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  1. Book ; Online: Low Back Pain (LBP)

    Denaro, Vincenzo / Iavicoli, Sergio / Russo, Fabrizio / Vadalà, Gianluca

    2022  

    Keywords Technology: general issues ; Environmental science, engineering & technology ; low back pain (LBP) ; standing position ; musculoskeletal pain ; sedentary behaviour ; back pain ; Google Trends ; infodemiology ; seasonality ; Wikipedia ; back problems ; Low Back Pain Scale ; maximum voluntary isometric contraction ; postural stability ; unexpected external postural perturbations ; disability ; insurance ; low back pain ; lumbar decompression ; lumbar fusion ; musculoskeletal disorders ; occupational health ; pain ; return to work ; satisfaction ; manual therapy ; kinesiophobia ; fear of pain ; Australian method ; Neurac ; chronic ; underserved ; African American ; Latino ; older adults ; workload ; wearable assistive device ; occupational back-support exoskeleton ; EMG ; handling task ; lumbalgia ; physical activity ; prevention ; public health ; occupational safety and health ; risk assessment ; occupational disorder ; knowledge ; rehabilitation nurses ; patient care ; unemployment ; gender difference ; population attributable fraction ; cross-sectional studies ; orthopaedics ; artificial intelligence ; computer vision ; digital image processing ; deep learning ; decision support systems ; computer aided diagnosis ; sub-threshold lumbar instability ; non-radiological lumbar instability ; lumbar instability ; radiography ; lumbar translation ; lumbar rotation ; screening tool ; X-ray ; sensitivity ; specificity ; workplace interventions ; workers ; work ability ; systematic review ; meta-analysis ; cognitive behavioral therapy ; mindfulness-based stress reduction ; depression ; fear-avoidance beliefs ; absenteeism ; epidemiology ; workplace ; epidural steroid injections ; lumbosacral radicular pain ; disk herniation ; canal stenosis ; review ; pelvic incidence ; hip-knee line ; anthropometry ; ROC curve ; reliability ; MRI ; CT ; bone metastasis ; bone cancer ; lung cancer ; prostate cancer ; machine learning ; radiomics ; signature ; spinal load ; core stability ; ergonomics ; low-back pain ; lower extremity
    Language 0|e
    Size 1 electronic resource (318 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021613827
    ISBN 9783036544564 ; 3036544569
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Anterior Cruciate Ligament Repair Augmented With Dynamic Intraligamentary Stabilization Is Equivalent to Hamstring Autograft Reconstruction at Short- and Mid-Term Follow-Up: A Systematic Review.

    Ambrosio, Luca / Franco, Domenico / Vadalà, Gianluca / Russo, Fabrizio / Papalia, Rocco

    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association

    2024  

    Abstract: Purpose: To compare clinical outcomes, knee stability and complications, failure, and revision rates after anterior cruciate ligament repair (ACLr) with dynamic intraligamentary stabilization (DIS) versus anterior cruciate ligament reconstruction (ACLR) ...

    Abstract Purpose: To compare clinical outcomes, knee stability and complications, failure, and revision rates after anterior cruciate ligament repair (ACLr) with dynamic intraligamentary stabilization (DIS) versus anterior cruciate ligament reconstruction (ACLR) with hamstring autograft for primary ACL ruptures at short and mid-term follow-up.
    Methods: A Preferred Reporting Items for Systematic Reviews and Meta-Analyses-compliant systematic review of PubMed/MEDLINE and Scopus was performed. Studies that evaluated patients undergoing ACLr with DIS or ACLR with hamstring autograft were considered for inclusion. Studies were excluded if patients were affected by concomitant meniscal, ligamentous, or chondral injuries needing surgical treatment, because of their potential confounding effect on postoperative outcomes. The Risk of Bias-2 tool was used to assess the risk of bias in the included studies. The quality of available evidence was rated according to Grading of Recommendations Assessment, Development, and Evaluation recommendations. The study protocol was registered in the PROSPERO database (ID: CRD42023394558).
    Results: Five randomized controlled trials comparing the outcomes of ACLr with DIS versus ACLR with hamstring autograft met the inclusion criteria. No major differences in terms of patient-reported outcomes (International Knee Documentation Committee subjective form, Lysholm score, Tegner activity scale, Knee injury and Osteoarthritis Outcome Score, visual analog scale satisfaction) or rates of complications, revisions, and failures were found in included studies at all time points. Repair showed greater International Knee Documentation Committee subjective form scores at 5 years in one study, whereas ACLR displayed significantly increased knee stability at 6 months and 5 years in 2 different studies, although the clinical relevance of these differences is doubtful.
    Conclusions: The results of this study suggest that ACLr with DIS is not inferior to ACLR with hamstring autograft in terms of rates of clinical outcomes, knee stability, risk of failure, complications, and revision surgery. Therefore, ACLr with DIS may be a viable alternative to ACLR with hamstring autograft in selected patients.
    Level of evidence: Level I, systematic review of Level I studies.
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 632528-2
    ISSN 1526-3231 ; 0749-8063
    ISSN (online) 1526-3231
    ISSN 0749-8063
    DOI 10.1016/j.arthro.2023.12.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online: Shapley-PC

    Russo, Fabrizio / Toni, Francesca

    Constraint-based Causal Structure Learning with Shapley Values

    2023  

    Abstract: Causal Structure Learning (CSL), amounting to extracting causal relations among the variables in a dataset, is widely perceived as an important step towards robust and transparent models. Constraint-based CSL leverages conditional independence tests to ... ...

    Abstract Causal Structure Learning (CSL), amounting to extracting causal relations among the variables in a dataset, is widely perceived as an important step towards robust and transparent models. Constraint-based CSL leverages conditional independence tests to perform causal discovery. We propose Shapley-PC, a novel method to improve constraint-based CSL algorithms by using Shapley values over the possible conditioning sets to decide which variables are responsible for the observed conditional (in)dependences. We prove soundness and asymptotic consistency and demonstrate that it can outperform state-of-the-art constraint-based, search-based and functional causal model-based methods, according to standard metrics in CSL.

    Comment: 18 pages (with appendix)
    Keywords Computer Science - Machine Learning ; Computer Science - Artificial Intelligence ; Statistics - Methodology
    Publishing date 2023-12-18
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Rehabilitation of sick-listed LBP patients in occupational health with collaboration of the workplace.

    Kokkonen, Valtteri / Lamminpää, Anne / Reijula, Kari / Russo, Fabrizio / Iavicoli, Sergio / Denaro, Vincenzo / Kuoppala, Jaana

    International journal of occupational medicine and environmental health

    2024  Volume 37, Issue 1, Page(s) 3–17

    Abstract: The aim was to evaluate if rehabilitation procedures including occupational health (OH) and workplace participation increase return to work (RTW) rates among patients with subacute and chronic low back pain (LBP). A systematic review of randomized ... ...

    Abstract The aim was to evaluate if rehabilitation procedures including occupational health (OH) and workplace participation increase return to work (RTW) rates among patients with subacute and chronic low back pain (LBP). A systematic review of randomized controlled trials was conducted using the PubMed and Cochrane databases. Main outcomes were RTW and days of sick leave. Interventions needed to be multidisciplinary including both OH and active workplace involvement in rehabilitation. Out of 1073 potentially eligible references, 8 met the inclusion criteria. Three studies had OH and 5 case managers involved in rehabilitation. Rehabilitation involving both OH and workplace improved RTW and decreased the number of sick leave days among LBP patients. Having case managers involved had no effect in RTW. In order to improve RTW, workplace visits and work ability meetings (WAMs) between OH and workplace are essential components in the rehabilitation process among patients with chronic LBP. Based on the study results, the authors suggest utilizing these co-operative interventions with workplaces in OH. High quality research investigating only the effect of WAMs in OH setting is needed in future. Int J Occup Med Environ Health. 2024;37(1):3-17.
    MeSH term(s) Humans ; Employment ; Low Back Pain/rehabilitation ; Occupational Health ; Return to Work ; Sick Leave ; Workplace ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2024-01-25
    Publishing country Poland
    Document type Journal Article ; Systematic Review
    ZDB-ID 1199049-1
    ISSN 1896-494X ; 0867-8383 ; 1232-1087
    ISSN (online) 1896-494X
    ISSN 0867-8383 ; 1232-1087
    DOI 10.13075/ijomeh.1896.02263
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Editorial: New perspectives and innovative techniques in contemporary spine surgery.

    Ambrosio, Luca / Vadalà, Gianluca / Russo, Fabrizio / Sakai, Daisuke / Denaro, Vincenzo

    Frontiers in surgery

    2023  Volume 10, Page(s) 1220181

    Language English
    Publishing date 2023-06-12
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2773823-1
    ISSN 2296-875X
    ISSN 2296-875X
    DOI 10.3389/fsurg.2023.1220181
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online: Causal Discovery and Injection for Feed-Forward Neural Networks

    Russo, Fabrizio / Toni, Francesca

    2022  

    Abstract: Neural networks have proven to be effective at solving a wide range of problems but it is often unclear whether they learn any meaningful causal relationship: this poses a problem for the robustness of neural network models and their use for high-stakes ... ...

    Abstract Neural networks have proven to be effective at solving a wide range of problems but it is often unclear whether they learn any meaningful causal relationship: this poses a problem for the robustness of neural network models and their use for high-stakes decisions. We propose a novel method overcoming this issue by injecting knowledge in the form of (possibly partial) causal graphs into feed-forward neural networks, so that the learnt model is guaranteed to conform to the graph, hence adhering to expert knowledge. This knowledge may be given up-front or during the learning process, to improve the model through human-AI collaboration. We apply our method to synthetic and real (tabular) data showing that it is robust against noise and can improve causal discovery and prediction performance in low data regimes.
    Keywords Computer Science - Machine Learning ; Computer Science - Artificial Intelligence ; Computer Science - Human-Computer Interaction ; Statistics - Machine Learning
    Subject code 006
    Publishing date 2022-05-19
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Intraoperative Cone-Beam Computed Tomography Navigation Versus 2-Dimensional Fluoroscopy in Single-Level Lumbar Spinal Fusion: A Comparative Analysis.

    Vadalà, Gianluca / Papalia, Giuseppe Francesco / Russo, Fabrizio / Brigato, Paolo / Ambrosio, Luca / Papalia, Rocco / Denaro, Vincenzo

    Neurospine

    2024  Volume 21, Issue 1, Page(s) 76–82

    Abstract: Objective: Several studies have advocated for the higher accuracy of transpedicular screw placement under cone-beam computed tomography (CBCT) compared to conventional 2-dimensional (2D) fluoroscopy. The superiority of navigation systems in ... ...

    Abstract Objective: Several studies have advocated for the higher accuracy of transpedicular screw placement under cone-beam computed tomography (CBCT) compared to conventional 2-dimensional (2D) fluoroscopy. The superiority of navigation systems in perioperative and postoperative outcomes remains a topic of debate. This study aimed to compare operative time, screw placement time and accuracy, total radiation dose, perioperative and postoperative outcomes in patients who underwent transpedicular screw fixation for degenerative lumbar spondylolisthesis (DLS) using intraoperative CBCT navigation versus 2D fluoroscopy.
    Methods: A retrospective analysis was conducted on patients affected by single-level DLS who underwent posterior lumbar instrumentation with transpedicular screw fixation using surgical CBCT navigation (NV group) or 2D fluoroscopy-assisted freehand technique (FH group). Demographics, screw placement time and accuracy, operative time, total radiation dose, intraoperative blood loss, screw revision rate, complications, and length of stay (LOS) were assessed.
    Results: The study included a total of 30 patients (NV group: n = 15; FH group: n = 15). The mean screw placement time, operative time, and LOS were significantly reduced in the NV group compared to the FH group (p < 0.05). The total radiation dose was significantly higher in the NV group (p < 0.0001). No significant difference was found in terms of blood loss and postoperative complications.
    Conclusion: This study suggests that intraoperative CBCT-navigated single-level lumbar transpedicular screw fixation is superior in terms of mean screw placement time, operative time, and LOS compared to 2D fluoroscopy, despite a higher intraoperative radiation exposure.
    Language English
    Publishing date 2024-03-31
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3031654-6
    ISSN 2586-6591 ; 2586-6583
    ISSN (online) 2586-6591
    ISSN 2586-6583
    DOI 10.14245/ns.2347106.553
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Functional Tests Predicting Return to Work of Workers with Non-Specific Low Back Pain: Are There Any Validated and Usable Functional Tests for Occupational Health Services in Everyday Practice? A Systematic Review.

    Hurri, Heikki / Vänni, Toni / Muttonen, Elli / Russo, Fabrizio / Iavicoli, Sergio / Ristolainen, Leena

    International journal of environmental research and public health

    2023  Volume 20, Issue 6

    Abstract: The literature predominantly advocates subjective perception of disability and pain as an outcome measure for the functional evaluation of patients with low back pain (LBP). Physical outcome measurements are almost completely ignored. In this systematic ... ...

    Abstract The literature predominantly advocates subjective perception of disability and pain as an outcome measure for the functional evaluation of patients with low back pain (LBP). Physical outcome measurements are almost completely ignored. In this systematic review, we focused on physical functional measurements that can contribute to the prediction of patients' return to work (RTW) readiness after sick leave or rehabilitation. Searches were conducted in July 2022 without any time limit in the Cochrane Library, PEDro, PubMed and Scopus databases for functional and clinical tests reliable and applicable in clinical practice without demanding equipment. Two independent researchers extracted the data from the included articles in a standardised data collection form, and a third researcher validated the data extraction. No date restriction was applied. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines in conducting the review. We found seven original articles, including six with an impact on predicting RTW. We found four fair and three poor original studies fulfilling our criteria. We found the Back Performance Scale (BPS) and back endurance test to be the most promising tests for occupational health service and the clinical practitioner. Radiation of back pain, with or without neurological deficiencies, had some predictive value in terms of RTW, too. The working conditions vary a lot, which causes inconsistency in the studies and in their interpretation. Functional tests could complete the widely used working ability evaluations methods such as the Work Ability Index (WAI) and are worth considering for future research. Overall, more research is needed in this field. The question of when LBP patients can resume everyday activities and work is not possible to determine with functional tests alone. Psychosocial aspects and work demands must be considered. PROSPERO: CRD42022353955. The study was funded by the University of Helsinki.
    MeSH term(s) Humans ; Low Back Pain ; Return to Work ; Occupational Health Services ; Back Pain ; Employment ; Sick Leave
    Language English
    Publishing date 2023-03-15
    Publishing country Switzerland
    Document type Systematic Review ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20065188
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Threats and opportunities of using ChatGPT in scientific writing-The risk of getting spine

    Ambrosio, Luca / Schol, Jordy / La Pietra, Vincenzo Amedeo / Russo, Fabrizio / Vadalà, Gianluca / Sakai, Daisuke

    JOR spine

    2023  Volume 7, Issue 1, Page(s) e1296

    Abstract: ChatGPT and AI chatbots are revolutionizing several science fields, including medical writing. However, the inadequate use of such advantageous tools can raise numerous methodological and ethical issues. ...

    Abstract ChatGPT and AI chatbots are revolutionizing several science fields, including medical writing. However, the inadequate use of such advantageous tools can raise numerous methodological and ethical issues.
    Language English
    Publishing date 2023-12-13
    Publishing country United States
    Document type Journal Article
    ISSN 2572-1143
    ISSN (online) 2572-1143
    DOI 10.1002/jsp2.1296
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: What is the CSR’s focus in healthcare?

    Russo, Fabrizio

    Journal of business ethics : JOBE Vol. 134, No. 2 , p. 323-334

    2016  Volume 134, Issue 2, Page(s) 323–334

    Author's details Fabrizio Russo
    Keywords Corporate social responsibility ; Healthcare ; Local community ; Appropriateness ; Social impact ; Competitiveness
    Language English
    Publisher Springer
    Publishing place Dordrecht
    Document type Article
    ZDB-ID 868017-6 ; 1478688-6
    ISSN 1573-0697 ; 0167-4544
    ISSN (online) 1573-0697
    ISSN 0167-4544
    Database ECONomics Information System

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