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  1. Article ; Online: Editorial of special focus on melanoma immunotherapy.

    Rossi, Ernesto

    Human vaccines & immunotherapeutics

    2022  Volume 18, Issue 3, Page(s) 2030170

    MeSH term(s) Humans ; Immunotherapy ; Melanoma/therapy
    Language English
    Publishing date 2022-05-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2664176-8
    ISSN 2164-554X ; 2164-5515
    ISSN (online) 2164-554X
    ISSN 2164-5515
    DOI 10.1080/21645515.2022.2030170
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6967: Show issues Location:
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  2. Article: Editorial: Non-cutaneous melanoma: new therapeutic insights.

    Rossi, Ernesto / Carvajal, Richard D

    Frontiers in oncology

    2024  Volume 13, Page(s) 1362238

    Language English
    Publishing date 2024-01-17
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1362238
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  3. Article ; Online: The Social Construction of Gender in Medical Interactions: A Case for the Perpetuation of Stereotypes?

    Rossi, Elisa

    Health communication

    2020  Volume 36, Issue 9, Page(s) 1125–1135

    Abstract: This paper focuses on the ways in which gender, conceived as the product of an ongoing social and cultural construction in and through communication processes, is accomplished during medical encounters and through the narratives produced within these ... ...

    Abstract This paper focuses on the ways in which gender, conceived as the product of an ongoing social and cultural construction in and through communication processes, is accomplished during medical encounters and through the narratives produced within these interactions. The main objective is to examine: (1) when and by what devices gender becomes interactionally relevant; (2) the participants' narratives on 'gender issues'; (3) the interplay between the narratives produced and the forms of communication created, also considering which form may be more effective in challenging gender stereotypes and bias. Data are drawn from a corpus of self-administered audio-recorded interactions between a female gynecologist/midwife and pregnant patients. The consultations (half of them mediated, half not) took place in a city of North Italy; the patients (sometimes accompanied by the husband) are migrant women from North and West Africa. The main results show that: (1) at each stage of the examinations, an orientation to gender emerges, mainly through questions that display categorizations, category-bound activities, and cultural assumptions about gender: when referred to the patient, these devices often reproduce the traditional cultural model of femininity and, connected to this, the 'normal' (heterosexual and stable) intimate relationship as socially expected; (2) medical dialogue as patient-centered approach is the most recurrent form of interaction and often leads to a co-construction of narratives in which personal uniqueness is more relevant than gender roles, expectations, and stereotyped representations; when husbands are involved, however, the interactions seem to shift toward doctor-centered forms of communication, and this usually leads to asymmetrical and directive constructions of narratives about differentiated and traditional gender roles.
    MeSH term(s) Communication ; Female ; Humans ; Narration ; Pregnancy ; Sexual Partners ; Stereotyping ; Transients and Migrants
    Language English
    Publishing date 2020-03-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 1038723-7
    ISSN 1532-7027 ; 1041-0236
    ISSN (online) 1532-7027
    ISSN 1041-0236
    DOI 10.1080/10410236.2020.1735698
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    Zs.A 2769: Show issues Location:
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  4. Article ; Online: Immunoterapia per melanoma metastatico con mutazione di BRAF.

    Rossi, Ernesto

    Recenti progressi in medicina

    2020  Volume 111, Issue 12, Page(s) 48e–53e

    Abstract: The treatment of cutaneous melanoma harboring BRAF mutation has been greatly enriched. BRAF/MEK inhibitors can improve the outcome of patients with this disease. On the other hand, immunotherapy can also be effective. A focus on the role of immune ... ...

    Title translation Immunotherapy for BRAF mutant metastatic melanoma.
    Abstract The treatment of cutaneous melanoma harboring BRAF mutation has been greatly enriched. BRAF/MEK inhibitors can improve the outcome of patients with this disease. On the other hand, immunotherapy can also be effective. A focus on the role of immune checkpoint inhibitors in advanced melanoma with BRAF mutation has been performed.
    MeSH term(s) Humans ; Immunologic Factors ; Immunotherapy ; Melanoma/genetics ; Melanoma/therapy ; Mutation ; Protein Kinase Inhibitors/therapeutic use ; Proto-Oncogene Proteins B-raf/genetics ; Skin Neoplasms/genetics ; Skin Neoplasms/therapy
    Chemical Substances Immunologic Factors ; Protein Kinase Inhibitors ; BRAF protein, human (EC 2.7.11.1) ; Proto-Oncogene Proteins B-raf (EC 2.7.11.1)
    Language Italian
    Publishing date 2020-12-27
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 138266-4
    ISSN 2038-1840 ; 0034-1193
    ISSN (online) 2038-1840
    ISSN 0034-1193
    DOI 10.1701/3509.34976
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    Zs.B 193: Show issues Location:
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  5. Article ; Online: Novel vascular roles of human endoglin in pathophysiology.

    Rossi, Elisa / Bernabeu, Carmelo

    Journal of thrombosis and haemostasis : JTH

    2023  Volume 21, Issue 9, Page(s) 2327–2338

    Abstract: Endoglin, alias CD105, is a human membrane glycoprotein highly expressed in vascular endothelial cells. It is involved in angiogenesis and angiogenesis-related diseases, including the rare vascular pathology known as hereditary hemorrhagic telangiectasia ...

    Abstract Endoglin, alias CD105, is a human membrane glycoprotein highly expressed in vascular endothelial cells. It is involved in angiogenesis and angiogenesis-related diseases, including the rare vascular pathology known as hereditary hemorrhagic telangiectasia type 1. Although endoglin acts as an accessory receptor for members of the transforming growth factor-β family, in recent years, emerging evidence has shown a novel functional role for this protein beyond the transforming growth factor-β system. In fact, endoglin has been found to be an integrin counterreceptor involved in endothelial cell adhesion processes during pathological inflammatory conditions and primary hemostasis. Furthermore, a circulating form of endoglin, also named as soluble endoglin, whose levels are abnormally increased in different pathological conditions, such as preeclampsia, seems to act as an antagonist of membrane-bound endoglin and as a competitor of the fibrinogen-integrin interaction in platelet-dependent thrombus formation. These studies suggest that membrane-bound endoglin and circulating endoglin are important components involved in vascular homeostasis and hemostasis.
    MeSH term(s) Female ; Humans ; Pregnancy ; Antigens, CD/metabolism ; Endoglin/metabolism ; Endothelial Cells/metabolism ; Integrins/metabolism ; Receptors, Cell Surface/metabolism ; Telangiectasia, Hereditary Hemorrhagic ; Transforming Growth Factor beta/metabolism ; Transforming Growth Factors/metabolism ; Vascular Cell Adhesion Molecule-1/metabolism
    Chemical Substances Antigens, CD ; Endoglin ; Integrins ; Receptors, Cell Surface ; Transforming Growth Factor beta ; Transforming Growth Factors (76057-06-2) ; Vascular Cell Adhesion Molecule-1
    Language English
    Publishing date 2023-06-12
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1016/j.jtha.2023.06.007
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    Zs.MO 295: Show issues

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  6. Article ; Online: Music Therapy as a Complementary Treatment in Patients with Dementia Associated to Alzheimer's Disease: A Systematic Review.

    Rossi, Eleonora / Marrosu, Francesco / Saba, Luca

    Journal of Alzheimer's disease : JAD

    2024  Volume 98, Issue 1, Page(s) 33–51

    Abstract: Background: Alzheimer's disease (AD) is a complex condition that affects various aspects of a patient's life. Music therapy may be considered a beneficial supplementary tool to traditional therapies, that not fully address the range of AD manifestations. ...

    Abstract Background: Alzheimer's disease (AD) is a complex condition that affects various aspects of a patient's life. Music therapy may be considered a beneficial supplementary tool to traditional therapies, that not fully address the range of AD manifestations.
    Objective: The purpose of this systematic review is to investigate whether music therapy can have a positive impact on AD patients and on which symptoms.
    Methods: The main research databases employed have been PubMed and Cochrane, using the keywords "dementia", "music therapy", "Alzheimer", "fMRI", "music", and "EEG".
    Results: After removing duplicates and irrelevant studies, 23 were screened using set criteria, resulting in the final inclusion of 15 studies. The total number of participants included in these studies has been of 1,196 patients. For the fMRI analysis the search resulted in 28 studies on PubMed, two of which were included in the research; the total number of participants was of 124 individuals. The studies conducted with EEG were found using PubMed. The initial search resulted in 15 studies, but after a more accurate evaluation only 2 have been included in the analysis.
    Conclusions: Even though the data currently available is not sufficient to draw conclusions supported by robust statistical power, the impact of music therapy on AD neuropsychiatric symptoms deserves great interest. Further research should be ushered, possibly multicentric studies, led with neuroimaging and other recent techniques, which can eventually open views on the music role in improving the cognitive status in AD.
    MeSH term(s) Humans ; Alzheimer Disease/complications ; Alzheimer Disease/diagnostic imaging ; Alzheimer Disease/therapy ; Music Therapy
    Language English
    Publishing date 2024-03-01
    Publishing country Netherlands
    Document type Journal Article ; Systematic Review
    ZDB-ID 1440127-7
    ISSN 1875-8908 ; 1387-2877
    ISSN (online) 1875-8908
    ISSN 1387-2877
    DOI 10.3233/JAD-230852
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    Zs.A 6084: Show issues Location:
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  7. Article ; Online: An evolution in sentinel node mapping for cervical cancer.

    Rossi, E C

    BJOG : an international journal of obstetrics and gynaecology

    2020  Volume 128, Issue 5, Page(s) 899

    MeSH term(s) Carbon ; Female ; Humans ; Nanoparticles ; Prospective Studies ; Sentinel Lymph Node Biopsy ; Uterine Cervical Neoplasms/surgery
    Chemical Substances Carbon (7440-44-0)
    Language English
    Publishing date 2020-12-28
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2000931-8
    ISSN 1471-0528 ; 0306-5456 ; 1470-0328
    ISSN (online) 1471-0528
    ISSN 0306-5456 ; 1470-0328
    DOI 10.1111/1471-0528.16568
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  8. Article ; Online: Dried water-redispersible bacterial nanocellulose with sorbitol as capping agent

    Rossi, E. / Salvay, A.G. / Errea, M.I. / Foresti, M.L.

    Food Hydrocolloids. 2023 May 25, p.108916-

    2023  , Page(s) 108916–

    Abstract: In view of the economic and technical limitations associated with diluted aqueous suspensions of cellulose nanofibrils, in the present contribution sorbitol was assayed as capping agent in the drying of bacterial nanocellulose (BNC) for the first time. ... ...

    Abstract In view of the economic and technical limitations associated with diluted aqueous suspensions of cellulose nanofibrils, in the present contribution sorbitol was assayed as capping agent in the drying of bacterial nanocellulose (BNC) for the first time. The effect of different sorbitol:BNC mass ratios (1:1, 3:1 and 5:1), drying strategies (freeze-drying versus oven-drying), and redispersion methods (high-speed homogenization and mechanical stirring) on the water redispersibility of dried BNC was studied. Sedimentation, specific surface area and rheology assays all demonstrated the suitability of sorbitol for significantly limiting irreversible hydrogen bonding between adjacent cellulose nanofibrils during dehydration, leading to redispersed BNC suspensions with characteristics similar to those of never-dried ones. In the case of freeze-dried samples, results showed that the lowest sorbitol:BNC mass ratio assayed (i.e., 1:1) was enough to prevent irreversible hydrogen bonding between adjacent cellulose fibrils, whereas for oven-dried BNC samples full redispersion was achieved by mechanical stirring when sorbitol:BNC mass ratios of at least 3:1 were used. The feasibility of easily removing sorbitol from the dried product upon redispersion was also verified.
    Keywords cellulose ; cellulose fibrils ; cellulose nanofibers ; freeze drying ; homogenization ; hydrocolloids ; hydrogen ; rheology ; sorbitol ; surface area ; Bacterial nanocellulose ; Drying ; Hornification ; Redispersion
    Language English
    Dates of publication 2023-0525
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Pre-press version
    ZDB-ID 742742-6
    ISSN 1873-7137 ; 0268-005X
    ISSN (online) 1873-7137
    ISSN 0268-005X
    DOI 10.1016/j.foodhyd.2023.108916
    Database NAL-Catalogue (AGRICOLA)

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    Z 4414: Show issues

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  9. Article ; Online: Analysis of District Heating Networks

    Borsche, R. / Eimer, Matthias / Garavello, M. / Rossi, E.

    2023  

    Abstract: In the context of district heating networks we consider a model for the distribution of energy through water (for heating or cooling) from a central power station to the consumers. We prove the well posedness of the system, by using the Banach Fixed ... ...

    Abstract In the context of district heating networks we consider a model for the distribution of energy through water (for heating or cooling) from a central power station to the consumers. We prove the well posedness of the system, by using the Banach Fixed Point Theorem together with stability estimates for reduced systems. Eventually we consider optimal control problems motivated by applications and we provide the existence of optimal controls in special situations.

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    Keywords District heating networks ; Mixed ODE–PDE system ; Control problems ; DDC::500 Naturwissenschaften und Mathematik
    Language English
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Bei Bauchschmerzen im Alter: Auch an eine Appendizitis denken!

    Rossi, Elena / Imdahl, Andreas

    MMW Fortschritte der Medizin

    2022  Volume 164, Issue 2, Page(s) 44–45

    Title translation Appendicitis in the elderly - a challenge.
    MeSH term(s) Acute Disease ; Age Factors ; Aged ; Appendectomy ; Appendicitis ; Humans ; Retrospective Studies
    Language German
    Publishing date 2022-01-28
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1478211-x
    ISSN 1613-3560 ; 1438-3276
    ISSN (online) 1613-3560
    ISSN 1438-3276
    DOI 10.1007/s15006-021-0572-6
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