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  1. Article: Neuroendocrine liver metastases treatment strategies: a viewpoint.

    Rossi, Roberta Elisa

    Hepatobiliary surgery and nutrition

    2021  Volume 10, Issue 4, Page(s) 561–563

    Language English
    Publishing date 2021-08-21
    Publishing country China (Republic : 1949- )
    Document type Editorial ; Comment
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn-21-178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: NEN Gain or NEN Loss: Endoscopic Resection for Rectal Neuroendocrine Neoplasms < 15 mm.

    Rossi, Roberta Elisa / Massironi, Sara

    Digestive diseases and sciences

    2023  Volume 68, Issue 7, Page(s) 2793–2795

    MeSH term(s) Humans ; Neuroendocrine Tumors/surgery ; Rectal Neoplasms/surgery ; Endoscopy ; Retrospective Studies ; Pancreatic Neoplasms ; Stomach Neoplasms
    Language English
    Publishing date 2023-05-22
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 304250-9
    ISSN 1573-2568 ; 0163-2116
    ISSN (online) 1573-2568
    ISSN 0163-2116
    DOI 10.1007/s10620-023-07927-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The Increasing Incidence of Neuroendocrine Neoplasms Worldwide: Current Knowledge and Open Issues.

    Rossi, Roberta Elisa / Massironi, Sara

    Journal of clinical medicine

    2022  Volume 11, Issue 13

    Abstract: Neuroendocrine neoplasms (NENs) include a heterogeneous group of tumors derived from neuroendocrine cells, most commonly arising from the gastro-entero-pancreatic (GEP) and bronchopulmonary tracts [ ... ]. ...

    Abstract Neuroendocrine neoplasms (NENs) include a heterogeneous group of tumors derived from neuroendocrine cells, most commonly arising from the gastro-entero-pancreatic (GEP) and bronchopulmonary tracts [...].
    Language English
    Publishing date 2022-06-30
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11133794
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Interaction between Gut Microbiota and Celiac Disease: From Pathogenesis to Treatment.

    Rossi, Roberta Elisa / Dispinzieri, Giulia / Elvevi, Alessandra / Massironi, Sara

    Cells

    2023  Volume 12, Issue 6

    Abstract: Celiac disease (CD) is a common systemic disorder that results from an abnormal response of human immunity to gluten intake, affecting the small intestine. In individuals who carry a genetic susceptibility, CD is triggered by environmental factors, ... ...

    Abstract Celiac disease (CD) is a common systemic disorder that results from an abnormal response of human immunity to gluten intake, affecting the small intestine. In individuals who carry a genetic susceptibility, CD is triggered by environmental factors, including viral infections and dysbiosis of the gut microbiota. The gut microbiome is essential in controlling the immune system, and recent findings indicate that changes in the gut microbiome may contribute to various chronic immune disorders, such as CD through mechanisms that still require further exploration. Some bacteria exhibit epitopes that mimic gliadin and may enhance an immune response in the host. Other bacteria, including
    MeSH term(s) Infant ; Humans ; Celiac Disease/genetics ; Gastrointestinal Microbiome/physiology ; Glutens ; Gliadin ; Bacteria/metabolism ; Inflammation
    Chemical Substances Glutens (8002-80-0) ; Gliadin (9007-90-3)
    Language English
    Publishing date 2023-03-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells12060823
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The Role of Diet and Supplements in the Prevention and Progression of COVID-19: Current Knowledge and Open Issues.

    Rossi, Roberta Elisa / Chen, Jie / Caplin, Martyn Evan

    Preventive nutrition and food science

    2022  Volume 27, Issue 2, Page(s) 137–149

    Abstract: A healthy diet and dietary supplements have gained attention as potential co-adjuvants in managing and preventing coronavirus disease 2019 (COVID-19). This paper critically reviews the current evidence regarding the impact of diet and supplements on the ... ...

    Abstract A healthy diet and dietary supplements have gained attention as potential co-adjuvants in managing and preventing coronavirus disease 2019 (COVID-19). This paper critically reviews the current evidence regarding the impact of diet and supplements on the prevention and progression of COVID-19. According to available data, a healthy diet and normal weight are considered protective factors. Regarding dietary supplementation, the most robust results from human studies are for vitamin C, which appears to decrease inflammatory markers and suppress cytokine storm. A small, randomized trial showed that a high dose of vitamin D significantly reduced the need for intensive care unit treatment of patients requiring hospitalization for COVID-19. According to retrospective human studies, there is limited evidence for vitamin E and selenium supplements. Animal studies have investigated the effects of green tea and curcumin. Xanthohumol and probiotics, interesting for their antiviral, anti-inflammatory, and immunoregulatory properties, need formal clinical study. In summary, there is promising evidence supporting the role of diet and supplements as co-adjuvants in the treatment of COVID-19. Further studies and properly designed clinical trials are necessary to draw more robust conclusions; however, it is not unreasonable to take a pragmatic approach and promote the use of appropriate diet and supplements to counter the effects of COVID-19, ideally with a mechanism to assess outcomes.
    Language English
    Publishing date 2022-07-29
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 2668373-8
    ISSN 2287-8602 ; 2287-1098
    ISSN (online) 2287-8602
    ISSN 2287-1098
    DOI 10.3746/pnf.2022.27.2.137
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Reply.

    Rossi, Roberta Elisa / Massironi, Sara

    Pancreas

    2020  Volume 49, Issue 9, Page(s) e81–e82

    MeSH term(s) Chromogranin A ; Diagnostic Tests, Routine ; Follow-Up Studies ; Gastrointestinal Neoplasms ; Humans ; Neuroendocrine Tumors
    Chemical Substances Chromogranin A
    Keywords covid19
    Language English
    Publishing date 2020-09-28
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 632831-3
    ISSN 1536-4828 ; 0885-3177
    ISSN (online) 1536-4828
    ISSN 0885-3177
    DOI 10.1097/MPA.0000000000001639
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Intraductal papillary mucinous neoplasms of the pancreas: a clinical challenge.

    Rossi, Roberta Elisa / Massironi, Sara

    Expert review of gastroenterology & hepatology

    2018  Volume 12, Issue 11, Page(s) 1123–1133

    Abstract: Introduction: The incidental detection rate of intraductal papillary mucinous neoplasms (IPMNs) has significantly increased. However, little is known about the natural history of these tumors. Their optimal management and appropriate follow-up are still ...

    Abstract Introduction: The incidental detection rate of intraductal papillary mucinous neoplasms (IPMNs) has significantly increased. However, little is known about the natural history of these tumors. Their optimal management and appropriate follow-up are still unclear. We have, therefore, reviewed the available literature on IPMN focusing on their diagnosis, treatment according to the risk of malignant transformation, and follow-up. Areas covered: Bibliographical searches were performed in PubMed for the terms 'intraductal papillary mucinous neoplasm' and 'natural history' and 'diagnosis' and 'treatment' and 'surgery' and 'follow-up' and 'prognosis.' PubMed was used to search for all the relevant articles published over the last 10 years. A total of 7244 records were identified. After filtering for year range, English language, human studies, article types, and removing duplicates, 74 articles were left with the strongest level of evidence. Expert commentary: Available guidelines for IPMN management are mainly based on expert opinions and may lack strong evidence. Further studies are warranted to better predict the risk of recurrence/future malignancy and to establish standardized guidelines. IPMNs management should be based on multidisciplinary discussion and treatment should be tailored to an individual patient according to patient and tumor characteristics.
    MeSH term(s) Adult ; Aged ; Biopsy ; Diagnosis, Differential ; Disease Progression ; Female ; Humans ; Male ; Middle Aged ; Pancreatic Intraductal Neoplasms/diagnostic imaging ; Pancreatic Intraductal Neoplasms/epidemiology ; Pancreatic Intraductal Neoplasms/pathology ; Pancreatic Intraductal Neoplasms/therapy ; Predictive Value of Tests ; Risk Factors ; Treatment Outcome ; Young Adult
    Language English
    Publishing date 2018-10-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2481021-6
    ISSN 1747-4132 ; 1747-4124
    ISSN (online) 1747-4132
    ISSN 1747-4124
    DOI 10.1080/17474124.2018.1530111
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: ASO Author Reflections: Heterogeneity of Duodenal Neuroendocrine Tumors.

    Massironi, Sara / Rossi, Roberta Elisa

    Annals of surgical oncology

    2018  Volume 25, Issue Suppl 3, Page(s) 858–859

    MeSH term(s) Duodenal Neoplasms ; Humans ; Intestinal Neoplasms ; Neuroendocrine Tumors ; Pancreatic Neoplasms ; Stomach Neoplasms
    Language English
    Publishing date 2018-08-25
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-018-6713-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Edoxaban for the treatment of cancer associated venous thromboembolism as an alternative to low-molecular-weight-heparin.

    Fiorelli, Elisa Maria / Rossi, Roberta Elisa

    Internal and emergency medicine

    2018  Volume 13, Issue 7, Page(s) 1089–1091

    MeSH term(s) Anticoagulants ; Heparin ; Heparin, Low-Molecular-Weight ; Humans ; Pyridines ; Thiazoles ; Venous Thromboembolism ; Venous Thrombosis
    Chemical Substances Anticoagulants ; Heparin, Low-Molecular-Weight ; Pyridines ; Thiazoles ; Heparin (9005-49-6) ; edoxaban (NDU3J18APO)
    Language English
    Publishing date 2018-06-12
    Publishing country Italy
    Document type Journal Article ; Comment
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-018-1886-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Endoscopic techniques for diagnosis and treatment of gastro-entero-pancreatic neuroendocrine neoplasms: Where we are.

    Rossi, Roberta Elisa / Elvevi, Alessandra / Gallo, Camilla / Palermo, Andrea / Invernizzi, Pietro / Massironi, Sara

    World journal of gastroenterology

    2022  Volume 28, Issue 26, Page(s) 3258–3273

    Abstract: Background: The correct localization of the primary tumor site and a complete histological diagnosis represent the milestones for the proper management of gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NENs).: Aim: To analyze current evidence ...

    Abstract Background: The correct localization of the primary tumor site and a complete histological diagnosis represent the milestones for the proper management of gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NENs).
    Aim: To analyze current evidence on the role of endoscopy in the diagnosis/treatment of GEP-NENs.
    Methods: An extensive bibliographical search was performed in PubMed to identify guidelines and primary literature (retrospective and prospective studies, systematic reviews, case series) published in the last 15 years, using both medical subject heading (MeSH) terms and free-language keywords: gastro-entero-pancreatic neuroendocrine neoplasms; endoscopy; ultrasound endoscopy; capsule endoscopy; double-balloon enteroscopy; diagnosis; therapy; staging.
    Results: In the diagnostic setting, endoscopic ultrasonography (EUS) represents the diagnostic gold standard for pancreatic NENs and the technique of choice for the locoregional staging of gastric, duodenal and rectal NENs. The diagnosis of small bowel NENs (sbNENs) has been improved with the advent of video capsule endoscopy and double-balloon enteroscopy, which allow for direct visualization of the entire small bowel; however, data regarding the efficacy/safety of these techniques in the detection of sbNENs are scanty and often inconclusive. From a therapeutic point of view, endoscopic removal is the treatment of choice for the majority of gastric NENs (type 1/2), for well-differentiated localized nonmetastatic duodenal NENs < 1 cm, confined to the submucosa layer and for < 10 mm, stage T1-T2, rectal NENs. EUS-guided pancreatic locoregional ablative treatments have been proposed in recent studies with promising results in order to control symptoms or reduce tumor burden in selected patients.
    Conclusion: Standard axial endoscopy and EUS still play a pivotal role in several GEP-NENs. Advanced techniques for increasing the rate of R0 resection should be reserved for high-volume referral centers.
    MeSH term(s) Endoscopy, Gastrointestinal ; Endosonography ; Humans ; Intestinal Neoplasms/diagnostic imaging ; Intestinal Neoplasms/surgery ; Neuroendocrine Tumors/diagnostic imaging ; Neuroendocrine Tumors/surgery ; Pancreatic Neoplasms/diagnostic imaging ; Pancreatic Neoplasms/surgery ; Prospective Studies ; Retrospective Studies ; Stomach Neoplasms/pathology
    Language English
    Publishing date 2022-07-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2185929-2
    ISSN 2219-2840 ; 1007-9327
    ISSN (online) 2219-2840
    ISSN 1007-9327
    DOI 10.3748/wjg.v28.i26.3258
    Database MEDical Literature Analysis and Retrieval System OnLINE

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