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  1. Article ; Online: One hundred years of shared interest.

    Rossor, Martin

    Journal of neurology, neurosurgery, and psychiatry

    2020  Volume 91, Issue 3, Page(s) 225–226

    MeSH term(s) History, 20th Century ; History, 21st Century ; Humans ; Neurology/history ; Neurosurgery/history ; Periodicals as Topic/history ; Psychiatry/history
    Language English
    Publishing date 2020-02-10
    Publishing country England
    Document type Historical Article ; Journal Article
    ZDB-ID 3087-9
    ISSN 1468-330X ; 0022-3050
    ISSN (online) 1468-330X
    ISSN 0022-3050
    DOI 10.1136/jnnp-2019-321981
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book: Unusual dementias

    Rossor, Martin N.

    (Baillière's clinical neurology ; 1,3)

    1992  

    Author's details M. N. Rossor, guest. ed
    Series title Baillière's clinical neurology ; 1,3
    Collection
    Keywords Dementia ; Demenz ; Neurologie
    Subject Klinische Neurologie ; Anoia ; Dementia ; Chronische Verwirrtheit
    Size X S., S. 477 - 689 : Ill., graph. Darst.
    Publisher Baillière Tindall
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT004940438
    ISBN 0-7020-1631-4 ; 978-0-7020-1631-8
    Database Catalogue ZB MED Medicine, Health

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  3. Article: IN 2014 CAN WE PREVENT DEMENTIA?

    Rossor, Martin

    Transactions of the Medical Society of London

    2013  Volume 130, Page(s) 59–63

    MeSH term(s) Dementia/epidemiology ; Dementia/etiology ; Dementia/prevention & control ; Humans ; Risk Factors ; State Medicine ; United Kingdom/epidemiology
    Language English
    Publishing date 2013
    Publishing country England
    Document type Journal Article
    ZDB-ID 414727-3
    ISSN 0076-6011
    ISSN 0076-6011
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  4. Article ; Online: The link between cognitive health and neighbourhood: perceptions of the public, and of policy-makers, about problems and solutions.

    Stevens, Madeleine / Matosevic, Tihana / Suarez-Pinilla, Marta / Pais, Sarah / Rossor, Martin / Knapp, Martin

    BMC public health

    2023  Volume 23, Issue 1, Page(s) 1694

    Abstract: Background: Growing evidence indicates associations between neighbourhood-related factors such as pollution, social isolation and physical inactivity, and cognition, that is, our ability to think clearly, learn and remember. The evidence raises the ... ...

    Abstract Background: Growing evidence indicates associations between neighbourhood-related factors such as pollution, social isolation and physical inactivity, and cognition, that is, our ability to think clearly, learn and remember. The evidence raises the possibility of neighbourhood intervention playing a role in protecting population cognitive health. However, there is little understanding of these associations among the public and policy-makers, what they mean and how they might be acted on. In this study we explored perceptions of the public and policy-makers about influences of neighbourhood factors on brain functioning, and how they should inform policy.
    Methods: Qualitative methods were used in three phases; the study ran in parallel with a quantitative study looking at neighbourhood influences on cognition. In phase one, focus groups were conducted with middle-aged (40-69) members of the public to inform statistical modelling. In phase two, similar focus groups were held in four case study areas chosen based on the modelling results. In phase three, interviews with people in public health and policy roles were conducted, including people in the case study sites.
    Results: Participants described effects on their cognition from community, culture and social interactions, access to green spaces and nature, upkeep and safety of the area, and pollution, traffic and noise. Solutions included better local consultation and involvement in policy and planning, support for community interactions and active and public transport, and education on cognition. There was little awareness, but much interest, from local policy-makers and implementers, about links between cognition and place. Barriers to implementation included lack of: effective engagement with local communities, local funding and joined-up health and neighbourhood policy.
    Conclusions: People can perceive impacts of neighbourhoods on brain functioning and suggest ways local areas can be improved to support cognitive health. There is support for the idea of population-level interventions to support cognitive health.
    MeSH term(s) Middle Aged ; Humans ; Cognition ; Acceptance and Commitment Therapy ; Administrative Personnel ; Educational Status ; Policy
    Language English
    Publishing date 2023-09-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-023-16592-w
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  5. Article ; Online: The Dementia UK Ecosystem: a call to action.

    Lalli, Giovanna / Rossor, Martin / Rowe, James B / De Strooper, Bart

    The Lancet. Neurology

    2021  Volume 20, Issue 9, Page(s) 699–700

    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; Cause of Death ; Comorbidity ; Dementia/economics ; Dementia/epidemiology ; Dementia/therapy ; Humans ; Intersectoral Collaboration ; United Kingdom/epidemiology
    Language English
    Publishing date 2021-08-21
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2081241-3
    ISSN 1474-4465 ; 1474-4422
    ISSN (online) 1474-4465
    ISSN 1474-4422
    DOI 10.1016/S1474-4422(21)00246-5
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  6. Article: Genetic evidence for serum amyloid P component as a drug target for treatment of neurodegenerative disorders.

    Schmidt, A Floriaan / Finan, Chris / Chopade, Sandesh / Ellmerich, Stephan / Rossor, Martin N / Hingorani, Aroon D / Pepys, Mark B

    medRxiv : the preprint server for health sciences

    2023  

    Abstract: The direct causes of neurodegeneration underlying Alzheimer's disease (AD) and many other dementias, are not known. Here we identify serum amyloid P component (SAP), a constitutive plasma protein normally excluded from the brain, as a potential drug ... ...

    Abstract The direct causes of neurodegeneration underlying Alzheimer's disease (AD) and many other dementias, are not known. Here we identify serum amyloid P component (SAP), a constitutive plasma protein normally excluded from the brain, as a potential drug target. After meta-analysis of three genome-wide association studies, comprising 44,288 participants,
    Language English
    Publishing date 2023-08-16
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.08.15.23293564
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  7. Article ; Online: Binary reversals: a diagnostic sign in primary progressive aphasia.

    Mulroy, Eoin / Core, Lucy B / Chokesuwattanaskul, Anthipa / Johnson, Jeremy Cs / Fletcher, Phillip D / Marshall, Charles R / Volkmer, Anna / Rohrer, Jonathan D / Hardy, Chris Jd / Rossor, Martin N / Warren, Jason D

    Journal of neurology, neurosurgery, and psychiatry

    2024  Volume 95, Issue 5, Page(s) 477–480

    Abstract: Background: Binary reversals (exemplified by 'yes'/'no' confusions) have been described in patients with primary progressive aphasia (PPA) but their diagnostic value and phenotypic correlates have not been defined.: Methods: We conducted a ... ...

    Abstract Background: Binary reversals (exemplified by 'yes'/'no' confusions) have been described in patients with primary progressive aphasia (PPA) but their diagnostic value and phenotypic correlates have not been defined.
    Methods: We conducted a retrospective cohort study analysing demographic, clinical, neuropsychological, linguistic and behavioural data from patients representing all major PPA syndromes (non-fluent/agrammatic variant, nfvPPA; logopenic variant, lvPPA; semantic variant, svPPA) and behavioural variant frontotemporal dementia (bvFTD). The prevalence of binary reversals and behavioural abnormalities, illness duration, parkinsonian features and neuropsychological test scores were compared between neurodegenerative syndromes, and the diagnostic predictive value of binary reversals was assessed using logistic regression.
    Results: Data were obtained for 83 patients (21 nfvPPA, 13 lvPPA, 22 svPPA, 27 bvFTD). Binary reversals occurred in all patients with nfvPPA, but significantly less frequently and later in lvPPA (54%), svPPA (9%) and bvFTD (44%). Patients with bvFTD with binary reversals had significantly more severe language (but not general executive or behavioural) deficits than those without reversals. Controlling for potentially confounding variables, binary reversals strongly predicted a diagnosis of nfvPPA over other syndromes.
    Conclusions: Binary reversals are a sensitive (though not specific) neurolinguistic feature of nfvPPA, and should suggest this diagnosis if present as a prominent early symptom.
    MeSH term(s) Humans ; Retrospective Studies ; Frontotemporal Dementia/psychology ; Aphasia ; Language ; Aphasia, Primary Progressive/diagnosis
    Language English
    Publishing date 2024-04-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 3087-9
    ISSN 1468-330X ; 0022-3050
    ISSN (online) 1468-330X
    ISSN 0022-3050
    DOI 10.1136/jnnp-2023-331662
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  8. Article ; Online: Inspired by chance: valuing patients' informal contributions to research.

    Crutch, Sebastian / Herron, Daniel / Pickett, James / Rosser, Simon / Rossor, Martin

    BMJ (Clinical research ed.)

    2020  Volume 371, Page(s) m4478

    Language English
    Publishing date 2020-12-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.m4478
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  9. Article ; Online: The palmomental reflex: stop scratching around!

    Schott, Jonathan M / Rossor, Martin N

    Practical neurology

    2016  Volume 16, Issue 6, Page(s) 500–501

    Language English
    Publishing date 2016-11-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2170881-2
    ISSN 1474-7766 ; 1474-7758
    ISSN (online) 1474-7766
    ISSN 1474-7758
    DOI 10.1136/practneurol-2016-001509
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  10. Article ; Online: GeoSPM: Geostatistical parametric mapping for medicine.

    Engleitner, Holger / Jha, Ashwani / Pinilla, Marta Suarez / Nelson, Amy / Herron, Daniel / Rees, Geraint / Friston, Karl / Rossor, Martin / Nachev, Parashkev

    Patterns (New York, N.Y.)

    2022  Volume 3, Issue 12, Page(s) 100656

    Abstract: The characteristics and determinants of health and disease are often organized in space, reflecting our spatially extended nature. Understanding the influence of such factors requires models capable of capturing spatial relations. Drawing on statistical ... ...

    Abstract The characteristics and determinants of health and disease are often organized in space, reflecting our spatially extended nature. Understanding the influence of such factors requires models capable of capturing spatial relations. Drawing on statistical parametric mapping, a framework for topological inference well established in the realm of neuroimaging, we propose and validate an approach to the spatial analysis of diverse clinical data-GeoSPM-based on differential geometry and random field theory. We evaluate GeoSPM across an extensive array of synthetic simulations encompassing diverse spatial relationships, sampling, and corruption by noise, and demonstrate its application on large-scale data from UK Biobank. GeoSPM is readily interpretable, can be implemented with ease by non-specialists, enables flexible modeling of complex spatial relations, exhibits robustness to noise and under-sampling, offers principled criteria of statistical significance, and is through computational efficiency readily scalable to large datasets. We provide a complete, open-source software implementation.
    Language English
    Publishing date 2022-12-09
    Publishing country United States
    Document type Journal Article
    ISSN 2666-3899
    ISSN (online) 2666-3899
    DOI 10.1016/j.patter.2022.100656
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