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Artikel ; Online: Reply.

Hariri, Nizari / Russell, Todd / Kasper, Gregory / Lurie, Fedor

2019 Band 70, Heft 5, Seite(n) 1724–1725

Mesh-Begriff(e)	Carotid Stenosis ; Humans
Sprache	Englisch
Erscheinungsdatum	2019-10-25
Erscheinungsland	United States
Dokumenttyp	Letter ; Comment
ZDB-ID	605700-7
ISSN	1097-6809 ; 0741-5214
ISSN (online)	1097-6809
ISSN	0741-5214
DOI	10.1016/j.jvs.2019.06.180
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: The clinical significance of ultra-high D-dimer levels.

Schafer, Kristin / Goldschmidt, Eric / Oostra, Drew / Fish, John / Russell, Todd / Lurie, Fedor

Journal of vascular surgery. Venous and lymphatic disorders

2021 Band 10, Heft 1, Seite(n) 8–13

Abstract: Objective: Plasma D-dimer levels >5000 ng/mL are encountered in a number of conditions other than venous thromboembolism (VTE). Recent studies have used plasma D-dimer levels as a prognostic indicator for coronavirus disease 2019 (COVID-19) infection. ... ...

Abstract	Objective: Plasma D-dimer levels >5000 ng/mL are encountered in a number of conditions other than venous thromboembolism (VTE). Recent studies have used plasma D-dimer levels as a prognostic indicator for coronavirus disease 2019 (COVID-19) infection. The implications of abnormal levels are less clear for patients diagnosed with COVID-19 with a baseline elevation in plasma D-dimer levels. In the present study, we reviewed the occurrence of plasma D-dimer levels >5000 ng/mL and investigated the clinical significance of this finding before the onset of the COVID-19 pandemic. Methods: Inpatient records for a 4-year period were screened for laboratory results of plasma D-dimer levels >5000 ng/mL. The patient data were reviewed for the clinical identifiers commonly associated with elevated plasma D-dimer levels, including VTE, cancer, sepsis, pneumonia, other infection, bleeding, and trauma. The patients were then categorized into groups stratified by the plasma D-dimer level to allow for comparisons between the various clinical diagnoses. Results: A total of 671 patients were included in the present study. VTE was the most common diagnosis for patients with a plasma D-dimer level >5000 ng/mL, followed by cancer and pneumonia. Multiple clinical diagnoses were present in 61% of the patients. No clear cause for the ultra-high plasma D-dimer level could be identified in 11.3% of the patients. Among the patients lacking a clinical diagnosis at discharge, mortality was 24% in the 5000- to 10,000-ng/mL group, 28.6% in the 10,000- to 15,000-ng/mL group, and 75% in the >15,000-ng/mL group. Conclusions: VTE, cancer, and pneumonia were frequently present when ultra-high plasma D-dimer levels were encountered, and mortality was high when the levels were >15,000 ng/mL. The results from our study from a pre-COVID-19 patient population suggest that ultra-high plasma D-dimer levels indicate the presence of severe underlying disease. This should be considered when using the plasma D-dimer level as a screening tool or prognostic indicator for COVID-19 infection.
Mesh-Begriff(e)	Aged ; Biomarkers/blood ; COVID-19/blood ; COVID-19/complications ; COVID-19/epidemiology ; Cross-Sectional Studies ; Female ; Fibrin Fibrinogen Degradation Products/metabolism ; Follow-Up Studies ; Humans ; Male ; Ohio/epidemiology ; Pandemics ; Retrospective Studies ; Time Factors ; Venous Thromboembolism/blood ; Venous Thromboembolism/etiology
Chemische Substanzen	Biomarkers ; Fibrin Fibrinogen Degradation Products ; fibrin fragment D
Sprache	Englisch
Erscheinungsdatum	2021-06-23
Erscheinungsland	United States
Dokumenttyp	Journal Article ; Multicenter Study ; Observational Study
ISSN	2213-3348
ISSN (online)	2213-3348
DOI	10.1016/j.jvsv.2021.06.011
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Shear rate is a better marker of symptomatic ischemic cerebrovascular events than velocity or diameter in severe carotid artery stenosis.

Hariri, Nizar / Russell, Todd / Kasper, Gregory / Lurie, Fedor

Journal of vascular surgery

2018 Band 69, Heft 2, Seite(n) 448–452

Abstract: Objective: This study was designed to test the hypothesis that the high shear rate of flow in the area of carotid stenosis is associated with the incidence of ischemic symptoms in patients with a high degree of carotid stenosis.: Methods: This is a ... ...

Abstract	Objective: This study was designed to test the hypothesis that the high shear rate of flow in the area of carotid stenosis is associated with the incidence of ischemic symptoms in patients with a high degree of carotid stenosis. Methods: This is a case-control study of patients with >70% stenosis of the internal carotid artery (ICA) identified by duplex ultrasound in an Intersocietal Accreditation Commission-accredited laboratory during 1 year. Symptomatic patients were included in the study group, and asymptomatic patients served as controls. Shear rates were calculated from high-resolution ultrasound images. Descriptive statistics and univariate and multivariate analysis were performed to account for confounding factors. Receiver operating characteristic curves were used to compare diagnostic values of shear rate, velocities, and diameters of the ICA. Results: The study included 308 patients (55.5% male; mean age, 73 ± 10 years); 209 of them were asymptomatic and 99 were symptomatic. The mean shear rate was 7930 s Conclusions: In patients with >70% ICA stenosis, the shear rate is associated with the prevalence of symptomatic cerebrovascular ischemic events. A shear rate of 8000 s
Mesh-Begriff(e)	Aged ; Aged, 80 and over ; Blood Flow Velocity ; Brain Ischemia/diagnostic imaging ; Brain Ischemia/epidemiology ; Brain Ischemia/physiopathology ; Carotid Artery, Internal/diagnostic imaging ; Carotid Artery, Internal/physiopathology ; Carotid Stenosis/diagnostic imaging ; Carotid Stenosis/epidemiology ; Carotid Stenosis/physiopathology ; Case-Control Studies ; Female ; Hemodynamics ; Humans ; Incidence ; Male ; Middle Aged ; Prevalence ; Prognosis ; Regional Blood Flow ; Risk Assessment ; Risk Factors ; Severity of Illness Index ; Stress, Mechanical ; Ultrasonography, Doppler, Duplex
Sprache	Englisch
Erscheinungsdatum	2018-06-22
Erscheinungsland	United States
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	605700-7
ISSN	1097-6809 ; 0741-5214
ISSN (online)	1097-6809
ISSN	0741-5214
DOI	10.1016/j.jvs.2018.04.036
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Risk and Representation in Research Ethics: The NunatuKavut Experience.

Brunger, Fern / Russell, Todd

Journal of empirical research on human research ethics : JERHRE

2015 Band 10, Heft 4, Seite(n) 368–379

Abstract: This article examines Canadian policy governing the ethics of research involving Indigenous communities. Academics and community members collaborated in research to examine how best to apply the Tri-Council Policy Statement guidelines in a community with ...

Abstract	This article examines Canadian policy governing the ethics of research involving Indigenous communities. Academics and community members collaborated in research to examine how best to apply the Tri-Council Policy Statement guidelines in a community with complex and multiple political and cultural jurisdictions. We examined issues of NunatuKavut (Southern Inuit) authority and representation in relation to governance of research in a context where community identity is complex and shifting, and new provincial legislation mandates centralized ethics review. We describe the politics of risk--the ways in which collective identity and research risks are co-constructed. Our case study illustrates that collective consent to research must emphasize shifting identity construction in relation to the particular risks and benefits invoked by the research question, to ascertain with which groups or individuals the negotiation of risk should take place in the first place. We conclude by describing a necessary re-imagining of policy governing research ethics involving Indigenous communities.
Mesh-Begriff(e)	Canada ; Culture ; Ethics, Research ; Humans ; Informed Consent ; Inuits ; Policy ; Politics ; Residence Characteristics ; Risk
Sprache	Englisch
Erscheinungsdatum	2015-10
Erscheinungsland	United States
Dokumenttyp	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2263068-5
ISSN	1556-2654 ; 1556-2646
ISSN (online)	1556-2654
ISSN	1556-2646
DOI	10.1177/1556264615599687
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Interface pressure changes under compression bandages during period of wearing.

Ning, Junjie / Ma, Wudi / Fish, John / Abbas, Jihad / Seiwert, Andrew / Russell, Todd / Lurie, Fedor

Journal of vascular surgery. Venous and lymphatic disorders

2020 Band 9, Heft 4, Seite(n) 971–976

Abstract: Background: The aim of the present study was to investigate the changes in pressure over time under three different compression bandages and compare the temporal patterns of pressure changes among them.: Methods: The 4-hour changes in interface ... ...

Abstract	Background: The aim of the present study was to investigate the changes in pressure over time under three different compression bandages and compare the temporal patterns of pressure changes among them. Methods: The 4-hour changes in interface pressure were investigated in 10 volunteers with no venous disease or leg swelling. In 20 patients with venous ulcers, the change in interface pressure was measured after 4 hours, 1 day, and 7 days of bandage wearing. The three bandages tested were the Smart Sleeve compression system (SSB; Carolon, Rural Hall, NC), Coban 2 (C2; 3M, St Paul, Minn), and Profore Lite (PL; Smith & Nephew, London, United Kingdom). Pressure measurements were performed using the PicoPress transducer (Microlab, Padua, Italy) and the Juzo Pressure Monitor (Juzo, Cuyahoga Falls, Ohio). Results: In the 10 volunteers, the mean pressure loss during the first 4 hours under the SSB, C2, and PL were 4.5, 3.7, and 6.6 mm Hg, respectively. No significant differences were seen in the pressure loss among the three bandages, whether in the supine (P = .59) or standing (P = .47) position. In the 20 patients with venous ulcers, the pressure had decreased gradually over 7 days under the C2 bandages. For the SSB and PL bandages, however, the interface pressure was relatively stable during the first day but decreased significantly afterward. The mean pressure loss during the 7 days was 4.7, 7.7, and 8.6 mm Hg for the SSB, PL, and C2, respectively (P = .017). Only the SSB maintained a desirable mean pressure >30.0 mm Hg on the seventh day in the patients with venous ulcers. Conclusions: The interface pressure had decreased over time under all three studied bandages. However, the temporal pattern of the pressure changes varied among the different bandages. Therefore, monitoring the interface pressure, allowing for adjustment or changes of the bandage at an accurate point, is essential to maintain a desirable interface pressure during compression therapy.
Mesh-Begriff(e)	Compression Bandages ; Equipment Design ; Humans ; Pressure ; Prospective Studies ; Time Factors ; Varicose Ulcer/physiopathology ; Varicose Ulcer/therapy
Sprache	Englisch
Erscheinungsdatum	2020-11-11
Erscheinungsland	United States
Dokumenttyp	Comparative Study ; Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ISSN	2213-3348
ISSN (online)	2213-3348
DOI	10.1016/j.jvsv.2020.11.007
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Timing of Hospital-acquired Venous Thromboembolism and Its Relationship with Venous Thromboembolism Prevention Measures in Immobile Patients.

Pham, Hao / Russell, Todd / Seiwert, Andrew / Kasper, Gregory / Lurie, Fedor

Annals of vascular surgery

2018 Band 56, Seite(n) 24–28

Abstract: Background: The aim of this study is to describe the timing of venous thromboembolism (VTE) diagnosis in patients with cerebral or spinal trauma and stroke and describe the relationships between VTE prophylaxis and timing of VTE diagnosis at a community ...

Abstract	Background: The aim of this study is to describe the timing of venous thromboembolism (VTE) diagnosis in patients with cerebral or spinal trauma and stroke and describe the relationships between VTE prophylaxis and timing of VTE diagnosis at a community hospital. Methods: Retrospective cohort observational study over a span of 10 years from 2006 to 2016 was conducted. Results: Lower extremity ultrasound surveillance identified 138 patients who developed VTE during their hospital stay (mean age 62 years, 61.6% males). Mechanical prophylaxis was used in 79.7% and pharmacologic prophylaxis in 78.3% of patients. The average time of admission to administration of mechanical prophylaxis was 1.92 and 7.7 days for pharmacologic prophylaxis. In patients who received pharmacologic prophylaxis within 2 days, 51.5% of all VTE events occurred during the first week, 73.5% by the second week, and 91.2% by the third week of the hospital stay. In patients who started pharmacologic prophylaxis after 2 days in the hospital, 85% of all VTE events occurred within the first week and 90% within 10 days of the hospital stay (P < 0.001). The timing of initiation of mechanical prophylaxis did not influence the timing of VTE events. Conclusions: In immobilized patients with stroke, traumatic brain injury, or spinal cord injury, VTE screening should be performed at different schedules based on the timing of initiation of pharmacologic prophylaxis. In patients who did not start prophylaxis during the first 2 days of admission to the hospital, the majority of the VTE events occurred during the first 10 days.
Mesh-Begriff(e)	Adult ; Aged ; Aged, 80 and over ; Bed Rest/adverse effects ; Brain Injuries/complications ; Brain Injuries/diagnosis ; Brain Injuries/therapy ; Female ; Hospitals, Community ; Humans ; Male ; Middle Aged ; Patient Admission ; Retrospective Studies ; Risk Factors ; Spinal Injuries/complications ; Spinal Injuries/diagnosis ; Spinal Injuries/therapy ; Stroke/complications ; Stroke/diagnosis ; Stroke/therapy ; Time Factors ; Time-to-Treatment ; Treatment Outcome ; Ultrasonography ; Venous Thromboembolism/diagnostic imaging ; Venous Thromboembolism/etiology ; Venous Thromboembolism/prevention & control ; Young Adult
Sprache	Englisch
Erscheinungsdatum	2018-11-27
Erscheinungsland	Netherlands
Dokumenttyp	Journal Article ; Observational Study
ZDB-ID	1027366-9
ISSN	1615-5947 ; 0890-5096
ISSN (online)	1615-5947
ISSN	0890-5096
DOI	10.1016/j.avsg.2018.09.014
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: The Effect of Patient Oral Intake Status on Abdominal Aortic Ultrasound Visualization.

Goldschmidt, Eric / Al-Embideen, Somya / Abbas, Jihad / Russell, Todd / Paolini, David / Al-Balbissi, Laith / Lurie, Fedor

Annals of vascular surgery

2021 Band 74, Seite(n) 204–208

Abstract: Background: The standard abdominal aortic duplex ultrasound protocol requires fasting for 8-12 hours prior to examination in attempt to reduce bowel gas and improve visualization. Such practice results in frequent testing delays and patient non- ... ...

Abstract	Background: The standard abdominal aortic duplex ultrasound protocol requires fasting for 8-12 hours prior to examination in attempt to reduce bowel gas and improve visualization. Such practice results in frequent testing delays and patient non-compliance. The aim of this study was to determine whether fasting improves visualization of the abdominal aorta in patients undergoing duplex ultrasound or influences diagnostic properties. Methods: This was a prospective, randomized, double-blind imaging trail at a single institution. Ninety patients were randomized to one of three dietary groups, including NPO, clear liquids or control (regular diet). Diagnostic ultrasound examinations were performed by accredited Registered Vascular Technologists who remained blinded to the patients' diet. Sonographers commented on the presence of limited visualization in the study based on their ability to accurately measure aortic diameter. Examination results were randomly assigned to interpreting physicians who were also blinded to the patients' diet. Following interpretation, the reading physician was asked to comment whether they had sufficient information for a conclusive diagnostic interpretation. Results: All ultrasound studies were deemed diagnostic by the interpreting physician regardless of the patients' dietary status. Limited visualization was reported in 19 of the 90 study patients (21.1%) with no significant difference existing between the dietary groups (P = 0.344). The NPO group contained the most patients with studies deemed to have limited visualization. Conclusion: Oral intake status did not affect visualization of the abdominal aorta or the rate of diagnostic studies in patients undergoing DUS at a single center. These results suggest that dietary restrictions prior to DUS evaluation of the abdominal aorta is unnecessary.
Mesh-Begriff(e)	Aged ; Aged, 80 and over ; Aortic Aneurysm, Abdominal/diagnostic imaging ; Diet/adverse effects ; Double-Blind Method ; Drinking ; Eating ; Fasting ; Humans ; Middle Aged ; Ohio ; Pilot Projects ; Predictive Value of Tests ; Prospective Studies ; Reproducibility of Results ; Ultrasonography, Doppler, Duplex
Sprache	Englisch
Erscheinungsdatum	2021-02-05
Erscheinungsland	Netherlands
Dokumenttyp	Comparative Study ; Journal Article ; Randomized Controlled Trial
ZDB-ID	1027366-9
ISSN	1615-5947 ; 0890-5096
ISSN (online)	1615-5947
ISSN	0890-5096
DOI	10.1016/j.avsg.2020.12.035
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Decay of sewage-sourced microbial source tracking markers and fecal indicator bacteria in marine waters.

Mattioli, Mia Catharine / Sassoubre, Lauren M / Russell, Todd L / Boehm, Alexandria B

Water research

2017 Band 108, Seite(n) 106–114

Abstract: The decay of sewage-sourced enterococci, Escherichia coli, three human-associated microbial source tracking (MST) markers, Salmonella, Campylobacter, and norovirus GII was measured in situ in coastal, marine waters. Experiments examined the effects of ... ...

Abstract	The decay of sewage-sourced enterococci, Escherichia coli, three human-associated microbial source tracking (MST) markers, Salmonella, Campylobacter, and norovirus GII was measured in situ in coastal, marine waters. Experiments examined the effects of sunlight intensity and season on decay. Seawater was seeded with untreated sewage, placed into permeable dialysis bags, and deployed in the coastal ocean near the water surface, and at 18 cm, and 99 cm depths, to vary solar intensity, during winter and summer seasons. Microbial decay was modeled using a log-linear or shoulder log-linear decay model. Pathogen levels were too low in sewage to obtain kinetic parameters. Human-associated MST markers all decayed with approximately the same rate constant (k ∼ 1.5 d
Mesh-Begriff(e)	Bacteria ; Environmental Monitoring ; Escherichia coli ; Feces/microbiology ; Humans ; Renal Dialysis ; Sewage/microbiology ; Water Microbiology
Chemische Substanzen	Sewage
Sprache	Englisch
Erscheinungsdatum	2017-01-01
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	202613-2
ISSN	1879-2448 ; 0043-1354
ISSN (online)	1879-2448
ISSN	0043-1354
DOI	10.1016/j.watres.2016.10.066
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Cilostazol May Improve Maturation Rates and Durability of Vascular Access for Hemodialysis.

Russell, Todd E / Kasper, Gregory C / Seiwert, Andrew J / Comerota, Anthony J / Lurie, Fedor

Vascular and endovascular surgery

2017 Band 51, Heft 3, Seite(n) 120–124

Abstract: Cilostazol is effective in controlling pathophysiological pathways similar or identical to those involved in nonmaturation and failure of the arteriovenous access. This case-control study examined whether cilostazol would improve maturation rates and ... ...

Abstract	Cilostazol is effective in controlling pathophysiological pathways similar or identical to those involved in nonmaturation and failure of the arteriovenous access. This case-control study examined whether cilostazol would improve maturation rates and durability of vascular access for hemodialysis. The treatment group included 33 patients who received cilostazol for ≥30 days prior to creation of a dialysis access and continued with cilostazol therapy for ≥60 days after surgery. The matched (gender, age, race, diabetes, and the year of surgery) control group included 116 patients who underwent the same procedure but did not receive cilostazol prior to and at least 3 months after surgery. Primary outcomes were maturation and, for those that matured, time of functioning access, defined as the time from the first use to irreparable failure of the access. Secondary outcomes were time to maturation, complications, and time to first complication. Study group patients were 3.8 times more likely to experience fistula maturation compared to the controls (88% vs 66%, RR = 3.8, 95% confidence interval: 1.3-11.6, P = .016). Fewer patients in the study group had complications (76% vs 92%, P = .025), and the time from construction of the fistula to the first complication was longer (345.6 ± 441 days vs 198.3 ± 185.0 days, P = .025). Time to maturation was similar in both groups (119.3 ± 62.9 days vs 100.2 ± 61.7 days, P = .2). However, once matured, time to failure was significantly longer in the treatment group (903.7 ± 543.6 vs 381.6 ± 317.2 days, P = .001). Multivariate analysis confirmed that the likelihood of maturation was significantly higher in the treatment group patients. These results suggest that dialysis access patients may benefit from preoperative and postoperative cilostazol therapy. If confirmed by a randomized trial, this treatment will have a major beneficial impact on patients dependent on a well-functioning access for their hemodialysis.
Mesh-Begriff(e)	Aged ; Arteriovenous Shunt, Surgical/adverse effects ; Cardiovascular Agents/administration & dosage ; Cardiovascular Agents/adverse effects ; Case-Control Studies ; Drug Administration Schedule ; Female ; Humans ; Linear Models ; Logistic Models ; Male ; Multivariate Analysis ; Odds Ratio ; Phosphodiesterase 3 Inhibitors/administration & dosage ; Phosphodiesterase 3 Inhibitors/adverse effects ; Postoperative Complications/prevention & control ; Renal Dialysis ; Risk Factors ; Tetrazoles/administration & dosage ; Tetrazoles/adverse effects ; Time Factors ; Treatment Outcome
Chemische Substanzen	Cardiovascular Agents ; Phosphodiesterase 3 Inhibitors ; Tetrazoles ; cilostazol (N7Z035406B)
Sprache	Englisch
Erscheinungsdatum	2017-04
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	2076272-0
ISSN	1938-9116 ; 1538-5744
ISSN (online)	1938-9116
ISSN	1538-5744
DOI	10.1177/1538574417692464
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Buch ; Dissertation / Habilitation: Habitat selection by swift foxes in Badlands National Park and the surrounding area in South Dakota

Russell, Todd A

2006

Verfasserangabe	by Todd A. Russell
Schlagwörter	Kit fox/Habitat ; Foxes ; Wildlife reintroduction
Sprache	Englisch
Umfang	xv, 104 leaves :, ill., maps (some col.) ;, 28 cm.
Dokumenttyp	Buch ; Dissertation / Habilitation
Dissertation / Habilitation	Thesis (M.S.)--Wildlife and Fisheries Sciences Dept., South Dakota State University, 2006
Datenquelle	NAL Katalog (AGRICOLA)

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