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  1. AU="Ruhe, Johannes"
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  1. Article ; Online: Immune Adsorption for the Treatment of Fatigue-Dominant Long-/Post-COVID Syndrome.

    Ruhe, Johannes / Giszas, Benjamin / Schlosser, Mandy / Reuken, Philipp A / Wolf, Gunter / Stallmach, Andreas

    Deutsches Arzteblatt international

    2023  Volume 120, Issue 29-30, Page(s) 499–500

    MeSH term(s) Humans ; Adsorption ; COVID-19 ; Fatigue/etiology ; Fatigue/therapy
    Language English
    Publishing date 2023-11-20
    Publishing country Germany
    Document type Letter
    ZDB-ID 2406159-1
    ISSN 1866-0452 ; 1866-0452
    ISSN (online) 1866-0452
    ISSN 1866-0452
    DOI 10.3238/arztebl.m2023.0073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Graft function and health status in renal transplant recipients hospitalized for COVID-19: a single center case series.

    Giszas, Benjamin / Ruhe, Johannes / Schlosser, Mandy / Reuken, Philipp Alexander / John-Kroegel, Ulrike / Stallmach, Andreas / Wolf, Gunter

    Journal of nephrology

    2022  Volume 36, Issue 3, Page(s) 613–615

    MeSH term(s) Humans ; Kidney Transplantation ; COVID-19 ; Kidney ; Immunosuppressive Agents ; Health Status
    Chemical Substances Immunosuppressive Agents
    Language English
    Publishing date 2022-09-05
    Publishing country Italy
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 1093991-x
    ISSN 1724-6059 ; 1120-3625 ; 1121-8428
    ISSN (online) 1724-6059
    ISSN 1120-3625 ; 1121-8428
    DOI 10.1007/s40620-022-01451-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: In-vivo-Untersuchungen der axonalen Degeneration im Tiermodell der Multiplen Sklerose

    Ruhe, Johannes / Hein, Katharina / Metz, Imke

    2017  

    Abstract: We established a new rat modell for in-vivo research of axonal degeneration in the experimental autoimmune encephalomyelitis (eae). The modell offers to observe the degeneration of single axons in the optic nerv by using fluorescence microscopy ... ...

    Title variant In-vivo research of axonal degeneration in an animal modell of multiple sclerosis
    Author's details vorgelegt von Johannes Ruhe
    Abstract We established a new rat modell for in-vivo research of axonal degeneration in the experimental autoimmune encephalomyelitis (eae). The modell offers to observe the degeneration of single axons in the optic nerv by using fluorescence microscopy....
    Language German
    Size 1 Online-Ressource, Illustrationen, Diagramme
    Publishing place Göttingen
    Document type Book ; Online
    Database Special collection on veterinary medicine and general parasitology

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  4. Article ; Online: IgM-MGUS and associated membranoproliferative glomerulonephritis during IVIG administration.

    Ruhe, Johannes / Gröne, Hermann-Josef / Schlosser, Mandy / Kroegel, Claus / Wolf, Gunter / Busch, Martin

    Annals of hematology

    2020  Volume 100, Issue 4, Page(s) 1087–1088

    MeSH term(s) Female ; Glomerulonephritis, Membranoproliferative/complications ; Glomerulonephritis, Membranoproliferative/etiology ; Glomerulonephritis, Membranoproliferative/immunology ; Humans ; Immunoglobulin M/blood ; Immunoglobulin kappa-Chains/blood ; Immunoglobulin lambda-Chains/blood ; Immunoglobulins, Intravenous/administration & dosage ; Immunoglobulins, Intravenous/adverse effects ; Middle Aged ; Monoclonal Gammopathy of Undetermined Significance/complications ; Monoclonal Gammopathy of Undetermined Significance/diagnostic imaging ; Monoclonal Gammopathy of Undetermined Significance/drug therapy ; Monoclonal Gammopathy of Undetermined Significance/physiopathology ; Proteinuria/blood ; Ultrasonography ; X-Rays
    Chemical Substances Immunoglobulin M ; Immunoglobulin kappa-Chains ; Immunoglobulin lambda-Chains ; Immunoglobulins, Intravenous
    Language English
    Publishing date 2020-05-04
    Publishing country Germany
    Document type Case Reports ; Letter
    ZDB-ID 1064950-5
    ISSN 1432-0584 ; 0939-5555 ; 0945-8077
    ISSN (online) 1432-0584
    ISSN 0939-5555 ; 0945-8077
    DOI 10.1007/s00277-020-04046-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Acquired thrombotic thrombocytopenic purpura after first vaccination dose of BNT162b2 mRNA COVID-19 vaccine.

    Ruhe, Johannes / Schnetzke, Ulf / Kentouche, Karim / Prims, Florian / Baier, Michael / Herfurth, Konstantin / Schlosser, Mandy / Busch, Martin / Hochhaus, Andreas / Wolf, Gunter

    Annals of hematology

    2021  Volume 101, Issue 3, Page(s) 717–719

    MeSH term(s) Aged, 80 and over ; BNT162 Vaccine/administration & dosage ; BNT162 Vaccine/adverse effects ; BNT162 Vaccine/immunology ; Biomarkers ; COVID-19/prevention & control ; Female ; Humans ; Platelet Count ; Purpura, Thrombotic Thrombocytopenic/diagnosis ; Purpura, Thrombotic Thrombocytopenic/etiology ; SARS-CoV-2/immunology ; Symptom Assessment ; Vaccination/adverse effects
    Chemical Substances Biomarkers ; BNT162 Vaccine (N38TVC63NU)
    Language English
    Publishing date 2021-07-26
    Publishing country Germany
    Document type Case Reports ; Letter
    ZDB-ID 1064950-5
    ISSN 1432-0584 ; 0939-5555 ; 0945-8077
    ISSN (online) 1432-0584
    ISSN 0939-5555 ; 0945-8077
    DOI 10.1007/s00277-021-04584-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Cardiovascular risk due to diabetes mellitus in patients with chronic kidney disease-prospective data from the German Chronic Kidney Disease cohort.

    Ruhe, Johannes / Nadal, Jennifer / Bärthlein, Barbara / Meiselbach, Heike / Schultheiss, Ulla T / Kotsis, Fruzsina / Stockmann, Helena / Krane, Vera / Sommerer, Claudia / Löffler, Ivonne / Saritas, Turgay / Kielstein, Jan T / Sitter, Thomas / Schneider, Markus P / Schmid, Matthias / Wanner, Christoph / Eckardt, Kai-Uwe / Wolf, Gunter / Busch, Martin

    Clinical kidney journal

    2023  Volume 16, Issue 11, Page(s) 2032–2040

    Abstract: Background: Diabetes mellitus (DM) and chronic kidney disease (CKD) are well-known cardiovascular and mortality risk factors. To what extent they act in an additive manner and whether the etiology of CKD modifies the risk is uncertain.: Methods: The ... ...

    Abstract Background: Diabetes mellitus (DM) and chronic kidney disease (CKD) are well-known cardiovascular and mortality risk factors. To what extent they act in an additive manner and whether the etiology of CKD modifies the risk is uncertain.
    Methods: The multicenter, prospective, observational German Chronic Kidney Disease study comprises 5217 participants (1868 with DM) with a baseline mean estimated glomerular filtration rate of 30-60 mL/min/1.73 m
    Results: During the 6.5-year follow-up 603 (12%) non-cardiovascular and 209 (4%) cardiovascular deaths, 645 (12%) 4-point MACE, and 398 (8%) HHF were observed, most frequently in patients with DM having CKDcvm. DM increased the risk of non-cardiovascular [hazard ratio (HR) 1.92; 95% confidence interval (CI) 1.59-2.32] and cardiovascular (HR 2.25; 95% CI 1.62-3.12) deaths, 4-point MACE (HR 1.93; 95% CI 1.62-2.31) and HHF (HR 1.87; 95% CI 1.48-2.36). Mortality risks were elevated by DM to a similar extent in CKDcvm and CKDgen, but for HHF in CKDcvm only (HR 2.07; 95% CI 1.55-2.77). In patients with DM, CKDcvm (versus CKDgen) only increased the risk for HHF (HR 1.93; 95% CI 1.15-3.22).
    Conclusions: DM contributes to cardiovascular and mortality excess risk in patients with moderate to severe CKD in both, CKDcvm and CKDgen. Patients with DM and CKDcvm are particularly susceptible to HHF.
    Language English
    Publishing date 2023-09-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfad194
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online ; Thesis: Charakteristika und Verlauf von asymptomatischen und symptomatischen Bakteriurien nach Nierentransplantation

    Ruhe, Johannes [Verfasser] / Busch, Martin [Gutachter] / Pfister, Wolfgang [Gutachter] / Girndt, Matthias [Gutachter]

    eine retrospektive monozentrische Studie

    2018  

    Author's details Johannes Ruhe ; Gutachter: Martin Busch, Wolfgang Pfister, Matthias Girndt
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Friedrich-Schiller-Universität Jena
    Publishing place Jena
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  8. Book ; Online ; Thesis: In-vivo-Untersuchungen der axonalen Degeneration im Tiermodell der Multiplen Sklerose

    Ruhe, Johannes [Verfasser] / Hein, Katharina [Akademischer Betreuer] / Hein, Katharina [Gutachter] / Metz, Imke [Gutachter]

    2017  

    Author's details Johannes Ruhe ; Gutachter: Katharina Hein, Imke Metz ; Betreuer: Katharina Hein
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Niedersächsische Staats- und Universitätsbibliothek Göttingen
    Publishing place Göttingen
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  9. Article: Acquired thrombotic thrombocytopenic purpura after first vaccination dose of BNT162b2 mRNA COVID-19 vaccine

    Ruhe, Johannes

    http://lobid.org/resources/99370678538206441#!, 101(3):717-719

    2021  

    Abstract: Since the survival rates of pediatric patients undergoing cancer treatment or hematopoietic stem cell transplantation (HSCT) have increased rapidly in recent decades, the late effects of treatment are now an important focus of patient care. Access to ... ...

    Abstract Since the survival rates of pediatric patients undergoing cancer treatment or hematopoietic stem cell transplantation (HSCT) have increased rapidly in recent decades, the late effects of treatment are now an important focus of patient care. Access to fertility preservation (FP) procedures as well as their financing differs considerably across Europe. However, some countries in Europe have recently changed the legal basis for financing FP procedures; therefore, the implementation of structures is mandatory to give patients access to FP. In this prospective cohort study, we characterized the process for establishing pediatric fertility counseling, including the development of an in-house standard procedure for recommendations regarding FP with potentially gonadotoxic treatment and valuating data from all FP counseling sessions. All data concerning patient characteristics (pubertal status, disease group) and recommendation of FP measures were prospectively collected and adoption of FP measures analyzed. Prior to the establishment of a structured process for FP in our pediatric oncology and stem cell transplantation center, there was no standardized FP counseling. We demonstrate that with the establishment of an inhouse standard procedure, it is possible to give consistent yet individualized FP counseling to approximately 90% of our patients facing gonadotoxic treatment, counseling over 200 patients between 2017 and 2019. This pilot study could potentially be adapted in other pediatric hematology, oncology, and stem cell transplantation centers to allow a more standardized handling of FP counseling for all patients facing gonadotoxic treatment.
    Keywords COVID-19 ; COVID-19/prevention ; Aged, 80 and over [MeSH] ; BNT162 Vaccine/adverse effects [MeSH] ; BNT162 Vaccine/administration ; BNT162 Vaccine/immunology [MeSH] ; Biomarkers [MeSH] ; Female [MeSH] ; Hematology ; Humans [MeSH] ; Oncology ; Letter to the Editor ; SARS-CoV-2/immunology [MeSH] ; Symptom Assessment [MeSH] ; Platelet Count [MeSH] ; Purpura, Thrombotic Thrombocytopenic/diagnosis [MeSH] ; Purpura, Thrombotic Thrombocytopenic/etiology [MeSH] ; Vaccination/adverse effects [MeSH]
    Language English
    Document type Article
    Database Repository for Life Sciences

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