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  1. Article ; Online: Psychosis Treatment During COVID-19 Pandemic and the Potential Role of Phenothiazines: A Call for Research Studies.

    Ruiz de Pellón Santamaría, Ángel

    Journal of clinical psychopharmacology

    2020  Volume 40, Issue 6, Page(s) 641–642

    MeSH term(s) Antipsychotic Agents/pharmacokinetics ; Antipsychotic Agents/therapeutic use ; Betacoronavirus/drug effects ; Betacoronavirus/physiology ; Biological Availability ; Biomedical Research ; COVID-19 ; Chlorpromazine/pharmacokinetics ; Chlorpromazine/therapeutic use ; Coronavirus Infections/drug therapy ; Coronavirus Infections/metabolism ; Drug Repositioning/methods ; Humans ; Lung/drug effects ; Lung/metabolism ; Maximum Allowable Concentration ; Needs Assessment ; Pandemics ; Phenothiazines/pharmacokinetics ; Phenothiazines/therapeutic use ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/metabolism ; Psychotic Disorders/drug therapy ; SARS-CoV-2 ; Tissue Distribution
    Chemical Substances Antipsychotic Agents ; Phenothiazines ; Chlorpromazine (U42B7VYA4P)
    Keywords covid19
    Language English
    Publishing date 2020-11-01
    Publishing country United States
    Document type Letter
    ZDB-ID 604631-9
    ISSN 1533-712X ; 0271-0749
    ISSN (online) 1533-712X
    ISSN 0271-0749
    DOI 10.1097/JCP.0000000000001310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1664: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Psychosis Treatment During COVID-19 Pandemic and the Potential Role of Phenothiazines ; A Call for Research Studies

    Ruiz de Pellón Santamaría, Ángel

    Journal of Clinical Psychopharmacology

    2020  Volume 40, Issue 6, Page(s) 641–642

    Keywords Pharmacology (medical) ; Psychiatry and Mental health ; covid19
    Language English
    Publisher Ovid Technologies (Wolters Kluwer Health)
    Publishing country us
    Document type Article ; Online
    ZDB-ID 604631-9
    ISSN 1533-712X ; 0271-0749
    ISSN (online) 1533-712X
    ISSN 0271-0749
    DOI 10.1097/jcp.0000000000001310
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1664: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: An overall protective effect of antipsychotic drugs against COVID-19 seems implausible.

    Ruiz de Pellón-Santamaría, Ángel / Sarasqueta-Eizaguirre, Cristina / Basterrechea-Peña, Francisco Javier

    Schizophrenia research

    2021  Volume 243, Page(s) 486–488

    MeSH term(s) Antipsychotic Agents/therapeutic use ; Bipolar Disorder/drug therapy ; COVID-19 ; Delayed-Action Preparations/therapeutic use ; Humans ; Schizophrenia/drug therapy
    Chemical Substances Antipsychotic Agents ; Delayed-Action Preparations
    Language English
    Publishing date 2021-12-22
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 639422-x
    ISSN 1573-2509 ; 0920-9964
    ISSN (online) 1573-2509
    ISSN 0920-9964
    DOI 10.1016/j.schres.2021.12.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 543: Show issues

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  5. Article: Catatonia in older adults: A systematic review.

    Jaimes-Albornoz, Walter / Ruiz de Pellon-Santamaria, Angel / Nizama-Vía, Ayar / Isetta, Marco / Albajar, Ines / Serra-Mestres, Jordi

    World journal of psychiatry

    2022  Volume 12, Issue 2, Page(s) 348–367

    Abstract: Background: Catatonia is a complex psychomotor syndrome that often goes unrecognized and untreated, even though its classification has evolved in recent years. Prompt and correct identification of catatonia allows for highly effective treatment and ... ...

    Abstract Background: Catatonia is a complex psychomotor syndrome that often goes unrecognized and untreated, even though its classification has evolved in recent years. Prompt and correct identification of catatonia allows for highly effective treatment and prevention of possible complications. The underrecognition of catatonia in older patients is also frequent, and research in this population is scarce.
    Aim: To conduct a systematic review of the literature on catatonia in older people to ascertain its clinical characteristics across settings.
    Methods: Following the PRISMA guidelines, MEDLINE, EMBASE, and PsycINFO databases were searched from inception to December 2021, with a strategy aimed at identifying all articles published on catatonia in older adults. Titles and abstracts were scanned and selected independently by two authors. Papers investigating issues related to catatonia and/or catatonic symptoms in older people, with English abstracts available, were included. References of selected articles were revised to identify other relevant studies.
    Results: In total, 1355 articles were retrieved. After removing duplicates, 879 remained. Of the 879 identified abstracts, 669 were excluded because they did not meet the inclusion criteria. A total of 210 articles underwent full text review, and 51 were eliminated for various reasons. Fourteen more articles were selected from the references. Overall, 173 articles were reviewed: 108 case reports, 35 case series, 11 prospective cohort studies, 6 case-control studies, 3 retrospective cohort studies and 10 reviews. We found several particular aspects of catatonia in this population. Catatonia in older patients is highly prevalent and tends to have a multifactorial etiology. Older patients, compared to younger patients, have a higher risk of developing catatonia with benzodiazepine (BZD) withdrawal, in bipolar disorder, and in the general hospital. Age, together with other risk factors, was significantly associated with the incidence of deep venous thrombosis, neuroleptic malignant syndrome poor outcome, other complications and mortality. Treatment with BZDs and electroconvulsive therapy is safe and effective. Prompt treatment of its cause is essential to ensure a good prognosis.
    Conclusion: Catatonia in older patients is highly prevalent and tends to have a multifactorial etiology. The risk of developing catatonia in some settings and conditions, as well as of developing complications, is high in this population. Symptomatic treatment is safe and effective, and timely etiologic treatment is fundamental.
    Language English
    Publishing date 2022-02-19
    Publishing country United States
    Document type Journal Article
    ISSN 2220-3206
    ISSN 2220-3206
    DOI 10.5498/wjp.v12.i2.348
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Antihistamine and cationic amphiphilic drugs, old molecules as new tools against the COVID-19?

    Gitahy Falcao Faria, Clara / Weiner, Luisa / Petrignet, Julien / Hingray, Coraline / Ruiz De Pellon Santamaria, Ángel / Villoutreix, Bruno O / Beaune, Philippe / Leboyer, Marion / Javelot, Hervé

    Medical hypotheses

    2021  Volume 148, Page(s) 110508

    Abstract: Several studies have reported that certain psychoactive drugs could have a protective effect against SARS-CoV-2. Herein, we propose that antihistamines (anti-H1) and cationic amphiphilic drugs (CAD), specifically, have the capacity to disrupt virus entry ...

    Abstract Several studies have reported that certain psychoactive drugs could have a protective effect against SARS-CoV-2. Herein, we propose that antihistamines (anti-H1) and cationic amphiphilic drugs (CAD), specifically, have the capacity to disrupt virus entry and replication. In addition, several of these molecules have limited side effects and as such could be promising prophylactic candidates against SARS-CoV-2 infection.
    MeSH term(s) COVID-19/drug therapy ; COVID-19/virology ; Drug Repositioning ; Histamine H1 Antagonists/pharmacology ; Humans ; Models, Biological ; Pandemics ; SARS-CoV-2/drug effects ; SARS-CoV-2/physiology ; Surface-Active Agents/pharmacology ; Virus Internalization/drug effects ; Virus Replication/drug effects
    Chemical Substances Histamine H1 Antagonists ; Surface-Active Agents
    Language English
    Publishing date 2021-01-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2021.110508
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1132: Show issues Location:
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