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  1. Article: Complete Heart Block Induced Torsades de Pointes.

    Szumowski, Benjamin A / Beshay-Taylor, Youstina Mary / Sadek, Ramy / Attia, Nader

    Cureus

    2024  Volume 16, Issue 2, Page(s) e55169

    Abstract: High-degree atrioventricular node block is a known cause of bradycardia. Heart rate and QT interval have an inverse relation. Therefore, bradycardia can lead to prolonged QT interval, which can predispose patients to Torsades de Pointes, a life- ... ...

    Abstract High-degree atrioventricular node block is a known cause of bradycardia. Heart rate and QT interval have an inverse relation. Therefore, bradycardia can lead to prolonged QT interval, which can predispose patients to Torsades de Pointes, a life-threatening arrhythmia. Correcting the underlying etiology can often reverse the arrhythmia and prevent recurrence. For this reason, recognizing the etiology of this arrhythmia plays an essential role in management.
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.55169
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Deep learning Binary/Multi classification for music's brainwave entrainment beats.

    A Sadek, Rowayda / Khalifa, Alaa A / Elfattah, Marwa M A

    PeerJ. Computer science

    2023  Volume 9, Page(s) e1642

    Abstract: The last two decades have seen the emergence of a brand-new kind of music known as digital brain stimulant, also known as instrumental music or music without lyrics, which mostly comprises entrainment beats. While listening to it has the same ability to ... ...

    Abstract The last two decades have seen the emergence of a brand-new kind of music known as digital brain stimulant, also known as instrumental music or music without lyrics, which mostly comprises entrainment beats. While listening to it has the same ability to affect the brain as taking medication, it also has the risk of having a negative impact or encouraging unwanted behavior. This sparked the interest of a large number of studies in the psychological and physiological effects of music's brainwave entrainment beats on listeners. These studies started to categorize and examine how musical beats affected brainwave entrainment by looking at electroencephalogram (EEG) signals. Although this categorization represents a step forward for the early research efforts, it is constrained by the difficulty of having each musical track and conducting EEG tests on humans exposed to distortion due to noise in order to determine its influence. The work proposed in this article continues to explore this topic but in a novel, simple, accurate, and reliable categorization procedure based on the music signal elements themselves rather than dependent on EEG. VGGish and YAMNET based transfer deep learning models, are tuned to handle a straightforward, accurate real-time detector for the existence of the music beats inside music files with accuracy of 98.5 and 98.4, respectively. Despite the fact that they yield results that are equivalent, the YAMNET model is more suited for use with mobile devices due to its low power consumption and low latency. The article also proposes modified version of VGGish and YAMNET binary classifying models called BW-VGGish and BW-YAMNET respectively. The modification was to turn the binary classification into multi-classification. These multi-classifiers handle the classification of the influence of music beats (five different brain waves) on human brainwave entrainment with average accuracy of 94.5% and 94.5%, respectively. Since there was a lack of datasets addressing this kind of music, two datasets, the Brainwave Entrainment Beats (BWEB) dataset and the Brainwave Music Manipulation (BWMM) dataset, were generated for classification training and testing. The re-testing on a sample of music files that have their impact on brain waves (with their EEG) in an earlier study is done to strengthen the validity of the proposed work and to overcome the potential limitation of utilizing a music dataset that is not proved with its EEG. The success of the suggested models was demonstrated.
    Language English
    Publishing date 2023-11-03
    Publishing country United States
    Document type Journal Article
    ISSN 2376-5992
    ISSN (online) 2376-5992
    DOI 10.7717/peerj-cs.1642
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Reduced Graphene Oxide/Barium Ferrite Ceramic Nanocomposite Synergism for High EMI Wave Absorption.

    Sadek, Ramy / Sharawi, Mohammad S / Dubois, Charles / Tantawy, Hesham / Chaouki, Jamal

    ACS omega

    2023  Volume 8, Issue 17, Page(s) 15099–15113

    Abstract: The developed nanocomposite exhibits significantly enhanced shielding performance due to the synergistic effect of high dielectric and magnetic loss materials, which modifies the material's impedance and improves its absorption ability. Different weight ... ...

    Abstract The developed nanocomposite exhibits significantly enhanced shielding performance due to the synergistic effect of high dielectric and magnetic loss materials, which modifies the material's impedance and improves its absorption ability. Different weight percentages (0, 1, 5, 10, 15, 20, and 25 wt %) of thermally treated chemically reduced graphene oxide (TCRGO) were combined with two types of magnets, barium hexaferrite (BF) and magnetite (MAG), using a dry powder compaction technique to produce binary ceramic nanocomposite sheets. The shielding performance of a 1 mm thick compressed nanoceramic sheet over the X-band was evaluated using a vector network analyzer. The 25% TCRGO showed high shielding performance for both BF and MAG, while BF had a total shielding efficiency (SET) that exceeded MAG by 130%. The SET of 25 wt % TCRGO/BF was 52 dB, with a 41 dB absorption shielding efficiency (SEA). Additionally, the effect of different levels of incident electromagnetic wave power (0.001-1000 mW) at various thicknesses (1, 2, and 5 mm) was explored. At 1000 mW, the 5 mm TCRGO/BF had an SET of 99 dB, an SEA of 91 dB, and a reflection shielding efficiency (SER) of 8 dB. The use of BF as a hard magnet paired with TCRGO exhibited excellent and stable electromagnetic shielding performance.
    Language English
    Publishing date 2023-04-20
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.2c08168
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The Oil Drop Sign.

    Sadek, Ramy / Mansoor, André M

    Journal of general internal medicine

    2019  Volume 34, Issue 9, Page(s) 1946

    MeSH term(s) Adult ; Female ; Humans ; Nail Diseases/complications ; Nail Diseases/diagnosis ; Psoriasis/complications ; Psoriasis/diagnosis ; Psoriasis/drug therapy
    Language English
    Publishing date 2019-07-16
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 639008-0
    ISSN 1525-1497 ; 0884-8734
    ISSN (online) 1525-1497
    ISSN 0884-8734
    DOI 10.1007/s11606-019-05159-4
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2205: Show issues Location:
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  5. Article: Leukemia Cutis in Skin of Color.

    Adjei, Susuana / Temiz, Laurie A / Miller, Austinn C / Sadek, Rashid / Grush, Andrew E / Tyring, Stephen K

    Journal of drugs in dermatology : JDD

    2023  Volume 22, Issue 7, Page(s) 687–689

    Abstract: The various presentations of many dermatologic conditions among various skin types are slowly being elucidated throughout the recent years. These differences present as an issue as it leads to delayed diagnosis, treatment, and poorer quality of life. ... ...

    Abstract The various presentations of many dermatologic conditions among various skin types are slowly being elucidated throughout the recent years. These differences present as an issue as it leads to delayed diagnosis, treatment, and poorer quality of life. Herein, we present the characteristics of leukemia cutis in a skin of color patient with diagnosed chronic myelomonocytic leukemia. Adjei S, Temiz LA, Miller AC, et al. Leukemia cutis in skin of color. J Drugs Dermatol. 2023;22(7):687-689. doi:10.36849/JDD.7020.
    MeSH term(s) Humans ; Leukemia/diagnosis ; Quality of Life ; Skin ; Skin Neoplasms/diagnosis ; Skin Neoplasms/ethnology ; Skin Neoplasms/therapy ; Skin Pigmentation
    Language English
    Publishing date 2023-06-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2145090-0
    ISSN 1545-9616
    ISSN 1545-9616
    DOI 10.36849/JDD.7020
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    Zs.A 5931: Show issues Location:
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  6. Article ; Online: Identification and Functional Characterization of Alternative Transcripts of LncRNA HNF1A-AS1 and Their Impacts on Cell Growth, Differentiation, Liver Diseases, and in Response to Drug Induction.

    Jin, Jing / Nguyen, Le Tra Giang / Wassef, Andrew / Sadek, Ragui / Schmitt, Timothy M / Guo, Grace L / Rasmussen, Theodore P / Zhong, Xiao-Bo

    Non-coding RNA

    2024  Volume 10, Issue 2

    Abstract: The long non-coding RNA (lncRNA) hepatocyte nuclear factor-1 alpha (HNF1A) antisense RNA 1 (HNF1A-AS1) is an important lncRNA for liver growth, development, cell differentiation, and drug metabolism. Like many lncRNAs, HNF1A-AS1 has multiple annotated ... ...

    Abstract The long non-coding RNA (lncRNA) hepatocyte nuclear factor-1 alpha (HNF1A) antisense RNA 1 (HNF1A-AS1) is an important lncRNA for liver growth, development, cell differentiation, and drug metabolism. Like many lncRNAs, HNF1A-AS1 has multiple annotated alternative transcripts in the human genome. Several fundamental biological questions are still not solved: (1) How many transcripts really exist in biological samples, such as liver samples and liver cell lines? (2) What are the expression patterns of different alternative HNF1A-AS1 transcripts at different conditions, including during cell growth and development, after exposure to xenobiotics (such as drugs), and in disease conditions, such as metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol-associated liver disease (ALD) cirrhosis, and obesity? (3) Does the siRNA used in previous studies knock down one or multiple transcripts? (4) Do different transcripts have the same or different functions for gene regulation? The presented data confirm the existence of several annotated HNF1A-AS1 transcripts in liver samples and cell lines, but also identify some new transcripts, which are not annotated in the Ensembl genome database. Expression patterns of the identified HNF1A-AS1 transcripts are highly correlated with the cell differentiation of matured hepatocyte-like cells from human embryonic stem cells (hESC), growth and differentiation of HepaRG cells, in response to rifampicin induction, and in various liver disease conditions. The expression levels of the HNF1A-AS1 transcripts are also highly correlated to the expression of cytochrome P450 enzymes, such as CYP3A4, during HepaRG growth, differentiation, and in response to rifampicin induction.
    Language English
    Publishing date 2024-04-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2813993-8
    ISSN 2311-553X ; 2311-553X
    ISSN (online) 2311-553X
    ISSN 2311-553X
    DOI 10.3390/ncrna10020028
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  7. Article: Superior quality chemically reduced graphene oxide for high performance EMI shielding materials

    Sadek, Ramy / Sharawi, Mohammad S. / Dubois, Charles / Tantawy, Hesham / Chaouki, Jamal

    RSC advances. 2022 Aug. 12, v. 12, no. 35

    2022  

    Abstract: The chemical reduction process of graphene oxide combined with a mild and controllable thermal treatment under vacuum at 200 °C for 4 hours provided a cost-effective, scalable, and high-yield route for Reduced Graphene Oxide (RGO) industrial production ... ...

    Abstract The chemical reduction process of graphene oxide combined with a mild and controllable thermal treatment under vacuum at 200 °C for 4 hours provided a cost-effective, scalable, and high-yield route for Reduced Graphene Oxide (RGO) industrial production and became a potential candidate for producing electromagnetic interference (EMI) shielding. We investigated graphite, and RGO using l-ascorbic acid and Sodium borohydride before and after thermal treatment by carefully evaluating the chemical and morphological structures. The thermally treated l-ascorbic Acid reduction route (TCRGOL) conductivity was 2.14 × 10³ S m⁻¹ and total shielding efficiency (SET) based on mass loadings per area of shielding was 94 dB with about one-tenth less graphite weight and surpassing other graphene reduction mechanisms in the frequency range of 8.2–12.4 GHz, i.e., X-band, at room temperature while being tested using the waveguide line technique. The developed treatment represents valuable progress in the path to chemical reduction using a safe reducing agent and offering superior quality RGO rarely achieved with the top-down technique, providing a high EMI shielding performance.
    Keywords ambient temperature ; ascorbic acid ; chemical reduction ; cost effectiveness ; electromagnetic interference ; graphene ; graphene oxide ; heat treatment ; sodium borohydride
    Language English
    Dates of publication 2022-0812
    Size p. 22608-22622.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ISSN 2046-2069
    DOI 10.1039/d2ra02678c
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Superior quality chemically reduced graphene oxide for high performance EMI shielding materials.

    Sadek, Ramy / Sharawi, Mohammad S / Dubois, Charles / Tantawy, Hesham / Chaouki, Jamal

    RSC advances

    2022  Volume 12, Issue 35, Page(s) 22608–22622

    Abstract: The chemical reduction process of graphene oxide combined with a mild and controllable thermal treatment under vacuum at 200 °C for 4 hours provided a cost-effective, scalable, and high-yield route for Reduced Graphene Oxide (RGO) industrial production ... ...

    Abstract The chemical reduction process of graphene oxide combined with a mild and controllable thermal treatment under vacuum at 200 °C for 4 hours provided a cost-effective, scalable, and high-yield route for Reduced Graphene Oxide (RGO) industrial production and became a potential candidate for producing electromagnetic interference (EMI) shielding. We investigated graphite, and RGO using l-ascorbic acid and Sodium borohydride before and after thermal treatment by carefully evaluating the chemical and morphological structures. The thermally treated l-ascorbic Acid reduction route (TCRGOL) conductivity was 2.14 × 10
    Language English
    Publishing date 2022-08-12
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d2ra02678c
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  9. Article ; Online: A Case Report of a Lebanon Viper (Montivipera bornmuelleri) Envenomation in a Child.

    Tabbara, Faysal / Abdul Nabi, Sarah S / Sadek, Riad / Kazzi, Ziad / El Zahran, Tharwat

    Clinical practice and cases in emergency medicine

    2022  Volume 6, Issue 4, Page(s) 318–322

    Abstract: Introduction: Snake envenomation is a serious public health concern. In the Middle East little is known about snakebite envenomation, which raises several challenges for emergency physicians caring for these patients.: Case report: We report the case ...

    Abstract Introduction: Snake envenomation is a serious public health concern. In the Middle East little is known about snakebite envenomation, which raises several challenges for emergency physicians caring for these patients.
    Case report: We report the case of a five-year-old boy bitten by a rare snake, Montivipera bornmuelleri, who presented to an emergency department in Lebanon. We also discuss the proper management of snake envenomation.
    Conclusion: This case is unique as snakebites in Lebanon are poorly studied, and little is known about the epidemiology and clinical manifestations of local snakebites.
    Language English
    Publishing date 2022-11-25
    Publishing country United States
    Document type Journal Article
    ISSN 2474-252X
    ISSN (online) 2474-252X
    DOI 10.5811/cpcem.2022.2.56176
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A validated LC-MS/MS method for the quantitation of cefazolin in human adipose tissue: Application of EMR-Lipid sorbent as an efficient sample clean-up before mass spectrometric analyses.

    Siemiątkowska, Anna / Wassef, Andrew / Sadek, Ragui / Park, Celine / Yohn, Christine / Brunetti, Luigi / Kagan, Leonid

    Journal of pharmaceutical and biomedical analysis

    2022  Volume 213, Page(s) 114696

    Abstract: A novel, simple, rapid, and sensitive high-performance liquid chromatography-tandem mass spectrometry method was developed to determine cefazolin concentrations in human adipose tissue. Sample preparation was performed by protein precipitation followed ... ...

    Abstract A novel, simple, rapid, and sensitive high-performance liquid chromatography-tandem mass spectrometry method was developed to determine cefazolin concentrations in human adipose tissue. Sample preparation was performed by protein precipitation followed by using Captiva EMR-Lipid plates. The mobile phase consisted of 5 mM ammonium formate and 0.1% formic acid in water and 0.1% formic acid in ACN, and was pumped through a Synergi Fusion-RP column with a gradient elution program at a flow rate of 0.3 mL/min. The mass spectrometer was operated in a positive ion mode. Cloxacillin was used as an internal standard due to the observed cross-signal contribution between cefazolin and
    MeSH term(s) Adipose Tissue ; Animals ; Cefazolin ; Chromatography, Liquid/methods ; Humans ; Lipids ; Rats ; Reproducibility of Results ; Tandem Mass Spectrometry/methods
    Chemical Substances Lipids ; Cefazolin (IHS69L0Y4T)
    Language English
    Publishing date 2022-02-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 604917-5
    ISSN 1873-264X ; 0731-7085
    ISSN (online) 1873-264X
    ISSN 0731-7085
    DOI 10.1016/j.jpba.2022.114696
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