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  1. Book: Imaging and visualization in ophthalmology: the posterior segment

    Rossin, Elizabeth J.

    (International ophthalmology clinics ; volume 60, number 1 (Winter 2020))

    2020  

    Author's details edited by guest editor: Elizabeth J. Rossin, MD, PhD, Joan W. Miller, MD
    Series title International ophthalmology clinics ; volume 60, number 1 (Winter 2020)
    Collection
    Language English
    Size vi, 96 Seiten, Illustrationen, Diagramme
    Publisher Lippincott Williams & Wilkins
    Publishing place Philadelphia, Pennsylvania
    Publishing country United States
    Document type Book
    HBZ-ID HT020351430
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Se 38 -60,1- verfügbar in Königswinter Königswinter

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  2. Book: Imaging and visualization in ophthalmology: the anterior segment and orbit

    Rossin, Elizabeth J.

    (International ophthalmology clinics ; volume 59, number 4 (Fall 2019))

    2019  

    Author's details edited by guest editors: Elizabeth J. Rossin, MD, PhD; Joan W. Miller, MD
    Series title International ophthalmology clinics ; volume 59, number 4 (Fall 2019)
    Collection
    Language English
    Size vi, 103 Seiten, Illustrationen
    Publisher Lippincott Williams & Wilkins
    Publishing place Philadelphia, Pennsylvania
    Publishing country United States
    Document type Book
    HBZ-ID HT021025198
    Database Catalogue ZB MED Medicine, Health

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    Se 38 -59,4- verfügbar in Königswinter Königswinter

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  3. Article ; Online: Ophthalmic Trauma-Related Instruments-Critical Tools for Winning the Case.

    Sokol, Jared T / Rossin, Elizabeth J

    International ophthalmology clinics

    2024  Volume 64, Issue 2, Page(s) 187–207

    Language English
    Publishing date 2024-03-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207382-1
    ISSN 1536-9617 ; 0020-8167
    ISSN (online) 1536-9617
    ISSN 0020-8167
    DOI 10.1097/IIO.0000000000000486
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: The Pleiotropy of Complement Factor H.

    Rossin, Elizabeth J / Sobrin, Lucia

    JAMA ophthalmology

    2023  Volume 141, Issue 8, Page(s) 745–746

    MeSH term(s) Humans ; Complement Factor H/genetics ; Phenotype ; Mutation
    Chemical Substances Complement Factor H (80295-65-4)
    Language English
    Publishing date 2023-07-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701705-9
    ISSN 2168-6173 ; 2168-6165
    ISSN (online) 2168-6173
    ISSN 2168-6165
    DOI 10.1001/jamaophthalmol.2023.2756
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Trends in Anti-Vascular Endothelial Growth Factor Original Medicare Part B Claims in the United States, 2014-2019.

    Desai, Sarishka / Sekimitsu, Sayuri / Rossin, Elizabeth J / Zebardast, Nazlee

    Ophthalmic epidemiology

    2024  , Page(s) 1–10

    Abstract: Purpose: To characterize trends in use of and expenditure for the intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) agents aflibercept, ranibizumab, and bevacizumab among the population enrolled in Original Medicare from 2014 ...

    Abstract Purpose: To characterize trends in use of and expenditure for the intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF) agents aflibercept, ranibizumab, and bevacizumab among the population enrolled in Original Medicare from 2014 to 2019.
    Methods: The Centers for Medicare and Medicaid Services Physician and Other Supplier Public Use File was used to extract Medicare Part B fee-for-service outpatient injection claims data submitted by ophthalmologists. Multivariable linear regression models were used to evaluate the association between reimbursement, ophthalmologist availability, and agent administration rate.
    Results: Between 2014 and 2019, 17,588,995 intravitreal injection claims were filed by 4218 US ophthalmologists. Medicare costs for anti-VEGF injections increased from 2.51 B USD in 2014 to 4.02 B USD in 2019. Increased state-level ophthalmologist availability and incremental increases in average reimbursement amounts were found to be significantly associated with a 6.8-fold variation in 2019 overall anti-VEGF injection rates across states.
    Conclusions: Medicare injection rates and costs for anti-VEGF injections have both increased between 2014 and 2019, largely driven by increased aflibercept use. There is a significant association between ophthalmologist availability and anti-VEGF injection rate on the state level, suggesting access to care may contribute to the observed state-level disparities in intravitreal injection rates. Further characterization of factors contributing to the state-level variation in injection rates of individual anti-VEGF agents may help inform interventions promoting equitable access to and use of these drugs.
    Language English
    Publishing date 2024-02-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1213070-9
    ISSN 1744-5086 ; 0928-6586
    ISSN (online) 1744-5086
    ISSN 0928-6586
    DOI 10.1080/09286586.2024.2310854
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4138: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Reevaluating the Risk of Serious Adverse Events of Carbonic Anhydrase Inhibitors.

    Bleicher, Isaac D / Rossin, Elizabeth J / Vavvas, Demetrios G

    JAMA ophthalmology

    2022  Volume 140, Issue 7, Page(s) 745–746

    MeSH term(s) Carbonic Anhydrase Inhibitors/adverse effects ; Humans
    Chemical Substances Carbonic Anhydrase Inhibitors
    Language English
    Publishing date 2022-05-26
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2701705-9
    ISSN 2168-6173 ; 2168-6165
    ISSN (online) 2168-6173
    ISSN 2168-6165
    DOI 10.1001/jamaophthalmol.2022.1565
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Bilateral Hemorrhages in a Premature Infant With Subarachnoid Hemorrhage: An Underrecognized Etiology.

    Rossin, Elizabeth J / Vavvas, Demetrios G

    Ophthalmic surgery, lasers & imaging retina

    2020  Volume 51, Issue 10, Page(s) 596–600

    Abstract: The authors describe an 8-day-old male infant born premature at 31 weeks and 6 days (corrected gestational age: 33 weeks) with cholestatic jaundice and cytomegalovirus (CMV) viremia found to have bilateral multilaminar hemorrhages that represented a ... ...

    Abstract The authors describe an 8-day-old male infant born premature at 31 weeks and 6 days (corrected gestational age: 33 weeks) with cholestatic jaundice and cytomegalovirus (CMV) viremia found to have bilateral multilaminar hemorrhages that represented a diagnostic challenge. Fluorescein angiography (FA) ruled out vasculitis, retinitis, and neovascular process. An extensive laboratory work-up for infectious and coagulopathic etiologies was negative other than a positive systemic viral titer for CMV, but there was no retinitis based on serial exams and FA. Magnetic resonance imaging showed a right-sided subarachnoid hemorrhage, which was felt to be parturitional and confirmed the unifying diagnosis of delivery-associated retinopathy and intracranial hemorrhages in a preterm infant, a term that has been previously described. Simultaneous subarachnoid hemorrhage and vitreoretinal hemorrhage may represent an underrecognized cause of neonatal hemorrhage in preterm infants. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:596-600.].
    MeSH term(s) Brain/diagnostic imaging ; Fluorescein Angiography ; Gestational Age ; Humans ; Infant, Newborn ; Infant, Premature ; Magnetic Resonance Imaging ; Male ; Retinal Hemorrhage/diagnosis ; Retinal Hemorrhage/etiology ; Subarachnoid Hemorrhage/complications ; Subarachnoid Hemorrhage/diagnosis
    Language English
    Publishing date 2020-11-03
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2701167-7
    ISSN 2325-8179 ; 2325-8160
    ISSN (online) 2325-8179
    ISSN 2325-8160
    DOI 10.3928/23258160-20201005-09
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    Zs.A 756: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Aflibercept for Retinopathy of Prematurity: A Systematic Review and Meta-Analysis.

    Chen, Po-Yu Jay / Rossin, Elizabeth J / Vavvas, Demetrios G

    Ophthalmic surgery, lasers & imaging retina

    2021  Volume 52, Issue 12, Page(s) 673–681

    Abstract: Background and objective: To determine the effectiveness of aflibercept in retinopathy of prematurity (ROP).: Patients and methods: We performed a systematic review and meta-analysis of proportions from the literature in PubMed and Cochrane Library ... ...

    Abstract Background and objective: To determine the effectiveness of aflibercept in retinopathy of prematurity (ROP).
    Patients and methods: We performed a systematic review and meta-analysis of proportions from the literature in PubMed and Cochrane Library using search terms related to the use of aflibercept in ROP. Studies in non-preterm infants or that did not use aflibercept as the initial treatment were excluded. Risk of bias was assessed by the ROBINS-I (Risk Of Bias in Non-randomized Studies of Interventions) tool.
    Results: We identified six case series. Collectively, 218 eyes were treated with aflibercept for ROP. We found an average 97% (95% confidence interval [CI], 93% to 99%) regression rate with aflibercept and an average 16% (95% CI, 5% to 41%) recurrence rate. With the exception of one outlier study, these numbers are similar to previous reports using anti-vascular endothelial growth factor (VEGF) agents in ROP.
    Conclusions: Aflibercept holds promise for use in ROP and has been demonstrated to be efficacious in six case series. Randomized, controlled clinical trials appear warranted to compare aflibercept with other anti-VEGF agents.
    MeSH term(s) Angiogenesis Inhibitors/therapeutic use ; Humans ; Infant ; Infant, Newborn ; Receptors, Vascular Endothelial Growth Factor/therapeutic use ; Recombinant Fusion Proteins ; Retinopathy of Prematurity/drug therapy ; Vascular Endothelial Growth Factor A
    Chemical Substances Angiogenesis Inhibitors ; Recombinant Fusion Proteins ; Vascular Endothelial Growth Factor A ; aflibercept (15C2VL427D) ; Receptors, Vascular Endothelial Growth Factor (EC 2.7.10.1)
    Language English
    Publishing date 2021-12-01
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 2701167-7
    ISSN 2325-8179 ; 2325-8160
    ISSN (online) 2325-8179
    ISSN 2325-8160
    DOI 10.3928/23258160-20211124-01
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Single-cell RNA sequencing: An overview for the ophthalmologist.

    Rossin, Elizabeth J / Sobrin, Lucia / Kim, Leo A

    Seminars in ophthalmology

    2021  Volume 36, Issue 4, Page(s) 191–197

    Abstract: Understanding the molecular composition of pathogenic tissues is a critical step in understanding the pathophysiology of disease and designing therapeutics. First described in 2009, single cell RNA sequencing (scRNAseq) is a methodology whereby thousands ...

    Abstract Understanding the molecular composition of pathogenic tissues is a critical step in understanding the pathophysiology of disease and designing therapeutics. First described in 2009, single cell RNA sequencing (scRNAseq) is a methodology whereby thousands of cells are simultaneously isolated into individual micro-environments that can be altered experimentally and the genome-wide RNA expression of each cell is captured. It has undergone significant technological improvement over the last decade and gained tremendous popularity. scRNAseq is an improvement over prior pooled RNA analyses which cannot identify the cellular composition and heterogeneity of a tissue of interest. This new approach offers new opportunity for new discovery, as tissue samples can now be sub-categorized into groups of cell types based on genome-wide gene expression in an unbiased fashion. As ophthalmologists, we are uniquely positioned to obtain pathologic samples from the eye for further study. ScRNAseq has already been applied in ophthalmology to characterize retinal tissue, and it may offer the key to understanding various pathological processes in the future.
    MeSH term(s) Humans ; Ophthalmologists ; Sequence Analysis, RNA ; Single-Cell Analysis
    Language English
    Publishing date 2021-02-26
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 632820-9
    ISSN 1744-5205 ; 0882-0538
    ISSN (online) 1744-5205
    ISSN 0882-0538
    DOI 10.1080/08820538.2021.1889615
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Bacillary Layer Detachment Associated With Endogenous Fungal Endophthalmitis.

    Cox, Jacob T / Wu, Frances / Rossin, Elizabeth J / Tang, William M / Eliott, Dean

    Journal of vitreoretinal diseases

    2022  Volume 6, Issue 4, Page(s) 316–319

    Abstract: Purpose: ...

    Abstract Purpose:
    Language English
    Publishing date 2022-07-20
    Publishing country United States
    Document type Case Reports
    ISSN 2474-1272
    ISSN (online) 2474-1272
    DOI 10.1177/24741264221101224
    Database MEDical Literature Analysis and Retrieval System OnLINE

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