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  1. Article ; Online: Operative and Technical Modifications to the Coriolis® µ Air Sampler That Improve Sample Recovery and Biosafety During Microbiological Air Sampling.

    Rufino de Sousa, Nuno / Shen, Lei / Silcott, David / Call, Charles J / Rothfuchs, Antonio Gigliotti

    Annals of work exposures and health

    2020  Volume 64, Issue 8, Page(s) 852–865

    Abstract: Detecting infectious aerosols is central for gauging and countering airborne threats. In this regard, the Coriolis® µ cyclonic air sampler is a practical, commercial collector that can be used with various analysis methods to monitor pathogens in air. ... ...

    Abstract Detecting infectious aerosols is central for gauging and countering airborne threats. In this regard, the Coriolis® µ cyclonic air sampler is a practical, commercial collector that can be used with various analysis methods to monitor pathogens in air. However, information on how to operate this unit under optimal sampling and biosafety conditions is limited. We investigated Coriolis performance in aerosol dispersal experiments with polystyrene microspheres and Bacillus globigii spores. We report inconsistent sample recovery from the collector cone due to loss of material when sampling continuously for more than 30 min. Introducing a new collector cone every 10 min improved this shortcoming. Moreover, we found that several surfaces on the device become contaminated during sampling. Adapting a high efficiency particulate air-filter system to the Coriolis prevented contamination without altering collection efficiency or tactical deployment. A Coriolis modified with these operative and technical improvements was used to collect aerosols carrying microspheres released inside a Biosafety Level-3 laboratory during simulations of microbiological spills and aerosol dispersals. In summary, we provide operative and technical solutions to the Coriolis that optimize microbiological air sampling and improve biosafety.
    MeSH term(s) Aerosols/analysis ; Air Pollutants ; Bacillus ; Containment of Biohazards ; Dust ; Humans ; Occupational Exposure/analysis
    Chemical Substances Aerosols ; Air Pollutants ; Dust
    Keywords covid19
    Language English
    Publishing date 2020-05-29
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2885096-8
    ISSN 2398-7316 ; 2398-7308
    ISSN (online) 2398-7316
    ISSN 2398-7308
    DOI 10.1093/annweh/wxaa053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: SARS-CoV-2 promotes microglial synapse elimination in human brain organoids.

    Samudyata / Oliveira, Ana O / Malwade, Susmita / Rufino de Sousa, Nuno / Goparaju, Sravan K / Gracias, Jessica / Orhan, Funda / Steponaviciute, Laura / Schalling, Martin / Sheridan, Steven D / Perlis, Roy H / Rothfuchs, Antonio G / Sellgren, Carl M

    Molecular psychiatry

    2022  Volume 27, Issue 10, Page(s) 3939–3950

    Abstract: Neuropsychiatric manifestations are common in both the acute and post-acute phase of SARS-CoV-2 infection, but the mechanisms of these effects are unknown. In a newly established brain organoid model with innately developing microglia, we demonstrate ... ...

    Abstract Neuropsychiatric manifestations are common in both the acute and post-acute phase of SARS-CoV-2 infection, but the mechanisms of these effects are unknown. In a newly established brain organoid model with innately developing microglia, we demonstrate that SARS-CoV-2 infection initiate neuronal cell death and cause a loss of post-synaptic termini. Despite limited neurotropism and a decelerating viral replication, we observe a threefold increase in microglial engulfment of postsynaptic termini after SARS-CoV-2 exposure. We define the microglial responses to SARS-CoV-2 infection by single cell transcriptomic profiling and observe an upregulation of interferon-responsive genes as well as genes promoting migration and synapse engulfment. To a large extent, SARS-CoV-2 exposed microglia adopt a transcriptomic profile overlapping with neurodegenerative disorders that display an early synapse loss as well as an increased incident risk after a SARS-CoV-2 infection. Our results reveal that brain organoids infected with SARS-CoV-2 display disruption in circuit integrity via microglia-mediated synapse elimination and identifies a potential novel mechanism contributing to cognitive impairments in patients recovering from COVID-19.
    MeSH term(s) Humans ; SARS-CoV-2 ; Organoids ; Microglia ; COVID-19 ; Brain ; Presynaptic Terminals
    Language English
    Publishing date 2022-10-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1330655-8
    ISSN 1476-5578 ; 1359-4184
    ISSN (online) 1476-5578
    ISSN 1359-4184
    DOI 10.1038/s41380-022-01786-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Plaque-forming units from air samples: Letter to Editor. Re: Jefferson et al., Indoor Air, 2022.

    Rufino de Sousa, Nuno / Steponaviciute, Laura / Margerie, Lucille / Nissen, Karolina / Kjellin, Midori / Reinius, Björn / Salaneck, Erik / Udekwu, Klas I / Rothfuchs, Antonio Gigliotti

    Indoor air

    2022  Volume 32, Issue 11, Page(s) e13169

    MeSH term(s) Air Pollution, Indoor/analysis ; Air Microbiology ; Air Pollutants/analysis
    Chemical Substances Air Pollutants
    Language English
    Publishing date 2022-11-27
    Publishing country England
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1081722-0
    ISSN 1600-0668 ; 0905-6947
    ISSN (online) 1600-0668
    ISSN 0905-6947
    DOI 10.1111/ina.13169
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  4. Article ; Online: Corrigendum. Re: de Sousa, N.R., et al., 2022. Detection and isolation of airborne SARS-CoV-2 in a hospital setting. Indoor air, 32(3), e13023.

    Rufino de Sousa, Nuno / Steponaviciute, Laura / Margerie, Lucille / Nissen, Karolina / Kjellin, Midori / Reinius, Björn / Salaneck, Erik / Udekwu, Klas I / Rothfuchs, Antonio Gigliotti

    Indoor air

    2022  Volume 32, Issue 8, Page(s) e13085

    MeSH term(s) Air Pollution, Indoor ; COVID-19 ; Hospitals ; Humans ; SARS-CoV-2
    Language English
    Publishing date 2022-08-28
    Publishing country England
    Document type Letter ; Published Erratum
    ZDB-ID 1081722-0
    ISSN 1600-0668 ; 0905-6947
    ISSN (online) 1600-0668
    ISSN 0905-6947
    DOI 10.1111/ina.13085
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  5. Article ; Online: Detection and isolation of airborne SARS-CoV-2 in a hospital setting.

    Rufino de Sousa, Nuno / Steponaviciute, Laura / Margerie, Lucille / Nissen, Karolina / Kjellin, Midori / Reinius, Björn / Salaneck, Erik / Udekwu, Klas I / Rothfuchs, Antonio Gigliotti

    Indoor air

    2022  Volume 32, Issue 3, Page(s) e13023

    Abstract: Transmission mechanisms for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are incompletely understood. In particular, aerosol transmission remains unclear, with viral detection in air and demonstration of its infection potential being ... ...

    Abstract Transmission mechanisms for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are incompletely understood. In particular, aerosol transmission remains unclear, with viral detection in air and demonstration of its infection potential being actively investigated. To this end, we employed a novel electrostatic collector to sample air from rooms occupied by COVID-19 patients in a major Swedish hospital. Electrostatic air sampling in conjunction with extraction-free, reverse-transcriptase polymerase chain reaction (hid-RT-PCR) enabled detection of SARS-CoV-2 in air from patient rooms (9/22; 41%) and adjoining anterooms (10/22; 45%). Detection with hid-RT-PCR was concomitant with viral RNA presence on the surface of exhaust ventilation channels in patients and anterooms more than 2 m from the COVID-19 patient. Importantly, it was possible to detect active SARS-CoV-2 particles from room air, with a total of 496 plaque-forming units (PFUs) being isolated, establishing the presence of infectious, airborne SARS-CoV-2 in rooms occupied by COVID-19 patients. Our results support circulation of SARS-CoV-2 via aerosols and urge the revision of existing infection control frameworks to include airborne transmission.
    MeSH term(s) Air Pollution, Indoor ; COVID-19 ; Hospitals ; Humans ; RNA, Viral/analysis ; SARS-CoV-2
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2022-03-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1081722-0
    ISSN 1600-0668 ; 0905-6947
    ISSN (online) 1600-0668
    ISSN 0905-6947
    DOI 10.1111/ina.13023
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  6. Article ; Online: A fieldable electrostatic air sampler enabling tuberculosis detection in bioaerosols.

    Rufino de Sousa, Nuno / Sandström, Niklas / Shen, Lei / Håkansson, Kathleen / Vezozzo, Rafaella / Udekwu, Klas I / Croda, Julio / Rothfuchs, Antonio Gigliotti

    Tuberculosis (Edinburgh, Scotland)

    2019  Volume 120, Page(s) 101896

    Abstract: Tuberculosis (TB) infects about 25% of the world population and claims more human lives than any other infectious disease. TB is spread by inhalation of aerosols containing viable Mycobacterium tuberculosis expectorated or exhaled by patients with active ...

    Abstract Tuberculosis (TB) infects about 25% of the world population and claims more human lives than any other infectious disease. TB is spread by inhalation of aerosols containing viable Mycobacterium tuberculosis expectorated or exhaled by patients with active pulmonary disease. Air-sampling technology could play an important role in TB control by enabling the detection of airborne M. tuberculosis, but tools that are easy to use and scalable in TB hotspots are lacking. We developed an electrostatic air sampler termed the TB Hotspot DetectOR (THOR) and investigated its performance in laboratory aerosol experiments and in a prison hotspot of TB transmission. We show that THOR collects aerosols carrying microspheres, Bacillus globigii spores and M. bovis BCG, concentrating these microparticles onto a collector piece designed for subsequent detection analysis. The unit was also successfully operated in the complex setting of a prison hotspot, enabling detection of a molecular signature for M. tuberculosis in the cough of inmates. Future deployment of this device may lead to a measurable impact on TB case-finding by screening individuals through the aerosols they generate.
    MeSH term(s) Aerosols ; Air Microbiology ; Bacteriological Techniques ; Cough/microbiology ; DNA, Bacterial/genetics ; Environmental Monitoring ; Humans ; Mycobacterium bovis/genetics ; Mycobacterium bovis/isolation & purification ; Mycobacterium tuberculosis/genetics ; Mycobacterium tuberculosis/isolation & purification ; Polymerase Chain Reaction ; Prisons ; Static Electricity ; Tuberculosis, Pulmonary/diagnosis ; Tuberculosis, Pulmonary/microbiology ; Tuberculosis, Pulmonary/transmission
    Chemical Substances Aerosols ; DNA, Bacterial
    Language English
    Publishing date 2019-12-24
    Publishing country Scotland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2046804-0
    ISSN 1873-281X ; 1472-9792
    ISSN (online) 1873-281X
    ISSN 1472-9792
    DOI 10.1016/j.tube.2019.101896
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    Uh II Zs.221: Show issues Location:
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  7. Article ; Online: Massive and rapid COVID-19 testing is feasible by extraction-free SARS-CoV-2 RT-PCR.

    Smyrlaki, Ioanna / Ekman, Martin / Lentini, Antonio / Rufino de Sousa, Nuno / Papanicolaou, Natali / Vondracek, Martin / Aarum, Johan / Safari, Hamzah / Muradrasoli, Shaman / Rothfuchs, Antonio Gigliotti / Albert, Jan / Högberg, Björn / Reinius, Björn

    Nature communications

    2020  Volume 11, Issue 1, Page(s) 4812

    Abstract: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is commonly diagnosed by reverse transcription polymerase chain reaction (RT-PCR) to detect viral RNA in patient samples, but RNA extraction ... ...

    Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is commonly diagnosed by reverse transcription polymerase chain reaction (RT-PCR) to detect viral RNA in patient samples, but RNA extraction constitutes a major bottleneck in current testing. Methodological simplification could increase diagnostic availability and efficiency, benefitting patient care and infection control. Here, we describe methods circumventing RNA extraction in COVID-19 testing by performing RT-PCR directly on heat-inactivated or lysed samples. Our data, including benchmarking using 597 clinical patient samples and a standardised diagnostic system, demonstrate that direct RT-PCR is viable option to extraction-based tests. Using controlled amounts of active SARS-CoV-2, we confirm effectiveness of heat inactivation by plaque assay and evaluate various generic buffers as transport medium for direct RT-PCR. Significant savings in time and cost are achieved through RNA-extraction-free protocols that are directly compatible with established PCR-based testing pipelines. This could aid expansion of COVID-19 testing.
    MeSH term(s) Benchmarking ; Betacoronavirus/genetics ; Betacoronavirus/isolation & purification ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Clinical Laboratory Techniques/standards ; Clinical Laboratory Techniques/statistics & numerical data ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/virology ; DNA Primers/genetics ; Hot Temperature ; Humans ; Pandemics ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/virology ; RNA, Viral/genetics ; RNA, Viral/isolation & purification ; Reverse Transcriptase Polymerase Chain Reaction/methods ; Reverse Transcriptase Polymerase Chain Reaction/standards ; Reverse Transcriptase Polymerase Chain Reaction/statistics & numerical data ; SARS-CoV-2 ; Sensitivity and Specificity ; Sweden/epidemiology ; Viral Plaque Assay/methods
    Chemical Substances DNA Primers ; RNA, Viral
    Keywords covid19
    Language English
    Publishing date 2020-09-23
    Publishing country England
    Document type Comparative Study ; Evaluation Study ; Journal Article ; Research Support, Non-U.S. Gov't ; Validation Study
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-020-18611-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Massive and rapid COVID-19 testing is feasible by extraction-free SARS-CoV-2 RT-PCR

    Smyrlaki, Ioanna / Ekman, Martin / Lentini, Antonio / Rufino de Sousa, Nuno / Papanicolaou, Natali / Vondracek, Martin / Aarum, Johan / Safari, Hamzah / Muradrasoli, Shaman / Rothfuchs, Antonio Gigliotti / Albert, Jan / Högberg, Björn / Reinius, Björn

    Nature Communications

    2020  Volume 11, Issue 1

    Abstract: Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is commonly diagnosed by reverse transcription polymerase chain reaction (RT-PCR) to detect viral RNA in patient samples, but RNA ... ...

    Abstract Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is commonly diagnosed by reverse transcription polymerase chain reaction (RT-PCR) to detect viral RNA in patient samples, but RNA extraction constitutes a major bottleneck in current testing. Methodological simplification could increase diagnostic availability and efficiency, benefitting patient care and infection control. Here, we describe methods circumventing RNA extraction in COVID-19 testing by performing RT-PCR directly on heat-inactivated or lysed samples. Our data, including benchmarking using 597 clinical patient samples and a standardised diagnostic system, demonstrate that direct RT-PCR is viable option to extraction-based tests. Using controlled amounts of active SARS-CoV-2, we confirm effectiveness of heat inactivation by plaque assay and evaluate various generic buffers as transport medium for direct RT-PCR. Significant savings in time and cost are achieved through RNA-extraction-free protocols that are directly compatible with established PCR-based testing pipelines. This could aid expansion of COVID-19 testing.
    Keywords General Biochemistry, Genetics and Molecular Biology ; General Physics and Astronomy ; General Chemistry ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2553671-0
    ISSN 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-020-18611-5
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: A global metagenomic map of urban microbiomes and antimicrobial resistance

    Danko, David / Bezdan, Daniela / Afshin, Evan E / Ahsanuddin, Sofia / Bhattacharya, Chandrima / Butler, Daniel J / Chng, Kern Rei / Donnellan, Daisy / Hecht, Jochen / Jackson, Katelyn / Kuchin, Katerina / Karasikov, Mikhail / Lyons, Abigail / Mak, Lauren / Meleshko, Dmitry / Mustafa, Harun / Mutai, Beth / Neches, Russell Y / Ng, Amanda /
    Nikolayeva, Olga / Nikolayeva, Tatyana / Png, Eileen / Ryon, Krista A / Sanchez, Jorge L / Shaaban, Heba / Sierra, Maria A / Thomas, Dominique / Young, Ben / Abudayyeh, Omar O / Alicea, Josue / Bhattacharyya, Malay / Blekhman, Ran / Castro-Nallar, Eduardo / Cañas, Ana M / Chatziefthimiou, Aspassia D / Crawford, Robert W / De Filippis, Francesca / Deng, Youping / Desnues, Christelle / Dias-Neto, Emmanuel / Dybwad, Marius / Elhaik, Eran / Ercolini, Danilo / Frolova, Alina / Gankin, Dennis / Gootenberg, Jonathan S / Graf, Alexandra B / Green, David C / Hajirasouliha, Iman / Hastings, Jaden J.A / Hernandez, Mark / Iraola, Gregorio / Jang, Soojin / Kahles, Andre / Kelly, Frank J / Knights, Kaymisha / Kyrpides, Nikos C / Łabaj, Paweł P / Lee, Patrick K.H / Leung, Marcus H.Y / Ljungdahl, Per O / Mason-Buck, Gabriella / McGrath, Ken / Meydan, Cem / Mongodin, Emmanuel F / Moraes, Milton Ozorio / Nagarajan, Niranjan / Nieto-Caballero, Marina / Noushmehr, Houtan / Oliveira, Manuela / Ossowski, Stephan / Osuolale, Olayinka O / Özcan, Orhan / Paez-Espino, David / Rascovan, Nicolás / Richard, Hugues / Rätsch, Gunnar / Schriml, Lynn M / Semmler, Torsten / Sezerman, Osman U / Shi, Leming / Shi, Tieliu / Siam, Rania / Song, Le Huu / Suzuki, Haruo / Court, Denise Syndercombe / Tighe, Scott W / Tong, Xinzhao / Udekwu, Klas I / Ugalde, Juan A / Valentine, Brandon / Vassilev, Dimitar I / Vayndorf, Elena M / Velavan, Thirumalaisamy P / Wu, Jun / Zambrano, María M / Zhu, Jifeng / Zhu, Sibo / Mason, Christopher E / Abdullah, Natasha / Abraao, Marcos / Adel, Ait-hamlat / Afaq, Muhammad / Al-Quaddoomi, Faisal S / Alam, Ireen / Albuquerque, Gabriela E / Alexiev, Alex / Ali, Kalyn / Alvarado-Arnez, Lucia E / Aly, Sarh / Amachee, Jennifer / Amorim, Maria G / Ampadu, Majelia / Amran, Muhammad Al-Fath / An, Nala / Andrew, Watson / Andrianjakarivony, Harilanto / Angelov, Michael / Antelo, Verónica / Aquino, Catharine / Aranguren, Álvaro / Araujo, Luiza F / Vasquez Arevalo, Hitler Francois / Arevalo, Jenny / Arnan, Carme / Alvarado Arnez, Lucia Elena / Arredondo, Fernanda / Arthur, Matthew / Asenjo, Freddy / Aung, Thomas Saw / Auvinet, Juliette / Aventin, Nuria / Ayaz, Sadaf / Baburyan, Silva / Bakere, Abd-Manaaf / Bakhl, Katrin / Bartelli, Thais F / Batdelger, Erdenetsetseg / Baudon, François / Becher, Kevin / Bello, Carla / Benchouaia, Médine / Benisty, Hannah / Benoiston, Anne-Sophie / Benson, Joseph / Benítez, Diego / Bernardes, Juliana / Bertrand, Denis / Beurmann, Silvia / Bitard-Feildel, Tristan / Bittner, Lucie / Black, Christina / Blanc, Guillaume / Blyther, Brittany / Bode, Toni / Boeri, Julia / Boldgiv, Bazartseren / Bolzli, Kevin / Bordigoni, Alexia / Borrelli, Ciro / Bouchard, Sonia / Bouly, Jean-Pierre / Boyd, Alicia / Branco, Gabriela P / Breschi, Alessandra / Brindefalk, Björn / Brion, Christian / Briones, Alan / Buczansla, Paulina / Burke, Catherine M / Burrell, Aszia / Butova, Alina / Buttar, Irvind / Bynoe, Jalia / Bönigk, Sven / Bøifot, Kari O / Caballero, Hiram / Cai, Xiao Wen / Calderon, Dayana / Cantillo, Angela / Carbajo, Miguel / Carbone, Alessandra / Cardenas, Anais / Carrillo, Katerine / Casalot, Laurie / Castro, Sofia / Castro, Ana V / Castro, Astred / Castro, Ana Valeria B / Cawthorne, Simone / Cedillo, Jonathan / Chaker, Salama / Chalangal, Jasna / Chan, Allison / Chasapi, Anastasia I / Chatziefthimiou, Starr / Chaudhuri, Sreya Ray / Chavan, Akash Keluth / Chavez, Francisco / Chem, Gregory / Chen, Xiaoqing / Chen, Michelle / Chen, Jenn-Wei / Chernomoretz, Ariel / Chettouh, Allaeddine / Cheung, Daisy / Chicas, Diana / Chiu, Shirley / Choudhry, Hira / Chrispin, Carl / Ciaramella, Kianna / Cifuentes, Erika / Cohen, Jake / Coil, David A / Collin, Sylvie / Conger, Colleen / Conte, Romain / Corsi, Flavia / Cossio, Cecilia N / Costa, Ana F / Cuebas, Delisia / D’Alessandro, Bruno / Dahlhausen, Katherine E / Darling, Aaron E / Das, Pujita / Davenport, Lucinda B / David, Laurent / Davidson, Natalie R / Dayama, Gargi / Delmas, Stéphane / Deng, Chris K / Dequeker, Chloé / Desert, Alexandre / Devi, Monika / Dezem, Felipe S / Dias, Clara N / Donahoe, Timothy Ryan / Dorado, Sonia / Dorsey, LaShonda / Dotsenko, Valeriia / Du, Steven / Dutan, Alexandra / Eady, Naya / Eisen, Jonathan A / Elaskandrany, Miar / Epping, Lennard / Escalera-Antezana, Juan P / Ettinger, Cassie L / Faiz, Iqra / Fan, Luice / Farhat, Nadine / Faure, Emile / Fauzi, Fazlina / Feigin, Charlie / Felice, Skye / Ferreira, Laís Pereira / Figueroa, Gabriel / Fleiss, Aubin / Flores, Denisse / Velasco Flores, Jhovana L / Fonseca, Marcos A.S / Foox, Jonathan / Forero, Juan Carlos / Francis, Aaishah / French, Kelly / Fresia, Pablo / Friedman, Jacob / Fuentes, Jaime J / Galipon, Josephine / Garcia, Mathilde / Garcia, Laura / García, Catalina / Geiger, Annie / Gerner, Samuel M / Ghose, Sonia L / Giang, Dao Phuong / Giménez, Matías / Giovannelli, Donato / Githae, Dedan / Gkotzis, Spyridon / Godoy, Liliana / Goldman, Samantha / Gonnet, Gaston H / Gonzalez, Juana / Gonzalez, Andrea / Gonzalez-Poblete, Camila / Gray, Andrew / Gregory, Tranette / Greselle, Charlotte / Guasco, Sophie / Guerra, Juan / Gurianova, Nika / Haehr, Wolfgang / Halary, Sebastien / Hartkopf, Felix / Hawkins-Zafarnia, Arya / Hazrin-Chong, Nur Hazlin / Helfrich, Eric / Hell, Eva / Henry, Tamera / Hernandez, Samuel / Hernandez, Pilar Lopez / Hess-Homeier, David / Hittle, Lauren E / Hoan, Nghiem Xuan / Holik, Aliaksei / Homma, Chiaki / Hoxie, Irene / Huber, Michael / Humphries, Elizabeth / Hyland, Stephanie / Hässig, Andrea / Häusler, Roland / Hüsser, Nathalie / Petit, Robert A / Iderzorig, Badamnyambuu / Igarashi, Mizuki / Iqbal, Shaikh B / Ishikawa, Shino / Ishizuka, Sakura / Islam, Sharah / Islam, Riham / Ito, Kohei / Ito, Sota / Ito, Takayuki / Ivankovic, Tomislav / Iwashiro, Tomoki / Jackson, Sarah / Jacobs, JoAnn / James, Marisano / Jaubert, Marianne / Jerier, Marie-Laure / Jiminez, Esmeralda / Jinfessa, Ayantu / De Jong, Ymke / Joo, Hyun Woo / Jospin, Guilllaume / Kajita, Takema / Ahmad Kassim, Affifah Saadah / Kato, Nao / Kaur, Amrit / Kaur, Inderjit / de Souza Gomes Kehdy, Fernanda / Khadka, Vedbar S / Khan, Shaira / Khavari, Mahshid / Ki, Michelle / Kim, Gina / Kim, Hyung Jun / Kim, Sangwan / King, Ryan J / KoLoMonaco, Giuseppe / Koag, Ellen / Kobko-Litskevitch, Nadezhda / Korshevniuk, Maryna / Kozhar, Michael / Krebs, Jonas / Kubota, Nanami / Kuklin, Andrii / Kumar, Sheelta S / Kwong, Rachel / Kwong, Lawrence / Lafontaine, Ingrid / Lago, Juliana / Lai, Tsoi Ying / Laine, Elodie / Laiola, Manolo / Lakhneko, Olha / Lamba, Isha / de Lamotte, Gerardo / Lannes, Romain / De Lazzari, Eleonora / Leahy, Madeline / Lee, Hyunjung / Lee, Yunmi / Lee, Lucy / Lemaire, Vincent / Leong, Emily / Lewandowska, Dagmara / Li, Chenhao / Liang, Weijun / Lin, Moses / Lisboa, Priscilla / Litskevitch, Anna / Liu, Eric Minwei / Liu, Tracy / Livia, Mayra Arauco / Lo, Yui Him / Losim, Sonia / Loubens, Manon / Lu, Jennifer / Lykhenko, Olexandr / Lysakova, Simona / Mahmoud, Salah / Majid, Sara Abdul / Makogon, Natalka / Maldonado, Denisse / Mallari, Krizzy / Malta, Tathiane M / Mamun, Maliha / Manoir, Dimitri / Marchandon, German / Marciniak, Natalia / Marinovic, Sonia / Marques, Brunna / Mathews, Nicole / Matsuzaki, Yuri / Matthys, Vincent / May, Madelyn / McComb, Elias / Meagher, Annabelle / Melamed, Adiell / Menary, Wayne / Mendez, Katterinne N / Mendez, Ambar / Mendy, Irène Mauricette / Meng, Irene / Menon, Ajay / Menor, Mark / Meoded, Roy / Merino, Nancy / Miah, Karishma / Mignotte, Mathilde / Miketic, Tanja / Miranda, Wilson / Mitsios, Athena / Miura, Ryusei / Miyake, Kunihiko / Moccia, Maria D / Mohan, Natasha / Mohsin, Mohammed / Moitra, Karobi / Moldes, Mauricio / Molina, Laura / Molinet, Jennifer / Molomjamts, Orgil-Erdene / Moniruzzaman, Eftar / Moon, Sookwon / de Oliveira Moraes, Isabelle / Moreno, Mario / Mosella, Maritza S / Moser, Josef W / Mozsary, Christopher / Muehlbauer, Amanda L / Muner, Oasima / Munia, Muntaha / Munim, Naimah / Muscat, Maureen / Mustac, Tatjana / Muñoz, Cristina / Nadalin, Francesca / Naeem, Areeg / Nagy-Szakal, Dorottya / Nakagawa, Mayuko / Narce, Ashanti / Nasu, Masaki / Navarrete, Irene González / Naveed, Hiba / Nazario, Bryan / Nedunuri, Narasimha Rao / Neff, Thomas / Nesimi, Aida / Ng, Wan Chiew / Ng, Synti / Nguyen, Gloria / Ngwa, Elsy / Nicolas, Agier / Nicolas, Pierre / Nika, Abdollahi / Noorzi, Hosna / Nosrati, Avigdor / Nunes, Diana N / O’Brien, Kathryn / O’Hara, Niamh B / Oken, Gabriella / Olawoyin, Rantimi A / Oliete, Javier Quilez / Olmeda, Kiara / Oluwadare, Tolulope / Oluwadare, Itunu A / Ordioni, Nils / Orpilla, Jenessa / Orrego, Jacqueline / Ortega, Melissa / Osma, Princess / Osuolale, Israel O / Osuolale, Oluwatosin M / Ota, Mitsuki / Oteri, Francesco / Oto, Yuya / Ounit, Rachid / Ouzounis, Christos A / Pakrashi, Subhamitra / Paras, Rachel / Pardo-Este, Coral / Park, Young-Ja / Pastuszek, Paulina / Patel, Suraj / Pathmanathan, Jananan / Patrignani, Andrea / Perez, Manuel / Peros, Ante / Persaud, Sabrina / Peters, Anisia / Phillips, Adam / Pineda, Lisbeth / Pizzi, Melissa P / Plaku, Alma / Plaku, Alketa / Pompa-Hogan, Brianna / Portilla, María Gabriela / Posada, Leonardo / Priestman, Max / Prithiviraj, Bharath / Priya, Sambhawa / Pugdeethosal, Phanthira / Pugh, Catherine E / Pulatov, Benjamin / Pupiec, Angelika / Pyrshev, Kyrylo / Qing, Tao / Rahiel, Saher / Rahmatulloev, Savlatjon / Rajendran, Kannan / Ramcharan, Aneisa / Ramirez-Rojas, Adan / Rana, Shahryar / Ratnanandan, Prashanthi / Read, Timothy D / Rehrauer, Hubert / Richer, Renee / Rivera, Alexis / Rivera, Michelle / Robertiello, Alessandro / Robinson, Courtney / Rodríguez, Paula / Rojas, Nayra Aguilar / Roldán, Paul / Rosario, Anyelic / Roth, Sandra / Ruiz, Maria / Boja Ruiz, Stephen Eduard / Russell, Kaitlan / Rybak, Mariia / Sabedot, Thais S / Sabina, Mahfuza / Saito, Ikuto / Saito, Yoshitaka / Malca Salas, Gustavo Adolfo / Salazar, Cecilia / San, Kaung Myat / Sanchez, Jorge / Sanchir, Khaliun / Sankar, Ryan / de Souza Santos, Paulo Thiago / Saravi, Zulena / Sasaki, Kai / Sato, Yuma / Sato, Masaki / Sato, Seisuke / Sato, Ryo / Sato, Kaisei / Sayara, Nowshin / Schaaf, Steffen / Schacher, Oli / Schinke, Anna-Lena M / Schlapbach, Ralph / Schori, Christian / Schriml, Jason R / Segato, Felipe / Sepulveda, Felipe / Serpa, Marianna S / De Sessions, Paola F / Severyn, Juan C / Shakil, Maheen / Shalaby, Sarah / Shari, Aliyah / Shim, Hyenah / Shirahata, Hikaru / Shiwa, Yuh / Da Silva, Ophélie / Silva, Jordana M / Simon, Gwenola / Singh, Shaleni K / Sluzek, Kasia / Smith, Rebecca / So, Eunice / Andreu Somavilla, Núria / Sonohara, Yuya / Rufino de Sousa, Nuno / Souza, Camila / Sperry, Jason / Sprinsky, Nicolas / Stark, Stefan G / La Storia, Antonietta / Suganuma, Kiyoshi / Suliman, Hamood / Sullivan, Jill / Supie, Arif Asyraf Md / Suzuki, Chisato / Takagi, Sora / Takahara, Fumie / Takahashi, Naoya / Takahashi, Kou / Takeda, Tomoki / Takenaka, Isabella K / Tanaka, Soma / Tang, Anyi / Man Tang, Yuk / Tarcitano, Emilio / Tassinari, Andrea / Taye, Mahdi / Terrero, Alexis / Thambiraja, Eunice / Thiébaut, Antonin / Thomas, Sade / Thomas, Andrew M / Togashi, Yuto / Togashi, Takumi / Tomaselli, Anna / Tomita, Masaru / Tomita, Itsuki / Toth, Oliver / Toussaint, Nora C / Tran, Jennifer M / Truong, Catalina / Tsonev, Stefan I / Tsuda, Kazutoshi / Tsurumaki, Takafumi / Tuz, Michelle / Tymoshenko, Yelyzaveta / Urgiles, Carmen / Usui, Mariko / Vacant, Sophie / Vann, Laura E / Velter, Fabienne / Ventorino, Valeria / Vera-Wolf, Patricia / Vicedomini, Riccardo / Suarez-Villamil, Michael A / Vincent, Sierra / Vivancos-Koopman, Renee / Wan, Andrew / Wang, Cindy / Warashina, Tomoro / Watanabe, Ayuki / Weekes, Samuel / Werner, Johannes / Westfall, David / Wieler, Lothar H / Williams, Michelle / Wolf, Silver A / Wong, Brian / Wong, Yan Ling / Wong, Tyler / Wright, Rasheena / Wunderlin, Tina / Yamanaka, Ryota / Yang, Jingcheng / Yano, Hirokazu / Yeh, George C / Yemets, Olena / Yeskova, Tetiana / Yoshikawa, Shusei / Zafar, Laraib / Zhang, Yang / Zhang, Shu / Zhang, Amy / Zheng, Yuanting / Zubenko, Stas

    Cell. 2021 June 24, v. 184, no. 13

    2021  

    Abstract: We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial ecosystem. This atlas provides an annotated, geospatial profile of ... ...

    Institution The International MetaSUB Consortium
    Abstract We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial ecosystem. This atlas provides an annotated, geospatial profile of microbial strains, functional characteristics, antimicrobial resistance (AMR) markers, and genetic elements, including 10,928 viruses, 1,302 bacteria, 2 archaea, and 838,532 CRISPR arrays not found in reference databases. We identified 4,246 known species of urban microorganisms and a consistent set of 31 species found in 97% of samples that were distinct from human commensal organisms. Profiles of AMR genes varied widely in type and density across cities. Cities showed distinct microbial taxonomic signatures that were driven by climate and geographic differences. These results constitute a high-resolution global metagenomic atlas that enables discovery of organisms and genes, highlights potential public health and forensic applications, and provides a culture-independent view of AMR burden in cities.
    Keywords Archaea ; antibiotic resistance ; climate ; forensic sciences ; humans ; metagenomics ; microbial ecology ; microbiome ; public health
    Language English
    Dates of publication 2021-0624
    Size p. 3376-3393.e17.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 187009-9
    ISSN 1097-4172 ; 0092-8674
    ISSN (online) 1097-4172
    ISSN 0092-8674
    DOI 10.1016/j.cell.2021.05.002
    Database NAL-Catalogue (AGRICOLA)

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