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Article ; Online: Catheter Ablation for Atrial Fibrillation-Influence of Modifiable Risk Factors and Ablation Modality on Procedural Efficacy and Safety.

Sargent, Stephanie R / Mladenovic, Jordanna R / Liaw, Jacqueline J T / Siller, Jonathan / Russell, Penni L / Tung, Matthew K Y / Holland, David J

Heart, lung & circulation

2024  

Abstract: Background: Modifiable lifestyle risk factors, in particular obesity and related conditions, are important drivers of atrial fibrillation (AF), impacting the severity of symptoms and influence the efficacy and safety of treatment.: Objective: The ... ...

Abstract Background: Modifiable lifestyle risk factors, in particular obesity and related conditions, are important drivers of atrial fibrillation (AF), impacting the severity of symptoms and influence the efficacy and safety of treatment.
Objective: The study aimed to assess the impact of modifiable lifestyle factors on the effectiveness and safety of AF ablation, and examine the procedural characteristics, efficacy, safety and cost outcomes of cryoballoon vs radiofrequency ablation, in a real-world clinical setting.
Method: Patients undergoing catheter ablation for AF (June 2017 to December 2020) were included in this retrospective analysis. Efficacy and safety outcomes were obtained from electronic medical records and state-wide databases. The primary outcome was successful isolation of the pulmonary veins and freedom from AF without repeat ablation or ongoing antiarrhythmic therapy at 12 months.
Results: The study included 141 patients (mean age 60±11 years, 57% male). The average body mass index (BMI) was 29.2±5.6 kg/m
Conclusions: Catheter ablation for AF is more likely to be unsuccessful in patients with uncontrolled risk factors, particularly obesity. Risk factor optimisation may improve procedural success and reduce the risk of procedural complications.
Language English
Publishing date 2024-04-02
Publishing country Australia
Document type Journal Article
ZDB-ID 2020980-0
ISSN 1444-2892 ; 1443-9506
ISSN (online) 1444-2892
ISSN 1443-9506
DOI 10.1016/j.hlc.2024.02.009
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