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  1. Article ; Online: Double ring sign as a specific dermoscopic feature of lichen planopilaris: Toward a deeper understanding of disease.

    Saber, Mina / Naeini, Farahnaz Fatemi

    Journal of cosmetic dermatology

    2023  Volume 22, Issue 7, Page(s) 2122–2125

    MeSH term(s) Humans ; Lichen Planus/diagnostic imaging ; Alopecia
    Language English
    Publishing date 2023-01-30
    Publishing country England
    Document type Letter
    ZDB-ID 2280551-5
    ISSN 1473-2165 ; 1473-2130
    ISSN (online) 1473-2165
    ISSN 1473-2130
    DOI 10.1111/jocd.15663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Scalp capillarectasia as a trichoscopic sign of COVID-19-associated telogen effluvium.

    Saber, Mina / Mardani, Elahe / Shahmoradi, Zabihollah

    Journal of cosmetic dermatology

    2023  Volume 22, Issue 8, Page(s) 2372–2373

    MeSH term(s) Humans ; Scalp/diagnostic imaging ; COVID-19 ; Alopecia Areata
    Language English
    Publishing date 2023-03-09
    Publishing country England
    Document type Letter
    ZDB-ID 2280551-5
    ISSN 1473-2165 ; 1473-2130
    ISSN (online) 1473-2165
    ISSN 1473-2130
    DOI 10.1111/jocd.15717
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Disseminated perforating necrobiosis lipoidica: A case report and literature review.

    Saber, Mina / Mohaghegh, Fatemeh / Mohammadian, Parisa

    Clinical case reports

    2023  Volume 11, Issue 10, Page(s) e7991

    Abstract: Key clinical message: Necrobiosis lipoidica is a rare cutaneous granulomatous disease that mainly affects diabetic patients. The perforating type of the disease is an uncommon variant that is resistant to therapy and can be easily identified using ... ...

    Abstract Key clinical message: Necrobiosis lipoidica is a rare cutaneous granulomatous disease that mainly affects diabetic patients. The perforating type of the disease is an uncommon variant that is resistant to therapy and can be easily identified using dermoscopy.
    Abstract: Perforating necrobiosis lipoidica (NL) is a rare NL variant that primarily affects patients with diabetes mellitus (DM). Dermoscopy helps to differentiate this type of disease. The disseminated form of perforating NL mainly occurs in the setting of DM. Here we present a case of disseminated perforating NL in a 24-year-old woman with type 1 DM.
    Language English
    Publishing date 2023-10-03
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.7991
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Clinical efficacy and safety of low-dose oral minoxidil versus topical solution in the improvement of androgenetic alopecia: A randomized controlled trial.

    Asilian, Ali / Farmani, Aida / Saber, Mina

    Journal of cosmetic dermatology

    2023  Volume 23, Issue 3, Page(s) 949–957

    Abstract: Background: Topical minoxidil is the recommended first-line pharmacologic treatment for male and female pattern hair loss. However, low-dose oral minoxidil has been used off-label with good clinical efficacy and safety.: Aim: To compare the ... ...

    Abstract Background: Topical minoxidil is the recommended first-line pharmacologic treatment for male and female pattern hair loss. However, low-dose oral minoxidil has been used off-label with good clinical efficacy and safety.
    Aim: To compare the effectiveness and safety of topical minoxidil as a first-choice treatment of androgenetic alopecia versus 1 mg daily oral minoxidil.
    Method: Sixty-five AGA patients were randomly allocated to receive either 5% topical solution or 1 mg/day oral minoxidil for 6 months. Treatment efficacy was evaluated by measuring hair diameter, photographic assessment, and patient self-assessment questionnaires. The safety of treatment was checked through history taking and physical examination.
    Results: Both topical and oral minoxidil groups showed significant improvement in hair diameter after 6 months of treatment (p < 0.001). However, there was no significant difference between the two groups. The photographic assessment demonstrated a significant improvement in hair density in the topical minoxidil group in all marked points located at 12 cm (p = 0.025), 16 cm (p = 0.034), and 24 cm (p = 0.014) distance from the glabella but not in the oral minoxidil group. Nevertheless, the difference between the two groups was not significant. In each group, over 60% of patients expressed satisfaction with their treatments, and no significant difference was detected between the two groups.
    Conclusion: Although topical minoxidil has a better overall therapeutic effect than 1 mg oral minoxidil, the difference between the two groups was not significant. Therefore, 1 mg oral minoxidil may be as effective and safe as standard topical minoxidil in female and male pattern hair loss.
    MeSH term(s) Humans ; Female ; Male ; Minoxidil/adverse effects ; Alopecia/diagnosis ; Alopecia/drug therapy ; Treatment Outcome ; Hair ; Photography
    Chemical Substances Minoxidil (5965120SH1)
    Language English
    Publishing date 2023-11-29
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2280551-5
    ISSN 1473-2165 ; 1473-2130
    ISSN (online) 1473-2165
    ISSN 1473-2130
    DOI 10.1111/jocd.16086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Q-switched frequency-doubled Nd:YAG (532 nm) laser versus trichloroacetic acid 35% peeling in the treatment of dorsal hand solar lentigo: An assessor-blind split-hand randomized controlled trial.

    Iraji, Fariba / Mousavi, Azam / Poostiyan, Nazila / Saber, Mina

    Journal of cosmetic dermatology

    2022  

    Abstract: Background: Solar lentigo (SL) is a benign hyperpigmented spot occurring due to ultraviolet exposure, most commonly in the elderly. We aimed to compare the safety and efficacy of trichloroacetic acid (TCA) peeling with Q-switched laser in the treatment ... ...

    Abstract Background: Solar lentigo (SL) is a benign hyperpigmented spot occurring due to ultraviolet exposure, most commonly in the elderly. We aimed to compare the safety and efficacy of trichloroacetic acid (TCA) peeling with Q-switched laser in the treatment of SLs.
    Methods: This assessor-blind split-hand randomized controlled trial included 45 patients with symmetric SLs on the back of their hands referred to the dermatology clinics from March 1 to June 24, 2021. TCA 35% was applied to the back of one hand, and the contralateral hand received Q-switched laser. The interventions were repeated for a total of three sessions 4 weeks apart. Eight weeks after the last treatment session, lesion lightening was graded from 1 to 4. Patient satisfaction with treatment was assessed using a visual analogue scale (VAS). Adverse events were also noted.
    Results: Of the 45 patients included in the current study with a mean age of 52.71 ± 9.73 years, 11 (24.4%) were male. The Fitzpatrick skin type was II in 11 patients (24.4%), III in 23 (51.1%), and IV in 11 (24.4%). Lesion lightening and patient satisfaction were both significantly better with Q-switched laser compared to TCA peeling (standardized mean difference [SMD] = -1.25, 95% confidence interval [CI] -1.69; -0.79, p < 0.001 and SMD = -1.12, 95% CI -1.56; -0.67, p < 0.001, respectively). Overall, post-inflammatory hyperpigmentation (PIH) occurred in one patient in the laser group and for in the TCA group. Also, erythema and pruritus were observed in all patients of both groups after intervention which were treated with topical repair cream.
    Conclusions: Q-switched laser was superior to TCA peeling for the treatment of SLs in terms of lesion lightening and patient satisfaction with a large effect.
    Language English
    Publishing date 2022-09-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2280551-5
    ISSN 1473-2165 ; 1473-2130
    ISSN (online) 1473-2165
    ISSN 1473-2130
    DOI 10.1111/jocd.15385
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Generalized granuloma annulare in a case of breast cancer: A case report and review of the literature.

    Saber, Mina / Khalili Tembi, Roghaye Sadat / Asilian, Ali

    Clinical case reports

    2021  Volume 9, Issue 10, Page(s) e04980

    Abstract: Generalized granuloma annulare can be associated with breast cancer. Atypical granuloma annulare especially in older patients should alert physicians to the possibility of an occult malignancy. ...

    Abstract Generalized granuloma annulare can be associated with breast cancer. Atypical granuloma annulare especially in older patients should alert physicians to the possibility of an occult malignancy.
    Language English
    Publishing date 2021-10-18
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.4980
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Lichen planopilaris: A review of evaluation methods.

    Naeini, Farahnaz Fatemi / Saber, Mina / Faghihi, Gita

    Indian journal of dermatology, venereology and leprology

    2021  Volume 87, Issue 3, Page(s) 442–445

    MeSH term(s) Alopecia/etiology ; Humans ; Lichen Planus/complications ; Lichen Planus/diagnosis ; Scalp Dermatoses/diagnosis ; Scalp Dermatoses/etiology
    Language English
    Publishing date 2021-04-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 416068-x
    ISSN 0973-3922 ; 0019-5162 ; 0378-6323
    ISSN (online) 0973-3922
    ISSN 0019-5162 ; 0378-6323
    DOI 10.25259/IJDVL_775_18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: "Follicular prominency", a new clinical sign in lichen planopilaris: Fire under the ashes.

    Fatemi Naeini, Farahnaz / Saber, Mina / Mohaghegh, Fatemeh

    Dermatologic therapy

    2021  Volume 34, Issue 2, Page(s) e14873

    MeSH term(s) Alopecia ; Humans ; Lichen Planus/diagnosis
    Language English
    Publishing date 2021-02-21
    Publishing country United States
    Document type Letter
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14873
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  9. Article: Comparative Efficacy Study Combination of Oral Methotrexate and Prednisolone versus Oral Methotrexate in Patients with Lichen Planopilaris.

    Fatemi, Farahnaz / Esfahanian, Farifteh / Asilian, Ali / Mohaghegh, Fatemeh / Saber, Mina

    Dermatology research and practice

    2022  Volume 2022, Page(s) 3792489

    Abstract: Background: Lichen planopilaris (LPP) is a rare inflammatory disorder of the scalp that causes cicatricial alopecia. No therapeutic approach has been approved for this disease due to the rare frequency. Methotrexate and corticosteroid are commonly ... ...

    Abstract Background: Lichen planopilaris (LPP) is a rare inflammatory disorder of the scalp that causes cicatricial alopecia. No therapeutic approach has been approved for this disease due to the rare frequency. Methotrexate and corticosteroid are commonly considered second- or third-line therapy. The efficacy of a combination of methotrexate and corticosteroid has been reported in some dermatological and immunological diseases. However, the efficacy of this combination in LPP is not clear. Therefore, this study aimed to compare the impact of methotrexate alone and in combination with corticosteroid on LPP.
    Materials and methods: This randomized clinical trial was performed on 28 patients who referred to the dermatology clinic affiliated with Isfahan University of Medical Sciences, Isfahan, Iran during February 2015-December 2016, and 24 of them completed the trials. Fourteen patients received 15 mg methotrexate per week alone and the other fourteen subjects received 200 mg prednisolone plus 15 mg methotrexate per week. The primary outcome was Lichen planopilaris activity index (LPPAI) score. Moreover, we evaluated photographic changes and symptoms during the study.
    Results: The mean of LPPAI in both groups decreased during the follow-up with a similar pattern of LPPAI changes in both groups. No statistically significant difference was found between the two intervention groups regarding the LPPAI score. We found no difference in the symptoms and photographic assessments in methotrexate and combination therapy groups during follow-up. In both groups, exclusively one adverse effect was reported.
    Conclusions: Our results showed that methotrexate therapy with and without corticosteroids had similar efficacy and safety.
    Language English
    Publishing date 2022-10-08
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2548952-5
    ISSN 1687-6113 ; 1687-6105
    ISSN (online) 1687-6113
    ISSN 1687-6105
    DOI 10.1155/2022/3792489
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Granuloma annulare with alopecia areata in a 6-year-old girl: a case report.

    Mohaghegh, Fatemeh / Moeine, Reza / Saber, Mina / Fatemeh, Safdarian / Nekooeian, Mohammad / Shahriarirad, Reza

    Journal of medical case reports

    2023  Volume 17, Issue 1, Page(s) 192

    Abstract: Background: Dermatologic signs and symptoms can be the manifestations of a single disease or different diseases, and it is proven that some are associated with one another. These connections are not fully understood, but the answer lies in the ... ...

    Abstract Background: Dermatologic signs and symptoms can be the manifestations of a single disease or different diseases, and it is proven that some are associated with one another. These connections are not fully understood, but the answer lies in the pathophysiology of each disease.
    Case presentation: We report the case of a 6-year-old Middle-Eastern girl who presented with two skin lesions on the dorsum of her foot, along with scaling of her soles and palms, face skin discoloration, and areas of patchy alopecia on her scalp. She was diagnosed as a case of acute onset of granuloma annulare with alopecia areata and dermatitis. The treatment regimen for the patient's scalp consisted of topical minoxidil and betamethasone and three sessions with 1-month intervals of triamcinolone acetonide intralesional injections, which demonstrated modest effectiveness in treating alopecia areata.
    Conclusion: Granuloma annulare is a benign inflammatory illness with no known cause that might be difficult to cure. The clinical course and prognosis might vary greatly depending on the disease subtype, and associating symptoms and diseases, such as alopecia areata, should be considered.
    MeSH term(s) Female ; Humans ; Child ; Alopecia Areata/complications ; Alopecia Areata/drug therapy ; Granuloma Annulare/complications ; Granuloma Annulare/drug therapy ; Granuloma Annulare/pathology ; Glucocorticoids/therapeutic use ; Scalp/pathology
    Chemical Substances Glucocorticoids
    Language English
    Publishing date 2023-05-11
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-023-03864-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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