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Article ; Online: Controversies in point-of-care 3D printing for oncological and reconstructive surgery with free software in oral and maxillofacial surgery: European regulations, costs, and timeframe.

Gómez, V J / Martín-González, A / Zafra-Vallejo, V / Zubillaga-Rodríguez, I / Fernández-García, A / Sánchez-Aniceto, G

International journal of oral and maxillofacial surgery

2024

Abstract: The aim of this paper is to discuss the controversies surrounding the most recent European regulations, as well as the cost, for a 3D printing workflow using free-source software in the context of a tertiary level university hospital in the Spanish ... ...

Abstract	The aim of this paper is to discuss the controversies surrounding the most recent European regulations, as well as the cost, for a 3D printing workflow using free-source software in the context of a tertiary level university hospital in the Spanish public health system. Computer-aided design and manufacturing (CAD/CAM) for head and neck oncological surgery with the printing of biomodels, cutting guides, and patient-specific implants has made it possible to simplify and make this type of highly complex surgery more predictable. This technology is not without drawbacks, such as increased costs and the lead times when planning with the biomedical industry. A review of the current European legislation and the literature on this subject was performed, and comparisons made with the authors' in-house 3D printing setup using free software and different 3D printers. The cost analysis revealed that for the cheapest setup with free software, it would be possible to amortize the investment from case 2, and in all cases the initial investment would be amortized before case 9. The timeframe ranged from 2 weeks with the biomedical industry to 72 h with point-of-care 3D printing. It is now possible to develop point-of-care 3D printing in any hospital with almost any budget.
Language	English
Publishing date	2024-01-29
Publishing country	Denmark
Document type	Journal Article
ZDB-ID	353721-3
ISSN	1399-0020 ; 0901-5027
ISSN (online)	1399-0020
ISSN	0901-5027
DOI	10.1016/j.ijom.2024.01.005
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Article ; Online: A retrospective risk factor analysis of infection and wound dehiscence following guided bone regeneration in cystectomy defects of the jaws.

Carbonell-Asins, Pilar / Sánchez Aniceto, Gregorio

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery

2022 Volume 50, Issue 8, Page(s) 657–663

Abstract: This study's objective is to determine if the combined use of bone substitutes and collagen membranes is related to worse postoperative outcomes after intra-osseous oral cystectomies. Additional risk factors mentioned in the existing literature were ... ...

Abstract	This study's objective is to determine if the combined use of bone substitutes and collagen membranes is related to worse postoperative outcomes after intra-osseous oral cystectomies. Additional risk factors mentioned in the existing literature were retrospectively analysed by reviewing the medical records and imaging tests of adult patients. Age, gender, smoking habit, cyst location, size, shape, histopathology, perilesional osteosclerosis and associated intracystic third molars were registered. The type of biomaterials applied and the number of bony walls remaining after surgery were also identified. All factors were analysed in relation to wound dehiscence and postoperative infection. Simple and multiple logistic regression analyses were performed to exclude possible confounding effects between the risk factors identified. In a sample of 211 cystectomies, guided bone regeneration was not significantly associated with infection, only the presence of impacted third molars was (p = 0.0219). This finding remained true, even in cysts larger than 25 mm. However, the risk of wound dehiscence was 4.9 times higher when biomaterials were applied (CI 95%, 1.6818-12.8274, p = 0.0014). In accordance with recent studies, these findings suggest that whenever guided bone regeneration might prove useful after cyst enucleation, avoiding chemically cross-linked membranes should be considered.
MeSH term(s)	Adult ; Biocompatible Materials ; Bone Substitutes/therapeutic use ; Cystectomy/adverse effects ; Cysts ; Factor Analysis, Statistical ; Guided Tissue Regeneration, Periodontal/adverse effects ; Guided Tissue Regeneration, Periodontal/methods ; Humans ; Jaw ; Membranes, Artificial ; Postoperative Complications/etiology ; Retrospective Studies ; Risk Factors ; Surgical Wound Dehiscence/etiology
Chemical Substances	Biocompatible Materials ; Bone Substitutes ; Membranes, Artificial
Language	English
Publishing date	2022-07-05
Publishing country	Scotland
Document type	Journal Article
ZDB-ID	91267-0
ISSN	1878-4119 ; 1010-5182 ; 0301-0503
ISSN (online)	1878-4119
ISSN	1010-5182 ; 0301-0503
DOI	10.1016/j.jcms.2022.06.008
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Article: In-and-out Technique: An In-house Efficient Predictive Hole Fabrication Workflow.

Asensio-Salazar, Javier / Rivero Calle, Alvaro / Olavarría Montes, Eduardo / Delgado Fernández, Alejandro / Zubillaga Rodríguez, Ignacio / Gutiérrez Díaz, Ramon / Sánchez Aniceto, Gregorio

Plastic and reconstructive surgery. Global open

2024 Volume 12, Issue 4, Page(s) e5702

Abstract: Virtual surgical planning (VSP) and three-dimensional (3D) printing can increase precision and reduce surgical time in craniofacial reconstruction. However, the elevated cost and manufacturing time of outsourced workflows is increasing the development of ...

Abstract	Virtual surgical planning (VSP) and three-dimensional (3D) printing can increase precision and reduce surgical time in craniofacial reconstruction. However, the elevated cost and manufacturing time of outsourced workflows is increasing the development of in-house solutions. One of the main challenges in in-house workflows is to create cutting guides that hold plate position information. This is due to the fact that hospitals usually lack the infrastructure required to design and 3D print custom-made plates. Including plate-positioning information in resection guides is especially relevant in complex reconstructions and when tumor extension limits plate placement before resection. Current in-house workflows revolve around the idea of 3D scanning the bent plate's shape and to fuse it with the VSP. The goal of this article is to share our technique to transfer plate position information to resection guides. Our protocol uses a 3D model of the reconstruction as an intermediate step to transfer the plate position of a bent stock reconstruction plate to cutting guides. Two patients who required mandibular reconstruction with fibula flap are presented to illustrate the technique. This workflow requires a 3D-printed model of the desired outcome, cutting guides, and a stock plate. Results were satisfactory in terms of cutting location and angulation, plate adaptation and condylar position. This technique allows for a simple, safe, cheap, and quick alternative to add reconstruction plate information to cutting guides.
Language	English
Publishing date	2024-04-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	2851682-5
ISSN	2169-7574 ; 2169-7574
ISSN (online)	2169-7574
ISSN	2169-7574
DOI	10.1097/GOX.0000000000005702
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Article: Clinical Case and Literature Review of a Potentially Life-Threatening Complication Derived from Mouth Floor Hematoma after Implant Surgery

Carreira-Nestares, Beatriz / Urquiza-Fornovi, Irene / Carreira-Delgado, Manuel Carlos / Gutierrez-Díaz, Ramón / Sánchez-Aniceto, Gregorio

European Dental Research and Biomaterials Journal

2024

Abstract: The placement of dental implants is a safe and predictable procedure when performed by qualified staff. The incidence of complications derived from this type of surgery has increased due to the greater number of patients undergoing dental rehabilitation ... ...

Abstract	The placement of dental implants is a safe and predictable procedure when performed by qualified staff. The incidence of complications derived from this type of surgery has increased due to the greater number of patients undergoing dental rehabilitation treatments in recent years. Floor of the mouth hematoma is a rare, but potentially fatal, complication that every oral surgeon should recognize for early diagnosis. As part of the clinical case presented here, two implants were removed and a hemorrhage in the floor of the mouth was found, which required an urgent intervention to control the bleeding. Two independent researchers conducted an electronic search of the available scientific evidence in relation to bleeding of the floor of the mouth in dental implant surgery. The research included references, which were written in English or Spanish, and published up to December 2022. Case reports, case series, systematic reviews, and meta-analysis were part of the inclusion criteria. Sixty-four bibliographic references were identified, and 39 full-text articles were selected. There were 30 cases of floor of the mouth hematoma in relation to implant surgery. In 13 patients the main location was interforaminal, in 5 in the canine area, in 6 in the incisor area, and in 6 in the molar premolar region. All cases were caused by perforation of the cortical bone or surgical manipulation (disruption of the periosteum, perforation of the sublingual mucosa by the stiff suture). The sublingual artery was most frequently involved. The clinical sign observed in all cases was elevation of the floor of the mouth. In 21 of the cases there was airway involvement, so the main treatment was intubation or tracheostomy. Floor of the mouth hematoma may be one complication associated with implant surgery. Given the seriousness of this clinical picture, early detection by the dentist and hospital referral are essential. Warning signs are sudden swelling of the floor of the mouth or submandibular area, accompanied by dysphagia and dyspnea.
Keywords	dental implant ; hematoma ; hemorrhage ; floor of mouth
Language	English
Publishing date	2024-02-18
Publisher	Thieme Medical and Scientific Publishers Pvt. Ltd.
Publishing place	Stuttgart ; New York
Document type	Article
ISSN	2791-7452
ISSN (online)	2791-7452
DOI	10.1055/s-0043-1776284
Database	Thieme publisher's database

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Article ; Online: "Management of recurrent temporomandibular dislocation using orthodontic traction screws."

Santás Alegret, Mario / Fernández García, Antonio / Gómez, Vicenç J / Olavarria Montes, Eduardo / Mejía Nieto, María / Sánchez Aniceto, Gregorio

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery

2021 Volume 49, Issue 11, Page(s) 1020–1025

Abstract: Temporomandibular joint dislocation is defined as the loss of joint congruency between the mandibular condyle and the glenoid fossa of the temporal bone. Multiple therapeutic options have been proposed for the treatment of recurrent TMJ dislocation. The ... ...

Abstract	Temporomandibular joint dislocation is defined as the loss of joint congruency between the mandibular condyle and the glenoid fossa of the temporal bone. Multiple therapeutic options have been proposed for the treatment of recurrent TMJ dislocation. The aim of this paper is to present two recently treated cases with a modification of Wolford's technique, replacing the Mitek anchors with orthodontic screws. Case series: The first case concerns a 36 year-old women with recurrent temporomandibular dislocation, and the second one a 26 year-old patient with the same diagnosis. In both cases, one 8mm orthodontic screw was placed in the lateral pole of mandibular condyle, sutured with PremiCron® 2/0 to a hole made in the root of each zygomatic arch. At twelve-month follow-up (first patient) and at six-month follow-up (second patient), patients had not presented new episodes of mandibular dislocation and mouth opening range remained stable. This technique can be considered as an alternative to Wolford's technique in treating recurrent temporomandibular dislocation when conservative management fails.
MeSH term(s)	Adult ; Bone Screws ; Female ; Humans ; Joint Dislocations/diagnostic imaging ; Joint Dislocations/surgery ; Mandibular Condyle/diagnostic imaging ; Mandibular Condyle/surgery ; Temporomandibular Joint ; Temporomandibular Joint Disorders/surgery ; Traction
Language	English
Publishing date	2021-06-22
Publishing country	Scotland
Document type	Case Reports
ZDB-ID	91267-0
ISSN	1878-4119 ; 1010-5182 ; 0301-0503
ISSN (online)	1878-4119
ISSN	1010-5182 ; 0301-0503
DOI	10.1016/j.jcms.2021.06.015
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Article: Dynamic Trends in Surgical Oromaxillofacial Trauma Epidemiology: A Comparative Study of Pre-COVID-19 and COVID-19 Periods in Tertiary Referral Hospitals in Madrid.

Sada-Urmeneta, Angela / Tousidonis, Manuel / Navarro-Cuellar, Carlos / Ochandiano, Santiago / Navarro-Cuellar, Ignacio / Khayat, Saad / Ruiz-de-León, Gonzalo / Benito-Anguita, Marta / Alvarez-Mokthari, Sara / Olavarria, Eduardo / Sanchez-Aniceto, Gregorio / Herrero-Alvarez, Sonia / de la Sen-Corcuera, Oscar / Simon-Flores, Anna-Maria / Almeida-Parra, Fernando / Aragon-Niño, Iñigo / Del-Castillo, Jose-Luis / Salmeron, Jose-Ignacio

Journal of clinical medicine

2024 Volume 13, Issue 7

Abstract: ... ...

Abstract	Introduction
Language	English
Publishing date	2024-03-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm13071947
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Article ; Online: A Novel Flap for Dynamic Reanimation of Facial Paralysis: Microvascular Sternohyoid Muscle Free Flap.

Santás Alegret, Mario / Fernández García, Antonio / Zafra Vallejo, Víctor / Rivero Calle, Álvaro / Sánchez Aniceto, Gregorio

Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

2020 Volume 79, Issue 4, Page(s) 925–931

Abstract: The main objectives of facial reanimation procedures include restoring facial symmetry at resting state and regaining facial mobility. Static procedures usually provide unsatisfactory results, especially in younger patients. For this reason, over the ... ...

Abstract	The main objectives of facial reanimation procedures include restoring facial symmetry at resting state and regaining facial mobility. Static procedures usually provide unsatisfactory results, especially in younger patients. For this reason, over the years, several different surgical alternatives based on autologous, locoregional, or muscle free flaps have been proposed. The gracilis muscle is the gold standard technique for dynamic reanimation of long-standing facial paralysis. The excessive muscle bulk and the differences regarding the type of predominant muscle fiber were compared with the zygomaticus major force reconstructive surgeons to search for alternatives to the gracilis as a potential free flap for reanimation. One of them is the sternohyoid muscle flap. We report a patient with long-standing facial paralysis who underwent a dynamic facial reanimation by using a sternohyoid muscle free flap, thus proposing the procedure as an alternative to the conventional gracilis muscle flap.
MeSH term(s)	Face ; Facial Muscles/surgery ; Facial Paralysis/surgery ; Free Tissue Flaps ; Humans ; Reconstructive Surgical Procedures
Language	English
Publishing date	2020-10-29
Publishing country	United States
Document type	Case Reports
ZDB-ID	392404-x
ISSN	1531-5053 ; 0278-2391
ISSN (online)	1531-5053
ISSN	0278-2391
DOI	10.1016/j.joms.2020.10.036
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Article: The Impact of Healthcare-Associated Infections in Patients Undergoing Oncological Microvascular Head and Neck Reconstruction: A Prospective Multicentre Study.

Ramos-Zayas, Ana / López-Medrano, Francisco / Urquiza-Fornovi, Irene / Zubillaga, Ignacio / Gutiérrez, Ramón / Sánchez-Aniceto, Gregorio / Acero, Julio / Almeida, Fernando / Galdona, Ana / Morán, María José / Pampin, Marta / Cebrián, José Luis

Cancers

2021 Volume 13, Issue 9

Abstract: 1) Background: Healthcare-associated infections (HAIs) after head and neck free-flap reconstruction are a common postoperative complication. Risk factors for HAIs in this context and their consequences have not been adequately described. (2) Methods: ... ...

Abstract	(1) Background: Healthcare-associated infections (HAIs) after head and neck free-flap reconstruction are a common postoperative complication. Risk factors for HAIs in this context and their consequences have not been adequately described. (2) Methods: Ongoing prospective multicentre study between 02/2019 and 12/2020. Demographic characteristics and outcomes were analysed, focusing on infections. (3) Results: Forty out of 65 patients (61.54%) suffered HAIs (surgical site infection: 52.18%, nosocomial pneumonia: 23.20%, bloodstream infection: 13% and urinary tract infection: 5.80%). Methicillin-resistant
Language	English
Publishing date	2021-04-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers13092109
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Article ; Online: Submandibular gland involvement in oral cavity squamous cell carcinoma: a retrospective multicenter study.

Iocca, Oreste / Copelli, Chiara / Garzino-Demo, Paolo / Ramieri, Guglielmo / Rubattino, Stefano / Sedran, Luca / Volpe, Fabio / Manfuso, Alfonso / Longo, Francesco / Sanchez-Aniceto, Gregorio / Rivero-Calle, Álvaro / García-Sánchez, Aitor / Pellini, Raul / Petruzzi, Gerardo / Moretto, Silvia / Al-Qamachi, Laith / Aga, Hiba / Ridley, Stephen / Di Maio, Pasquale

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

2023 Volume 280, Issue 9, Page(s) 4205–4214

Abstract: Background: The submandibular gland (SMG) is routinely excised during neck dissection. Given the importance of the SMG in saliva production, it is important to understand its involvement rate by cancer tissue and the feasibility of its preservation.: ... ...

Abstract	Background: The submandibular gland (SMG) is routinely excised during neck dissection. Given the importance of the SMG in saliva production, it is important to understand its involvement rate by cancer tissue and the feasibility of its preservation. Methods: Retrospective data were collected from five academic centers in Europe. The study involved adult patients affected by primary oral cavity carcinoma (OCC) undergoing tumor excision and neck dissection. The main outcome analyzed was the SMG involvement rate. A systematic review and a meta-analysis were also conducted to provide an updated synthesis of the topic. Results: A total of 642 patients were enrolled. The SMG involvement rate was 12/642 (1.9%; 95% CI 1.0-3.2) when considered per patient, and 12/852 (1.4%; 95% CI 0.6-2.1) when considered per gland. All the glands involved were ipsilateral to the tumor. Statistical analysis showed that predictive factors for gland invasion were: advanced pT status, advanced nodal involvement, presence of extracapsular spread and perivascular invasion. The involvement of level I lymph nodes was associated with gland invasion in 9 out of 12 cases. pN0 cases were correlated with a reduced risk of SMG involvement. The review of the literature and the meta-analysis confirmed the rare involvement of the SMG: on the 4458 patients and 5037 glands analyzed, the involvement rate was 1.8% (99% CI 1.1-2.7) and 1.6% (99% CI 1.0-2.4), respectively. Conclusions: The incidence of SMG involvement in primary OCC is rare. Therefore, exploring gland preservation as an option in selected cases would be reasonable. Future prospective studies are needed to investigate the oncological safety and the real impact on quality of life of SMG preservation.
MeSH term(s)	Adult ; Humans ; Squamous Cell Carcinoma of Head and Neck/pathology ; Submandibular Gland/surgery ; Retrospective Studies ; Quality of Life ; Mouth Neoplasms/surgery ; Mouth Neoplasms/pathology ; Carcinoma, Squamous Cell/surgery ; Carcinoma, Squamous Cell/pathology ; Neck Dissection ; Head and Neck Neoplasms/pathology ; Multicenter Studies as Topic
Language	English
Publishing date	2023-06-06
Publishing country	Germany
Document type	Systematic Review ; Meta-Analysis ; Journal Article
ZDB-ID	1017359-6
ISSN	1434-4726 ; 0937-4477
ISSN (online)	1434-4726
ISSN	0937-4477
DOI	10.1007/s00405-023-08007-8
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Article ; Online: Frontal sinus obliteration after trauma: analysis of bone regeneration for two selected methods.

Zubillaga Rodríguez, I / Lora Pablos, D / Falguera Uceda, M I / Díez Lobato, R / Sánchez Aniceto, G

International journal of oral and maxillofacial surgery

2014 Volume 43, Issue 7, Page(s) 827–833

Abstract: We present a prospective randomized experimental study comparing bone regeneration obtained in 60 post-traumatic frontal sinuses obliterated with either calvarial bone dust (n=30, group I) or calvarial bone and demineralized bone matrix (DBM; n=30, group ...

Abstract	We present a prospective randomized experimental study comparing bone regeneration obtained in 60 post-traumatic frontal sinuses obliterated with either calvarial bone dust (n=30, group I) or calvarial bone and demineralized bone matrix (DBM; n=30, group II). Radiological follow-up included high-resolution computed tomography with quantitative micro-density analysis in Hounsfield units (HU), together with a volumetric evaluation of the ossification at 6 and 24 months after surgical treatment. Epidemiological information and potential drawbacks were analysed. Bone volume and density data (HU) for the regenerated areas were subjected to statistical analysis at 6 and 24 months for both groups. Results were compared with reference values obtained from frontal and temporal bone in every patient. Complications developed for 10% of operated sinuses. The resulting bone formation (HU) in group I patients was significantly better than that obtained in group II. Ossification progressed in a statistically significant manner in both groups when compared at 6 and 24 months postoperatively. The use of DBM as a biomaterial associated with calvarial bone dust for sinus obliteration shows long-term safe results, similar to autogenous bone, but with a lower final bone density.
MeSH term(s)	Adolescent ; Adult ; Aged ; Biocompatible Materials ; Bone Density ; Bone Matrix/transplantation ; Bone Regeneration ; Bone Transplantation/methods ; Female ; Frontal Sinus/diagnostic imaging ; Frontal Sinus/injuries ; Frontal Sinus/surgery ; Humans ; Male ; Middle Aged ; Prospective Studies ; Tomography, X-Ray Computed
Chemical Substances	Biocompatible Materials
Language	English
Publishing date	2014-07
Publishing country	Denmark
Document type	Journal Article ; Randomized Controlled Trial
ZDB-ID	353721-3
ISSN	1399-0020 ; 0901-5027
ISSN (online)	1399-0020
ISSN	0901-5027
DOI	10.1016/j.ijom.2014.02.012
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