis
Language	English
Publishing date	2024-04-19
Publishing country	Poland
Document type	Systematic Review ; Journal Article ; Review
ISSN	2719-535X
ISSN (online)	2719-535X
DOI	10.34763/jmotherandchild.20242801.d-24-00010
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Harnessing the omics revolution to address the global biodiversity crisis.

De León, Luis F / Silva, Bruna / Avilés-Rodríguez, Kevin J / Buitrago-Rosas, Daniel

Current opinion in biotechnology

2023 Volume 80, Page(s) 102901

Abstract	Human disturbances are altering global biodiversity in unprecedented ways. We identify three fundamental challenges underpinning our understanding of global biodiversity (namely discovery, loss, and preservation), and discuss how the omics revolution (e.g. genomics, transcriptomics, proteomics, metabolomics, and meta-omics) can help address these challenges. We also discuss how omics tools can illuminate the major drivers of biodiversity loss, including invasive species, pollution, urbanization, overexploitation, and climate change, with a special focus on highly diverse tropical environments. Although omics tools are transforming the traditional toolkit of biodiversity research, their application to addressing the current biodiversity crisis remains limited and may not suffice to offset current rates of biodiversity loss. Despite technical and logistical challenges, omics tools need to be fully integrated into global biodiversity research, and better strategies are needed to improve their translation into biodiversity policy and practice. It is also important to recognize that although the omics revolution can be considered the biologist's dream, socioeconomic disparity limits their application in biodiversity research.
MeSH term(s)	Humans ; Genomics ; Proteomics ; Biodiversity ; Metabolomics
Language	English
Publishing date	2023-02-10
Publishing country	England
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	1052045-4
ISSN	1879-0429 ; 0958-1669
ISSN (online)	1879-0429
ISSN	0958-1669
DOI	10.1016/j.copbio.2023.102901
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 3071: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article: A narrative review of biosimilars: a continued journey from the scientific evidence to practice implementation.

García, Jorge J / Raez, Luis E / Rosas, Daniel

Translational lung cancer research

2020 Volume 9, Issue 5, Page(s) 2113–2119

Abstract: Biologic agents have revolutionized the management of serious health conditions in the last two decades. The use of "targeted therapy" brings not only better progression free survivals and overall survivals, but also better toxicity profiles and quality ... ...

Abstract	Biologic agents have revolutionized the management of serious health conditions in the last two decades. The use of "targeted therapy" brings not only better progression free survivals and overall survivals, but also better toxicity profiles and quality of life benefits, compared to empirical palliative chemotherapy. However, given the high cost associated with biologic drugs and the sharp increases in biologic drug utilization, this drug category has significantly raised healthcare cost over the years. A similar phenomenon was previously experienced with branded simple chemical compound drugs, including chemotherapeutic agents, which was largely mitigated by the introduction of a generic approval pathway, decreasing the costs of the drugs, making them more affordable, given to the increase in competition among the drug makers. A similar opportunity presents years later with the completion of the full patent exclusivity period of many biologics. However, the ending of patent exclusivity, although enables more market competition, does not guarantee market penetration. Stakeholders, such as patients, providers and payers, must build trust and confidence in the science of biosimilars and the product specific studies leading to FDA approval in order to incorporate these products to practice and enable the biosimilar market at large to reach the potential to significantly contribute to reductions in drug cost. Dissemination of scientific and emerging biosimilar evidence is paramount in order to support stakeholder informed decision making and enable each to benefit from expanded treatment options. This paper describes the biosimilar development, approval process, and reviews a number of challenges with the marketing implementation of biosimilars.
Language	English
Publishing date	2020-11-18
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2754335-3
ISSN	2226-4477 ; 2218-6751
ISSN (online)	2226-4477
ISSN	2218-6751
DOI	10.21037/tlcr-20-601
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Neuregulin 1 Gene (

Rosas, Daniel / Raez, Luis E / Russo, Alessandro / Rolfo, Christian

Cancers

2021 Volume 13, Issue 20

Abstract: Oncogenic gene fusions are hybrid genes that result from structural DNA rearrangements, leading to unregulated cell proliferation by different mechanisms in a wide variety of cancer. This has led to the development of directed therapies to antagonize a ... ...

Abstract	Oncogenic gene fusions are hybrid genes that result from structural DNA rearrangements, leading to unregulated cell proliferation by different mechanisms in a wide variety of cancer. This has led to the development of directed therapies to antagonize a variety of mechanisms that lead to cell growth or proliferation. Multiple oncogene fusions are currently targeted in lung cancer treatment, such as those involving
Language	English
Publishing date	2021-10-09
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers13205038
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: The Challenges of Spirometric Diagnosis of COPD.

Maldonado-Franco, Adriana / Giraldo-Cadavid, Luis F / Tuta-Quintero, Eduardo / Bastidas Goyes, Alirio R / Botero-Rosas, Daniel A

Canadian respiratory journal

2023 Volume 2023, Page(s) 6991493

Abstract: Chronic obstructive pulmonary disease (COPD) is one of the top causes of morbidity and mortality worldwide. Although for many years its accurate diagnosis has been a focus of intense research, it is still challenging. Due to its simplicity, portability, ... ...

Abstract	Chronic obstructive pulmonary disease (COPD) is one of the top causes of morbidity and mortality worldwide. Although for many years its accurate diagnosis has been a focus of intense research, it is still challenging. Due to its simplicity, portability, and low cost, spirometry has been established as the main tool to detect this condition, but its flawed performance makes it an imperfect COPD diagnosis gold standard. This review aims to provide an up-to-date literature overview of recent studies regarding COPD diagnosis; we seek to identify their limitations and establish perspectives for spirometric diagnosis of COPD in the XXI century by combining deep clinical knowledge of the disease with advanced computer analysis techniques.
MeSH term(s)	Humans ; Forced Expiratory Volume ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Severity of Illness Index ; Spirometry
Language	English
Publishing date	2023-09-29
Publishing country	Egypt
Document type	Journal Article ; Review
ZDB-ID	1213103-9
ISSN	1916-7245 ; 1198-2241
ISSN (online)	1916-7245
ISSN	1198-2241
DOI	10.1155/2023/6991493
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4140: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito