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  1. Article ; Online: SEXUAL BEHAVIOURS AND HUMAN PAPILLOMAVIRUS GENOTYPING AMONG BOSNIAN WOMEN

    Sabina Mahmutovic-Vranic

    Journal of IMAB, Vol 26, Iss 1, Pp 2898-

    2020  Volume 2904

    Abstract: Purpose: Youth represents the most vulnerable population, mainly due to their lifestyle derived from risky sexual behaviours. The aim of the study was to identify specific HPV genotypes correlating with cervical smear cytologic abnormalities, well as ... ...

    Abstract Purpose: Youth represents the most vulnerable population, mainly due to their lifestyle derived from risky sexual behaviours. The aim of the study was to identify specific HPV genotypes correlating with cervical smear cytologic abnormalities, well as sociodemographic/behavioural characteristics and history of sexually transmitted diseases in Bosnian women age up to 30 years. Methods: The longitudinal study was performed at the Department of Microbiology School of Medicine University of Sarajevo and Institute for Public Health dr. Andrija Stampar, Zagreb, Croatia from June 2017 to January 2018. Thirty (30) cervical smears were taken from tested females were screened using COBAS assay for HPV DNA testing. Routine Pap screening was performed in the Public Institution Department for Health Care of Women and Maternity of Sarajevo Canton. A self-administered questionnaire was applied. Results: A total of 30 sexually active women with abnormal cytological reports were enrolled in the study. The mean age was 26 IQR (20.75, 29.0) year. The overall prevalence of HR HPV was 66.7 %. Women age of ≤25 years had a positive association with positive results of HPV testing, OR=1.91. Consummation of alcohol, cigarettes had a strong positive association with positive HPV testing. Conclusions: The data obtained from this study indicate that HPV 16 is the most common HPV type found in the cervical specimens among young Bosnian women, followed by HPV 18. HPV DNA testing using as a screening test should be considered in the development of cervical cancer prevention programs in Bosnia and Herzegovina.
    Keywords sexual behaviour ; human papillomavirus ; risk factors ; condom ; Dentistry ; RK1-715 ; Medicine (General) ; R5-920
    Subject code 360
    Language English
    Publishing date 2020-02-01T00:00:00Z
    Publisher Peytchinski Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: ANTIBIOTIC SUSCEPTIBILITY/RESISTANCE AMONG SALMONELLA SPECIES ISOLATED IN NON-HOSPITALISED PATIENTS IN THE CANTON OF SARAJEVO

    Mufida Aljicevic / Armin Cikotic / Sabaheta Bektas / Sabina Mahmutovic Vranic / Velma Rebic / Amila Abduzaimovic / Adem Cemerlic

    Journal of IMAB, Vol 25, Iss 2, Pp 2532-

    2019  Volume 2536

    Abstract: Background: Salmonellosis, a disease which occurs following the consumption of food contaminated with salmonella, is most frequently present in young children and older immunocompromised individuals. This condition must be treated with antibiotics. The ... ...

    Abstract Background: Salmonellosis, a disease which occurs following the consumption of food contaminated with salmonella, is most frequently present in young children and older immunocompromised individuals. This condition must be treated with antibiotics. The increased degree of morbidity comes in relation to the increased resistance of Sallmonellae species to antibiotics. Resistance has considerably been increased in approximately the last twenty years, thanks mostly to the establishment of diagnoses ex juvantibus, the prescription of therapies without antimicrobial susceptibility/resistance testing, as well as the massive, unjustified usage of antibiotics. Purpose: The goal of this study was to examine the representation of antibiotic susceptibility/resistance of Salmonella species isolated in non-hospitalised patients. Materials and methods: In a microbiological laboratory in the Institute for Public Health Canton of Sarajevo (Bosnia and Herzegovina), analysed were samples of stool and urine of non-hospitalised patients with our without developed symptoms of salmonellosis in the period from one year. Results: Of the total 69 patients infected with salmonella, in 65 (94.2%) S. enteritidis group D was isolated, in 3 (4.3%) S. species group B, and in 1 (1.4%) patient there was a S. enteritidis group D and a S. species group C. Isolated strains were resistant to Ampicillin in 63 (91.3%) patients, while to Ciprofloxacin and Bactrim there was no established resistance. Conclusions: The most commonly isolated bacterial strain was S. enteritidis group D. Isolated strains show different susceptibility/resistance to tested antibiotics, and thus the completion of an antimicrobial susceptibility/resistance test is necessary before adding an antibiotic to the patient’s treatment.
    Keywords Salmonella species ; salmonellosis ; antimicrobial susceptibility test ; Dentistry ; RK1-715 ; Medicine (General) ; R5-920
    Subject code 616
    Language English
    Publishing date 2019-05-01T00:00:00Z
    Publisher Peytchinski Publishing
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Detection of Mycoplasma genitalium in female cervical samples by Multitarget Real-Time PCR

    Sabina Mahmutović-Vranić / Edina Bešlagić / Justin Hardick / Maida Šlaković / Charlotte A. Gaydos

    Bosnian Journal of Basic Medical Sciences, Vol 7, Iss

    2007  Volume 2

    Abstract: Mycoplasma genitalum (MG) is associated with variety of urogenital infections such as non-gonococcal urethritis (NGU), endometritis and cervicitis. The objective of this study was to demonstrate and evaluate a research polymerase chain reaction (PCR) ... ...

    Abstract Mycoplasma genitalum (MG) is associated with variety of urogenital infections such as non-gonococcal urethritis (NGU), endometritis and cervicitis. The objective of this study was to demonstrate and evaluate a research polymerase chain reaction (PCR) assay, for the detection of MG in cervical samples of a tested population of women attending gynecology clinics in Bosnia and Herzegovina. The Multitarget Real-Time (MTRT) PCR, utilizing the ABI 7900HT, the sequence detection system, was performed for the detection of MG. Cervical samples (N=97) from females were divided into three types of patient groups: Group 1: patients who had known abnormal clinical cytology reports (N=34); Group 2: patients who reported a history of genitourinary infections (N=22); and Group 3: patients not in either groups 1 or 2 (N=41). Overall, 14,43% (14/97) of those tested were positive for MG. A positive sample was defined as having a cycle threshold cross point (Ct) < 40,0 with a fluorescent detection comparable to the low positive control utilized during the run. This study validated the use of MTRT PCR as a reliable method for the detection of MG in clinical specimens and should facilitate large-scale screening for this organism.
    Keywords Mycoplasmagenitalium ; Multitarget real-time PCR ; Medicine (General) ; R5-920
    Language English
    Publishing date 2007-05-01T00:00:00Z
    Publisher Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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