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  1. Article ; Online: Anomalous behavior in entanglement speed profile through spin chains.

    Sadeghi, Fatemeh / Motamedifar, Mostafa / Golshani, Mojtaba

    Physical review. E

    2024  Volume 109, Issue 4-1, Page(s) 44107

    Abstract: The origin of the uniform Dzyaloshinskii-Moriya interaction (DMI), which is responsible for the creation of chiral magnetism, has been the subject of extensive research. Recently, modern technology has allowed for its production and utilization in a ... ...

    Abstract The origin of the uniform Dzyaloshinskii-Moriya interaction (DMI), which is responsible for the creation of chiral magnetism, has been the subject of extensive research. Recently, modern technology has allowed for its production and utilization in a modulated form. Not only can magnetic phases of spin chains be enriched by the presence of such a potential as detailed in Japaridze et al. [Phys. Rev. E 104, 014134 (2021)10.1103/PhysRevE.104.014134], but the capacity of such systems for information transmission is also greatly enhanced. The current paper examines the impact of a staggered pattern of DMI (STDMI) on a chain with a substrate XX Heisenberg interaction. It is demonstrated how enhancing the intensity of this coupling improves the propagation of an entangled quantum state. Additionally, as our analysis has shown, the initial condition over the system's state has a profound effect on the speed at which entanglement spreads. The aberrant behavior of the entanglement's speed profile in response to fine-tuning of the phase factor which adjusts the initial state is the focus of this paper. This anomalous behavior is characterized by dramatic drops in speed for certain phase factor values. We have also shown that, using wave interference principles, we can predict exactly why these phenomena occur. This research will pave the way for additional studies on STDMI and its potential applications in the field of quantum information.
    Language English
    Publishing date 2024-05-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2844562-4
    ISSN 2470-0053 ; 2470-0045
    ISSN (online) 2470-0053
    ISSN 2470-0045
    DOI 10.1103/PhysRevE.109.044107
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  2. Article ; Online: Entanglement transmission due to the Dzyaloshinskii-Moriya interaction.

    Motamedifar, Mostafa / Sadeghi, Fatemeh / Golshani, Mojtaba

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 2932

    Abstract: We revisited the effectiveness of state and entanglement transmission through a spin-chain-based quantum channel while altering the system parameters and the channel's initial state. Our research is focused on the spin-1/2 XX chain with Dzyaloshinskii- ... ...

    Abstract We revisited the effectiveness of state and entanglement transmission through a spin-chain-based quantum channel while altering the system parameters and the channel's initial state. Our research is focused on the spin-1/2 XX chain with Dzyaloshinskii-Moriya (DM) interaction and the aim is to measure entanglement dynamics between different part of the chain. The speed of entanglement propagation is utilized to probe the evolution of the system via three scenarios: (i) pure Heisenberg interaction, (ii) pure DM interaction, and (iii) collaboration of both types of couplings. To accomplish this, we employ the fermionization approach to obtain an exact solution to the problem. Aside from investigating the influence of magnetic interaction type on entanglement transfer, the effect of selecting the initial state has also been studied. As a result, we discovered that the phase factor regulating the system's initial state induces sharp drops in the propagation speed of entanglement. We also showed how to predict the location of these dramatic drops using the language of wave interference. In addition, the fastest transmission occurs at a special value of the phase factor in which the highest amount of entanglement reaches the system's different pairs. On the other hand, we observe a continuous and flat range of this factor in which the least amount of entanglement is transmitted and for them we have a sharp drop in the speed profile.
    Language English
    Publishing date 2023-02-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-29995-x
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  3. Article ; Online: Formulation and optimization of a single-layer coat for targeting budesonide pellets to the descending Colon.

    Soltani, Fatemeh / Kamali, Hossein / Akhgari, Abbas / Afrasiabi Garekani, Hadi / Nokhodchi, Ali / Sadeghi, Fatemeh

    Pharmaceutical development and technology

    2024  Volume 29, Issue 3, Page(s) 212–220

    Abstract: The current budesonide formulations are inadequate for addressing left-sided colitis, and patients might hesitate to use an enema for a prolonged time. This study focuses on developing a single-layer coating for budesonide pellets targeting the ... ...

    Abstract The current budesonide formulations are inadequate for addressing left-sided colitis, and patients might hesitate to use an enema for a prolonged time. This study focuses on developing a single-layer coating for budesonide pellets targeting the descending colon. Pellets containing budesonide (1.5%w/w), PVP K30 (5%w/w), lactose monohydrate (25%w/w) and Avicel pH 102 (68.5%w/w) were prepared using extrusion spheronization technique. Coating formulations were designed using response surface methodology with pH and time-dependent Eudragits. Dissolution tests were conducted at different pH levels (1.2, 6.5, 6.8, and 7.2). Optimal coating formulation, considering coating level and the Eudragit (S + L) ratio to the total coating weight, was determined. Budesonide pellets were coated with the optimized composition and subjected to continuous dissolution testing simulating the gastrointestinal tract. The coating, with 48% S, 12% L, and 40% RS at a 10% coating level, demonstrated superior budesonide delivery to the descending colon. Coated pellets had a spherical shape with a uniform 30 µm thickness coating, exhibiting pH and time-dependent release. Notably, zero-order release kinetics was observed for the last 9 h in colonic conditions. The study suggests that an optimized single-layer coating, incorporating pH and time-dependent polymers, holds promise for consistently delivering budesonide to the descending colon.
    MeSH term(s) Humans ; Budesonide ; Drug Delivery Systems ; Colon ; Colon, Descending ; Solubility ; Drug Implants ; Polymethacrylic Acids
    Chemical Substances Budesonide (51333-22-3) ; methylmethacrylate-methacrylic acid copolymer (25086-15-1) ; Drug Implants ; Polymethacrylic Acids
    Language English
    Publishing date 2024-03-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 1331774-x
    ISSN 1097-9867 ; 1083-7450
    ISSN (online) 1097-9867
    ISSN 1083-7450
    DOI 10.1080/10837450.2024.2321250
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5043: Show issues Location:
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  4. Article ; Online: Optimizing scan time and bayesian penalized likelihood reconstruction algorithm in copper-64 PET/CT imaging: a phantom study.

    Monsef, Abbas / Sheikhzadeh, Peyman / Steiner, Joseph R / Sadeghi, Fatemeh / Yazdani, Mohammadreza / Ghafarian, Pardis

    Biomedical physics & engineering express

    2024  Volume 10, Issue 4

    Abstract: ... ...

    Abstract Objectives
    MeSH term(s) Phantoms, Imaging ; Bayes Theorem ; Algorithms ; Positron Emission Tomography Computed Tomography/methods ; Signal-To-Noise Ratio ; Copper Radioisotopes ; Image Processing, Computer-Assisted/methods ; Likelihood Functions ; Humans
    Language English
    Publishing date 2024-05-14
    Publishing country England
    Document type Journal Article
    ISSN 2057-1976
    ISSN (online) 2057-1976
    DOI 10.1088/2057-1976/ad3e00
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  5. Article ; Online: A Novel Multi-Objective Binary Chimp Optimization Algorithm for Optimal Feature Selection: Application of Deep-Learning-Based Approaches for SAR Image Classification.

    Sadeghi, Fatemeh / Larijani, Ata / Rostami, Omid / Martín, Diego / Hajirahimi, Parisa

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 3

    Abstract: Removing redundant features and improving classifier performance necessitates the use of meta-heuristic and deep learning (DL) algorithms in feature selection and classification problems. With the maturity of DL tools, many data-driven polarimetric ... ...

    Abstract Removing redundant features and improving classifier performance necessitates the use of meta-heuristic and deep learning (DL) algorithms in feature selection and classification problems. With the maturity of DL tools, many data-driven polarimetric synthetic aperture radar (POLSAR) representation models have been suggested, most of which are based on deep convolutional neural networks (DCNNs). In this paper, we propose a hybrid approach of a new multi-objective binary chimp optimization algorithm (MOBChOA) and DCNN for optimal feature selection. We implemented the proposed method to classify POLSAR images from San Francisco, USA. To do so, we first performed the necessary preprocessing, including speckle reduction, radiometric calibration, and feature extraction. After that, we implemented the proposed MOBChOA for optimal feature selection. Finally, we trained the fully connected DCNN to classify the pixels into specific land-cover labels. We evaluated the performance of the proposed MOBChOA-DCNN in comparison with nine competitive methods. Our experimental results with the POLSAR image datasets show that the proposed architecture had a great performance for different important optimization parameters. The proposed MOBChOA-DCNN provided fewer features (27) and the highest overall accuracy. The overall accuracy values of MOBChOA-DCNN on the training and validation datasets were 96.89% and 96.13%, respectively, which were the best results. The overall accuracy of SVM was 89.30%, which was the worst result. The results of the proposed MOBChOA on two real-world benchmark problems were also better than the results with the other methods. Furthermore, it was shown that the MOBChOA-DCNN performed better than methods from previous studies.
    Language English
    Publishing date 2023-01-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23031180
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  6. Article ; Online: Effects of active coatings based on soluble portion of zedo gum on physicochemical, microbial, and antioxidant enzymes characteristics of white shrimp

    Joukar, Fatemeh / Sadeghi, Fatemeh / Naseri, Mahmood / Valizadeh, Shahriyar / Esteghlal, Sara / Hosseini, Seyed Mohammad Hashem

    Food Measure. 2023 Apr., v. 17, no. 2 p.1535-1547

    2023  

    Abstract: The focus of current study was on the effectiveness of active coatings based on water-soluble portion of zedo gum (WZG) enriched with different concentrations of essential oils, obtained from Shirazi thyme and cinnamon (SEO and CEO, respectively) and ... ...

    Abstract The focus of current study was on the effectiveness of active coatings based on water-soluble portion of zedo gum (WZG) enriched with different concentrations of essential oils, obtained from Shirazi thyme and cinnamon (SEO and CEO, respectively) and their mixture, on the shelf-life of trimmed white shrimp. The coated shrimps were compared with two sets of controls in terms of antioxidant enzymes activities, bacteriological quality, physicochemical characteristics, and sensory evaluation during cold storage (4 ± 1 °C) for 10 days. The decreasing trend in the antioxidant enzymes activities was significantly retarded in the presence of active coatings. After 10 days, the maximum enzymes activity was measured in the coated shrimps containing EOs in the following order: 1% CEO > 1% CEO/SEO > 1% SEO. WZG active solutions revealed positive influence on decreasing the bacterial count to around 2 log CFU/g. Adhesive coatings also reduced the chemical deterioration indices significantly (P < 0.05). The sensory parameters and acceptability of shrimps were increased in the presence of EOs.
    Keywords antioxidants ; cinnamon ; cold storage ; microbiological quality ; plate count ; sensory evaluation ; shelf life ; shrimp ; thyme ; water solubility
    Language English
    Dates of publication 2023-04
    Size p. 1535-1547.
    Publishing place Springer US
    Document type Article ; Online
    ZDB-ID 2754612-3
    ISSN 2193-4134 ; 2193-4126
    ISSN (online) 2193-4134
    ISSN 2193-4126
    DOI 10.1007/s11694-022-01720-8
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  7. Article: Physical modification of Lepidium perfoliatum seed gum using cold atmospheric-pressure plasma treatment

    Sadeghi, Fatemeh / Koocheki, Arash / Shahidi, Fakhri

    Food hydrocolloids. 2021 Nov., v. 120

    2021  

    Abstract: In the present study, cold atmospheric-pressure plasma treatments (5 and 10 kV for 4–20 min) were used for the modification of Lepidium perfoliatum seed gum (LPSG). The content of carbonyl and carboxyl groups, as well as the water-solubility of LPSG ... ...

    Abstract In the present study, cold atmospheric-pressure plasma treatments (5 and 10 kV for 4–20 min) were used for the modification of Lepidium perfoliatum seed gum (LPSG). The content of carbonyl and carboxyl groups, as well as the water-solubility of LPSG increased after the plasma treatments; however, the numbers of surface hydroxyl groups decreased when 5kVplasma was used. Molecular weight and polydispersity index of LPSG significantly increased after exposure to the air plasma at 5 kV, whereas a significant decrease in molecular weight and a significant increase in polydispersity was observed with increase in the plasma voltage and treatment time. The molecular conformation of LPSG changed to a more disordered or less ordered form when higher plasma voltage was used. Results demonstrated that cleavage of C–O–C as well as formation of C–O–C bonds occurred during plasma treatments. The elastic components were always higher than the viscous one meaning that all native LPSG and modified gums dispersions had weak gel characteristics. However, plasma treated gums at 5 kV had stronger intertwined network than the native gum. Meanwhile, the viscoelasticity of treated LPSG at 10 kV was weaker than the native one. All modified and unmodified LPSGs dispersions revealed pseudoplastic flow behavior. 5 kV treated samples displayed higher apparent viscosity, while lower values of apparent viscosity was achieved after plasma treatments at 10 kV. Therefore, this study confirms the eminent ability of cold plasma as a means to modify or modulate food polysaccharides properties.
    Keywords Lepidium perfoliatum ; air ; atmospheric pressure ; cold ; electric potential difference ; gels ; hydrocolloids ; molecular conformation ; molecular weight ; plant gums ; viscoelasticity ; viscosity ; water solubility
    Language English
    Dates of publication 2021-11
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 742742-6
    ISSN 1873-7137 ; 0268-005X
    ISSN (online) 1873-7137
    ISSN 0268-005X
    DOI 10.1016/j.foodhyd.2021.106902
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    In stock of ZB MED Bonn / Germany

    Z 4414: Show issues

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  8. Article ; Online: Healing effects of autologous platelet gel and growth factors on cutaneous leishmaniasis wounds in addition to antimony; a self-controlled clinical trial with randomized lesion assignment.

    Shadmand, Enayatollah / Solhjoo, Kavous / Taghipour, Ali / Tayer, Akbar Hashemi / Sadeghi, Fatemeh / Meshkin, Ahmad

    BMC research notes

    2023  Volume 16, Issue 1, Page(s) 200

    Abstract: Objective: Autologous platelet gel (APG) is used in most surgeries to treat a variety of tissue defects because of its healing factors composition. This randomized parallel clinical trial was conducted to investigate the healing effects of APG on ... ...

    Abstract Objective: Autologous platelet gel (APG) is used in most surgeries to treat a variety of tissue defects because of its healing factors composition. This randomized parallel clinical trial was conducted to investigate the healing effects of APG on cutaneous leishmaniasis (CL) wounds. Eighteen male patients with CL wounds were recruited and followed for two months. The patients had more than one cutaneous wound, one of which was examined as the control and the other one as the intervention wound. APG was applied to the intervention wounds once a week, up to eight times. The primary endpoint was wound healing which defined as complete epithelialization and tissue granulation. Other clinical evaluation criteria were assessment of the wound size, and histopathology analyses.
    Results: Of 18 patients, 15 patients completed the trial (83.3%, mean age 28 years). The use of APG on the wounds was associated with complete and faster healing in 66% of the wounds and partial healing in 34% of the wounds. During the study, none of the control wounds were completely healed. The wound area in the intervention cases showed a statistically significant decrease throughout the study (P < 0.01) compared with controls. Following treatment of CL lesions with APG, the inflammatory process in the epidermis and dermis were decreased significantly (P < 0.01) compared with controls.
    Conclusion: Our preliminary results confirm the clinical healing improvement described in the literature for APG-GF treatment of chronic non-leishmania wounds via immunomodulation.
    Trial registration: IRCT, IRCT20190212042694N1. Registered 20 February 2019, https://en.irct.ir/trial/37522.
    MeSH term(s) Humans ; Male ; Adult ; Antimony ; Wound Healing ; Intercellular Signaling Peptides and Proteins ; Blood Platelets ; Leishmaniasis, Cutaneous/drug therapy
    Chemical Substances Antimony (9IT35J3UV3) ; Intercellular Signaling Peptides and Proteins
    Language English
    Publishing date 2023-09-09
    Publishing country England
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2413336-X
    ISSN 1756-0500 ; 1756-0500
    ISSN (online) 1756-0500
    ISSN 1756-0500
    DOI 10.1186/s13104-023-06470-4
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  9. Article: The effects of various penalty parameter values in Q.Clear algorithm for rectal cancer detection on

    Sadeghi, Fatemeh / Sheikhzadeh, Peyman / Farzanehfar, Saeed / Ghafarian, Pardis / Moafpurian, Yalda / Ay, Mohammadreza

    EJNMMI physics

    2023  Volume 10, Issue 1, Page(s) 63

    Abstract: Background: The Q.Clear algorithm is a fully convergent iterative image reconstruction technique. We hypothesize that different PET/CT scanners with distinct crystal properties will require different optimal settings for the Q.Clear algorithm. Many ... ...

    Abstract Background: The Q.Clear algorithm is a fully convergent iterative image reconstruction technique. We hypothesize that different PET/CT scanners with distinct crystal properties will require different optimal settings for the Q.Clear algorithm. Many studies have investigated the improvement of the Q.Clear reconstruction algorithm on PET/CT scanner with LYSO crystals and SiPM detectors. We propose an optimum penalization factor (β) for the detection of rectal cancer and its metastases using a BGO-based detector PET/CT system which obtained via accurate and comprehensive phantom and clinical studies.
    Methods: 18
    Results: OSEM had 11.5-18.6% higher BV than Q.Clear using β value of 500. Conversely, RC from OSEM to Q.Clear using β value of 500 decreased by 3.3-7.7% for a sphere with a diameter of 10 mm and 2.5-5.1% for a sphere with a diameter of 37 mm. Furthermore, the increment of contrast using a β value of 500 was 5.2-8.1% in the smallest spheres compared to OSEM. When the β value was increased from 100 to 500, the SNR increased by 49.1% and 30.8% in the smallest and largest spheres at LBR 2:1, respectively. At LBR of 8:1, the relative difference of SNR between β value of 100 and 500 was 43.7% and 44.0% in the smallest and largest spheres, respectively. In the clinical study, as β increased from 100 to 500, the SUVmax decreased by 47.7% in small and 31.1% in large lesions. OSEM demonstrated the least SUVmax, SBR, and contrast. The decrement of SBR and contrast using OSEM were 13.6% and 12.9% in small and 4.2% and 3.4%, respectively, in large lesions.
    Conclusions: Implementing Q.Clear enhances quantitative accuracies through a fully convergent voxel-based image approach, employing a penalization factor. In the BGO-based scanner, the optimal β value for small lesions ranges from 200 for LBR 2:1 to 300 for LBR 8:1. For large lesions, the optimal β value is between 400 for LBR 2:1 and 500 for LBR 8:1. We recommended β value of 300 for small lesions and β value of 500 for large lesions in clinical study.
    Language English
    Publishing date 2023-10-16
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2768912-8
    ISSN 2197-7364
    ISSN 2197-7364
    DOI 10.1186/s40658-023-00587-y
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  10. Article ; Online: Phantom and clinical evaluation of Block Sequential Regularized Expectation Maximization (BSREM) reconstruction algorithm in 68Ga-PSMA PET-CT studies.

    Sadeghi, Fatemeh / Sheikhzadeh, Peyman / Kasraie, Nima / Farzanehfar, Saeed / Abbasi, Mehrshad / Salehi, Yalda / Ay, Mohammadreza

    Physical and engineering sciences in medicine

    2023  Volume 46, Issue 3, Page(s) 1297–1308

    Abstract: In this study, we aimed to examine the effect of varying β-values in the block sequential regularized expectation maximization (BSREM) algorithm under differing lesion sizes to determine an optimal penalty factor for clinical application. The National ... ...

    Abstract In this study, we aimed to examine the effect of varying β-values in the block sequential regularized expectation maximization (BSREM) algorithm under differing lesion sizes to determine an optimal penalty factor for clinical application. The National Electrical Manufacturers Association phantom and 15 prostate cancer patients were injected with 68Ga-PSMA and scanned using a GE Discovery IQ PET/CT scanner. Images were reconstructed using ordered subset expectation maximization (OSEM) and BSREM with different β-values. Then, the background variability (BV), contrast recovery, signal-to-noise ratio, and lung residual error were measured from the phantom data, and the signal-to-background ratio (SBR) and contrast from the clinical data. The increment of BV using a β-value of 100 was 120.0%, and the decrement of BV using a β-value of 1000 was 40.5% compared to OSEM. As β decreased from 1000 to 100, the [Formula: see text] increased by 59.0% for a sphere with a diameter of 10 mm and 26.4% for a sphere with a diameter of 37 mm. Conversely, [Formula: see text] increased by 140.5% and 29.0% in the smallest and largest spheres, respectively. Furthermore, the Δ[Formula: see text] and Δ[Formula: see text] were - 41.1% and - 36.7%, respectively. In the clinical study, OSEM exhibited the lowest SBR and contrast. When the β-value was reduced from 500 to 100, the SBR and contrast increased by 69.7% and 71.8% in small and 35.6% and 33.0%, respectively, in large lesions. Moreover, the optimal β-value decreased as lesion size decreased. In conclusion, a β-value of 400 is optimal for small lesion reconstruction, while β-values of 600 and 500 are optimal for large lesions in phantom and clinical studies, respectively.
    MeSH term(s) Humans ; Male ; Algorithms ; Image Processing, Computer-Assisted/methods ; Positron Emission Tomography Computed Tomography/methods ; Tomography, X-Ray Computed
    Chemical Substances gallium 68 PSMA-11
    Language English
    Publishing date 2023-07-13
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2662-4737
    ISSN (online) 2662-4737
    DOI 10.1007/s13246-023-01299-4
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