LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 4 of total 4

Search options

  1. Article ; Online: The Effect of Enzyme Activity on Carbon Sequestration and the Cycle of Available Macro- (P, K, Mg) and Microelements (Zn, Cu) in Phaeozems

    Lemanowicz, Joanna / Bartkowiak, Agata / Zielińska, Aleksandra / Jaskulska, Iwona / Rydlewska, Magdalena / Klunek, Katarzyna / Polkowska, Magdalena

    Agriculture. 2023 Jan. 10, v. 13, no. 1

    2023  

    Abstract: The study objective was to determine the relationship of selected enzyme activities with carbon sequestration and N, P, K, Mg, Zn and Cu contents in Phaeozem soils. Soil samples were taken from a 10 ha area. A selection of their physical and chemical ... ...

    Abstract The study objective was to determine the relationship of selected enzyme activities with carbon sequestration and N, P, K, Mg, Zn and Cu contents in Phaeozem soils. Soil samples were taken from a 10 ha area. A selection of their physical and chemical properties and the contents of the available forms of selected macro- and microelements were determined. The activities of dehydrogenases (DEH), catalase (CAT), peroxidases (PER), alkaline (AlP) and acid (AcP) phosphatase, β-glucosidase (BG) and proteases (PR) were also determined. The relationship between enzymatic soil fertility indices (AlP/AcP, BIF, GMea, TEI, BA12 and BA13) and selected soil parameters was also determined. The research used principal component analysis (PCA) to distinguish significantly correlated parameters of a Phaeozem used for agricultural purposes. The study area showed low TOC and K contents and average P and Mg contents. Significant positive correlations were found between the TOC content and activity of the tested enzymes, evidencing that soil enzymes are an important parameter in carbon sequestration and soil nutrient dynamics.
    Keywords Phaeozems ; agriculture ; carbon sequestration ; catalase ; enzyme activity ; principal component analysis ; proteinases ; soil fertility ; soil nutrient dynamics
    Language English
    Dates of publication 2023-0110
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2651678-0
    ISSN 2077-0472
    ISSN 2077-0472
    DOI 10.3390/agriculture13010172
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Diverse expression of N-acetylglucosaminyltransferase V and complex-type β1,6-branched N-glycans in uveal and cutaneous melanoma cells.

    Pocheć, Ewa / Rydlewska, Magdalena / Przybyło, Małgorzata / Lityńska, Anna

    Acta biochimica Polonica

    2015  Volume 62, Issue 2, Page(s) 323–328

    Abstract: Although both uveal (UM) and cutaneous (CM) melanoma cells derive from the transformed melanocytes, their biology varies significantly in several aspects. Malignant transformation is frequently associated with alternations in cell glycosylation, in ... ...

    Abstract Although both uveal (UM) and cutaneous (CM) melanoma cells derive from the transformed melanocytes, their biology varies significantly in several aspects. Malignant transformation is frequently associated with alternations in cell glycosylation, in particular those concerning branched complex-type N-glycans. These changes occur principally in β1,4-N-acetylglucosaminyltransferase III (GnT-III) that catalyzes the synthesis of glycans with bisected N-acetylglucosamine (GlcNAc) and β1,6-N-acetylglucosaminyltransferase V (GnT-V) that is involved in forming β1,6-branched antenna in complex-type glycans. We searched for the reasons of a different behavior of CM and UM cells in the expression of GnT-III and GnT-V and their oligosaccharide products. Our study showed that UM cells have more β1,6-branched glycans than CM cells, what results from a higher expression of MGAT5 gene encoding GnT-V. The higher β1,6-branching of glycans in UM may contribute to their higher potential to migrate on fibronectin and weaker binding to main extracellular matrix proteins, observed in our previous studies.
    MeSH term(s) Cell Line, Tumor ; Cell Movement ; Gene Expression Regulation, Neoplastic ; Glycosylation ; Humans ; Melanoma/genetics ; Melanoma/metabolism ; Melanoma/pathology ; N-Acetylglucosaminyltransferases/genetics ; N-Acetylglucosaminyltransferases/metabolism ; Polysaccharides/chemistry ; Polysaccharides/metabolism ; Skin Neoplasms/genetics ; Skin Neoplasms/metabolism ; Uveal Neoplasms/genetics ; Uveal Neoplasms/metabolism ; Uveal Neoplasms/pathology
    Chemical Substances Polysaccharides ; Mgat5 protein, human (EC 2.4.1.-) ; N-Acetylglucosaminyltransferases (EC 2.4.1.-) ; beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase (EC 2.4.1.144) ; alpha-1,6-mannosylglycoprotein beta 1,6-N-acetylglucosaminyltransferase (EC 2.4.1.155)
    Language English
    Publishing date 2015
    Publishing country Poland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 595762-x
    ISSN 1734-154X ; 0001-527X
    ISSN (online) 1734-154X
    ISSN 0001-527X
    DOI 10.18388/abp.2015_1050
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 232: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Aberrant glycosylation of αvβ3 integrin is associated with melanoma progression.

    Pocheć, Ewa / Bubka, Monika / Rydlewska, Magdalena / Janik, Marcelina / Pokrywka, Małgorzata / Lityńska, Anna

    Anticancer research

    2015  Volume 35, Issue 4, Page(s) 2093–2103

    Abstract: N-glycosylation of integrins plays an important role in cancer progression. Increased αvβ3 integrin expression during melanoma progression is well-documented but the role of its glycans in tumorigenesis is still poorly understood. In the present study we ...

    Abstract N-glycosylation of integrins plays an important role in cancer progression. Increased αvβ3 integrin expression during melanoma progression is well-documented but the role of its glycans in tumorigenesis is still poorly understood. In the present study we used the WM793 primary melanoma cell line and its highly metastatic variant, WM1205Lu, to examine αvβ3 glycosylation. Lectin precipitation, enzyme digestion and the use of swainsonine (SW) showed that αvβ3 integrin glycosylation differs significantly between primary and metastatic melanoma cells. High-mannose structures and complex glycans with bisecting N-acetylglucosamine (GlcNAc) were more abundant in both subunits of primary cells. We also observed a shift in the sialylation of αvβ3 integrin related to reduction of α2-6-linked sialic acid expression and an increase of α2-3 sialylation of both subunits in melanoma progression. Metastatic melanoma migration on vitronectin (VN) was reduced in the presence of antibody against αvβ3 and the lectins phytohemagglutinin-L (PHA-L), Sambucus nigra agglutinin (SNA) and Maackia amurensis (MAA) in woundhealing assays. Our results show that the acquisition of metastatic competence by melanoma cells is accompanied by alteration of αvβ3 integrin glycosylation and that both αvβ3 and β1-6-branched sialylated complex-type N-glycans promote metastatic melanoma migration on VN.
    MeSH term(s) Cell Adhesion/genetics ; Cell Line, Tumor ; Cell Movement/drug effects ; Disease Progression ; Glycosylation ; Humans ; Integrin alphaVbeta3/genetics ; Integrin alphaVbeta3/metabolism ; Melanoma/metabolism ; Melanoma/pathology ; N-Acetylneuraminic Acid/metabolism ; Vitronectin/administration & dosage
    Chemical Substances Integrin alphaVbeta3 ; Vitronectin ; N-Acetylneuraminic Acid (GZP2782OP0)
    Language English
    Publishing date 2015-04
    Publishing country Greece
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 604549-2
    ISSN 1791-7530 ; 0250-7005
    ISSN (online) 1791-7530
    ISSN 0250-7005
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1642: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Decreased Immunoglobulin G Core Fucosylation, A Player in Antibody-dependent Cell-mediated Cytotoxicity, is Associated with Autoimmune Thyroid Diseases.

    Martin, Tiphaine C / Šimurina, Mirna / Ząbczyńska, Marta / Martinic Kavur, Marina / Rydlewska, Magdalena / Pezer, Marija / Kozłowska, Kamila / Burri, Andrea / Vilaj, Marija / Turek-Jabrocka, Renata / Krnjajić-Tadijanović, Milena / Trofimiuk-Müldner, Małgorzata / Ugrina, Ivo / Lityńska, Anna / Hubalewska-Dydejczyk, Alicja / Trbojevic-Akmacic, Irena / Lim, Ee Mun / Walsh, John P / Pocheć, Ewa /
    Spector, Tim D / Wilson, Scott G / Lauc, Gordan

    Molecular & cellular proteomics : MCP

    2020  Volume 19, Issue 5, Page(s) 774–792

    Abstract: Autoimmune thyroid diseases (AITD) are the most common group of autoimmune diseases, associated with lymphocyte infiltration and the production of thyroid autoantibodies, like thyroid peroxidase antibodies (TPOAb), in the thyroid gland. Immunoglobulins ... ...

    Abstract Autoimmune thyroid diseases (AITD) are the most common group of autoimmune diseases, associated with lymphocyte infiltration and the production of thyroid autoantibodies, like thyroid peroxidase antibodies (TPOAb), in the thyroid gland. Immunoglobulins and cell-surface receptors are glycoproteins with distinctive glycosylation patterns that play a structural role in maintaining and modulating their functions. We investigated associations of total circulating IgG and peripheral blood mononuclear cells glycosylation with AITD and the influence of genetic background in a case-control study with several independent cohorts and over 3,000 individuals in total. The study revealed an inverse association of IgG core fucosylation with TPOAb and AITD, as well as decreased peripheral blood mononuclear cells antennary α1,2 fucosylation in AITD, but no shared genetic variance between AITD and glycosylation. These data suggest that the decreased level of IgG core fucosylation is a risk factor for AITD that promotes antibody-dependent cell-mediated cytotoxicity previously associated with TPOAb levels.
    MeSH term(s) Adult ; Antibody-Dependent Cell Cytotoxicity ; Autoimmune Diseases/immunology ; Blood Cells/metabolism ; Cohort Studies ; Fucose/metabolism ; Gene Expression Regulation ; Glycomics ; Glycosylation ; Humans ; Immunoglobulin G/genetics ; Immunoglobulin G/metabolism ; Iodide Peroxidase/immunology ; Linkage Disequilibrium/genetics ; Models, Biological ; Polymorphism, Single Nucleotide/genetics ; Polysaccharides/metabolism ; Thyroid Diseases/immunology
    Chemical Substances Immunoglobulin G ; Polysaccharides ; Fucose (28RYY2IV3F) ; Iodide Peroxidase (EC 1.11.1.8)
    Language English
    Publishing date 2020-02-05
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Twin Study
    ZDB-ID 2075924-1
    ISSN 1535-9484 ; 1535-9476
    ISSN (online) 1535-9484
    ISSN 1535-9476
    DOI 10.1074/mcp.RA119.001860
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 5599: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top