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  1. Book: 2007 ESH ESC guidelines for the management of hypertension, from theory to practice

    Ruilope, Luis M.

    (Journal of hypertension ; 27, Suppl. 3)

    2009  

    Title variant Two thousand and seven ESH ESC guidelines for the management of hypertension, from theory to practice
    Institution European Society of Hypertension
    European Society of Cardiology
    Author's details ed.: Luis M. Ruilope
    Series title Journal of hypertension ; 27, Suppl. 3
    Collection
    Language English
    Size S32 S. : graph. Darst.
    Publisher Wolters Kluwer Health Lippincott Williams & Wilkins
    Publishing place Hagerstown, Md
    Publishing country United States
    Document type Book
    HBZ-ID HT016006549
    Database Catalogue ZB MED Medicine, Health

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    Zs A 1885 -27,Suppl.3- not available for loan Zeitschriften-Lesesaal

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  2. Article ; Online: Hypertension and the kidney: an update.

    Ruilope, Luis M / Ortiz, Alberto / Ruiz-Hurtado, Gema

    European heart journal

    2024  

    Language English
    Publishing date 2024-02-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehad896
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1563: Show issues Location:
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    Zs.MO 640: Show issues

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  3. Article ; Online: Renal denervation for the treatment of hypertension and kidney disease.

    Camafort, Miguel / Ihm, Sang Hyun / Ruilope, Luis Miguel

    Current opinion in nephrology and hypertension

    2023  Volume 32, Issue 6, Page(s) 544–550

    Abstract: Purpose of review: Hypertension is a condition characterized by increased sympathetic activity and the autonomic nervous system. Resistant hypertension, a condition with a prevalence of 10% to 20% in the general hypertensive population, is more likely ... ...

    Abstract Purpose of review: Hypertension is a condition characterized by increased sympathetic activity and the autonomic nervous system. Resistant hypertension, a condition with a prevalence of 10% to 20% in the general hypertensive population, is more likely to experience poor outcomes and adverse cardiovascular events. Renal sympathetic denervation (RDN), a minimally invasive, catheter-based percutaneous intervention, has been considered for treating this condition. Clinical trials have used various catheters, such as the Symplicity Spyral catheter, Vessix Renal Denervation system, and Paradise endovascular ultrasound renal denervation system.
    Recent findings: After the first randomized clinical trials examining the effectiveness and safety of RDN for lowering blood pressure in hypertensive patients, new clinical trials have used various catheters based on radiofrequency, such as the Spyral catheter, Vessix Renal Denervation system, or based on radiofrequency as the Paradise endovascular ultrasound renal denervation system. Positive results on this trials have shown that endovascular RDN (radiofrequency energy or high focused ultrasound energy) could be considered as a treatment option for uncontrolled resistant hypertension.
    Summary: Therefore, endovascular RDN (radiofrequency energy or high focused ultrasound energy) could be considered as a treatment option for uncontrolled resistant hypertension, which can be considered as an alternative to increasing medication. Nevertheless more data are needed, mainly in cardiovascular outcomes. RDN should be performed in experienced and specialized centers with a multidisciplinary team, and the benefits and risks of RDN should be addressed in a shared-decision-making process.
    Language English
    Publishing date 2023-09-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 1151092-4
    ISSN 1473-6543 ; 1535-3842 ; 1062-4813 ; 1062-4821
    ISSN (online) 1473-6543 ; 1535-3842
    ISSN 1062-4813 ; 1062-4821
    DOI 10.1097/MNH.0000000000000928
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3686: Show issues Location:
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  4. Article ; Online: Ambulatory blood pressure monitoring and mortality - Authors' reply.

    de la Sierra, Alejandro / Staplin, Natalie / Ruilope, Luis M / Baigent, Colin / Williams, Bryan

    Lancet (London, England)

    2024  Volume 403, Issue 10429, Page(s) 812

    MeSH term(s) Humans ; Blood Pressure Monitoring, Ambulatory ; Hypertension/diagnosis ; Blood Pressure Determination ; Blood Pressure/physiology
    Language English
    Publishing date 2024-02-18
    Publishing country England
    Document type Letter
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(23)02618-1
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    Zs.MG 94: Show issues

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  5. Article ; Online: Blood pressure control according to type 2 diabetes status.

    Ruilope, Luis M / Ruiz-Hurtado, Gema

    The lancet. Diabetes & endocrinology

    2022  Volume 10, Issue 9, Page(s) 612–613

    MeSH term(s) Blood Glucose ; Blood Pressure ; Diabetes Mellitus, Type 2 ; Humans ; Hypertension
    Chemical Substances Blood Glucose
    Language English
    Publishing date 2022-07-22
    Publishing country England
    Document type Journal Article ; Comment
    ISSN 2213-8595
    ISSN (online) 2213-8595
    DOI 10.1016/S2213-8587(22)00191-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Additional information regarding the SEVITENSION study.

    Ruilope, Luis

    Advances in therapy

    2014  Volume 31, Issue 8, Page(s) 777–779

    MeSH term(s) Amlodipine/administration & dosage ; Female ; Humans ; Hypertension/drug therapy ; Imidazoles/administration & dosage ; Male ; Perindopril/administration & dosage ; Tetrazoles/administration & dosage
    Chemical Substances Imidazoles ; Tetrazoles ; Amlodipine (1J444QC288) ; Perindopril (Y5GMK36KGY)
    Language English
    Publishing date 2014-08-22
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 632651-1
    ISSN 1865-8652 ; 0741-238X
    ISSN (online) 1865-8652
    ISSN 0741-238X
    DOI 10.1007/s12325-014-0144-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    Zs.A 2101: Show issues Location:
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  7. Article ; Online: Physical activity, chronic kidney disease, and cardiovascular risk: A study in half a million adults.

    Castillo-García, Adrián / Valenzuela, Pedro L / Saco-Ledo, Gonzalo / Morales, Javier S / Ruilope, Luis M / Santos-Lozano, Alejandro / Lucia, Alejandro

    Scandinavian journal of medicine & science in sports

    2024  Volume 34, Issue 1, Page(s) e14557

    Abstract: Objective: There is a growing prevalence of chronic kidney disease (CKD), a condition associated with a higher cardiovascular disease (CVD) risk. We assessed the association between self-reported physical activity (PA) and CKD and also studied whether ... ...

    Abstract Objective: There is a growing prevalence of chronic kidney disease (CKD), a condition associated with a higher cardiovascular disease (CVD) risk. We assessed the association between self-reported physical activity (PA) and CKD and also studied whether PA attenuates CKD-associated CVD risk.
    Methods: A cohort of Spanish adults (18-64 years) participated in this nationwide study. Participants were categorized at baseline as being either inactive (performing no PA), regularly, or insufficiently active (meeting or not, respectively, international PA recommendations) and were followed for up to 5 years. The presence of CKD (estimated glomerular filtration rate <60 mL/min/1.73 m
    Results: 517 917 participants (44 ± 9 years, 67% male, CKD prevalence = 7%) were studied at baseline, with prospective analyses (median follow-up = 2 years, range = 2-5) in a subcohort of 264 581 individuals. Compared to physical inactivity, cross-sectional analyses at baseline showed that regular PA (odds ratio = 0.80; 95% confidence interval = 0.79-0.81), but not insufficient PA (1.02; 0.99-1.04) was associated with lower CKD prevalence. However, prospective analyses failed to confirm this association (p > 0.1). In turn, CKD was associated with a higher prevalence of hypertension (+3%) and diabetes (+5%) at baseline and with a greater incidence of hypertension at follow-up (+37%). Among those participants with CKD, regular PA was associated with a lower prevalence (-45% to -7%) and incidence (-38% to -4%) of all CVD risk factors.
    Conclusion: Although PA might not reduce incident CKD in the middle term (~2 years), it can attenuate the CVD risk linked to this condition.
    MeSH term(s) Adult ; Humans ; Male ; Female ; Cardiovascular Diseases/epidemiology ; Cross-Sectional Studies ; Prospective Studies ; Risk Factors ; Heart Disease Risk Factors ; Exercise ; Hypertension/epidemiology ; Renal Insufficiency, Chronic/epidemiology ; Diabetes Mellitus
    Language English
    Publishing date 2024-01-24
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1077418-x
    ISSN 1600-0838 ; 0905-7188
    ISSN (online) 1600-0838
    ISSN 0905-7188
    DOI 10.1111/sms.14557
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    Zs.A 3247: Show issues Location:
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  8. Article ; Online: A blunted nocturnal blood pressure decline is associated with all-cause and cardiovascular mortality.

    de la Sierra, Alejandro / Staplin, Natalie / Ruilope, Luis M / Gorostidi, Manuel / Vinyoles, Ernest / Segura, Julián / Baigent, Colin / Williams, Bryan

    Journal of hypertension

    2024  

    Abstract: Objective: It has been suggested that a blunted nocturnal blood pressure (BP) decline is associated with a poor prognosis. Nevertheless, it remains unclear if an abnormal dipping is deleterious per se or it merely reflects an elevated BP during sleep. ... ...

    Abstract Objective: It has been suggested that a blunted nocturnal blood pressure (BP) decline is associated with a poor prognosis. Nevertheless, it remains unclear if an abnormal dipping is deleterious per se or it merely reflects an elevated BP during sleep. We aimed to assess the prognostic value of nocturnal BP decline, with or without concomitant elevated nocturnal BP.
    Methods: Vital status and cause of death were obtained from death certificates in 59 124 patients, enrolled in the Spanish ABPM Registry between 2004 and 2014 (median follow-up: 10 years). The association between night-to-day ratio (NDR) and dipping patterns (extreme dippers, dippers, reduced dippers, and risers) with all-cause and cardiovascular mortality were evaluated by Cox-proportional models adjusted for clinical confounders and 24 h blood pressure.
    Results: NDR was associated with all-cause mortality [hazard ratio for 1SD change: 1.15; 95% confidence interval (CI) 1.13-1.17]. Reduced dippers (1.13; 1.06-1.20) and risers (1.41; 1.32-1.51) were associated with an increased risk of all-cause death, whereas extreme dippers (0.90; 0.79-1.02) were not. Elevated NDR (≥0.9) in the absence of elevated night SBP (<120 mmHg) was associated with an increased risk of death (1.13; 1.04-1.22), as well as elevated night SBP but normal NDR (1.38; 1.26-1.50), and the combination of both abnormalities (1.56; 1.46-1.66). Similar results were obtained for cardiovascular mortality.
    Conclusion: Abnormalities in the circadian pattern are associated with an increased risk of all-cause and cardiovascular mortality. This is maintained even in the absence of nocturnal BP elevation.
    Language English
    Publishing date 2024-03-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 605532-1
    ISSN 1473-5598 ; 0263-6352 ; 0952-1178
    ISSN (online) 1473-5598
    ISSN 0263-6352 ; 0952-1178
    DOI 10.1097/HJH.0000000000003712
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 614: Show issues

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  9. Article ; Online: Lifestyle and cardiovascular risk in working young adults: insights from a nationwide Spanish cohort.

    Castillo-García, Adrián / Valenzuela, Pedro L / Saco-Ledo, Gonzalo / Carrera-Bastos, Pedro / Ruilope, Luis M / Santos-Lozano, Alejandro / Lucia, Alejandro

    Revista espanola de cardiologia (English ed.)

    2024  

    Abstract: Introduction and objectives: This study aimed to describe the cardiovascular risk profile of working young adults from Spain and its association with lifestyle.: Methods: Participants (18-30 years) were recruited from a nationwide cohort of ... ...

    Abstract Introduction and objectives: This study aimed to describe the cardiovascular risk profile of working young adults from Spain and its association with lifestyle.
    Methods: Participants (18-30 years) were recruited from a nationwide cohort of economically active adults insured by a large occupational risk prevention company, with data obtained from routine medical assessments. The participants were categorized as having an "unhealthy" cardiovascular risk profile based on the presence of prediabetes/diabetes, prehypertension/hypertension, or hypercholesterolemia, or a "healthy" profile if these conditions were completely absent. The association with lifestyle factors (weight, physical activity, sleeping characteristics, alcohol consumption, smoking) was assessed.
    Results: A total of 78 421 young adults (27±2 years, 36% female) were evaluated at baseline. The "unhealthy" cardiovascular risk profile was prevalent (18%) and inversely associated (OR, 0.64; 95%CI, 0.57-0.80) with an optimal lifestyle (normal weight, regular physical activity, no drinking/smoking, and good sleep). The latter condition was found in only 3.5% of the participants. On the other hand, prospective analyses in 44 776 participants (median follow-up=2 [range 2-5] years) showed that 2.0% transitioned from a "healthy" to an "unhealthy" profile. Being physically active (OR, 0.95; 95%CI, 0.81-0.99) and having a normal weight (OR, 0.61; 95%CI, 0.51-0.70) were associated with a lower likelihood of this transition. No consistent associations were found for other lifestyle factors.
    Conclusions: The prevalence of cardiovascular risk factors is high in economically active young Spanish adults. An unhealthy cardiovascular risk profile is inversely associated with an optimal lifestyle, but the latter is highly infrequent in this population.
    Language Spanish
    Publishing date 2024-02-27
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 2592481-3
    ISSN 1885-5857 ; 1885-5857
    ISSN (online) 1885-5857
    ISSN 1885-5857
    DOI 10.1016/j.rec.2024.02.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Physical Exercise in Resistant Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    Saco-Ledo, Gonzalo / Valenzuela, Pedro L / Ruilope, Luis M / Lucia, Alejandro

    Frontiers in cardiovascular medicine

    2022  Volume 9, Page(s) 893811

    Abstract: Physical exercise reduces blood pressure (BP) in patients with hypertension in general but more evidence is needed specifically for a high-risk phenotype associated with intensive medication, resistant hypertension (RH). In this systematic review and ... ...

    Abstract Physical exercise reduces blood pressure (BP) in patients with hypertension in general but more evidence is needed specifically for a high-risk phenotype associated with intensive medication, resistant hypertension (RH). In this systematic review and meta-analysis, we aimed to summarize current evidence of the exercise effects on BP in patients with RH. A systematic search was conducted in PubMed, Web of Science and Cochrane Library (from inception to 3rd November, 2021). A random effects meta-analysis was performed when at least two trials assessed the effect of either acute or regular exercise (vs. a control condition) on the same outcome. Ten studies (
    Language English
    Publishing date 2022-05-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2022.893811
    Database MEDical Literature Analysis and Retrieval System OnLINE

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