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  1. Article: Complete Heart Block Induced Torsades de Pointes.

    Szumowski, Benjamin A / Beshay-Taylor, Youstina Mary / Sadek, Ramy / Attia, Nader

    Cureus

    2024  Volume 16, Issue 2, Page(s) e55169

    Abstract: High-degree atrioventricular node block is a known cause of bradycardia. Heart rate and QT interval have an inverse relation. Therefore, bradycardia can lead to prolonged QT interval, which can predispose patients to Torsades de Pointes, a life- ... ...

    Abstract High-degree atrioventricular node block is a known cause of bradycardia. Heart rate and QT interval have an inverse relation. Therefore, bradycardia can lead to prolonged QT interval, which can predispose patients to Torsades de Pointes, a life-threatening arrhythmia. Correcting the underlying etiology can often reverse the arrhythmia and prevent recurrence. For this reason, recognizing the etiology of this arrhythmia plays an essential role in management.
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.55169
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Oil Drop Sign.

    Sadek, Ramy / Mansoor, André M

    Journal of general internal medicine

    2019  Volume 34, Issue 9, Page(s) 1946

    MeSH term(s) Adult ; Female ; Humans ; Nail Diseases/complications ; Nail Diseases/diagnosis ; Psoriasis/complications ; Psoriasis/diagnosis ; Psoriasis/drug therapy
    Language English
    Publishing date 2019-07-16
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 639008-0
    ISSN 1525-1497 ; 0884-8734
    ISSN (online) 1525-1497
    ISSN 0884-8734
    DOI 10.1007/s11606-019-05159-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Reduced Graphene Oxide/Barium Ferrite Ceramic Nanocomposite Synergism for High EMI Wave Absorption.

    Sadek, Ramy / Sharawi, Mohammad S / Dubois, Charles / Tantawy, Hesham / Chaouki, Jamal

    ACS omega

    2023  Volume 8, Issue 17, Page(s) 15099–15113

    Abstract: The developed nanocomposite exhibits significantly enhanced shielding performance due to the synergistic effect of high dielectric and magnetic loss materials, which modifies the material's impedance and improves its absorption ability. Different weight ... ...

    Abstract The developed nanocomposite exhibits significantly enhanced shielding performance due to the synergistic effect of high dielectric and magnetic loss materials, which modifies the material's impedance and improves its absorption ability. Different weight percentages (0, 1, 5, 10, 15, 20, and 25 wt %) of thermally treated chemically reduced graphene oxide (TCRGO) were combined with two types of magnets, barium hexaferrite (BF) and magnetite (MAG), using a dry powder compaction technique to produce binary ceramic nanocomposite sheets. The shielding performance of a 1 mm thick compressed nanoceramic sheet over the X-band was evaluated using a vector network analyzer. The 25% TCRGO showed high shielding performance for both BF and MAG, while BF had a total shielding efficiency (SET) that exceeded MAG by 130%. The SET of 25 wt % TCRGO/BF was 52 dB, with a 41 dB absorption shielding efficiency (SEA). Additionally, the effect of different levels of incident electromagnetic wave power (0.001-1000 mW) at various thicknesses (1, 2, and 5 mm) was explored. At 1000 mW, the 5 mm TCRGO/BF had an SET of 99 dB, an SEA of 91 dB, and a reflection shielding efficiency (SER) of 8 dB. The use of BF as a hard magnet paired with TCRGO exhibited excellent and stable electromagnetic shielding performance.
    Language English
    Publishing date 2023-04-20
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.2c08168
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Superior quality chemically reduced graphene oxide for high performance EMI shielding materials

    Sadek, Ramy / Sharawi, Mohammad S. / Dubois, Charles / Tantawy, Hesham / Chaouki, Jamal

    RSC advances. 2022 Aug. 12, v. 12, no. 35

    2022  

    Abstract: The chemical reduction process of graphene oxide combined with a mild and controllable thermal treatment under vacuum at 200 °C for 4 hours provided a cost-effective, scalable, and high-yield route for Reduced Graphene Oxide (RGO) industrial production ... ...

    Abstract The chemical reduction process of graphene oxide combined with a mild and controllable thermal treatment under vacuum at 200 °C for 4 hours provided a cost-effective, scalable, and high-yield route for Reduced Graphene Oxide (RGO) industrial production and became a potential candidate for producing electromagnetic interference (EMI) shielding. We investigated graphite, and RGO using l-ascorbic acid and Sodium borohydride before and after thermal treatment by carefully evaluating the chemical and morphological structures. The thermally treated l-ascorbic Acid reduction route (TCRGOL) conductivity was 2.14 × 10³ S m⁻¹ and total shielding efficiency (SET) based on mass loadings per area of shielding was 94 dB with about one-tenth less graphite weight and surpassing other graphene reduction mechanisms in the frequency range of 8.2–12.4 GHz, i.e., X-band, at room temperature while being tested using the waveguide line technique. The developed treatment represents valuable progress in the path to chemical reduction using a safe reducing agent and offering superior quality RGO rarely achieved with the top-down technique, providing a high EMI shielding performance.
    Keywords ambient temperature ; ascorbic acid ; chemical reduction ; cost effectiveness ; electromagnetic interference ; graphene ; graphene oxide ; heat treatment ; sodium borohydride
    Language English
    Dates of publication 2022-0812
    Size p. 22608-22622.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ISSN 2046-2069
    DOI 10.1039/d2ra02678c
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Superior quality chemically reduced graphene oxide for high performance EMI shielding materials.

    Sadek, Ramy / Sharawi, Mohammad S / Dubois, Charles / Tantawy, Hesham / Chaouki, Jamal

    RSC advances

    2022  Volume 12, Issue 35, Page(s) 22608–22622

    Abstract: The chemical reduction process of graphene oxide combined with a mild and controllable thermal treatment under vacuum at 200 °C for 4 hours provided a cost-effective, scalable, and high-yield route for Reduced Graphene Oxide (RGO) industrial production ... ...

    Abstract The chemical reduction process of graphene oxide combined with a mild and controllable thermal treatment under vacuum at 200 °C for 4 hours provided a cost-effective, scalable, and high-yield route for Reduced Graphene Oxide (RGO) industrial production and became a potential candidate for producing electromagnetic interference (EMI) shielding. We investigated graphite, and RGO using l-ascorbic acid and Sodium borohydride before and after thermal treatment by carefully evaluating the chemical and morphological structures. The thermally treated l-ascorbic Acid reduction route (TCRGOL) conductivity was 2.14 × 10
    Language English
    Publishing date 2022-08-12
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d2ra02678c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Role of IL-13, IL-15 and Granulysin in the Pathogenesis of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis.

    Sadek, Michael / Iqbal, Omer / Siddiqui, Fakiha / Till, Sean / Mazariegos, Melissa / Campbell, Edward / Mudaliar, Kumaran / Speiser, Jodi / Bontekoe, Emily / Kouta, Ahmed / Farooqui, Ambar / Daravath, Bharathi / Qneibi, Dalia / Sadek, Ramy / Hoppensteadt, Debra / Fareed, Jawed / Bouchard, Charles

    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis

    2021  Volume 27, Page(s) 1076029620950831

    Abstract: Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are Severe Cutaneous Adverse Reactions (SCARS) characterized by fever and mucocutaneous lesions leading to necrosis and sloughing of the epidermis. Conjunctival lesions are reported in ... ...

    Abstract Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are Severe Cutaneous Adverse Reactions (SCARS) characterized by fever and mucocutaneous lesions leading to necrosis and sloughing of the epidermis. Conjunctival lesions are reported in 85% of patients. The pathogenesis of SJS/TEN/SCARS is not completely understood. It is hypothesized that IL-13, IL-15 and Granulysin expressed in plasma and skin may play a role. We measured the circulating levels of these cytokines in the plasma using ELISA and their expression in the skin using immunofluorescence microscopy. A total of 12 SJS/TEN skin biopsy samples (8 SJS, 2 SJS/TEN overlap and 2 TEN) were analyzed. Biopsy samples from patients with Lichen Planus (an inflammatory condition of the skin and mucous membranes) served as controls. Studies were also performed in human corneal epithelial cells where expression of these cytokines were measured following a challenge with TNF-α (0, 1, 10 and 100 ng/ml). The intensity of immunofluorescence was measured Using Imaris® software. The results showed significantly increased expression of these cytokines in the skin biopsy samples as measured by the average intensities of IL-13 (6.1 x 133.0 ± 4.231 x 10^8), and Granulysin (4.2 x 123.0 ± 4.231 x 10^8) compared to Lichen planus control (3.0 x 123.0 ±1.62 x 10^5). Increased expression of IL-13 and IL-15 were noted in cell culture studies and in the plasma samples when compared to Normal Human Plasma as controls. It is concluded that IL-13, IL-15 and Granulysin play a role in the pathogenesis of SJS/TEN.
    MeSH term(s) Antigens, Differentiation, T-Lymphocyte/blood ; Biomarkers/blood ; Biopsy ; Case-Control Studies ; Cells, Cultured ; Enzyme-Linked Immunosorbent Assay ; Epithelium, Corneal/metabolism ; Fluorescent Antibody Technique ; Humans ; Interleukin-13/blood ; Interleukin-15/blood ; Microscopy, Fluorescence ; Skin/metabolism ; Skin/pathology ; Stevens-Johnson Syndrome/blood ; Stevens-Johnson Syndrome/diagnosis ; Up-Regulation
    Chemical Substances Antigens, Differentiation, T-Lymphocyte ; Biomarkers ; GNLY protein, human ; IL13 protein, human ; IL15 protein, human ; Interleukin-13 ; Interleukin-15
    Language English
    Publishing date 2021-02-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1237357-6
    ISSN 1938-2723 ; 1076-0296
    ISSN (online) 1938-2723
    ISSN 1076-0296
    DOI 10.1177/1076029620950831
    Database MEDical Literature Analysis and Retrieval System OnLINE

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