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  1. Article ; Online: Hair loss is a symptom of many complex medical and psychological problems.

    Rudnicka, Lidia

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2023  Volume 37, Issue 8, Page(s) 1460–1461

    MeSH term(s) Humans ; Alopecia/diagnosis ; Alopecia/etiology
    Language English
    Publishing date 2023-11-09
    Publishing country England
    Document type Editorial
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.19283
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A ranking of treatment efficacy in alopecia areata is not possible without head-to-head studies.

    Rudnicka, Lidia / Olszewska, Malgorzata

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2024  Volume 38, Issue 5, Page(s) 786–787

    MeSH term(s) Alopecia Areata/drug therapy ; Humans ; Treatment Outcome
    Language English
    Publishing date 2024-04-25
    Publishing country England
    Document type Letter ; Journal Article
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.19964
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Atlas of trichoscopy

    Rudnicka, Lidia / Olszewska, Malgorzata / Rakowska, Adriana

    dermoscopy in hair and scalp disease

    2012  

    Author's details Lidia Rudnicka ; Malgorzata Olszewska ; Adriana Rakowska
    Keywords Hair--Diseases--Diagnosis ; Scalp--Diseases--Diagnosis
    Language English
    Size XIV, 507 S. : zahlr. Ill., 28 cm
    Publisher Springer
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT017511831
    ISBN 978-1-4471-4485-4 ; 9781447144861 ; 1-4471-4485-6 ; 1447144864
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Safety of Janus Kinase inhibitors in Patients with Alopecia Areata: A Systematic Review.

    Papierzewska, Małgorzata / Waśkiel-Burnat, Anna / Rudnicka, Lidia

    Clinical drug investigation

    2023  Volume 43, Issue 5, Page(s) 325–334

    Abstract: Background and objectives: Janus kinase (JAK) inhibitors are emerging as a therapeutic option for alopecia areata. The risk of potential adverse events is currently debated. In particular, several safety data for JAK inhibitors are extrapolated from a ... ...

    Abstract Background and objectives: Janus kinase (JAK) inhibitors are emerging as a therapeutic option for alopecia areata. The risk of potential adverse events is currently debated. In particular, several safety data for JAK inhibitors are extrapolated from a single study in elderly patients with rheumatoid arthritis treated with tofacitinib or adalimumab/etanercept as a comparator. The population of patients with alopecia areata is clinically and immunologically different from persons with rheumatoid arthritis and tumor necrosis factor (TNF) inhibitors are not effective in these patients. The objective of this systematic review was to analyze available data on the safety of various JAK inhibitors in patients with alopecia areata.
    Methods: The systematic review was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A literature review was performed by searching PubMed, Scopus and EBSCO databases with the last search on March 13, 2023.
    Results: In total, 36 studies were included. The frequency and odds ratio (OR) for most common adverse events versus placebo were: for baricitinib hypercholesterolemia (18.2% vs 10.5%, OR = 1.9) and headache (6.1% vs 5.1%, OR = 1.2), for brepocitinib elevated creatinine level (27.7% vs 4.3%, OR = 8.6) and acne (10.6% vs 4.3%, OR = 2.7), for ritlecitinib acne (10.4% vs 4.3%, OR = 2.6) and headache (12.5% vs 10.6%, OR = 1.2) and for deuruxolitinib headache (21.4% vs 9.1%, OR = 2.7) and acne (13.6% vs 4.5%, OR = 3.3). The respective numbers for upper respiratory infections were: baricitinib (7.3% vs 7.0%, OR = 1.0) and brepocitinib (23.4% vs 10.6%, OR = 2.6); for nasopharyngitis: ritlecitinib (12.5% vs 12.8%, OR = 1.0) and deuruxolitinib (14.6% vs 2.3%, OR = 7.3).
    Conclusions: The most common side effects of JAK inhibitors in patients with alopecia areata were headache and acne. The OR for upper respiratory tract infections varied from over 7-fold increased to comparable to placebo. The risk of serious adverse events was not increased.
    MeSH term(s) Humans ; Aged ; Janus Kinase Inhibitors/adverse effects ; Alopecia Areata/drug therapy ; Alopecia Areata/chemically induced ; Protein Kinase Inhibitors/adverse effects ; Arthritis, Rheumatoid/drug therapy ; Alopecia/drug therapy
    Chemical Substances Janus Kinase Inhibitors ; baricitinib (ISP4442I3Y) ; Protein Kinase Inhibitors
    Language English
    Publishing date 2023-05-03
    Publishing country New Zealand
    Document type Systematic Review
    ZDB-ID 1220136-4
    ISSN 1179-1918 ; 0114-2402 ; 1173-2563
    ISSN (online) 1179-1918
    ISSN 0114-2402 ; 1173-2563
    DOI 10.1007/s40261-023-01260-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Autoinflammatory Keratinization Diseases-The Concept, Pathophysiology, and Clinical Implications.

    Blicharz, Leszek / Czuwara, Joanna / Rudnicka, Lidia / Torrelo, Antonio

    Clinical reviews in allergy & immunology

    2023  Volume 65, Issue 3, Page(s) 377–402

    Abstract: Recent advances in medical genetics elucidated the background of diseases characterized by superficial dermal and epidermal inflammation with resultant aberrant keratosis. This led to introducing the term autoinflammatory keratinization diseases ... ...

    Abstract Recent advances in medical genetics elucidated the background of diseases characterized by superficial dermal and epidermal inflammation with resultant aberrant keratosis. This led to introducing the term autoinflammatory keratinization diseases encompassing entities in which monogenic mutations cause spontaneous activation of the innate immunity and subsequent disruption of the keratinization process. Originally, autoinflammatory keratinization diseases were attributed to pathogenic variants of CARD14 (generalized pustular psoriasis with concomitant psoriasis vulgaris, palmoplantar pustulosis, type V pityriasis rubra pilaris), IL36RN (generalized pustular psoriasis without concomitant psoriasis vulgaris, impetigo herpetiformis, acrodermatitis continua of Hallopeau), NLRP1 (familial forms of keratosis lichenoides chronica), and genes of the mevalonate pathway, i.e., MVK, PMVK, MVD, and FDPS (porokeratosis). Since then, endotypes underlying novel entities matching the concept of autoinflammatory keratinization diseases have been discovered (mutations of JAK1, POMP, and EGFR). This review describes the concept and pathophysiology of autoinflammatory keratinization diseases and outlines the characteristic clinical features of the associated entities. Furthermore, a novel term for NLRP1-associated autoinflammatory disease with epithelial dyskeratosis (NADED) describing the spectrum of autoinflammatory keratinization diseases secondary to NLRP1 mutations is proposed.
    MeSH term(s) Humans ; Psoriasis/genetics ; Psoriasis/pathology ; Inflammation/genetics ; Mutation ; Immunity, Innate ; Keratosis ; Guanylate Cyclase/genetics ; Membrane Proteins ; CARD Signaling Adaptor Proteins/genetics ; Interleukins/genetics
    Chemical Substances CARD14 protein, human (EC 4.6.1.-) ; Guanylate Cyclase (EC 4.6.1.2) ; Membrane Proteins ; CARD Signaling Adaptor Proteins ; IL36RN protein, human ; Interleukins
    Language English
    Publishing date 2023-12-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1239045-8
    ISSN 1559-0267 ; 1080-0549
    ISSN (online) 1559-0267
    ISSN 1080-0549
    DOI 10.1007/s12016-023-08971-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Ocular involvement in autoimmune bullous diseases.

    Kurzeja, Marta / Olszewska, Malgorzata / Grzybowski, Andrzej / Rudnicka, Lidia

    Clinics in dermatology

    2023  Volume 41, Issue 4, Page(s) 481–490

    Abstract: Autoimmune bullous diseases represent a heterogenous group of disorders caused by autoantibodies against adhesion molecules; the location of the target protein determines the level of cleft formation. The spectrum of ocular lesions in autoimmune bullous ... ...

    Abstract Autoimmune bullous diseases represent a heterogenous group of disorders caused by autoantibodies against adhesion molecules; the location of the target protein determines the level of cleft formation. The spectrum of ocular lesions in autoimmune bullous diseases can range from mild symptoms to severe involvement with sight impairment and even, in some cases, blindness. In pemphigus vulgaris, the prevalence of ocular involvement has been reported to be between 7% and 26%. The most common clinical sign of ocular pemphigus vulgaris is bilateral conjunctivitis with hyperemia. Ocular involvement also occurs in 41% to 70% of patients with paraneoplastic pemphigus. The main ocular manifestations are bilateral cicatrizing conjunctivitis with symblepharon formation, and shortening of the fornices. In mucous membrane pemphigoid, ocular involvement is seen in 61% to 70% of patients; the most frequent ocular finding is cicatricial conjunctivitis. Patients with autoimmune bullous diseases having common ocular involvement should be assessed by an ophthalmologist to avoid serious complications. Diagnostic procedures and treatment require multidisciplinary care based on the close cooperation between dermatologists and ophthalmologists.
    MeSH term(s) Humans ; Pemphigus/drug therapy ; Autoimmune Diseases/diagnosis ; Skin Diseases, Vesiculobullous/complications ; Skin Diseases, Vesiculobullous/diagnosis ; Pemphigoid, Benign Mucous Membrane/complications ; Pemphigoid, Benign Mucous Membrane/diagnosis ; Pemphigoid, Benign Mucous Membrane/drug therapy ; Conjunctivitis
    Language English
    Publishing date 2023-08-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1064149-x
    ISSN 1879-1131 ; 0738-081X
    ISSN (online) 1879-1131
    ISSN 0738-081X
    DOI 10.1016/j.clindermatol.2023.08.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Trichoscopy of Androgenetic Alopecia: A Systematic Review.

    Kuczara, Agata / Waśkiel-Burnat, Anna / Rakowska, Adriana / Olszewska, Małgorzata / Rudnicka, Lidia

    Journal of clinical medicine

    2024  Volume 13, Issue 7

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2024-03-28
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13071962
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Dermatoscopy of Cutaneous Lichen Planus - Attempt to Translate Metaphoric Terminology Into Descriptive Terminology.

    Szykut-Badaczewska, Agata / Sikora, Mariusz / Rudnicka, Lidia / Kittler, Harald

    Dermatology practical & conceptual

    2023  Volume 13, Issue 3

    Abstract: Introduction: Dermatoscopy is gaining appreciation in assisting the diagnosis of inflammatory dermatoses (inflammoscopy). Lichen planus (LP) is a common inflammatory skin disease with characteristic dermatoscopic features. Over the last few years, ... ...

    Abstract Introduction: Dermatoscopy is gaining appreciation in assisting the diagnosis of inflammatory dermatoses (inflammoscopy). Lichen planus (LP) is a common inflammatory skin disease with characteristic dermatoscopic features. Over the last few years, numerous articles were published on the dermatoscopy of LP and a high number of terms have been used to describe the dermatoscopic features of this disease.
    Objectives: The objective of this study was to review the literature on the dermatoscopy of LP and to re-evaluate the published descriptions in the light of the 2019 expert consensus on the terminology of dermatoscopy for non-neoplastic skin diseases.
    Methods: We searched the PubMed database using the keywords 'lichen planus and dermatoscopy', 'lichen planus and dermoscopy', 'lichen planus and epiluminescence microscopy', and 'lichen planus and inflammoscopy'.
    Results: Of 408 articles retrieved, we selected 67 articles for full-text review, and finally included 58 articles, mostly case reports or small case series, comprising 572 patients with LP. We identified 118 different terms or short descriptions that were used to characterize the dermatoscopy of LP and redescribed them according to International Dermoscopy Society consensus paper. Frequently, authors applied various terms or descriptions to variants of the same feature. Although reported under different designations, Wickham striae were the most consistent dermatoscopic feature of LP. Other characteristics of LP, such as vascular patterns, pigmented structures and follicular findings were less consistent or depended on skin type, anatomic site, disease stage and applied treatment.
    Conclusions: While Wickham striae are the single most important clue for the diagnosis, other dermatoscopic characteristics of LP are less consistent. Based on the descriptions published in the literature we established a dictionary of useful terms for the description of LP that is consistent with the terminology suggested by the recent consensus conference.
    Language English
    Publishing date 2023-07-01
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 2685397-8
    ISSN 2160-9381
    ISSN 2160-9381
    DOI 10.5826/dpc.1303a174
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Topical proactive therapy in dermatology. A scoping review.

    Makowska, Karolina / Nowaczyk, Joanna / Samochocki, Zbigniew / Blicharz, Leszek / Rudnicka, Lidia

    Postepy dermatologii i alergologii

    2023  Volume 40, Issue 4, Page(s) 510–517

    Abstract: The term 'proactive therapy' refers to a long-term management of clinically intact skin in previously disease-affected areas. This method was initially implemented in atopic dermatitis to maintain the remission and decrease the risk of exacerbations. ... ...

    Abstract The term 'proactive therapy' refers to a long-term management of clinically intact skin in previously disease-affected areas. This method was initially implemented in atopic dermatitis to maintain the remission and decrease the risk of exacerbations. Proactive therapy aims to limit the need for reactive treatment and improve the patients' quality of life. A proactive approach is likely to be adopted for other relapsing and inflammatory skin conditions in the future. This scoping review aims to identify dermatological conditions to be treated with the proactive approach, evaluate the available evidence for its efficacy and safety, as well as highlight the research gaps.
    Language English
    Publishing date 2023-09-01
    Publishing country Poland
    Document type Journal Article ; Review
    ZDB-ID 2596142-1
    ISSN 1642-395X
    ISSN 1642-395X
    DOI 10.5114/ada.2023.129454
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Trichoscopy Features of Allergic Contact Dermatitis of the Scalp: A Prospective Case Series.

    Makowska, Katarzyna / Golińska, Joanna / Sar-Pomian, Marta / Rudnicka, Lidia

    Dermatitis : contact, atopic, occupational, drug

    2023  Volume 34, Issue 3, Page(s) 265–268

    MeSH term(s) Humans ; Scalp ; Dermatitis, Allergic Contact/diagnosis ; Dermatitis, Allergic Contact/etiology ; Patch Tests ; Scalp Dermatoses/etiology
    Language English
    Publishing date 2023-01-02
    Publishing country United States
    Document type Letter
    ZDB-ID 2144723-8
    ISSN 2162-5220 ; 1532-8163 ; 1710-3568
    ISSN (online) 2162-5220 ; 1532-8163
    ISSN 1710-3568
    DOI 10.1097/DER.0000000000000832
    Database MEDical Literature Analysis and Retrieval System OnLINE

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