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  1. AU="Rubino, Carlotta"
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  1. Article: An integrative morpho-molecular approach in malignant ectomesenchymoma diagnosis: report of a new paediatric case and a review of the literature.

    Pellegrino, Francesco / Tirtei, Elisa / Divincenzo, Federico / Campello, Anna / Rubino, Carlotta / Augustoni, Elisabetta / Linari, Alessandra / Asaftei, Sebastian Dorin / Fagioli, Franca

    Frontiers in oncology

    2024  Volume 14, Page(s) 1320541

    Abstract: Introduction: Malignant ectomesenchymoma (MEM) is a soft tissue tumour, consisting of both malignant neuroectodermal elements and one or more mesenchymal elements.: Case presentation and review of the literature: Here we describe the case of a 6- ... ...

    Abstract Introduction: Malignant ectomesenchymoma (MEM) is a soft tissue tumour, consisting of both malignant neuroectodermal elements and one or more mesenchymal elements.
    Case presentation and review of the literature: Here we describe the case of a 6-months-old male, previously treated in another hospital for abdominal rhabdomyosarcoma (RMS). Histological re-examination demonstrated that the tumour had mesenchymal and neuroectodermal elements components, with a new diagnosis of abdominal-pelvic MEM. A Next-Generation Sequencing (NGS) analysis was performed on a surgical tumour specimen and revealed the presence of a somatic mutation, already reported in MEM cases. We carried out a review of the literature and we found 33 new cases of MEM since the last review. We reported the clinic-pathologic features of new cases of MEM, highlighting the role of molecular studies in supporting the diagnosis of this ambiguous tumours.
    Conclusion: We promote the importance of a diagnosis based on an integrative morpho-molecular approach, that routinely include molecular analysis and the use of bioinformatic mutation detection tools, to support diagnostic and therapeutical queries and to highlight tumour biology and behaviour.
    Language English
    Publishing date 2024-03-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2024.1320541
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Risk of Symptomatic Infection after Non-Primary Congenital Cytomegalovirus Infection

    Coscia, Alessandra / Leone, Agata / Rubino, Carlotta / Galitska, Ganna / Biolatti, Matteo / Bertino, Enrico / Peila, Chiara / Cresi, Francesco

    Microorganisms. 2020 May 25, v. 8, no. 5

    2020  

    Abstract: Cytomegalovirus (CMV) is the leading cause of congenital infection. Its occurrence is phenotypically heterogeneous. The type of maternal infection, primary or non-primary, is an important factor related to the symptomatic disease, the primary infection ... ...

    Abstract Cytomegalovirus (CMV) is the leading cause of congenital infection. Its occurrence is phenotypically heterogeneous. The type of maternal infection, primary or non-primary, is an important factor related to the symptomatic disease, the primary infection was long considered the only cause of severe neonatal disease. We aimed to analyze the association of primary and non-primary infection with pathological outcomes in infants and with long-term sequelae at follow-up. This was a monocentric retrospective observational study on a population of 91 infants diagnosed with a CMV infection at the Neonatal Care Unit of Neonatology at the Sant’Anna Hospital of Turin during the period of June 2005 to December 2018. Infants underwent clinical, laboratory, and neuroradiological evaluations at birth. Subsequently, the patients were monitored in an auxological, neurodevelopment, and audiological follow-up. Regarding primary vs. non-primary infection, we found a higher percentage of incidence of symptomatic and neurological localized infection, as well as long-term sequelae in the latter. However, no significant difference between the two populations was found. We underline the possibility of re-infection in previously immunized mothers (non-primary infection) with unfavorable neonatal and long-term outcomes.
    Keywords Cytomegalovirus ; Cytomegalovirus infections ; complications (disease) ; hospitals ; neurodevelopment ; observational studies ; risk
    Language English
    Dates of publication 2020-0525
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms8050786
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: Fresh autologous stromal tissue fraction for the treatment of knee osteoarthritis related pain and disability.

    Santoprete, Stefano / Marchetti, Federica / Rubino, Carlotta / Bedini, Maria Grazie / Nasto, Luigi Aurelio / Cipolloni, Valerio / Pola, Enrico

    Orthopedic reviews

    2021  Volume 13, Issue 1, Page(s) 9161

    Abstract: Knee osteoarthritis (KOA) is a very common condition with multifactorial etiology leading to severe pain and disability in the adult population. Although KOA is considered a non-inflammatory arthritis, upregulation of inflammatory and catabolic pathways ... ...

    Abstract Knee osteoarthritis (KOA) is a very common condition with multifactorial etiology leading to severe pain and disability in the adult population. Although KOA is considered a non-inflammatory arthritis, upregulation of inflammatory and catabolic pathways with increased production of proinflammatory cytokines leading to cartilage degradation and extracellular matrix degeneration has been reported. Intra-articular injection of fresh fat derived stromal vascular fraction (SVF) fraction has been proposed as a valid and alternative treatment for symptomatic KOA that guarantees mechanical support through viscosupplementation, anti-inflammatory, and anabolic action. We retrospectively reviewed a case series of 84 consecutive adult patients with KOA who underwent intra-articular injection of fresh fat derived SVF. Significant improvement in pain levels (NRS score decrease 3.5±1.1, p<0.001), WOMAC pain (-7.02±3.45 score change, p<0.001), WOMAC stiffness (-1.97±1.02, p<0.001), and ROM improvement (+17.13±5.22°, p<0.001). The only complication noted was knee joint swelling lasting for less than 7 days after the injection in 7% of the patients.
    Language English
    Publishing date 2021-03-31
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2508171-8
    ISSN 2035-8164 ; 2035-8237
    ISSN (online) 2035-8164
    ISSN 2035-8237
    DOI 10.4081/or.2021.9161
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Risk of Symptomatic Infection after Non-Primary Congenital Cytomegalovirus Infection.

    Coscia, Alessandra / Leone, Agata / Rubino, Carlotta / Galitska, Ganna / Biolatti, Matteo / Bertino, Enrico / Peila, Chiara / Cresi, Francesco

    Microorganisms

    2020  Volume 8, Issue 5

    Abstract: Cytomegalovirus (CMV) is the leading cause of congenital infection. Its occurrence is phenotypically heterogeneous. The type of maternal infection, primary or non-primary, is an important factor related to the symptomatic disease, the primary infection ... ...

    Abstract Cytomegalovirus (CMV) is the leading cause of congenital infection. Its occurrence is phenotypically heterogeneous. The type of maternal infection, primary or non-primary, is an important factor related to the symptomatic disease, the primary infection was long considered the only cause of severe neonatal disease. We aimed to analyze the association of primary and non-primary infection with pathological outcomes in infants and with long-term sequelae at follow-up. This was a monocentric retrospective observational study on a population of 91 infants diagnosed with a CMV infection at the Neonatal Care Unit of Neonatology at the Sant'Anna Hospital of Turin during the period of June 2005 to December 2018. Infants underwent clinical, laboratory, and neuroradiological evaluations at birth. Subsequently, the patients were monitored in an auxological, neurodevelopment, and audiological follow-up. Regarding primary vs. non-primary infection, we found a higher percentage of incidence of symptomatic and neurological localized infection, as well as long-term sequelae in the latter. However, no significant difference between the two populations was found. We underline the possibility of re-infection in previously immunized mothers (non-primary infection) with unfavorable neonatal and long-term outcomes.
    Language English
    Publishing date 2020-05-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms8050786
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Detection of SARS-CoV-2 in Milk From COVID-19 Positive Mothers and Follow-Up of Their Infants.

    Bertino, Enrico / Moro, Guido Eugenio / De Renzi, Giuseppe / Viberti, Giuseppina / Cavallo, Rossana / Coscia, Alessandra / Rubino, Carlotta / Tonetto, Paola / Sottemano, Stefano / Campagnoli, Maria Francesca / Soldi, Antonella / Mostert, Michael / Cresi, Francesco / Lembo, David

    Frontiers in pediatrics

    2020  Volume 8, Page(s) 597699

    Abstract: Background: ...

    Abstract Background:
    Keywords covid19
    Language English
    Publishing date 2020-10-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2020.597699
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Effects on Gastroesophageal Reflux of Donkey Milk-Derived Human Milk Fortifier Versus Standard Fortifier in Preterm Newborns: Additional Data from the FortiLat Study.

    Cresi, Francesco / Maggiora, Elena / Pirra, Alice / Tonetto, Paola / Rubino, Carlotta / Cavallarin, Laura / Giribaldi, Marzia / Moro, Guido E / Peila, Chiara / Coscia, Alessandra

    Nutrients

    2020  Volume 12, Issue 7

    Abstract: Background: Feeding intolerance is a frequent diagnosis in very preterm infants. As seen in the FortiLat trial, human milk fortification with the new donkey milk-derived human milk fortifier (DF) seems to improve feeding tolerance in these infants. The ... ...

    Abstract Background: Feeding intolerance is a frequent diagnosis in very preterm infants. As seen in the FortiLat trial, human milk fortification with the new donkey milk-derived human milk fortifier (DF) seems to improve feeding tolerance in these infants. The aim of this study was to evaluate the effects of using the DF compared with bovine milk-derived fortifier (BF) on gastroesophageal reflux (GER) in very low birth weight (VLBW) infants.
    Methods: Over a total of 156 preterm infants were enrolled into the FortiLat trial (GA <32 weeks and birth weight <1500 g) and randomized into the BF arm or DF arm, and we selected all infants with clinical signs of GER and cardiorespiratory (CR) symptoms. All the infants underwent CR and multichannel intraluminal impedance and pH (MII/pH) monitoring associated with gastric ultrasound to evaluate GER and gastric emptying time.
    Results: 10 infants were enrolled, and 5 were in the DF arm. At MII/pH, infants enrolled into the DF arm showed a lower GER frequency than BF arm infants (
    Conclusion: The use of donkey-derived human milk fortifier reduced the GER frequency and consequently should be recommended in infants with feeding intolerance.
    MeSH term(s) Animals ; Cattle ; Equidae ; Female ; Food, Fortified ; Gastroesophageal Reflux/etiology ; Gastroesophageal Reflux/prevention & control ; Humans ; Infant ; Infant Formula ; Infant Nutritional Physiological Phenomena/physiology ; Infant, Newborn ; Infant, Very Low Birth Weight ; Male ; Milk ; Milk, Human
    Language English
    Publishing date 2020-07-18
    Publishing country Switzerland
    Document type Comparative Study ; Journal Article ; Randomized Controlled Trial
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu12072142
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Clinical use of polyvalent immunoglobulins.

    Quinti, Isabella / Pesce, Anna Maria / Bonanni, Livia / Rubino, Carlotta / Pulvirenti, Federica / Milito, Cinzia

    Blood transfusion = Trasfusione del sangue

    2013  Volume 11 Suppl 4, Page(s) s33–9

    MeSH term(s) Humans ; Immunoglobulins, Intravenous/therapeutic use ; Immunologic Factors/therapeutic use
    Chemical Substances Immunoglobulins, Intravenous ; Immunologic Factors
    Language English
    Publishing date 2013-12-12
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2135732-8
    ISSN 2385-2070 ; 0041-1787 ; 1723-2007
    ISSN (online) 2385-2070
    ISSN 0041-1787 ; 1723-2007
    DOI 10.2450/2013.007s
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 798: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

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  8. Article ; Online: Detection of SARS-CoV-2 in Milk From COVID-19 Positive Mothers and Follow-Up of Their Infants

    Bertino, Enrico / Moro, Guido Eugenio / De Renzi, Giuseppe / Viberti, Giuseppina / Cavallo, Rossana / Coscia, Alessandra / Rubino, Carlotta / Tonetto, Paola / Sottemano, Stefano / Campagnoli, Maria Francesca / Soldi, Antonella / Mostert, Michael / Cresi, Francesco / Lembo, David

    Frontiers in Pediatrics

    2020  Volume 8

    Keywords covid19
    Publisher Frontiers Media SA
    Publishing country ch
    Document type Article ; Online
    ZDB-ID 2711999-3
    ISSN 2296-2360
    ISSN 2296-2360
    DOI 10.3389/fped.2020.597699
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: SARS-CoV-2 in Human Breast Milk and Neonatal Outcome: A Collaborative Study

    Bertino, Enrico Moro Guido Eugenio De Renzi Giuseppe Viberti Giuseppina Cavallo Rossana Coscia Alessandra Rubino Carlotta Tonetto Paola Sottemano Stefano Campagnoli Maria Francesca Soldi Antonella Mostert Michael Cresi Francesco Lembo David Group Collaborative Research Grouon Sars- C. O. V. in Human Milk

    Abstract: Background: In the current COVID-19 pandemic caused by the SARS-Coronavirus-2 (SARS-CoV-2) it is important to understand if breast milk may be a vehicle of ... ...

    Abstract Background: In the current COVID-19 pandemic caused by the SARS-Coronavirus-2 (SARS-CoV-2) it is important to understand if breast milk may be a vehicle of infe
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #1489
    Database COVID19

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  10. Article ; Online: SARS-CoV-2 in Human Breast Milk and Neonatal Outcome

    Bertino, Enrico / Moro, Guido Eugenio / De Renzi, Giuseppe / Viberti, Giuseppina / Cavallo, Rossana / Coscia, Alessandra / Rubino, Carlotta / Tonetto, Paola / Sottemano, Stefano / Campagnoli, Maria Francesca / Soldi, Antonella / Mostert, Michael / Cresi, Francesco / Lembo, David / Group, Collaborative Research Group on SAR

    SSRN Electronic Journal ; ISSN 1556-5068

    A Collaborative Study

    2020  

    Keywords covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.2139/ssrn.3611974
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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