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  1. AU="Rutherford, Anna"
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  1. Article ; Online: How Hepatologists Use Liver Biopsy in the Evaluation of Liver Disease?

    Mitten, Emilie K / Rutherford, Anna

    Surgical pathology clinics

    2023  Volume 16, Issue 3, Page(s) 443–456

    Abstract: This article focuses on how hepatologists view the role of liver biopsy in diagnosis, assessment, and management of chronic and acute liver disease, and its variable use among different etiologies of liver disease and in the evaluation of liver fibrosis. ...

    Abstract This article focuses on how hepatologists view the role of liver biopsy in diagnosis, assessment, and management of chronic and acute liver disease, and its variable use among different etiologies of liver disease and in the evaluation of liver fibrosis.
    MeSH term(s) Humans ; Gastroenterologists ; Liver Cirrhosis/diagnosis ; Liver Cirrhosis/pathology ; Biopsy
    Language English
    Publishing date 2023-06-11
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1875-9157
    ISSN (online) 1875-9157
    DOI 10.1016/j.path.2023.04.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Practical Tips for Putting Telework Into (Medical) Practice.

    Rutherford, Anna / Henderson, Wendy

    Family practice management

    2023  Volume 30, Issue 5, Page(s) 33–37

    MeSH term(s) Humans ; Teleworking
    Language English
    Publishing date 2023-09-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1226804-5
    ISSN 1531-1929 ; 1069-5648
    ISSN (online) 1531-1929
    ISSN 1069-5648
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    Zs.A 4233: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Role of Speech Pathology in a Multidisciplinary Approach to a Patient With Mild Traumatic Brain Injury.

    Rutherford, Anna / Markley, Lisa / Henderson, Wendy

    Federal practitioner : for the health care professionals of the VA, DoD, and PHS

    2020  Volume 38, Issue 3, Page(s) 136–139

    Language English
    Publishing date 2020-12-24
    Publishing country United States
    Document type Case Reports
    ISSN 1078-4497
    ISSN 1078-4497
    DOI 10.12788/fp.0097
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Quantitative Analysis of Liver Disease Using MRI-Based Radiomic Features of the Liver and Spleen.

    Sack, Jordan / Nitsch, Jennifer / Meine, Hans / Kikinis, Ron / Halle, Michael / Rutherford, Anna

    Journal of imaging

    2022  Volume 8, Issue 10

    Abstract: Background: Radiomics extracts quantitative image features to identify biomarkers for characterizing disease. Our aim was to characterize the ability of radiomic features extracted from magnetic resonance (MR) imaging of the liver and spleen to detect ... ...

    Abstract Background: Radiomics extracts quantitative image features to identify biomarkers for characterizing disease. Our aim was to characterize the ability of radiomic features extracted from magnetic resonance (MR) imaging of the liver and spleen to detect cirrhosis by comparing features from patients with cirrhosis to those without cirrhosis.
    Methods: This retrospective study compared MR-derived radiomic features between patients with cirrhosis undergoing hepatocellular carcinoma screening and patients without cirrhosis undergoing intraductal papillary mucinous neoplasm surveillance between 2015 and 2018 using the same imaging protocol. Secondary analyses stratified the cirrhosis cohort by liver disease severity using clinical compensation/decompensation and Model for End-Stage Liver Disease (MELD).
    Results: Of 167 patients, 90 had cirrhosis with 68.9% compensated and median MELD 8. Combined liver and spleen radiomic features generated an AUC 0.94 for detecting cirrhosis, with shape and texture components contributing more than size. Discrimination of cirrhosis remained high after stratification by liver disease severity.
    Conclusions: MR-based liver and spleen radiomic features had high accuracy in identifying cirrhosis, after stratification by clinical compensation/decompensation and MELD. Shape and texture features performed better than size features. These findings will inform radiomic-based applications for cirrhosis diagnosis and severity.
    Language English
    Publishing date 2022-10-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2824270-1
    ISSN 2313-433X ; 2313-433X
    ISSN (online) 2313-433X
    ISSN 2313-433X
    DOI 10.3390/jimaging8100277
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  5. Article ; Online: Quantitative Analysis of Liver Disease Using MRI-Based Radiomic Features of the Liver and Spleen

    Sack, Jordan / Nitsch, Jennifer / Meine, Hans / Kikinis, Ron / Halle, Michael W. / Rutherford, Anna

    2022  

    Abstract: Background: Radiomics extracts quantitative image features to identify biomarkers for characterizing disease. Our aim was to characterize the ability of radiomic features extracted from magnetic resonance (MR) imaging of the liver and spleen to detect ... ...

    Abstract Background: Radiomics extracts quantitative image features to identify biomarkers for characterizing disease. Our aim was to characterize the ability of radiomic features extracted from magnetic resonance (MR) imaging of the liver and spleen to detect cirrhosis by comparing features from patients with cirrhosis to those without cirrhosis. Methods: This retrospective study compared MR-derived radiomic features between patients with cirrhosis undergoing hepatocellular carcinoma screening and patients without cirrhosis undergoing intraductal papillary mucinous neoplasm surveillance between 2015 and 2018 using the same imaging protocol. Secondary analyses stratified the cirrhosis cohort by liver disease severity using clinical compensation/decompensation and Model for End-Stage Liver Disease (MELD). Results: Of 167 patients, 90 had cirrhosis with 68.9% compensated and median MELD 8. Combined liver and spleen radiomic features generated an AUC 0.94 for detecting cirrhosis, with shape and texture components contributing more than size. Discrimination of cirrhosis remained high after stratification by liver disease severity. Conclusions: MR-based liver and spleen radiomic features had high accuracy in identifying cirrhosis, after stratification by clinical compensation/decompensation and MELD. Shape and texture features performed better than size features. These findings will inform radiomic-based applications for cirrhosis diagnosis and severity.

    8

    10
    Keywords cirrhosis ; diagnosis ; MRI ; radiomics ; severity ; spleen
    Subject code 610
    Language English
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: A New Approach to New Physician Orientation: Six Key Components.

    Henderson, Wendy / Parker, Mary / Rutherford, Anna / Hayes, Brian P

    Family practice management

    2019  Volume 26, Issue 4, Page(s) 24–28

    MeSH term(s) Checklist ; Humans ; Inservice Training/methods ; Inservice Training/trends ; Interprofessional Relations ; Physicians/psychology ; Social Support
    Language English
    Publishing date 2019-07-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1226804-5
    ISSN 1531-1929 ; 1069-5648
    ISSN (online) 1531-1929
    ISSN 1069-5648
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4233: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Intraperitoneal corticosteroids for recurrent ascites in patients with Fontan circulation: Initial clinical experience.

    Wu, Fred M / Valente, Anne M / Nigrovic, Peter A / Rutherford, Anna E / Singh, Michael N

    Journal of cardiac surgery

    2020  Volume 36, Issue 2, Page(s) 735–738

    Abstract: Individuals with single-ventricle congenital heart disease who are palliated to a Fontan circulation are at risk for heart failure and liver disease, with recurrent ascites being a potentially debilitating cause of late morbidity. Although ascites ... ...

    Abstract Individuals with single-ventricle congenital heart disease who are palliated to a Fontan circulation are at risk for heart failure and liver disease, with recurrent ascites being a potentially debilitating cause of late morbidity. Although ascites associated with heart failure or liver failure is usually characterized by a high serum-ascites albumin gradient (SAAG), we have observed multiple instances of ascites in Fontan patients with low SAAG, suggesting an inflammatory process. We present three cases in which recalcitrant ascites severely and adversely impacted the quality of life and describe our initial experience with intraperitoneal corticosteroids in this setting.
    MeSH term(s) Adrenal Cortex Hormones ; Ascites/drug therapy ; Ascites/etiology ; Fontan Procedure ; Heart Defects, Congenital/complications ; Heart Defects, Congenital/surgery ; Humans ; Quality of Life
    Chemical Substances Adrenal Cortex Hormones
    Language English
    Publishing date 2020-12-11
    Publishing country United States
    Document type Case Reports
    ZDB-ID 639059-6
    ISSN 1540-8191 ; 0886-0440
    ISSN (online) 1540-8191
    ISSN 0886-0440
    DOI 10.1111/jocs.15244
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    Zs.A 2221: Show issues Location:
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  8. Article ; Online: Hemodynamic Effects of Paracentesis in a Patient With a Fontan Circulation.

    Rajpal, Saurabh / Opotowsky, Alexander R / Rutherford, Anna / Wu, Fred

    World journal for pediatric & congenital heart surgery

    2018  Volume 10, Issue 3, Page(s) 357–359

    Abstract: Recurrent ascites is a common manifestation of failing Fontan circulation. We present the hemodynamic response to large-volume paracentesis in a patient with Fontan circulation and Fontan-associated liver disease, documenting an immediate and substantial ...

    Abstract Recurrent ascites is a common manifestation of failing Fontan circulation. We present the hemodynamic response to large-volume paracentesis in a patient with Fontan circulation and Fontan-associated liver disease, documenting an immediate and substantial decline in systemic venous pressure and increase in cardiac output. These preliminary observations may have implications for the management of ascites in adults with Fontan circulation.
    MeSH term(s) Adult ; Ascites/etiology ; Ascites/surgery ; Female ; Fontan Procedure/methods ; Heart Defects, Congenital/complications ; Heart Defects, Congenital/physiopathology ; Heart Defects, Congenital/surgery ; Hemodynamics/physiology ; Humans ; Paracentesis/methods
    Language English
    Publishing date 2018-10-24
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2550261-X
    ISSN 2150-136X ; 2150-1351
    ISSN (online) 2150-136X
    ISSN 2150-1351
    DOI 10.1177/2150135118779351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: MRI-based radiomic feature analysis of end-stage liver disease for severity stratification.

    Nitsch, Jennifer / Sack, Jordan / Halle, Michael W / Moltz, Jan H / Wall, April / Rutherford, Anna E / Kikinis, Ron / Meine, Hans

    International journal of computer assisted radiology and surgery

    2021  Volume 16, Issue 3, Page(s) 457–466

    Abstract: Purpose: We aimed to develop a predictive model of disease severity for cirrhosis using MRI-derived radiomic features of the liver and spleen and compared it to the existing disease severity metrics of MELD score and clinical decompensation. The MELD ... ...

    Abstract Purpose: We aimed to develop a predictive model of disease severity for cirrhosis using MRI-derived radiomic features of the liver and spleen and compared it to the existing disease severity metrics of MELD score and clinical decompensation. The MELD score is compiled solely by blood parameters, and so far, it was not investigated if extracted image-based features have the potential to reflect severity to potentially complement the calculated score.
    Methods: This was a retrospective study of eligible patients with cirrhosis ([Formula: see text]) who underwent a contrast-enhanced MR screening protocol for hepatocellular carcinoma (HCC) screening at a tertiary academic center from 2015 to 2018. Radiomic feature analyses were used to train four prediction models for assessing the patient's condition at time of scan: MELD score, MELD score [Formula: see text] 9 (median score of the cohort), MELD score [Formula: see text] 15 (the inflection between the risk and benefit of transplant), and clinical decompensation. Liver and spleen segmentations were used for feature extraction, followed by cross-validated random forest classification.
    Results: Radiomic features of the liver and spleen were most predictive of clinical decompensation (AUC 0.84), which the MELD score could predict with an AUC of 0.78. Using liver or spleen features alone had slightly lower discrimination ability (AUC of 0.82 for liver and AUC of 0.78 for spleen features only), although this was not statistically significant on our cohort. When radiomic prediction models were trained to predict continuous MELD scores, there was poor correlation. When stratifying risk by splitting our cohort at the median MELD 9 or at MELD 15, our models achieved AUCs of 0.78 or 0.66, respectively.
    Conclusions: We demonstrated that MRI-based radiomic features of the liver and spleen have the potential to predict the severity of liver cirrhosis, using decompensation or MELD status as imperfect surrogate measures for disease severity.
    MeSH term(s) Adult ; Aged ; Algorithms ; Area Under Curve ; Carcinoma, Hepatocellular/diagnostic imaging ; End Stage Liver Disease/diagnostic imaging ; Female ; Humans ; Image Processing, Computer-Assisted/methods ; Liver/diagnostic imaging ; Liver Cirrhosis/diagnostic imaging ; Liver Neoplasms/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Severity of Illness Index ; Spleen/diagnostic imaging
    Language English
    Publishing date 2021-03-01
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2365628-1
    ISSN 1861-6429 ; 1861-6410
    ISSN (online) 1861-6429
    ISSN 1861-6410
    DOI 10.1007/s11548-020-02295-9
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    Zs.A 6615: Show issues Location:
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  10. Book ; Conference proceedings ; Online: Bodies and voices

    Borch, Merete Falck / Rutherford, Anna

    the force-field of representation and discourse in colonial and postcolonial studies

    (Cross / cultures : Readings in the post/colonial literatures in English ; 94)

    2008  

    Abstract: A wide-ranging collection of essays centred on readings of the body in contemporary literary and socio-anthropological discourse, from slavery and rape to female genital mutilation, from clothing, ocular pornography, voice, deformation and transmutation ... ...

    Institution European Association for Commonwealth Literature and Language Studies / Conference ((2002, Copenhagen, Denmark))
    ebrary, Inc
    Author's details edited by Merete Falck Borch ... [et al.]
    Series title Cross / cultures : Readings in the post/colonial literatures in English ; 94
    Abstract A wide-ranging collection of essays centred on readings of the body in contemporary literary and socio-anthropological discourse, from slavery and rape to female genital mutilation, from clothing, ocular pornography, voice, deformation and transmutation to the imprisoned, dismembered, remembered, abducted or ghostly body, in Africa, Australasia and the Pacific, Canada, the Caribbean, Great Britain and Eire
    Keywords Human body/Social aspects ; Human body in literature ; Imperialism in literature ; Literature/History and criticism ; Postcolonialism in literature
    Language English
    Size Online-Ressource (xl, 459 p)
    Publisher Rodopi
    Publishing place Amsterdam ;New York
    Document type Book ; Conference proceedings ; Online
    Note Includes bibliographical references and index ; Papers originally presented at the conference of the European Association for Commonwealth Literature and Language Studies held in Copenhagen, Denmark in 2002 ; Volume dedicated to Anna Rutherford, 1932-2001
    ISBN 9042023341 ; 9789042023345
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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