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  1. Article ; Online: Effects of cryopreservation on antiviral responses of primary airway epithelial cells.

    Taka, Styliani / Nikopoulou, Chrysa / Polyzos, Alexandros / Megremis, Spyridon / Skevaki, Chrysanthi L / Roumpedaki, Eirini / Trochoutsou, Aikaterini / Thanos, Dimitris / Papadopoulos, Nikolaos G

    Allergy

    2020  Volume 75, Issue 6, Page(s) 1486–1489

    MeSH term(s) Antiviral Agents ; Cells, Cultured ; Cryopreservation ; Epithelial Cells ; Respiratory System ; Rhinovirus
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2020-02-08
    Publishing country Denmark
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 391933-x
    ISSN 1398-9995 ; 0105-4538
    ISSN (online) 1398-9995
    ISSN 0105-4538
    DOI 10.1111/all.14163
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.150: Show issues Location:
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    Zs.MO 125: Show issues

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  2. Article ; Online: Infantile growth velocity and later asthma/wheeze: GENESIS and the Healthy Growth Study.

    Guibas, George V / Manios, Yannis / Moschonis, George / Xepapadaki, Paraskevi / Roumpedaki, Eirini / Lambrinou, Christina-Paulina / Papadopoulos, Nikolaos G

    The European respiratory journal

    2014  Volume 43, Issue 6, Page(s) 1790–1793

    MeSH term(s) Anthropometry ; Asthma/complications ; Child ; Child Development ; Child Nutrition Sciences ; Child, Preschool ; Cohort Studies ; Cross-Sectional Studies ; Greece ; Humans ; Infant ; Infant, Newborn ; Respiratory Sounds/diagnosis ; Social Class
    Language English
    Publishing date 2014-06
    Publishing country England
    Document type Letter
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/09031936.00129513
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2322: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 292: Show issues

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  3. Article ; Online: A child with anaphylactic reaction by egg remedy applied to burn.

    Roumpedaki, Eirini / Douladiris, Nikolaos / Papanaki, Anna / Stamogiannou, Lela / Maggina, Paraskevi / Manoussakis, Emmanuel / Vallianatou, Gerasimina / Papadopoulos, Nikolaos G / Xepapadaki, Paraskevi

    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

    2014  Volume 25, Issue 6, Page(s) 606–608

    MeSH term(s) Administration, Cutaneous ; Anaphylaxis/diagnosis ; Anaphylaxis/etiology ; Anaphylaxis/therapy ; Burns, Chemical/complications ; Burns, Chemical/diagnosis ; Burns, Chemical/therapy ; Egg Hypersensitivity/complications ; Egg Hypersensitivity/diagnosis ; Egg Hypersensitivity/therapy ; Eggs/utilization ; Epinephrine/administration & dosage ; Humans ; Immunoglobulin E/blood ; Infant ; Male ; Medicine, Traditional/methods ; Resuscitation ; Skin/immunology ; Skin/metabolism ; Skin/pathology ; Skin Tests ; Tryptases/blood
    Chemical Substances Immunoglobulin E (37341-29-0) ; Tryptases (EC 3.4.21.59) ; Epinephrine (YKH834O4BH)
    Language English
    Publishing date 2014-10
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 1057059-7
    ISSN 1399-3038 ; 0905-6157 ; 0906-5784
    ISSN (online) 1399-3038
    ISSN 0905-6157 ; 0906-5784
    DOI 10.1111/pai.12240
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    Zs.A 3096: Show issues Location:
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  4. Article ; Online: Contribution of repeated infections in asthma persistence from preschool to school age: Design and characteristics of the PreDicta cohort.

    Xepapadaki, Paraskevi / Bachert, Claus / Finotto, Susetta / Jartti, Tuomas / Konstantinou, George N / Kiefer, Alexander / Kowalski, Marek / Lewandowska-Polak, Anna / Lukkarinen, Heikki / Roumpedaki, Eirini / Sobanska, Anna / Sintobin, Ina / Vuorinen, Tytti / Zhang, Nan / Zimmermann, Theodor / Papadopoulos, Nikolaos G

    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

    2018  Volume 29, Issue 4, Page(s) 383–393

    Abstract: Background: The PreDicta cohort was designed to prospectively evaluate wheeze/asthma persistence in preschoolers in association with viral/microbial exposures and immunological responses. We present the cohort design and demographic/disease ... ...

    Abstract Background: The PreDicta cohort was designed to prospectively evaluate wheeze/asthma persistence in preschoolers in association with viral/microbial exposures and immunological responses. We present the cohort design and demographic/disease characteristics and evaluate unsupervised and predefined phenotypic subgroups at inclusion.
    Methods: PreDicta is a 2-year prospective study conducted in five European regions, including children 4-6 years with a diagnosis of asthma as cases and healthy age-matched controls. At baseline, detailed information on demographics, asthma and allergy-related disease activity, exposures, and lifestyle were recorded. Lung function, airway inflammation, and immune responses were also assessed. Power analysis confirmed that the cohort is adequate to answer the initial hypothesis.
    Results: A total of 167 asthmatic children (102 males) and 66 healthy controls (30 males) were included. Groups were homogeneous in respect to most baseline characteristics, with the exception of male gender in cases (61%) and exposure to tobacco smoke. Comorbidities and number and duration of infections were significantly higher in asthmatics than controls. 55.7% of asthmatic children had at least one positive skin prick test to aeroallergens (controls: 33.3%, P = .002). Spirometric and exhaled nitric oxide values were within normal limits; only baseline FEV
    Conclusions: The PreDicta cohort presented no differences in non-asthma related measures; however, it is well balanced regarding key phenotypic characteristics representative of "preschool asthma".
    MeSH term(s) Asthma/immunology ; Asthma/microbiology ; Case-Control Studies ; Child ; Child, Preschool ; Disease Progression ; Female ; Follow-Up Studies ; Humans ; Infection/complications ; Infection/immunology ; Linear Models ; Male ; Prospective Studies ; Recurrence ; Research Design ; Respiratory Sounds/immunology ; Risk Factors ; Virus Diseases/complications ; Virus Diseases/immunology
    Language English
    Publishing date 2018-04-10
    Publishing country England
    Document type Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 1057059-7
    ISSN 1399-3038 ; 0905-6157 ; 0906-5784
    ISSN (online) 1399-3038
    ISSN 0905-6157 ; 0906-5784
    DOI 10.1111/pai.12881
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3096: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Anaphylaxis in children and adolescents: The European Anaphylaxis Registry.

    Grabenhenrich, Linus B / Dölle, Sabine / Moneret-Vautrin, Anne / Köhli, Alice / Lange, Lars / Spindler, Thomas / Ruëff, Franziska / Nemat, Katja / Maris, Ioana / Roumpedaki, Eirini / Scherer, Kathrin / Ott, Hagen / Reese, Thomas / Mustakov, Tihomir / Lang, Roland / Fernandez-Rivas, Montserrat / Kowalski, Marek L / Bilò, Maria B / Hourihane, Jonathan O'B /
    Papadopoulos, Nikolaos G / Beyer, Kirsten / Muraro, Antonella / Worm, Margitta

    The Journal of allergy and clinical immunology

    2016  Volume 137, Issue 4, Page(s) 1128–1137.e1

    Abstract: Background: Anaphylaxis in children and adolescents is a potentially life-threatening condition. Its heterogeneous clinical presentation and sudden occurrence in virtually any setting without warning have impeded a comprehensive description.: ... ...

    Abstract Background: Anaphylaxis in children and adolescents is a potentially life-threatening condition. Its heterogeneous clinical presentation and sudden occurrence in virtually any setting without warning have impeded a comprehensive description.
    Objective: We sought to characterize severe allergic reactions in terms of elicitors, symptoms, emergency treatment, and long-term management in European children and adolescents.
    Methods: The European Anaphylaxis Registry recorded details of anaphylaxis after referral for in-depth diagnosis and counseling to 1 of 90 tertiary allergy centers in 10 European countries, aiming to oversample the most severe reactions. Data were retrieved from medical records by using a multilanguage online form.
    Results: Between July 2007 and March 2015, anaphylaxis was identified in 1970 patients younger than 18 years. Most incidents occurred in private homes (46%) and outdoors (19%). One third of the patients had experienced anaphylaxis previously. Food items were the most frequent trigger (66%), followed by insect venom (19%). Cow's milk and hen's egg were prevalent elicitors in the first 2 years, hazelnut and cashew in preschool-aged children, and peanut at all ages. There was a continuous shift from food- to insect venom- and drug-induced anaphylaxis up to age 10 years, and there were few changes thereafter. Vomiting and cough were prevalent symptoms in the first decade of life, and subjective symptoms (nausea, throat tightness, and dizziness) were prevalent later in life. Thirty percent of cases were lay treated, of which 10% were treated with an epinephrine autoinjector. The fraction of intramuscular epinephrine in professional emergency treatment increased from 12% in 2011 to 25% in 2014. Twenty-six (1.3%) patients were either admitted to the intensive care unit or had grade IV/fatal reactions.
    Conclusions: The European Anaphylaxis Registry confirmed food as the major elicitor of anaphylaxis in children, specifically hen's egg, cow's milk, and nuts. Reactions to insect venom were seen more in young adulthood. Intensive care unit admissions and grade IV/fatal reactions were rare. The registry will serve as a systematic foundation for a continuous description of this multiform condition.
    MeSH term(s) Adolescent ; Anaphylaxis/diagnosis ; Anaphylaxis/epidemiology ; Anaphylaxis/etiology ; Anaphylaxis/therapy ; Child ; Child, Preschool ; Emergency Treatment ; Europe/epidemiology ; Female ; Health Care Surveys ; Health Surveys ; Humans ; Infant ; Infant, Newborn ; Male ; Registries ; Retrospective Studies
    Language English
    Publishing date 2016-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2015.11.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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