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  1. Book ; Collection: Oxidative stress and toxicity in reproductive biology and medicine

    Kesari, Kavindra Kumar / Roychoudhury, Shubhadeep

    a comprehensive update on male infertility

    (Advances in experimental medicine and biology)

    2022  

    Author's details Kavindra Kumar Kesari, Shubhadeep Roychoudhury editors
    Series title Advances in experimental medicine and biology
    Keywords Infertility, Male ; Oxidative stress
    Subject code 616.692
    Language English
    Dates of publication 2022-9999
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Collection (display volumes)
    HBZ-ID HT021397288
    Database Catalogue ZB MED Medicine, Health

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  2. Book: Oxidative stress and toxicity in reproductive biology and medicine / Volume 1

    Kesari, Kavindra Kumar / Roychoudhury, Shubhadeep

    a comprehensive update on male infertility

    (Advances in experimental medicine and biology ; 1358)

    2022  

    Author's details Kavindra Kumar Kesari, Shubhadeep Roychoudhury editors
    Series title Advances in experimental medicine and biology ; 1358
    Oxidative stress and toxicity in reproductive biology and medicine
    Collection Oxidative stress and toxicity in reproductive biology and medicine
    Language English
    Size xii, 379 Seiten, Diagramme
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT021409718
    ISBN 978-3-030-89339-2 ; 9783030893408 ; 3-030-89339-1 ; 3030893405
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 3192 -1358- not available for loan Lesesaal EG

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  3. Book: Oxidative stress and toxicity in reproductive biology and medicine / Volume 2

    Kesari, Kavindra Kumar / Roychoudhury, Shubhadeep

    a comprehensive update on male infertility

    (Advances in experimental medicine and biology ; 1391)

    2022  

    Author's details Kavindra Kumar Kesari, Shubhadeep Roychoudhury editors
    Series title Advances in experimental medicine and biology ; 1391
    Oxidative stress and toxicity in reproductive biology and medicine
    Collection Oxidative stress and toxicity in reproductive biology and medicine
    Language English
    Size xv, 342 Seiten, Illustrationen
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT021691540
    ISBN 978-3-031-12965-0 ; 9783031129667 ; 3-031-12965-2 ; 3031129660
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 3192 -1391- not available for loan Lesesaal EG

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  4. Article: Pathological Roles of Reactive Oxygen Species in Male Reproduction.

    Chakraborty, Saptaparna / Roychoudhury, Shubhadeep

    Advances in experimental medicine and biology

    2022  Volume 1358, Page(s) 41–62

    Abstract: Reactive oxygen species (ROS) are free radicals that have at least one unpaired electron and play specific roles in the human body. An imbalance of ROS and antioxidant levels gives rise to a condition called oxidative stress. High levels of ROS in the ... ...

    Abstract Reactive oxygen species (ROS) are free radicals that have at least one unpaired electron and play specific roles in the human body. An imbalance of ROS and antioxidant levels gives rise to a condition called oxidative stress. High levels of ROS in the male reproductive tract can interfere with its normal functioning and can even pose as toxic to the sperm, inhibiting sperm functioning (including motility) and metabolism. Oxidative stress resulting from ROS and lipid peroxidation is one of the major causes of male infertility including infertility in varicocele patients. These may cause DNA and peroxidative damage and apoptosis. Production of ROS in excess also leads to erectile dysfunction (ED). In recent years, studies have also linked oxidative stress with the development, progress, and therapy response of prostate cancer patients. The present study summarizes the pathological roles of ROS in male reproductive problems such as infertility, ED, and prostate cancer and also provide an insight into the probable mechanism through which ROS exert their pathological impact.
    MeSH term(s) Erectile Dysfunction ; Humans ; Infertility, Male/metabolism ; Male ; Oxidative Stress/physiology ; Prostatic Neoplasms/complications ; Reactive Oxygen Species/metabolism ; Reproduction
    Chemical Substances Reactive Oxygen Species
    Language English
    Publishing date 2022-05-31
    Publishing country United States
    Document type Journal Article
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-3-030-89340-8_3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Reactive Oxygen Species in the Reproductive System: Sources and Physiological Roles.

    Das, Anandan / Roychoudhury, Shubhadeep

    Advances in experimental medicine and biology

    2022  Volume 1358, Page(s) 9–40

    Abstract: Reactive oxygen species (ROS) are oxygen-containing molecules which are reactive in nature and are capable of independent existence in the body. ROS comprise mostly of free radicals that contain at least one unpaired electron. Endogenous sources are the ... ...

    Abstract Reactive oxygen species (ROS) are oxygen-containing molecules which are reactive in nature and are capable of independent existence in the body. ROS comprise mostly of free radicals that contain at least one unpaired electron. Endogenous sources are the foremost birthplaces of ROS, which include mitochondrial electron transport chain, endoplasmic reticulum and peroxisome. Conversely, numerous enzymatic pathways such as xanthine oxidase and cyclooxygenase systems are among the prominent generators of cellular ROS. Major sources of ROS in the female reproductive tract include Graafian follicles, follicular fluid, fallopian tube, peritoneal cavity and endometrium. On the contrary, leukocytes, immature spermatozoa and varicocele are the key originators of ROS in the male reproductive system. For the sake of maintaining a proper oxidative balance, cells have evolved a variety of antioxidative molecules. From the physiological perspective, ROS and antioxidants are actively involved in the regulation of myriad female reproductive processes, such as cyclic luteal and endometrial changes, follicular development, ovulation, fertilization, embryonic implantation, maintenance of pregnancy and parturition. Similarly, physiological amounts of ROS are crucial in the accomplishment of various male reproductive functions as well, which include spermatozoa maturation, capacitation, hyperactivation and acrosome reaction. This chapter highlights the birthplaces of ROS in the female and male reproductive tract along with mechanisms of their production. This chapter will also put forward specific physiological roles of these reactive molecules in upholding the structural integrity and functionality of both the reproductive systems.
    MeSH term(s) Antioxidants/metabolism ; Female ; Humans ; Infertility, Male/metabolism ; Male ; Oxidative Stress/physiology ; Pregnancy ; Reactive Oxygen Species/metabolism ; Spermatozoa/physiology
    Chemical Substances Antioxidants ; Reactive Oxygen Species
    Language English
    Publishing date 2022-05-31
    Publishing country United States
    Document type Journal Article
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-3-030-89340-8_2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Editorial: DNA damage and repair in reproductive and embryo cells.

    Rocco, Lucia / Mottola, Filomena / Roychoudhury, Shubhadeep

    Frontiers in cell and developmental biology

    2023  Volume 11, Page(s) 1274341

    Language English
    Publishing date 2023-08-29
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2023.1274341
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: 'Intracytoplasmic sperm injection (ICSI) paradox' and 'andrological ignorance': AI in the era of fourth industrial revolution to navigate the blind spots.

    Sengupta, Pallav / Dutta, Sulagna / Jegasothy, Ravindran / Slama, Petr / Cho, Chak-Lam / Roychoudhury, Shubhadeep

    Reproductive biology and endocrinology : RB&E

    2024  Volume 22, Issue 1, Page(s) 22

    Abstract: The quandary known as the Intracytoplasmic Sperm Injection (ICSI) paradox is found at the juncture of Assisted Reproductive Technology (ART) and 'andrological ignorance' - a term coined to denote the undervalued treatment and comprehension of male ... ...

    Abstract The quandary known as the Intracytoplasmic Sperm Injection (ICSI) paradox is found at the juncture of Assisted Reproductive Technology (ART) and 'andrological ignorance' - a term coined to denote the undervalued treatment and comprehension of male infertility. The prevalent use of ICSI as a solution for severe male infertility, despite its potential to propagate genetically defective sperm, consequently posing a threat to progeny health, illuminates this paradox. We posit that the meteoric rise in Industrial Revolution 4.0 (IR 4.0) and Artificial Intelligence (AI) technologies holds the potential for a transformative shift in addressing male infertility, specifically by mitigating the limitations engendered by 'andrological ignorance.' We advocate for the urgent need to transcend andrological ignorance, envisaging AI as a cornerstone in the precise diagnosis and treatment of the root causes of male infertility. This approach also incorporates the identification of potential genetic defects in descendants, the establishment of knowledge platforms dedicated to male reproductive health, and the optimization of therapeutic outcomes. Our hypothesis suggests that the assimilation of AI could streamline ICSI implementation, leading to an overall enhancement in the realm of male fertility treatments. However, it is essential to conduct further investigations to substantiate the efficacy of AI applications in a clinical setting. This article emphasizes the significance of harnessing AI technologies to optimize patient outcomes in the fast-paced domain of reproductive medicine, thereby fostering the well-being of upcoming generations.
    MeSH term(s) Male ; Humans ; Sperm Injections, Intracytoplasmic ; Artificial Intelligence ; Semen ; Infertility, Male/diagnosis ; Infertility, Male/genetics ; Infertility, Male/therapy ; Reproductive Techniques, Assisted
    Language English
    Publishing date 2024-02-13
    Publishing country England
    Document type Letter
    ZDB-ID 2119215-7
    ISSN 1477-7827 ; 1477-7827
    ISSN (online) 1477-7827
    ISSN 1477-7827
    DOI 10.1186/s12958-024-01193-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Environmental and occupational exposure of metals and female reproductive health

    Gorain, Bapi / Choudhury, Hira / Roychoudhury, Shubhadeep / Sengupta, Pallav

    Environ Sci Pollut Res. 2022 Sept., v. 29, no. 41 p.62067-62092

    2022  

    Abstract: Untainted environment promotes health, but the last few decades experienced steep upsurge in environmental contaminants posing detrimental physiological impact. The responsible factors mainly include the exponential growth of human population, havoc rise ...

    Abstract Untainted environment promotes health, but the last few decades experienced steep upsurge in environmental contaminants posing detrimental physiological impact. The responsible factors mainly include the exponential growth of human population, havoc rise in industrialization, poorly planned urbanization, and slapdash environment management. Environmental degradation can increase the likelihood of human exposure to heavy metals, resulting in health consequences such as reproductive problems. As a result, research into metal-induced causes of reproductive impairment at the genetic, epigenetic, and biochemical levels must be strengthened further. These metals impact upon the female reproduction at all strata of its regulation and functions, be it development, maturation, or endocrine functions, and are linked to an increase in the causes of infertility in women. Chronic exposures to the heavy metals may lead to breast cancer, endometriosis, endometrial cancer, menstrual disorders, and spontaneous abortions, as well as pre-term deliveries, stillbirths. For example, endometriosis, endometrial cancer, and spontaneous abortions are all caused by the metalloestrogen cadmium (Cd); lead (Pb) levels over a certain threshold can cause spontaneous abortion and have a teratogenic impact; toxic amounts of mercury (Hg) have an influence on the menstrual cycle, which can lead to infertility. Impact of environmental exposure to heavy metals on female fertility is therefore a well-known fact. Thus, the underlying mechanisms must be explained and periodically updated, given the growing evidence on the influence of increasing environmental heavy metal load on female fertility. The purpose of this review is to give a concise overview of how heavy metal affects female reproductive health.
    Keywords abortion (animals) ; breast neoplasms ; cadmium ; endometriosis ; epigenetics ; female fertility ; females ; heavy metals ; human population ; humans ; industrialization ; lead ; menstrual cycle ; mercury ; occupational exposure ; pollution ; teratogenicity ; urbanization ; uterine neoplasms
    Language English
    Dates of publication 2022-09
    Size p. 62067-62092.
    Publishing place Springer Berlin Heidelberg
    Document type Article ; Online
    Note Review
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-021-16581-9
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 5915: Show issues

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  9. Article: Revolutionizing semen analysis: introducing Mojo AISA, the next-gen artificial intelligence microscopy.

    Sengupta, Pallav / Dutta, Sulagna / Roychoudhury, Shubhadeep / Vizzarri, Francesco / Slama, Petr

    Frontiers in cell and developmental biology

    2023  Volume 11, Page(s) 1203708

    Language English
    Publishing date 2023-06-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2023.1203708
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Sea buckthorn, its bioactive constituents, and mechanism of action: potential application in female reproduction.

    Mihal, Michal / Roychoudhury, Shubhadeep / Sirotkin, Alexander V / Kolesarova, Adriana

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1244300

    Abstract: Sea buckthorn ( ...

    Abstract Sea buckthorn (
    MeSH term(s) Animals ; Female ; Humans ; Hippophae ; Quercetin ; Prospective Studies ; Vascular Endothelial Growth Factor A ; Flavonoids ; Carotenoids ; Ovarian Neoplasms ; Hormones
    Chemical Substances Quercetin (9IKM0I5T1E) ; Vascular Endothelial Growth Factor A ; Flavonoids ; Carotenoids (36-88-4) ; Hormones
    Language English
    Publishing date 2023-11-07
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1244300
    Database MEDical Literature Analysis and Retrieval System OnLINE

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