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  1. Article: Oxidative Decomposition of H2S over Alumina-Based Catalyst

    Palma, V / D. Barba / E. Palo / L. Barbato / M. Colozzi / S. Cortese / V. Vaiano

    Industrial & engineering chemistry process design and development. 2017 Aug. 16, v. 56, no. 32

    2017  

    Abstract: An Al2O3-based catalyst was employed for the first time in the H2S oxidative decomposition in order to obtain simultaneous sulfur and hydrogen. The influence of the reaction temperature (in the range of 700–1100 °C) and the contact time (in the range of ... ...

    Abstract An Al2O3-based catalyst was employed for the first time in the H2S oxidative decomposition in order to obtain simultaneous sulfur and hydrogen. The influence of the reaction temperature (in the range of 700–1100 °C) and the contact time (in the range of 17–33 ms) were investigated in terms of H2S conversion, H2 yield, and SO2 selectivity. Good catalytic performances were obtained at 1000 and 1100 °C with experimental values very close to those ones expected from the thermodynamic equilibrium. At a temperature of 1000 °C, the H2S conversion and H2 yield were, respectively, about 50% and 17%; in particular, the SO2 selectivity decreased of a magnitude order ∼0.5% with respect to the value observed in the homogeneous case (4%). A predictive mathematical model of H2S oxidative decomposition in the presence of a catalyst was developed through the identification of the main reactions occurring in the system. The results obtained from the kinetic investigations evidenced that the catalyst, in addition to the H2S decomposition reaction and the partial oxidation reaction to sulfur, was able also to promote the SO2 conversion by the Claus reaction allowing it to avoid the presence of SO2 at the reactor outlet.
    Keywords catalysts ; catalytic activity ; hydrogen ; hydrogen sulfide ; mathematical models ; oxidation ; process design ; sulfur ; sulfur dioxide ; temperature ; thermodynamics
    Language English
    Dates of publication 2017-0816
    Size p. 9072-9078.
    Publishing place American Chemical Society
    Document type Article
    ZDB-ID 1484436-9
    ISSN 1520-5045 ; 0888-5885
    ISSN (online) 1520-5045
    ISSN 0888-5885
    DOI 10.1021/acs.iecr.7b01960
    Database NAL-Catalogue (AGRICOLA)

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  2. Article: Virus detection by PCR following vaccination of naive calves with intranasal or injectable multivalent modified-live viral vaccines

    Walz, Paul H / Benjamin W. Newcomer / Kay P. Riddell / Daniel W. Scruggs / Victor S. Cortese

    Journal of veterinary diagnostic investigation. , v. 29, no. 5

    2017  

    Abstract: We evaluated duration of PCR-positive results following administration of modified-live viral (MLV) vaccines to beef calves. Twenty beef calves were randomly assigned to either group 1 and vaccinated intranasally with a MLV vaccine containing bovine ... ...

    Abstract We evaluated duration of PCR-positive results following administration of modified-live viral (MLV) vaccines to beef calves. Twenty beef calves were randomly assigned to either group 1 and vaccinated intranasally with a MLV vaccine containing bovine alphaherpesvirus 1 (BoHV-1), bovine respiratory syncytial virus (BRSV), and bovine parainfluenza virus 3 (BPIV-3), or to group 2 and vaccinated subcutaneously with a MLV vaccine containing bovine viral diarrhea virus 1 and 2 (BVDV-1, -2), BoHV-1, BRSV, and BPIV-3. Deep nasopharyngeal swabs (NPS) and transtracheal washes (TTW) were collected from all calves, and whole blood was collected from group 2 calves and tested by PCR. In group 1, the proportions of calves that tested PCR-positive to BVDV, BoHV-1, BRSV, and BPIV-3 on any sample at any time were 0%, 100%, 100%, and 10%, respectively. In group 1 calves, 100% of calves became PCR-positive for BoHV-1 by day 3 post-vaccination and 100% of calves became PCR-positive for BRSV by day 7 post-vaccination. In group 2, the proportions of calves that tested positive to BVDV, BoHV-1, BRSV, and BPIV-3 on any sample at any time were 50%, 40%, 10%, and 0%, respectively. All threshold cycle (Ct) values were >30 in group 2 calves, irrespective of virus; however, Ct values <25 were observed in group 1 calves from PCR-positive results for BoHV-1 and BRSV. All calves were PCR-negative for all viruses after day 28. Following intranasal MLV viral vaccination, PCR results and Ct values for BRSV and BoHV-1 suggest that attempts to differentiate vaccine virus from natural infection is unreliable.
    Keywords Bovine herpesvirus 1 ; Bovine orthopneumovirus ; Bovine parainfluenza virus 3 ; Bovine viral diarrhea virus 1 ; beef cattle ; blood ; calves ; polymerase chain reaction ; vaccination ; viral vaccines ; viruses ; covid19
    Language English
    Dates of publication 2017-09
    Size p. 628-635.
    Publishing place SAGE Publications
    Document type Article
    ZDB-ID 287603-6
    ISSN 1943-4936 ; 1040-6387
    ISSN (online) 1943-4936
    ISSN 1040-6387
    DOI 10.1177/1040638717709039
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3645: Show issues Location:
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  3. Article ; Online: Elucidation of functional markers from Aspergillus nidulans developmental regulator FlbB and their phylogenetic distribution.

    Marc S Cortese / Oier Etxebeste / Aitor Garzia / Eduardo A Espeso / Unai Ugalde

    PLoS ONE, Vol 6, Iss 3, p e

    2011  Volume 17505

    Abstract: Aspergillus nidulans is a filamentous fungus widely used as a model for biotechnological and clinical research. It is also used as a platform for the study of basic eukaryotic developmental processes. Previous studies identified and partially ... ...

    Abstract Aspergillus nidulans is a filamentous fungus widely used as a model for biotechnological and clinical research. It is also used as a platform for the study of basic eukaryotic developmental processes. Previous studies identified and partially characterized a set of proteins controlling cellular transformations in this ascomycete. Among these proteins, the bZip type transcription factor FlbB is a key regulator of reproduction, stress responses and cell-death. Our aim here was the prediction, through various bioinformatic methods, of key functional residues and motifs within FlbB in order to inform the design of future laboratory experiments and further the understanding of the molecular mechanisms that control fungal development. A dataset of FlbB orthologs and those of its key interaction partner FlbE was assembled from 40 members of the Pezizomycotina. Unique features were identified in each of the three structural domains of FlbB. The N-terminal region encoded a bZip transcription factor domain with a novel histidine-containing DNA binding motif while the dimerization determinants exhibited two distinct profiles that segregated by class. The C-terminal region of FlbB showed high similarity with the AP-1 family of stress response regulators but with variable patterns of conserved cysteines that segregated by class and order. Motif conservation analysis revealed that nine FlbB orthologs belonging to the Eurotiales order contained a motif in the central region that could mediate interaction with FlbE. The key residues and motifs identified here provide a basis for the design of follow-up experimental investigations. Additionally, the presence or absence of these residues and motifs among the FlbB orthologs could help explain the differences in the developmental programs among fungal species as well as define putative complementation groups that could serve to extend known functional characterizations to other species.
    Keywords Medicine ; R ; Science ; Q
    Subject code 572
    Language English
    Publishing date 2011-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article: A second component of the SltA-dependent cation tolerance pathway in Aspergillus nidulans

    Mellado, Laura / Ana Maria Calcagno-Pizarelli / Eduardo A. Espeso / Herbert N. Arst / Joan M. Kelly / Marc S. Cortese / Robin A. Lockington

    Fungal genetics and biology. 2015 Sept., v. 82

    2015  

    Abstract: The transcriptional response to alkali metal cation stress is mediated by the zinc finger transcription factor SltA in Aspergillus nidulans and probably in other fungi of the pezizomycotina subphylum. A second component of this pathway has been ... ...

    Abstract The transcriptional response to alkali metal cation stress is mediated by the zinc finger transcription factor SltA in Aspergillus nidulans and probably in other fungi of the pezizomycotina subphylum. A second component of this pathway has been identified and characterized. SltB is a 1272 amino acid protein with at least two putative functional domains, a pseudo-kinase and a serine-endoprotease, involved in signaling to the transcription factor SltA. Absence of SltB activity results in nearly identical phenotypes to those observed for a null sltA mutant. Hypersensitivity to a variety of monovalent and divalent cations, and to medium alkalinization are among the phenotypes exhibited by a null sltB mutant. Calcium homeostasis is an exception and this cation improves growth of sltΔ mutants. Moreover, loss of kinase HalA in conjunction with loss-of-function sltA or sltB mutations leads to pronounced calcium auxotrophy. sltA sltB double null mutants display a cation stress sensitive phenotype indistinguishable from that of single slt mutants showing the close functional relationship between these two proteins. This functional relationship is reinforced by the fact that numerous mutations in both slt loci can be isolated as suppressors of poor colonial growth resulting from certain null vps (vacuolar protein sorting) mutations. In addition to allowing identification of sltB, our sltB missense mutations enabled prediction of functional regions in the SltB protein. Although the relationship between the Slt and Vps pathways remains enigmatic, absence of SltB, like that of SltA, leads to vacuolar hypertrophy. Importantly, the phenotypes of selected sltA and sltB mutations demonstrate that suppression of null vps mutations is not dependent on the inability to tolerate cation stress. Thus a specific role for both SltA and SltB in the VPS pathway seems likely. Finally, it is noteworthy that SltA and SltB have a similar, limited phylogenetic distribution, being restricted to the pezizomycotina subphylum. The relevance of the Slt regulatory pathway to cell structure, intracellular trafficking and cation homeostasis and its restricted phylogenetic distribution makes this pathway of general interest for future investigation and as a source of targets for antifungal drugs.
    Keywords alkalinization ; amino acids ; antifungal agents ; Aspergillus nidulans ; calcium ; cations ; fungi ; homeostasis ; hypertrophy ; loci ; loss-of-function mutation ; missense mutation ; mutants ; Pandanus tectorius ; phenotype ; phylogeny ; prediction ; protein transport ; transcription (genetics) ; transcription factors ; vacuoles ; zinc finger motif
    Language English
    Dates of publication 2015-09
    Size p. 116-128.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 1319820-8
    ISSN 1096-0937 ; 1087-1845 ; 0147-5975
    ISSN (online) 1096-0937
    ISSN 1087-1845 ; 0147-5975
    DOI 10.1016/j.fgb.2015.06.002
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 79/730: Show issues

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  5. Article ; Online: GmcA is a putative glucose-methanol-choline oxidoreductase required for the induction of asexual development in Aspergillus nidulans.

    Oier Etxebeste / Erika Herrero-García / Marc S Cortese / Aitor Garzia / Elixabet Oiartzabal-Arano / Vivian de los Ríos / Unai Ugalde / Eduardo A Espeso

    PLoS ONE, Vol 7, Iss 7, p e

    2012  Volume 40292

    Abstract: Aspergillus nidulans asexual differentiation is induced by Upstream Developmental Activators (UDAs) that include the bZIP-type Transcription Factor (TF) FlbB. A 2D-PAGE/MS-MS-coupled screen for proteins differentially expressed in the presence and ... ...

    Abstract Aspergillus nidulans asexual differentiation is induced by Upstream Developmental Activators (UDAs) that include the bZIP-type Transcription Factor (TF) FlbB. A 2D-PAGE/MS-MS-coupled screen for proteins differentially expressed in the presence and absence of FlbB identified 18 candidates. Most candidates belong to GO term classes involved in osmotic and/or oxidative stress response. Among these, we focused on GmcA, a putative glucose-methanol-choline oxidoreductase which is upregulated in a ΔflbB background. GmcA is not required for growth since no differences were detected in the radial extension upon deletion of gmcA. However, its activity is required to induce conidiation under specific culture conditions. A ΔgmcA strain conidiates profusely under acid conditions but displays a characteristic fluffy aconidial phenotype in alkaline medium. The absence of asexual development in a ΔgmcA strain can be suppressed, on one hand, using high concentrations of non-fermentable carbon sources like glycerol, and on the other hand, when the cMyb-type UDA TF flbD is overexpressed. Overall, the results obtained in this work support a role for GmcA at early stages of conidiophore initiation.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2012-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Search for Gravitational Waves Associated with Gamma-Ray Bursts Detected by Fermi and Swift During the LIGO-Virgo Run O3a

    Collaboration, The LIGO Scientific / R.Abbott, the Virgo Collaboration / T.D.Abbott, / S.Abraham, / F.Acernese, / K.Ackley, / C.Adams, / R.X.Adhikari, / V.B.Adya, / C.Affeldt, / M.Agathos, / K.Agatsuma, / N.Aggarwal, / O.D.Aguiar, / A.Aich, / L.Aiello, / A.Ain, / P.Ajith, / G.Allen, /
    A.Allocca, / P.A.Altin, / A.Amato, / S.Anand, / A.Ananyeva, / S.B.Anderson, / W.G.Anderson, / S.V.Angelova, / S.Ansoldi, / S.Antier, / S.Appert, / K.Arai, / M.C.Araya, / J.S.Areeda, / M.Arene, / N.Arnaud, / S.M.Aronson, / Y.Asali, / S.Ascenzi, / G.Ashton, / M.Assiduo, / S.M.Aston, / P.Astone, / F.Aubin, / P.Aufmuth, / K.AultONeal, / C.Austin, / V.Avendano, / S.Babak, / P.Bacon, / F.Badaracco, / M.K.M.Bader, / S.Bae, / A.M.Baer, / J.Baird, / F.Baldaccini, / G.Ballardin, / S.W.Ballmer, / A.Bals, / A.Balsamo, / G.Baltus, / S.Banagiri, / D.Bankar, / R.S.Bankar, / J.C.Barayoga, / C.Barbieri, / B.C.Barish, / D.Barker, / K.Barkett, / P.Barneo, / F.Barone, / B.Barr, / L.Barsotti, / M.Barsuglia, / D.Barta, / J.Bartlett, / I.Bartos, / R.Bassiri, / A.Basti, / M.Bawaj, / J.C.Bayley, / M.Bazzan, / B.B'ecsy, / M.Bejger, / I.Belahcene, / A.S.Bell, / D.Beniwal, / M.G.Benjamin, / J.D.Bentley, / F.Bergamin, / B.K.Berger, / G.Bergmann, / S.Bernuzzi, / C.P.L.Berry, / D.Bersanetti, / A.Bertolini, / J.Betzwieser, / R.Bhandare, / A.V.Bhandari, / A.Bianchi, / J.Bidler, / E.Biggs, / I.A.Bilenko, / G.Billingsley, / R.Birney, / O.Birnholtz, / S.Biscans, / M.Bischi, / S.Biscoveanu, / A.Bisht, / G.Bissenbayeva, / M.Bitossi, / M.A.Bizouard, / J.K.Blackburn, / J.Blackman, / C.D.Blair, / D.G.Blair, / R.M.Blair, / F.Bobba, / N.Bode, / M.Boer, / Y.Boetzel, / G.Bogaert, / F.Bondu, / E.Bonilla, / R.Bonnand, / P.Booker, / B.A.Boom, / R.Bork, / V.Boschi, / S.Bose, / V.Bossilkov, / J.Bosveld, / Y.Bouffanais, / A.Bozzi, / C.Bradaschia, / P.R.Brady, / A.Bramley, / M.Branchesi, / J.E.Brau, / M.Breschi, / T.Briant, / J.H.Briggs, / F.Brighenti, / A.Brillet, / M.Brinkmann, / P.Brockill, / A.F.Brooks, / J.Brooks, / D.D.Brown, / S.Brunett, / G.Bruno, / R.Bruntz, / A.Buikema, / T.Bulik, / H.J.Bulten, / A.Buonanno, / D.Buskulic, / R.L.Byer, / M.Cabero, / L.Cadonati, / G.Cagnoli, / C.Cahillane, / Bustillo, J.Calder'on / J.D.Callaghan, / T.A.Callister, / E.Calloni, / J.B.Camp, / M.Canepa, / Santoro, G.Caneva / K.C.Cannon, / H.Cao, / J.Cao, / G.Carapella, / F.Carbognani, / S.Caride, / M.F.Carney, / G.Carullo, / T.L.Carver, / Diaz, J.Casanueva / C.Casentini, / J.Castaneda, / S.Caudill, / M.Cavaglia, / F.Cavalier, / R.Cavalieri, / G.Cella, / P.Cerd'a-Dur'an, / E.Cesarini, / O.Chaibi, / K.Chakravarti, / C.Chan, / M.Chan, / S.Chao, / P.Charlton, / E.A.Chase, / E.Chassande-Mottin, / D.Chatterjee, / M.Chaturvedi, / H.Y.Chen, / X.Chen, / Y.Chen, / H.-P.Cheng, / C.K.Cheong, / H.Y.Chia, / F.Chiadini, / R.Chierici, / A.Chincarini, / A.Chiummo, / G.Cho, / H.S.Cho, / M.Cho, / N.Christensen, / Q.Chu, / S.Chua, / K.W.Chung, / S.Chung, / G.Ciani, / P.Ciecielag, / M.Cie'slar, / A.A.Ciobanu, / R.Ciolfi, / F.Cipriano, / A.Cirone, / F.Clara, / J.A.Clark, / P.Clearwater, / S.Clesse, / F.Cleva, / E.Coccia, / P.-F.Cohadon, / D.Cohen, / M.Colleoni, / C.G.Collette, / C.Collins, / M.Colpi, / M.Constancio, / L.Conti, / S.J.Cooper, / P.Corban, / T.R.Corbitt, / I.Cordero-Carri'on, / S.Corezzi, / K.R.Corley, / N.Cornish, / D.Corre, / A.Corsi, / S.Cortese, / C.A.Costa, / R.Cotesta, / M.W.Coughlin, / S.B.Coughlin, / J.-P.Coulon, / S.T.Countryman, / P.Couvares, / P.B.Covas, / D.M.Coward, / M.J.Cowart, / D.C.Coyne, / R.Coyne, / J.D.E.Creighton, / T.D.Creighton, / J.Cripe, / M.Croquette, / S.G.Crowder, / J.-R.Cudell, / T.J.Cullen, / A.Cumming, / R.Cummings, / L.Cunningham, / E.Cuoco, / M.Curylo, / Canton, T.Dal / G.D'alya, / A.Dana, / L.M.Daneshgaran-Bajastani, / B.D'Angelo, / S.L.Danilishin, / S.D'Antonio, / K.Danzmann, / C.Darsow-Fromm, / A.Dasgupta, / L.E.H.Datrier, / V.Dattilo, / I.Dave, / M.Davier, / G.S.Davies, / D.Davis, / E.J.Daw, / D.DeBra, / M.Deenadayalan, / J.Degallaix, / Laurentis, M.De / S.Del'eglise, / M.Delfavero, / Lillo, N.De / Pozzo, W.Del / L.M.DeMarchi, / V.D'Emilio, / N.Demos, / T.Dent, / Pietri, R.De / Rosa, R.De / Rossi, C.De / R.DeSalvo, / Varona, O.de / S.Dhurandhar, / M.C.D'iaz, / M.Diaz-Ortiz, / T.Dietrich, / Fiore, L.Di / Fronzo, C.Di / Giorgio, C.Di / Giovanni, F.Di / Giovanni, M.Di / Girolamo, T.Di / Lieto, A.Di / B.Ding, / Pace, S.Di / Palma, I.Di / Renzo, F.Di / A.K.Divakarla, / A.Dmitriev, / Z.Doctor, / F.Donovan, / K.L.Dooley, / S.Doravari, / I.Dorrington, / T.P.Downes, / M.Drago, / J.C.Driggers, / Z.Du, / J.-G.Ducoin, / P.Dupej, / O.Durante, / D.D'Urso, / S.E.Dwyer, / P.J.Easter, / G.Eddolls, / B.Edelman, / T.B.Edo, / O.Edy, / A.Effler, / P.Ehrens, / J.Eichholz, / S.S.Eikenberry, / M.Eisenmann, / R.A.Eisenstein, / A.Ejlli, / L.Errico, / R.C.Essick, / H.Estelles, / D.Estevez, / Z.B.Etienne, / T.Etzel, / M.Evans, / T.M.Evans, / B.E.Ewing, / V.Fafone, / S.Fairhurst, / X.Fan, / S.Farinon, / B.Farr, / W.M.Farr, / E.J.Fauchon-Jones, / M.Favata, / M.Fays, / M.Fazio, / J.Feicht, / M.M.Fejer, / F.Feng, / E.Fenyvesi, / D.L.Ferguson, / A.Fernandez-Galiana, / I.Ferrante, / E.C.Ferreira, / T.A.Ferreira, / F.Fidecaro, / I.Fiori, / D.Fiorucci, / M.Fishbach, / R.P.Fisher, / R.Fittipaldi, / M.Fitz-Axen, / V.Fiumara, / R.Flaminio, / E.Floden, / E.Flynn, / 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    Abstract: We search for gravitational-wave transients associated with gamma-ray bursts detected by the Fermi and Swift satellites during the first part of the third observing run of Advanced LIGO and Advanced Virgo (1 April 2019 15:00 UTC - 1 October 2019 15:00 ... ...

    Abstract We search for gravitational-wave transients associated with gamma-ray bursts detected by the Fermi and Swift satellites during the first part of the third observing run of Advanced LIGO and Advanced Virgo (1 April 2019 15:00 UTC - 1 October 2019 15:00 UTC). 105 gamma-ray bursts were analyzed using a search for generic gravitational-wave transients; 32 gamma-ray bursts were analyzed with a search that specifically targets neutron star binary mergers as short gamma-ray burst progenitors. We describe a method to calculate the probability that triggers from the binary merger targeted search are astrophysical and apply that method to the most significant gamma-ray bursts in that search. We find no significant evidence for gravitational-wave signals associated with the gamma-ray bursts that we followed up, nor for a population of unidentified subthreshold signals. We consider several source types and signal morphologies, and report for these lower bounds on the distance to each gamma-ray burst.
    Keywords covid19
    Publisher ArXiv
    Document type Article
    Database COVID19

    Kategorien

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