Result 1 - 10 of total 10
2. Eifel Workshop (Göttingen 2001)
2001
| Publishing country | de |
|---|---|
| Document type | Conference proceedings ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
Geophysical Journal International
indications for the Eifel plume
2001
Abstract: The topographies of the upper mantle discontinuities at 410 and 660 km depth under Central Europe have been mapped. Using a modified receiver function approach, we processed data recorded at selected Central European broadband stations during the years ... ...
| Abstract | The topographies of the upper mantle discontinuities at 410 and 660 km depth under Central Europe have been mapped. Using a modified receiver function approach, we processed data recorded at selected Central European broadband stations during the years 1981-1998. Below the Rhenish massif near the Eifel region we identified a significantly deepened 410 discontinuity that may have its origin in an upgoing mantle plume, in agreement with recently derived results from seismic tomography. We have furthermore found evidence for a northwarddipping structure at the lower boundary of the mantle transition zone below the Alps, possibly related to the subduction that occurred during the closing of the Tethys. |
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| Publishing country | de |
| Document type | Article ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
61. Jahrestagung der Deutschen Geophysikalischen Gesellschaft (Frankfurt/Main 2001)
2001
| Publishing country | de |
|---|---|
| Document type | Conference proceedings ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
2. Eifel Workshop (Göttingen 2001)
2000
| Publishing country | de |
|---|---|
| Document type | Conference proceedings ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
Orphanet Journal of Rare Diseases, Vol 14, Iss 1, Pp 1-
lessons from the GalNet registry
2019 Volume 11
Abstract: Abstract Background Classic galactosemia is a rare inborn error of carbohydrate metabolism, caused by a severe deficiency of the enzyme galactose-1-phosphate uridylyltransferase (GALT). A galactose-restricted diet has proven to be very effective to treat ...
| Abstract | Abstract Background Classic galactosemia is a rare inborn error of carbohydrate metabolism, caused by a severe deficiency of the enzyme galactose-1-phosphate uridylyltransferase (GALT). A galactose-restricted diet has proven to be very effective to treat the neonatal life-threatening manifestations and has been the cornerstone of treatment for this severe disease. However, burdensome complications occur despite a lifelong diet. For rare diseases, a patient disease specific registry is fundamental to monitor the lifespan pathology and to evaluate the safety and efficacy of potential therapies. In 2014, the international Galactosemias Network (GalNet) developed a web-based patient registry for this disease, the GalNet Registry. The aim was to delineate the natural history of classic galactosemia based on a large dataset of patients. Methods Observational data derived from 15 countries and 32 centers including 509 patients were acquired between December 2014 and July 2018. Results Most affected patients experienced neonatal manifestations (79.8%) and despite following a diet developed brain impairments (85.0%), primary ovarian insufficiency (79.7%) and a diminished bone mineral density (26.5%). Newborn screening, age at onset of dietary treatment, strictness of the galactose-restricted diet, p.Gln188Arg mutation and GALT enzyme activity influenced the clinical picture. Detection by newborn screening and commencement of diet in the first week of life were associated with a more favorable outcome. A homozygous p.Gln188Arg mutation, GALT enzyme activity of ≤ 1% and strict galactose restriction were associated with a less favorable outcome. Conclusion This study describes the natural history of classic galactosemia based on the hitherto largest data set. |
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| Keywords | Registry ; Natural history ; Galactosemia ; GALT deficiency ; Galactosemia network ; Medicine ; R |
| Subject code | 616 |
| Language | English |
| Publishing date | 2019-04-01T00:00:00Z |
| Publisher | BMC |
| Document type | Article ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
Journal of South American Earth Sciences
1999
Abstract: In this study, we present an interpretation of seismic refraction profiles from the PISCO 94 experiment in northern Chile. As the PISCO experiment was a combined active and passive seismological study, we also discuss results of the passive part in the ... ...
| Abstract | In this study, we present an interpretation of seismic refraction profiles from the PISCO 94 experiment in northern Chile. As the PISCO experiment was a combined active and passive seismological study, we also discuss results of the passive part in the context of the seismic refraction model. Previous seismic refraction and gravimetric studies indicate a maximum crustal thickness of about 70 km beneath the Pre- and Western Cordillera. The new seismic refraction data lead to a differentiated image of the Andean crust which shows strong varying characteristics. The crustal discontinuities (up to five are detected) dip from W to E. The upper crust has a thickness of 18 km (Precordillera) to 23 km (magmatic arc) underlain by the recent middle crust down to 35-45 km where the velocity increases to about 7 km/s at its base. This crustal level is interpreted as old continental lower crust and its base as blurred continental (paleo) Moho. Beneath the Precordillera, a strong discontinuity at 70 km depth with a velocity increase to about 8 km/s was detected, interpreted as the recent geophysical Moho. For the magmatic arc, this deep discontinuity could not be found by active seismic measurements. The tomographic models of the seismological studies, in general, confirm the seismic refraction results. Anomalously high vp/vs rations in the deeper part of the forearc indicate a hydrated mantle wedge consisting of serpentine and amphibole-bearing peridotite and the 70 km discontinuity is interpreted as the boundary between these two different stages of the hydrated mantle wedge. A zone of high attenuation (Qp) and high vp/vs ratios beneath the magmatic arc coincides with the low velocity zones and indicates partially molten rocks from a depth of 20 km down to the asthenospheric wedge. |
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| Subject code | 550 |
| Publishing country | de |
| Document type | Article ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
Nature
1999
| Publishing country | de |
|---|---|
| Document type | Article ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
Geophysical Journal International
2004
Abstract: To address one of the central questions of plate tectonics - How do large transform systems work and what are their typical features? - seismic investigations across the Dead Sea Transform (DST), the boundary between the African and Arabian plates in the ...
| Abstract | To address one of the central questions of plate tectonics - How do large transform systems work and what are their typical features? - seismic investigations across the Dead Sea Transform (DST), the boundary between the African and Arabian plates in the Middle East, were conducted for the first time. A major component of these investigations was a combined reflection/refraction survey across the territories of Palestine, Israel and Jordan. The main results of this study are: (1) The seismic basement is offset by 3-5 km under the DST, (2) The DST cuts through the entire crust, broadening in the lower crust, (3) Strong lower crustal reflectors are imaged only on one side of the DST, (4) The seismic velocity sections show a steady increase in the depth of the crust-mantle transition (Moho) from ~26 km at the Mediterranean to ~39 km under the Jordan highlands, with only a small but visible, asymmetric topography of the Moho under the DST. These observations con be linked to the left-lateral movement of 105 km of the two plates in the last 17 Myr, accompanied by strong deformation within a narrow zone cutting through the entire crust. Comparing the DST and the San Andreas Fault (SAF) system, a strong asymmetry in subhorizontal lower crustal reflectors and a deep reaching deformation zone both occur around the DST and the SAF. The fact that such lower crustal reflectors and deep deformation zones are observed in such different transfrom plate boundaries. |
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| Subject code | 550 |
| Publishing country | de |
| Document type | Article ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
ORFEUS Newsletter
2002
| Publishing country | de |
|---|---|
| Document type | Article ; Online |
| Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.
Abstract: We search for gravitational-wave transients associated with gamma-ray bursts detected by the Fermi and Swift satellites during the first part of the third observing run of Advanced LIGO and Advanced Virgo (1 April 2019 15:00 UTC - 1 October 2019 15:00 ... ...
| Abstract | We search for gravitational-wave transients associated with gamma-ray bursts detected by the Fermi and Swift satellites during the first part of the third observing run of Advanced LIGO and Advanced Virgo (1 April 2019 15:00 UTC - 1 October 2019 15:00 UTC). 105 gamma-ray bursts were analyzed using a search for generic gravitational-wave transients; 32 gamma-ray bursts were analyzed with a search that specifically targets neutron star binary mergers as short gamma-ray burst progenitors. We describe a method to calculate the probability that triggers from the binary merger targeted search are astrophysical and apply that method to the most significant gamma-ray bursts in that search. We find no significant evidence for gravitational-wave signals associated with the gamma-ray bursts that we followed up, nor for a population of unidentified subthreshold signals. We consider several source types and signal morphologies, and report for these lower bounds on the distance to each gamma-ray burst. |
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| Keywords | covid19 |
| Publisher | ArXiv |
| Document type | Article |
| Database | COVID19 |
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.