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Article ; Online: Malaysian Society of Colorectal Surgeons (MSCRS): April Camilla Roslani, President (2021-2023): April Camilla Roslani, President (2021-2023).

Roslani, April Camilla

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

2022 Volume 24, Issue 3, Page(s) 255–256

MeSH term(s)	Asians ; Colorectal Neoplasms/surgery ; History, 20th Century ; Humans ; Surgeons
Language	English
Publishing date	2022-03-20
Publishing country	England
Document type	Historical Article ; Journal Article
ZDB-ID	1440017-0
ISSN	1463-1318 ; 1462-8910
ISSN (online)	1463-1318
ISSN	1462-8910
DOI	10.1111/codi.16113
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Article ; Online: Laser ablation of anal fistulae: a 6-year experience in a tertiary teaching hospital in Malaysia.

Tang, Chu-Yik / Roslani, April Camilla

Lasers in medical science

2022 Volume 37, Issue 8, Page(s) 3291–3296

Abstract: Background: Several studies have investigated the role of laser ablation of anal fistulae in the European setting. However, long-term follow-up results following laser fistula ablations are not widely investigated and no study was performed in the Asia- ... ...

Abstract	Background: Several studies have investigated the role of laser ablation of anal fistulae in the European setting. However, long-term follow-up results following laser fistula ablations are not widely investigated and no study was performed in the Asia-Pacific, a region with a distinctive prevalence of tuberculosis. The primary objective of this study is to report a single-centre experience with laser ablation of anal fistulae in Malaysia over a period of 6 years. Method: This was a retrospective observational study assessing the outcomes following 70 laser ablations of anal fistulae from February 2014 till December 2019. All cases were assessed using endoanal ultrasound. The laser ablation procedures were performed using laser systems and fibres from Endoteq Medizinische Laser GmBH, Germany, and Biolitec AG, Jena, Germany. Laser fibres were introduced into the fistula tract and laser energy was emitted radially in continuous mode when activated during the procedure. Pre-defined post-procedural outcomes (primary healing, healing failure or recurrence) were recorded as either present or absent during subsequent follow-up appointments and the data was analysed. Results: Over a median follow-up period of 10 months, primary healing was reported following 42 procedures (60.0%). Healing failure was reported following 28 procedures (40.0%) whilst recurrence was seen after 16 procedures (22.86%). No new cases of incontinence were reported following the procedure. Conclusion: The reported primary healing rate following laser ablation of anal fistulae in this study appears consistent with existing literature published by other international centres. The most apparent clinical advantage of this procedure is sphincter-function preservation. However, the primary healing rate after isolated laser fistula ablation is still suboptimal. Judicious patient selection and application in anal fistulae with suitable characteristics could potentially improve the post-procedural outcomes.
MeSH term(s)	Anal Canal/surgery ; Hospitals, Teaching ; Humans ; Laser Therapy/methods ; Malaysia/epidemiology ; Rectal Fistula/surgery ; Recurrence ; Treatment Outcome
Language	English
Publishing date	2022-08-31
Publishing country	England
Document type	Journal Article ; Observational Study
ZDB-ID	632808-8
ISSN	1435-604X ; 0268-8921
ISSN (online)	1435-604X
ISSN	0268-8921
DOI	10.1007/s10103-022-03628-7
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Article ; Online: Comparison of post-operative bleeding incidence in laser hemorrhoidoplasty with and without hemorrhoidal artery ligation: a double-blinded randomized controlled trial.

Lim, Shu Yu / Rajandram, Retnagowri / Roslani, April Camilla

BMC surgery

2022 Volume 22, Issue 1, Page(s) 146

Abstract: Introduction: The effectiveness of hemorrhoidal artery ligation supplementation in reducing the incidence of post laser hemorrhoidoplasty bleeding has not been investigated.: Methods: This was a double-blind, randomized controlled trial comparing ... ...

Abstract	Introduction: The effectiveness of hemorrhoidal artery ligation supplementation in reducing the incidence of post laser hemorrhoidoplasty bleeding has not been investigated. Methods: This was a double-blind, randomized controlled trial comparing post-operative bleeding incidence in patients undergoing laser hemorrhoidoplasty (LHP) only versus LHP with hemorrhoidal artery ligation (HAL). Outcome measures included post-operative bleeding and its severity (i.e. verbal rating scale and Clavien-Dindo classification), presence of perianal swelling and pain score (visual analog score) at 1-day, 1-week and 6-weeks post-operatively. Statistical tests were performed and a value of P < 0.05 was considered significant. Results: Seventy-six patients were randomized. There was no difference in median operating time. The bleeding incidence was highest at 1-week post-operatively (17.1%), and decreased to 1.3% at 6-weeks. There was no significant difference in bleeding incidence between both groups at any of the measured timepoints (P > 0.05). Severity of bleeding and incidence of post-operative perianal swelling were similar in both groups (P > 0.05). There was no difference in median pain scores. Conclusion: Supplementation of HAL to LHP does not reduce the post-operative bleeding incidence. LHP is sufficient as a stand-alone procedure for treating haemorrhoids. Trial registration: National Registration Number is NMRR-15-1112-24065 (IIR). The trial start date was 1st January 2015 with the ClinicalTrials.gov identifier and registration number as NCT04667169.
MeSH term(s)	Arteries/surgery ; Hemorrhoids/surgery ; Humans ; Incidence ; Lasers ; Ligation ; Pain ; Pain, Postoperative/epidemiology ; Postoperative Hemorrhage ; Treatment Outcome
Language	English
Publishing date	2022-04-21
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	2050442-1
ISSN	1471-2482 ; 1471-2482
ISSN (online)	1471-2482
ISSN	1471-2482
DOI	10.1186/s12893-022-01594-z
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Article: Cultural Sensitivity and Ethical Considerations.

Bobel, Matthew Cronon / Al Hinai, Alreem / Roslani, April Camilla

Clinics in colon and rectal surgery

2022 Volume 35, Issue 5, Page(s) 371–375

Abstract: Global surgery is a burgeoning area of global health. Surgeons can engage in one-or many-of the facets of global healthcare delivery: clinical care, capacity building, education, research, etc. Working in an increasingly global community, surgeons must ... ...

Abstract	Global surgery is a burgeoning area of global health. Surgeons can engage in one-or many-of the facets of global healthcare delivery: clinical care, capacity building, education, research, etc. Working in an increasingly global community, surgeons must be aware of the richness of cultural diversity at home and around the world such that they can provide culturally sensitive care. This chapter focuses on the most common way in which surgeons engage in global surgery: surgical short-term experiences in global health (STEGHs). Surgical STEGHs pose an intricate set of ethical dilemmas. As team leaders, surgeons must understand the community they intend to serve on these trips. Further, they should confirm that everyone who joins them is prepared to deliver care in a culturally sensitive and competent manner. Finally, surgeons must consider potential ethical dilemmas that may arise before, during, and after surgical STEGHs and have strategies to navigate them.
Language	English
Publishing date	2022-09-13
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2048635-2
ISSN	1531-0043
ISSN	1531-0043
DOI	10.1055/s-0042-1746186
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Article: Presence of Polyketide Synthase (PKS) Gene and Counterpart Virulence Determinants in

Kaur, Christina Parvinder / Iyadorai, Thevambiga / Sears, Cynthia / Roslani, April Camilla / Vadivelu, Jamuna / Samudi, Chandramathi

Microorganisms

2023 Volume 11, Issue 2

Abstract: Klebsiella ... ...

Abstract	Klebsiella pneumoniae
Language	English
Publishing date	2023-02-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms11020443
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Article: Cultural Sensitivity and Ethical Considerations

Bobel, Matthew Cronon / Al Hinai, Alreem / Roslani, April Camilla

Clinics in Colon and Rectal Surgery

(Diagnosis and Surgical Management of Colorectal Disorders in Resource-Limited Settings)

2022 Volume 35, Issue 05, Page(s) 371–375

Abstract: Global surgery is a burgeoning area of global health. Surgeons can engage in one–or many–of the facets of global healthcare delivery: clinical care, capacity building, education, research, etc. Working in an increasingly global community, surgeons must ... ...

Series title	Diagnosis and Surgical Management of Colorectal Disorders in Resource-Limited Settings
Abstract	Global surgery is a burgeoning area of global health. Surgeons can engage in one–or many–of the facets of global healthcare delivery: clinical care, capacity building, education, research, etc. Working in an increasingly global community, surgeons must be aware of the richness of cultural diversity at home and around the world such that they can provide culturally sensitive care. This chapter focuses on the most common way in which surgeons engage in global surgery: surgical short-term experiences in global health (STEGHs). Surgical STEGHs pose an intricate set of ethical dilemmas. As team leaders, surgeons must understand the community they intend to serve on these trips. Further, they should confirm that everyone who joins them is prepared to deliver care in a culturally sensitive and competent manner. Finally, surgeons must consider potential ethical dilemmas that may arise before, during, and after surgical STEGHs and have strategies to navigate them.
Keywords	global surgery ethics ; cultural sensitivity ; cultural competency ; global health
Language	English
Publishing date	2022-09-01
Publisher	Thieme Medical Publishers, Inc.
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	2048635-2
ISSN	1530-9681 ; 1531-0043
ISSN (online)	1530-9681
ISSN	1531-0043
DOI	10.1055/s-0042-1746186
Database	Thieme publisher's database

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Article ; Online: Evaluating the ability of the Sodergren score to guide the management of internal haemorrhoidal disease.

Sha, H L / Roslani, A C / Poh, K S

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

2020 Volume 22, Issue 10, Page(s) 1379–1387

Abstract: Aim: The Sodergren score was developed to objectively measure the severity of haemorrhoidal symptoms. This study aimed to determine if there was a difference in the Sodergren score between patients who were offered surgery and patients who underwent ... ...

Abstract	Aim: The Sodergren score was developed to objectively measure the severity of haemorrhoidal symptoms. This study aimed to determine if there was a difference in the Sodergren score between patients who were offered surgery and patients who underwent successful rubber band ligation of internal haemorrhoidal disease and to assess its performance in guiding management. Method: This is a prospective, observational study. The preintervention Sodergren scores of subjects with internal haemorrhoidal disease were recorded and blinded to the surgeon in charge. Sodergren scores of subjects in the two arms were unblinded and compared at the end of the study. Results: The results for 290 patients were available for final analysis. The median scores of those offered surgery and those who underwent successful rubber band ligation differed significantly [4 (interquartile range 3-10) vs 0 (interquartile range 0-4), P = 0.001]. In predicting treatment, the Sodergren score had an area under the receiver operating characteristic curve of 0.735 (95% CI 0.675-0.795). Conclusion: There is a significant difference in scores between patients who were offered surgery and patients with successful rubber band ligation. Our study suggests that the Sodergren score has an acceptable discrimination in predicting the need for surgery in internal haemorrhoidal disease. We propose that patients with a Sodergren score of 6 or more be considered for upfront surgery. This score could potentially be used to standardize outcomes of future haemorrhoid trials.
MeSH term(s)	Hemorrhoids/surgery ; Humans ; Ligation ; Prospective Studies ; ROC Curve
Language	English
Publishing date	2020-05-15
Publishing country	England
Document type	Journal Article ; Observational Study
ZDB-ID	1440017-0
ISSN	1463-1318 ; 1462-8910
ISSN (online)	1463-1318
ISSN	1462-8910
DOI	10.1111/codi.15091
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Article ; Online: Low Acceptance of Surgery Results in High Morbidity and Mortality Among Asian Patients With IBD.

Rajaram, Ruveena B / Hilmi, Ida N / Roslani, April C

Diseases of the colon and rectum

2020 Volume 63, Issue 4, Page(s) 415–417

MeSH term(s)	Asia/epidemiology ; Humans ; Inflammatory Bowel Diseases/epidemiology ; Inflammatory Bowel Diseases/surgery ; Morbidity/trends ; Patient Acceptance of Health Care/statistics & numerical data ; Survival Rate/trends
Language	English
Publishing date	2020-03-01
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	212581-x
ISSN	1530-0358 ; 0012-3706
ISSN (online)	1530-0358
ISSN	0012-3706
DOI	10.1097/DCR.0000000000001606
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Article: Pathological Complete Response After Neoadjuvant Therapy in Rectal Adenocarcinoma: a 5-Year Follow-up.

Leow, Yeen Chin / Roslani, April Camilla / Xavier, Ruben Gregory / Lee, Fei Yee

The Indian journal of surgery

2021 Volume 83, Issue Suppl 3, Page(s) 768–775

Abstract: Neoadjuvant therapy is the gold standard treatment of locally advanced rectal cancer. It may induce complete sterilization of tumor cell and decreases its local recurrence rate. While 15-20% of patients were found to have pathological complete response ( ... ...

Abstract	Neoadjuvant therapy is the gold standard treatment of locally advanced rectal cancer. It may induce complete sterilization of tumor cell and decreases its local recurrence rate. While 15-20% of patients were found to have pathological complete response (pCR) with combined multimodal therapy, Asian data were generally scarce. pCR rate can indicate the suitability of applying the "watch-and-wait" strategy, which advocates deferment of surgery that can alleviate surgery-associated morbidity.To determine the percentage of pCR of rectal cancer after neoadjuvant therapy. Patients diagnosed with rectal cancer underwent treatment from 2013 to 2017 were retrieved retrospectively. Demographic data, tumor localization, pre- and post-operative pathological reports, neoadjuvant therapy, and pCR status were collected from patients' records. A total of 242 out of 259 patients were treated with definitive rectal surgery. Mean age was 67.1 years old. Chinese ethnicity and male gender were predominant (n = 131, 54.1% and n = 146, 64.3% respectively). More than half (n = 124, 51.2%) had tumor located at mid or low rectum. Histologically, moderate differentiated adenocarcinoma was predominant (n = 227, 93.8%). Merely half (n = 123, 50.8%) of the patients received neoadjuvant chemoradiation therapy, but only 12 (9.8%) had a pCR. From follow-up on these 12 pCR patients, most had 2-year disease-free survival but 1 (8.3%) of the pCR had distant metastasis within 1-year post-surgery. The pathological complete response rate in our center was lower than reported. Stringent patient selection with close follow-up for patients should be carried out if the "watch-and-wait" strategy is implemented in our population.
Language	English
Publishing date	2021-05-27
Publishing country	India
Document type	Journal Article
ZDB-ID	138063-1
ISSN	0972-2068 ; 0019-5650
ISSN	0972-2068 ; 0019-5650
DOI	10.1007/s12262-021-02945-5
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Article: Determinants of Household Catastrophic Health Expenditure: A Systematic Review.

Azzani, Meram / Roslani, April Camilla / Su, Tin Tin

The Malaysian journal of medical sciences : MJMS

2019 Volume 26, Issue 1, Page(s) 15–43

Abstract: The World Health Organization estimates that annually 150 million people experience severe (catastrophic) financial difficulties as a result of healthcare payments. Therefore, a systematic review was carried out to identify the determinants of household ... ...

Abstract	The World Health Organization estimates that annually 150 million people experience severe (catastrophic) financial difficulties as a result of healthcare payments. Therefore, a systematic review was carried out to identify the determinants of household catastrophic health expenditure (CHE) in low-to high-income countries around the world. Both electronic and manual searches were conducted. The main outcome of interest was the determinants of CHE due to healthcare payments. Thirty eight studies met the inclusion criteria for review. The analysis revealed that household economic status, incidence of hospitalisation, presence of an elderly or disabled household member in the family, and presence of a family member with a chronic illness were the common significant factors associated with household CHE. The crucial finding of the current study is that socioeconomic inequality plays an important role in the incidence of CHE all over the world, where low-income households are at high risk of financial hardship from healthcare payments. This suggests that healthcare financing policies should be revised in order to narrow the gap in socioeconomic inequality and social safety nets should be implemented and strengthened for people who have a high need for health care.
Language	English
Publishing date	2019-02-28
Publishing country	Malaysia
Document type	Journal Article ; Review
ZDB-ID	2197205-9
ISSN	2180-4303 ; 1394-195X
ISSN (online)	2180-4303
ISSN	1394-195X
DOI	10.21315/mjms2019.26.1.3
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