LIVIVO - Search results -

Search results

Result 1 - 10 of total 300

Search options

Article ; Online: Adverse effects.

Rossini, P M

2010 Volume 161, Issue 1, Page(s) 89–90

Abstract: In medicine, an adverse effect (AE) is a harmful and undesired effect resulting from a medication or intervention and procedures. Some AEs only occur when starting, increasing or discontinuing a treatment; in this case they are a function of dosage or ... ...

Abstract	In medicine, an adverse effect (AE) is a harmful and undesired effect resulting from a medication or intervention and procedures. Some AEs only occur when starting, increasing or discontinuing a treatment; in this case they are a function of dosage or drug levels at the target organs, or they may also be caused by drug interactions. The distinction between adverse and non-adverse effects is a major undertaking when a new drug is developed and tested. Studies are used to define the dosage to be used in human testing (Phase 1) as well as to calculate the maximum admissible daily intake. Imperfections in clinical trials sometimes lead to public health disasters and the withdrawal of the drug from commerce. Surgery may have a number of undesirable or harmful after-effects. Diagnostic procedures may also have AEs, depending much on whether they are invasive, non-invasive or minimally invasive. In clinical trials, a distinction is made between AEs and Serious Adverse Events (SAEs). Generally, any event which causes death, permanent damage, birth defects, or requires hospitalization is considered an SAE.
MeSH term(s)	Clinical Trials as Topic/adverse effects ; Clinical Trials as Topic/legislation & jurisprudence ; Diagnostic Techniques and Procedures/adverse effects ; Drug-Related Side Effects and Adverse Reactions ; Humans ; Iatrogenic Disease/prevention & control ; Medication Errors/legislation & jurisprudence ; Rome ; Surgical Procedures, Operative/adverse effects ; Surgical Procedures, Operative/legislation & jurisprudence
Language	English
Publishing date	2010
Publishing country	Italy
Document type	Journal Article
ZDB-ID	123320-8
ISSN	1972-6007 ; 0009-9074
ISSN (online)	1972-6007
ISSN	0009-9074
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 98: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Tracking post-stroke recovery with magnetoencephalography.

Rossini, P M

Annals of neurology

2001 Volume 49, Issue 1, Page(s) 136

MeSH term(s)	Humans ; Magnetoencephalography ; Stroke/physiopathology ; Time Factors
Language	English
Publishing date	2001-01
Publishing country	United States
Document type	Comment ; Letter
ZDB-ID	80362-5
ISSN	1531-8249 ; 0364-5134
ISSN (online)	1531-8249
ISSN	0364-5134
DOI	10.1002/1531-8249(200101)49:1<136::aid-ana24>3.0.co;2-p
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1370: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 478: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Small-worldness characteristics and its gender relation in specific hemispheric networks.

Miraglia, F / Vecchio, F / Bramanti, P / Rossini, P M

Neuroscience

2015 Volume 310, Page(s) 1–11

Abstract: Aim of this study was to verify whether the topological organization of human brain functional networks is different for males and females in resting state EEGs. Undirected and weighted brain networks were computed by eLORETA lagged linear connectivity ... ...

Abstract	Aim of this study was to verify whether the topological organization of human brain functional networks is different for males and females in resting state EEGs. Undirected and weighted brain networks were computed by eLORETA lagged linear connectivity in 130 subjects (59 males and 71 females) within each hemisphere and in four resting state networks (Attentional Network (AN), Frontal Network (FN), Sensorimotor Network (SN), Default Mode Network (DMN)). We found that small-world (SW) architecture in the left hemisphere Frontal network presented differences in both delta and alpha band, in particular lower values in delta and higher in alpha 2 in males respect to females while in the right hemisphere differences were found in lower values of SW in males respect to females in gamma Attentional, delta Sensorimotor and delta and gamma DMNs. Gender small-worldness differences in some of resting state networks indicated that there are specific brain differences in the EEG rhythms when the brain is in the resting-state condition. These specific regions could be considered related to the functions of behavior and cognition and should be taken into account both for research on healthy and brain diseased subjects.
MeSH term(s)	Analysis of Variance ; Attention/physiology ; Brain Mapping ; Case-Control Studies ; Computer Graphics ; Electroencephalography ; Female ; Functional Laterality/physiology ; Humans ; Interpersonal Relations ; Male ; Middle Aged ; Models, Neurological ; Neural Pathways/physiology ; Rest/physiology ; Sex Characteristics
Language	English
Publishing date	2015-12-03
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	196739-3
ISSN	1873-7544 ; 0306-4522
ISSN (online)	1873-7544
ISSN	0306-4522
DOI	10.1016/j.neuroscience.2015.09.028
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1215: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Brain redundancy: responsivity or plasticity?

Rossini, P M

Annals of neurology

2000 Volume 48, Issue 1, Page(s) 128–130

MeSH term(s)	Brain/physiology ; Humans ; Neuronal Plasticity/physiology
Language	English
Publishing date	2000-07
Publishing country	United States
Document type	Comment ; Letter
ZDB-ID	80362-5
ISSN	1531-8249 ; 0364-5134
ISSN (online)	1531-8249
ISSN	0364-5134
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1370: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 478: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Is transcranial magnetic stimulation of the motor cortex a prognostic tool for motor recovery after stroke?

Rossini, P M

Stroke

2000 Volume 31, Issue 6, Page(s) 1463–1464

MeSH term(s)	Electromagnetic Phenomena/instrumentation ; Evoked Potentials, Motor ; Humans ; Motor Cortex/physiopathology ; Prognosis ; Stroke/physiopathology ; Stroke/therapy ; Treatment Outcome
Language	English
Publishing date	2000-06
Publishing country	United States
Document type	Comment ; Letter
ZDB-ID	80381-9
ISSN	1524-4628 ; 0039-2499 ; 0749-7954
ISSN (online)	1524-4628
ISSN	0039-2499 ; 0749-7954
DOI	10.1161/01.str.31.6.1457-d
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 448: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Cortical plasticity and brain computer interface.

Rossini, P M / Noris Ferilli, M A / Ferreri, F

European journal of physical and rehabilitation medicine

2012 Volume 48, Issue 2, Page(s) 307–312

Abstract: There is increasing evidence to support the concept that adult brain has the remarkable ability to plastically reorganize itself. Brain plasticity involves distinct functional and structural components and plays a crucial role in reorganizing central ... ...

Abstract	There is increasing evidence to support the concept that adult brain has the remarkable ability to plastically reorganize itself. Brain plasticity involves distinct functional and structural components and plays a crucial role in reorganizing central nervous system's networks after any lesion in order to partly or totally restore lost and/or compromised functions. The idea that a computer can decode brain electromagnetic signals to infer the intentions of a human and then enact those intentions directly through a machine is becoming a reasonable technical possibility. In neurological patients unable to move and to communicate with the external environment, technologies implementing brain-machine interfaces (BMIs) can be of valuable aid and support. The emerging possibility, through neuro-imaging advanced techniques, to clarify some crucial issues underlying brain plasticity will give the possibility to modulate these mechanisms in a BCI-oriented way. This approach may have a tremendous impact in a variety of neuropsychiatric disorders and the clinical advent of this technology will usher in a new era of restorative medicine.
MeSH term(s)	Cerebral Cortex/physiology ; Communication Aids for Disabled/utilization ; Disabled Persons/rehabilitation ; Humans ; Man-Machine Systems ; Movement/physiology ; Neuronal Plasticity/physiology ; User-Computer Interface
Language	English
Publishing date	2012-06
Publishing country	Italy
Document type	Journal Article ; Review
ZDB-ID	2426908-6
ISSN	1973-9095 ; 1973-9087
ISSN (online)	1973-9095
ISSN	1973-9087
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 1388: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Adaptive and maladaptive brain functional network reorganization after stroke in hemianopia patients

Xu, Jiahua / Schoenfeld, Mircea Ariel / Rossini, Paolo M. / Tatlisumak, Turgut / Nürnberger, Andreas / Antal, Andrea / He, Huiguang / Gao, Ying / Sabel, Bernhard A.

Brain Connectivity

An electroencephalogram-tracking study

2022 Volume 12, Issue 8, Page(s) 725–739

Abstract: Objective: Hemianopia after occipital stroke is believed to be mainly due to local damage at or near the lesion site. However, magnetic resonance imaging studies suggest functional connectivity network (FCN) reorganization also in distant brain regions. ... ...

Title translation	Adaptive und maladaptive Reorganisation der funktionellen Netzwerke des Gehirns nach Schlaganfall bei Hemianopie-Patienten: Eine Elektroenzephalogramm-Tracking-Studie. (DeepL)
Abstract	Objective: Hemianopia after occipital stroke is believed to be mainly due to local damage at or near the lesion site. However, magnetic resonance imaging studies suggest functional connectivity network (FCN) reorganization also in distant brain regions. Because it is unclear whether reorganization is adaptive or maladaptive, compensating for, or aggravating vision loss, we characterized FCNs electrophysiologically to explore local and global brain plasticity and correlated FCN reorganization with visual performance. Methods: Resting-state electroencephalography (EEG) was recorded in chronic, unilateral stroke patients and healthy age-matched controls (n = 24 each). This study was approved by the local ethics committee. The correlation of oscillating EEG activity was calculated with the imaginary part of coherence between pairs of regions of interest, and FCN graph theory metrics (degree, strength, clustering coefficient) were correlated with stimulus detection and reaction time. Results: Stroke brains showed altered FCNs in the alpha- and low beta-band in numerous occipital, temporal brain structures. On a global level, FCN had a less efficient network organization whereas on the local level node networks were reorganized especially in the intact hemisphere. Here, the occipital network was 58% more rigid (with a more "regular" network structure) whereas the temporal network was 32% more efficient (showing greater "small-worldness"), both of which correlated with worse or better visual processing, respectively. Conclusions: Occipital stroke is associated with both local and global FCN reorganization, but this can be both adaptive and maladaptive. We propose that the more "regular" FCN structure in the intact visual cortex indicates maladaptive plasticity, where less processing efficacy with reduced signal/noise ratio may cause the perceptual deficits in the intact visual field (VF). In contrast, reorganization in intact temporal brain regions is presumably adaptive, possibly supporting enhanced peripheral movement perception.
Keywords	Biological Neural Networks ; Biologische Neuronale Netze ; Brain Connectivity ; Cerebrovascular Accidents ; Hemianopia ; Hemianopsie ; Konnektivität (Gehirn) ; Neural Plasticity ; Neuronale Plastizität ; Schlaganfall ; Sehfeld ; Visual Cortex ; Visual Field ; Visueller Kortex
Language	English
Document type	Article
ZDB-ID	2609017-X
ISSN	2158-0022 ; 2158-0014
ISSN (online)	2158-0022
ISSN	2158-0014
DOI	10.1089/brain.2021.0145
Database	PSYNDEX

Order via subito

Article: N30 in PD.

Rossini, P M

Neurology

1996 Volume 47, Issue 1, Page(s) 303–4; author reply 304–6

MeSH term(s)	Brain/physiopathology ; Brain Mapping ; Electroencephalography ; Evoked Potentials, Somatosensory/physiology ; Humans ; Parkinson Disease/physiopathology
Language	English
Publishing date	1996-07
Publishing country	United States
Document type	Comment ; Letter
ZDB-ID	207147-2
ISSN	1526-632X ; 0028-3878
ISSN (online)	1526-632X
ISSN	0028-3878
DOI	10.1212/wnl.47.1.303-b
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ui II Zs.153: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MG 18: Show issues
Zs.MO 374: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Optimal integration of intraneural somatosensory feedback with visual information: a single-case study.

Risso, G / Valle, G / Iberite, F / Strauss, I / Stieglitz, T / Controzzi, M / Clemente, F / Granata, G / Rossini, P M / Micera, S / Baud-Bovy, G

Scientific reports

2019 Volume 9, Issue 1, Page(s) 7916

Abstract: Providing somatosensory feedback to amputees is a long-standing objective in prosthesis research. Recently, implantable neural interfaces have yielded promising results in this direction. There is now considerable evidence that the nervous system ... ...

Abstract	Providing somatosensory feedback to amputees is a long-standing objective in prosthesis research. Recently, implantable neural interfaces have yielded promising results in this direction. There is now considerable evidence that the nervous system integrates redundant signals optimally, weighting each signal according to its reliability. One question of interest is whether artificial sensory feedback is combined with other sensory information in a natural manner. In this single-case study, we show that an amputee with a bidirectional prosthesis integrated artificial somatosensory feedback and blurred visual information in a statistically optimal fashion when estimating the size of a hand-held object. The patient controlled the opening and closing of the prosthetic hand through surface electromyography, and received intraneural stimulation proportional to the object's size in the ulnar nerve when closing the robotic hand on the object. The intraneural stimulation elicited a vibration sensation in the phantom hand that substituted the missing haptic feedback. This result indicates that sensory substitution based on intraneural feedback can be integrated with visual feedback and make way for a promising method to investigate multimodal integration processes.
MeSH term(s)	Amputees/rehabilitation ; Artificial Limbs ; Brain-Computer Interfaces ; Electric Stimulation/instrumentation ; Electric Stimulation/methods ; Electrodes, Implanted ; Electromyography ; Feedback, Sensory/physiology ; Female ; Forearm/innervation ; Forearm/physiology ; Humans ; Middle Aged ; Single-Case Studies as Topic ; Treatment Outcome ; Ulnar Nerve/physiology
Language	English
Publishing date	2019-05-27
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-019-43815-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Characterization of multi-channel intraneural stimulation in transradial amputees.

Strauss, I / Valle, G / Artoni, F / D'Anna, E / Granata, G / Di Iorio, R / Guiraud, D / Stieglitz, T / Rossini, P M / Raspopovic, S / Petrini, F M / Micera, S

Scientific reports

2019 Volume 9, Issue 1, Page(s) 19258

Abstract: Although peripheral nerve stimulation using intraneural electrodes has been shown to be an effective and reliable solution to restore sensory feedback after hand loss, there have been no reports on the characterization of multi-channel stimulation. A ... ...

Abstract	Although peripheral nerve stimulation using intraneural electrodes has been shown to be an effective and reliable solution to restore sensory feedback after hand loss, there have been no reports on the characterization of multi-channel stimulation. A deeper understanding of how the simultaneous stimulation of multiple electrode channels affects the evoked sensations should help in improving the definition of encoding strategies for bidirectional prostheses. We characterized the sensations evoked by simultaneous stimulation of median and ulnar nerves (multi-channel configuration) in four transradial amputees who had been implanted with four TIMEs (Transverse Intrafascicular Multichannel Electrodes). The results were compared with the characterization of single-channel stimulation. The sensations were characterized in terms of location, extent, type, and intensity. Combining two or more single-channel configurations caused a linear combination of the sensation locations and types perceived with such single-channel stimulations. Interestingly, this was also true when two active sites from the same nerve were stimulated. When stimulating in multi-channel configuration, the charge needed from each electrode channel to evoke a sensation was significantly lower than the one needed in single-channel configuration (sensory facilitation). This result was also supported by electroencephalography (EEG) recordings during nerve stimulation. Somatosensory potentials evoked by multi-channel stimulation confirmed that sensations in the amputated hand were perceived by the subjects and that a perceptual sensory facilitation occurred. Our results should help the future development of more efficient bidirectional prostheses by providing guidelines for the development of more complex stimulation approaches to effectively restore multiple sensations at the same time.
MeSH term(s)	Adult ; Amputees ; Artificial Limbs ; Electroencephalography ; Female ; Humans ; Male ; Middle Aged ; Prosthesis Design ; Transcutaneous Electric Nerve Stimulation ; Ulnar Nerve/physiopathology
Language	English
Publishing date	2019-12-17
Publishing country	England
Document type	Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-019-55591-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito