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  1. Article ; Online: Left Ventricular Outflow Tract Obstruction After Transseptal Mitral Valve Replacement: Does HighLife Clarity Solve It?

    Keßler, Mirjam / Schneider, Leonhard-Moritz / Rottbauer, Wolfgang

    JACC. Cardiovascular interventions

    2024  Volume 17, Issue 5, Page(s) 702–703

    MeSH term(s) Humans ; Mitral Valve/diagnostic imaging ; Mitral Valve/surgery ; Ventricular Outflow Obstruction, Left ; Treatment Outcome ; Heart Valve Prosthesis Implantation/adverse effects ; Mitral Valve Insufficiency/diagnostic imaging ; Mitral Valve Insufficiency/surgery ; Ventricular Outflow Obstruction/diagnostic imaging ; Ventricular Outflow Obstruction/etiology ; Ventricular Outflow Obstruction/surgery ; Heart Valve Prosthesis ; Cardiac Catheterization/adverse effects
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2452157-7
    ISSN 1876-7605 ; 1936-8798
    ISSN (online) 1876-7605
    ISSN 1936-8798
    DOI 10.1016/j.jcin.2024.01.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Striking Variations in Aortic Valve Replacement Rates and Use of Transcatheter Aortic Valve Implantation among European Nations.

    Buckert, Dominik / Krohn-Grimberghe, Marvin / Rottbauer, Wolfgang

    Cardiology

    2023  , Page(s) 1–2

    Language English
    Publishing date 2023-11-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 80092-2
    ISSN 1421-9751 ; 0008-6312
    ISSN (online) 1421-9751
    ISSN 0008-6312
    DOI 10.1159/000534471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Comparison between a Novel Radiofrequency-Balloon and a Standard Cryo-Balloon in Pulmonary Vein Isolation: A Propensity-Score-Matched Analysis.

    Teumer, Yannick / Miesbichler, Clemens / Katov, Lyuboslav / Mayer, Benjamin / Rottbauer, Wolfgang / Bothner, Carlo / Weinmann, Karolina

    Journal of clinical medicine

    2024  Volume 13, Issue 4

    Abstract: Background/ ... ...

    Abstract Background/Objectives
    Language English
    Publishing date 2024-02-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13040963
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  4. Article ; Online: Deferral of non-emergency cardiac interventions is associated with increased emergency hospitalizations up to 24 months post-procedure.

    Andreß, Stefanie / Felbel, Dominik / Buckert, Dominik / Rottbauer, Wolfgang / Imhof, Armin / Stephan, Tilman

    Clinical research in cardiology : official journal of the German Cardiac Society

    2024  

    Abstract: Background: Patients, whose non-emergency cardiac procedure was postponed during the COVID-19 pandemic, have shown signs of disease progression in the short term. Data on the long-term effects are currently lacking.: Aim: To assess outcomes through 3  ...

    Abstract Background: Patients, whose non-emergency cardiac procedure was postponed during the COVID-19 pandemic, have shown signs of disease progression in the short term. Data on the long-term effects are currently lacking.
    Aim: To assess outcomes through 3 years following deferral.
    Methods: This retrospective, single-center analysis includes consecutive patients whose non-emergency cardiovascular intervention was postponed during the first COVID-19-related lockdown (March 19 to April 30, 2020). Outcomes over 36 months post-procedure were analyzed and compared to a seasonal control group undergoing non-emergency intervention in 2019 as scheduled (n = 214). The primary endpoint was a composite of emergency cardiovascular hospitalization and death. Additionally, NT-proBNP levels were analyzed.
    Results: The combined endpoint occurred in 60 of 178 patients (33.7%) whose non-emergency transcatheter heart valve intervention, rhythmological procedure, or left heart catheterization was postponed. Primary endpoint events did not occur more frequently in the study group during the 36-month follow-up (p = 0.402), but within the first 24 months post-procedure (HR 1.77, 95% CI 1.20-2.60, p = 0.003). Deferred patients affected by an event in the postprocedural 24 months had significantly higher NT-proBNP levels at the time of intervention (p < 0.001) (AUC 0.768, p = 0.003, optimum cut-off 808.5 pg/ml, sensitivity 84.2%, specificity 65.8%) and thereafter (p < 0.001).
    Conclusion: Deferral of non-emergency cardiovascular interventions is associated with poor outcomes up to 24 months post-procedure. Adverse effects affect patients who develop signs of acute heart failure, as indicated by NT-proBNP, prior to treatment. These findings could help improve resource allocation in times of limited capacity.
    Language English
    Publishing date 2024-03-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2213295-8
    ISSN 1861-0692 ; 1861-0684
    ISSN (online) 1861-0692
    ISSN 1861-0684
    DOI 10.1007/s00392-024-02380-y
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  5. Article: Pulmonary Vein Isolation with a Novel Size-Adjustable Cryo-Balloon Catheter: A Tailored Ablation Protocol.

    Teumer, Yannick / Hilgarth, Franziska / Katov, Lyuboslav / Melnic, Rima / Rottbauer, Wolfgang / Bothner, Carlo / Weinmann, Karolina

    Journal of clinical medicine

    2024  Volume 13, Issue 8

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-04-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13082262
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  6. Article ; Online: Acute Chest Pain Following Parenteral Infusion.

    Rattka, Manuel / Rottbauer, Wolfgang / Markovic, Sinisa

    Deutsches Arzteblatt international

    2022  Volume 118, Issue 49, Page(s) 841

    MeSH term(s) Chest Pain/diagnosis ; Chest Pain/etiology ; Humans ; Infusions, Intravenous ; Infusions, Parenteral
    Language English
    Publishing date 2022-03-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2406159-1
    ISSN 1866-0452 ; 1866-0452
    ISSN (online) 1866-0452
    ISSN 1866-0452
    DOI 10.3238/arztebl.m2021.0094
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  7. Article ; Online: 3D localization from 2D X-ray projection.

    Bertsche, Dagmar / Rasche, Volker / Rottbauer, Wolfgang / Vernikouskaya, Ina

    International journal of computer assisted radiology and surgery

    2022  Volume 17, Issue 9, Page(s) 1553–1558

    Abstract: Purpose: Most cardiology procedures are guided using X-ray (XR) fluoroscopy. However, the projective nature of the XR fluoroscopy does not allow for true depth perception as required for safe and efficient intervention guidance in structural heart ... ...

    Abstract Purpose: Most cardiology procedures are guided using X-ray (XR) fluoroscopy. However, the projective nature of the XR fluoroscopy does not allow for true depth perception as required for safe and efficient intervention guidance in structural heart diseases. For improving guidance, different methods have been proposed often being radiation-intensive, time-consuming, or expensive. We propose a simple 3D localization method based on a single monoplane XR projection using a co-registered centerline model.
    Methods: The method is based on 3D anatomic surface models and corresponding centerlines generated from preprocedural imaging. After initial co-registration, 2D working points identified in monoplane XR projections are localized in 3D by minimizing the angle between the projection lines of the centerline points and the working points. The accuracy and reliability of the located 3D positions were assessed in 3D using phantom data and in patient data projected to 2D obtained during placement of embolic protection system in interventional procedures.
    Results: With the proposed methods, 2D working points identified in monoplane XR could be successfully located in the 3D phantom and in the patient-specific 3D anatomy. Accuracy in the phantom (3D) resulted in 1.6 mm (± 0.8 mm) on average, and 2.7 mm (± 1.3 mm) on average in the patient data (2D).
    Conclusion: The use of co-registered centerline models allows reliable and accurate 3D localization of devices from a single monoplane XR projection during placement of the embolic protection system in TAVR. The extension to different vascular interventions and combination with automatic methods for device detection and registration might be promising.
    MeSH term(s) Algorithms ; Fluoroscopy/methods ; Humans ; Imaging, Three-Dimensional/methods ; Phantoms, Imaging ; Reproducibility of Results ; X-Rays
    Language English
    Publishing date 2022-07-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2365628-1
    ISSN 1861-6429 ; 1861-6410
    ISSN (online) 1861-6429
    ISSN 1861-6410
    DOI 10.1007/s11548-022-02709-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6615: Show issues Location:
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  8. Article ; Online: Deep learning-based framework for motion-compensated image fusion in catheterization procedures.

    Vernikouskaya, Ina / Bertsche, Dagmar / Rottbauer, Wolfgang / Rasche, Volker

    Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society

    2022  Volume 98, Page(s) 102069

    Abstract: Objective: Augmenting X-ray (XR) fluoroscopy with 3D anatomic overlays is an essential technique to improve the guidance of the catheterization procedures. Unfortunately, cardiac and respiratory motion compromises the augmented fluoroscopy. Motion ... ...

    Abstract Objective: Augmenting X-ray (XR) fluoroscopy with 3D anatomic overlays is an essential technique to improve the guidance of the catheterization procedures. Unfortunately, cardiac and respiratory motion compromises the augmented fluoroscopy. Motion compensation methods can be applied to update the overlay of a static model with regard to respiratory and cardiac motion. We investigate the feasibility of motion detection between two fluoroscopic frames by applying a convolutional neural network (CNN). Its integration in the existing open-source software framework 3D-XGuide is demonstrated, such extending its functionality to automatic motion detection and compensation.
    Methods: The CNN is trained on reference data generated from tracking of the rapid pacing catheter tip by applying template matching with normalized cross-correlation (CC). The developed CNN motion compensation model is packaged in a standalone web service, allowing for independent use via a REST API. For testing and demonstration purposes, we have extended the functionality of 3D-XGuide navigation framework by an additional motion compensation module, which uses the displacement predictions of the standalone CNN model service for motion compensation of the static 3D model overlay. We provide the source code on GitHub under BSD license.
    Results: The performance of the CNN motion compensation model was evaluated on a total of 1690 fluoroscopic image pairs from ten clinical datasets. The CNN model-based motion compensation method clearly overperformed the tracking of the rapid pacing catheter tip with CC with prediction frame rates suitable for live application in the clinical setting.
    Conclusion: A novel CNN model-based method for automatic motion compensation during fusion of 3D anatomic models with XR fluoroscopy is introduced and its integration with a real software application demonstrated. Automatic motion extraction from 2D XR images using a CNN model appears as a substantial improvement for reliable augmentation during catheter interventions.
    MeSH term(s) Catheterization ; Deep Learning ; Fluoroscopy/methods ; Motion ; Neural Networks, Computer
    Language English
    Publishing date 2022-05-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639451-6
    ISSN 1879-0771 ; 0895-6111
    ISSN (online) 1879-0771
    ISSN 0895-6111
    DOI 10.1016/j.compmedimag.2022.102069
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  9. Book ; Thesis: Nichtinvasive Quantifizierung von Aorten- und Mitralklappeninsuffizienzen

    Rottbauer, Wolfgang

    Vergleich zwischen dynamischer Magnetresonanztomographie und Farbdopplerechokardiographie

    1994  

    Author's details vorgelegt von Wolfgang Rottbauer
    Language German
    Size II, 60 S. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Würzburg, Univ., Diss., 1995
    HBZ-ID HT006765424
    Database Catalogue ZB MED Medicine, Health

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  10. Article ; Online: Valve unit instead of intensive or intermediate care unit admission following transcatheter edge-to-edge mitral valve repair is safe and reduces postprocedural complications.

    Gröger, Matthias / Felbel, Dominik / Paukovitsch, Michael / Schneider, Leonhard Moritz / Markovic, Sinisa / Rottbauer, Wolfgang / Keßler, Mirjam

    Clinical research in cardiology : official journal of the German Cardiac Society

    2024  

    Abstract: Background: Transcatheter edge-to-edge mitral valve repair (M-TEER) is often performed in general anesthesia, and postprocedural monitoring is usually warranted on an intensive or intermediate care unit (ICU/IMC). We evaluated the implications of a ... ...

    Abstract Background: Transcatheter edge-to-edge mitral valve repair (M-TEER) is often performed in general anesthesia, and postprocedural monitoring is usually warranted on an intensive or intermediate care unit (ICU/IMC). We evaluated the implications of a dedicated valve unit (VU) instead of an ICU/IMC for monitoring after M-TEER.
    Methods and results: In total, 624 patients were retrospectively analyzed. A total of 312 patients were primarily transferred to either ICU or IMC following M-TEER, and 312 patients were scheduled for the VU in the absence of indications for ICU/IMC treatment. Hospital stay was significantly shorter in VU patients (median 6.0 days (interquartile range (IQR) 5.0 - 8.0) vs. 7.0 days (IQR 6.0 - 10.0), p < 0.001) and their risk for infections (2.9 vs. 7.7%, p = 0.008) and delirium (0.6 vs. 2.6%, p = 0.056) was substantially lower compared to ICU/IMC patients. In-hospital mortality was similar in both groups (0.6% vs. 1.3%, p = 0.41). Fifty patients (16.0%) in the VU group had to cross over to unplanned ICU/IMC admission. The most frequent indication was prolonged need for catecholamines (52.0%). Patients with ICU/IMC crossover had more advanced stages of heart failure (LV-EF < 30% in 36.0 vs. 16.0%, p = 0.001; severe concomitant tricuspid regurgitation in 48.0 vs. 27.8%, p = 0.005) and an LV-EF < 30% was independently associated with unplanned ICU/IMC admission.
    Conclusions: Following M-TEER postprocedural monitoring on a VU instead of an ICU/IMC is safe, reduces complications, and spares ICU capacities. Patients with advanced heart failure have a higher risk for unplanned ICU/IMC treatment after M-TEER.
    Language English
    Publishing date 2024-02-14
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2213295-8
    ISSN 1861-0692 ; 1861-0684
    ISSN (online) 1861-0692
    ISSN 1861-0684
    DOI 10.1007/s00392-024-02384-8
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