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  1. Article ; Online: Quality of Life in Octogenarians After Lung Resection Compared to Younger Patients.

    Asemota, Nicole / Saftic, Igor / Tsitsias, Thomas / King, Juliet / Pilling, John / Bille, Andrea

    Clinical lung cancer

    2021  Volume 23, Issue 2, Page(s) e118–e130

    Abstract: Introduction: To evaluate postoperative outcome and quality of life (QOL), comparing patients <80 years old to patients ≥ 80.: Patients and methods: EORTC questionnaires, QLQ-C30 and QLQ-LC13 was used to assess QOL, in patients after surgery. Results ...

    Abstract Introduction: To evaluate postoperative outcome and quality of life (QOL), comparing patients <80 years old to patients ≥ 80.
    Patients and methods: EORTC questionnaires, QLQ-C30 and QLQ-LC13 was used to assess QOL, in patients after surgery. Results were evaluated according to 3 age groups: <70, 70 to 79, and ≥80.
    Results: 106 patients were enrolled with 33 (<70), 25 (70-79), and 48 (≥80) patients per group. The median age was 74 years. 79% of patients had minimally invasive procedures, including 91% of those ≥80. Fifteen patients underwent wedge resections. Complication rates (18%, 32%, and 29%, P = .4) and median length of stay (4, 6, and 5 days, P = .2) were similar in all age groups, with no hospital mortality. One hundred one patients completed the questionnaires. Global QOL was highest among octogenarians. Overall functional and role QOL was higher among octogenarians than 70- to 79-year-olds, with emotional QOL higher than those <70 (P < .05). Social QOL in octogenarians was marginally lower than younger patients. Lung-specific symptom scores were at least 1.5 times lower than those <80 (P = .052). Patients aged 70 to 79 had the worst symptomatic and emotional effect on QOL. Surgical access and preoperative performance status did not affect final QOL across all age groups (P = .9 and P = .065). Among anatomical lung resections, QOL was higher in octogenarians than those 70 to 79 in all domains, and similar or higher than those <70 in most domains.
    Conclusion: Quality of life among octogenarians after surgery remains similar to younger patients even after anatomical lung resection. Surgery in octogenarians is safe, with minimal impact on postoperative QOL.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Carcinoma, Non-Small-Cell Lung/psychology ; Carcinoma, Non-Small-Cell Lung/surgery ; Female ; Follow-Up Studies ; Health Behavior ; Humans ; Lung Neoplasms/psychology ; Lung Neoplasms/surgery ; Male ; Middle Aged ; Octogenarians ; Postoperative Period ; Quality of Life/psychology ; Socioeconomic Factors ; Surveys and Questionnaires
    Language English
    Publishing date 2021-06-27
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 2145146-1
    ISSN 1938-0690 ; 1525-7304
    ISSN (online) 1938-0690
    ISSN 1525-7304
    DOI 10.1016/j.cllc.2021.05.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Posterior mediastinal Müllerian cyst: a rare cause of pain in a young woman.

    Weedle, Rebecca / Conway, Keith / Saftic, Igor / Soo, Alan

    Asian cardiovascular & thoracic annals

    2017  Volume 25, Issue 6, Page(s) 466–468

    Abstract: Thoracic pain in a young woman carries a wide differential diagnosis. We present the case of a 37-year-old woman who presented with thoracic pain due to a posterior mediastinal Müllerian cyst. Excision was performed by left uniportal video-assisted ... ...

    Abstract Thoracic pain in a young woman carries a wide differential diagnosis. We present the case of a 37-year-old woman who presented with thoracic pain due to a posterior mediastinal Müllerian cyst. Excision was performed by left uniportal video-assisted thoracoscopic surgery. This is the first report to describe thoracic pain that resolved with excision of the cyst.
    Language English
    Publishing date 2017-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 1400468-9
    ISSN 1816-5370 ; 0218-4923
    ISSN (online) 1816-5370
    ISSN 0218-4923
    DOI 10.1177/0218492317716588
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  3. Article ; Online: Risks and rewards of the surgical treatment of lung cancer in octogenarians.

    Saftic, Igor / Bille, Andrea / Asemota, Nicole / Berjon de la Vega, Loreto / Routledge, Tom / King, Juliet / Phipps, Karen Harrison / Pilling, John

    Interactive cardiovascular and thoracic surgery

    2021  Volume 33, Issue 6, Page(s) 905–912

    Abstract: Objectives: Surgeons will face an increasing number of octogenarians with lung cancer potentially curable by surgery. The goal of this study was to evaluate short- and long-term outcomes after lung resection.: Methods: We performed a single-centre ... ...

    Abstract Objectives: Surgeons will face an increasing number of octogenarians with lung cancer potentially curable by surgery. The goal of this study was to evaluate short- and long-term outcomes after lung resection.
    Methods: We performed a single-centre study of consecutive patients ≥80 years old, surgically treated for suspected lung cancer between 2009 and 2016. Age, sex, performance status, lung function, surgical approach, type of lung resection, complications, in-hospital and 30- and 90-day deaths and long-term survival were analysed.
    Results: Two hundred and fifty-seven patients were enrolled. The median age was 82 years (range 80-97). One hundred and thirty-four patients were treated by thoracotomy and 123 by video-assisted thoracic surgery [10 (8.1%) converted]. Two hundred and thirty-two underwent lobar resection and 25 underwent sublobar resection. There were no intraoperative deaths and 9 admissions to the intensive therapy unit; 112 (43.6%) patients suffered complications: More complications occurred after lobar versus after sublobar resections [45.7% vs 24% (P = 0.037)] and in those with chronic obstructive pulmonary disease (COPD) [57.4% vs 40% (P = 0.02)]. The 30-day mortality was 3.9% (n = 10) and the 90-day mortality was 6.22% (n = 16). One hundred and sixty-seven patients died during the study period; patients with non-small-cell lung cancer (n = 233) had a median survival of 46.5 months with 67.2% alive at 2 years and 40.8% at 5 years. Pathological stage and R status were independent prognostic factors for survival.
    Conclusions: Surgery for malignancies in octogenarians is feasible and safe with good long-term outcomes. The risk of postoperative complications, especially in those with COPD, is high but can be minimized with sublobar resection. Postoperative mortality is acceptable, and long-term survival is primarily governed by lung cancer stage. Age is no reason to deny patients surgery for early-stage disease.
    MeSH term(s) Aged, 80 and over ; Carcinoma, Non-Small-Cell Lung ; Humans ; Lung Neoplasms ; Neoplasm Staging ; Octogenarians ; Pneumonectomy/adverse effects ; Retrospective Studies ; Reward ; Thoracic Surgery, Video-Assisted/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2021-10-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2095298-3
    ISSN 1569-9285 ; 1569-9293
    ISSN (online) 1569-9285
    ISSN 1569-9293
    DOI 10.1093/icvts/ivab194
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Treatment of advanced peripheral arterial insufficiency in the elderly.

    Primc, Davor / Ivančić, Aldo / Saftić, Igor / Apanjol, Josip / Primcs, Ana Fućak / Lekić, Andrica

    Collegium antropologicum

    2015  Volume 39, Issue 1, Page(s) 67–70

    Abstract: Peripheral arterial insufficiency appears at all stages regardless of the patient age; however its appearance is most common in the elderly in which cases it mostly appears as stage described by Fontaine as stage III or IV The most com- mon cause of ... ...

    Abstract Peripheral arterial insufficiency appears at all stages regardless of the patient age; however its appearance is most common in the elderly in which cases it mostly appears as stage described by Fontaine as stage III or IV The most com- mon cause of peripheral arterial insufficiency is atherosclerotic degeneration, and is remarkably often accompanied by the diabetes. In the years 2012 and 2013 department of vascular surgery, University Hospital Rijeka admitted 169 patients older than 70 with peripheral arterial insufficiency of type Fontaine III and IV That number represents 68.8% of total number of patients admitted for peripheral arterial insufficiency. The goal of this research is to identify to what extent and in what percentage can patients older than 70 with advanced peripheral arterial insufficiency be subjected to vascular treatment and if there exist and absolute indication for angiographic treatment of such patients. In majority of patients, 148 of them, three or more comorbidities were present. Diabetes was present at almost half of patients, to be exact 46.7%. Assessment of possibility for vascular treatment and the need for angiographic treatment was followed in patients in three age groups: 70-75 years of age, 76-80 years of age and over 80 years of age. Angiography was performed on 69 patients and the insight into angiographic finding resulted in only 33 patients being subjected to some type of vascular treatment. From the total number of patient's subjected to vascular treatment 20 had symptoms of Fontaine III while the remaining 13 had symptoms of Fontaine IV Amputation procedure was performed 119 times. The research shows that angiograph- ic treatment is not a routine treatment in mentioned patients and that the number of vascular procedures is significantly higher in the 70-75 years age group.
    MeSH term(s) Aged ; Aged, 80 and over ; Angiography ; Arteries/physiopathology ; Atherosclerosis/complications ; Comorbidity ; Diabetes Complications ; Female ; Hospitalization ; Humans ; Intermittent Claudication/physiopathology ; Intermittent Claudication/therapy ; Male ; Peripheral Arterial Disease/physiopathology ; Peripheral Arterial Disease/therapy ; Vascular Diseases/therapy
    Language English
    Publishing date 2015-03
    Publishing country Croatia
    Document type Journal Article
    ZDB-ID 233430-6
    ISSN 0350-6134 ; 0353-3735
    ISSN 0350-6134 ; 0353-3735
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  5. Article: Polytrauma in elderly.

    Grzalja, Nikola / Saftić, Igor / Marinović, Marin / Stiglić, Damir / Cicvarić, Tiedi

    Collegium antropologicum

    2011  Volume 35 Suppl 2, Page(s) 231–234

    Abstract: The aim of this study is to present certain particularities in treating polytraumatized patients age of 65 and above. All of the patients were treated in our hospital. 413 patients were included in this 4 year study (2006-2010). Injury severity score was ...

    Abstract The aim of this study is to present certain particularities in treating polytraumatized patients age of 65 and above. All of the patients were treated in our hospital. 413 patients were included in this 4 year study (2006-2010). Injury severity score was 17 and above (ISS > 17). Patients aged above 65 were sub grouped. In this 4-year period, we treated 52 or 13% elderly patients. In this subgroup there were 30 (58%) males and 22 (42%) females, with mean age of 74 (max age 95 years old). Demographic factors, injury mechanisms, patients resuscitation protocols, imaging used, etc. were also included as variables. Mortality rate in elderly patients was 31%, while in patients below 65 years of age as 12%. Taking relevant data into consideration, a special emphasis was given to certain circumstances of intensive and surgical treatment of elderly patients. A large portion of polytraumatized patients are consisted of elderly. Patients aged 65 and above have higher mortality rate with lower ISS in the mortal group and falls are the most frequent mechanism of trauma. In this study, we tried to emphasize some clinical implications when treating those patients, as well as importance in continuous medical staff education in trauma principles to minimize mortality rates.
    MeSH term(s) Accidental Falls/mortality ; Adolescent ; Adult ; Age Distribution ; Aged ; Aged, 80 and over ; Croatia/epidemiology ; Emergency Service, Hospital/statistics & numerical data ; Female ; Humans ; Male ; Middle Aged ; Multiple Trauma/mortality ; Trauma Severity Indices ; Young Adult
    Language English
    Publishing date 2011-09
    Publishing country Croatia
    Document type Journal Article
    ZDB-ID 233430-6
    ISSN 0350-6134 ; 0353-3735
    ISSN 0350-6134 ; 0353-3735
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Off-pump versus on-pump--intermittent aortic cross clamping--myocardial revascularisation: single center expirience.

    Medved, Igor / Anić, Darko / Zrnić, Boris / Ostrić, Marin / Saftić, Igor

    Collegium antropologicum

    2008  Volume 32, Issue 2, Page(s) 381–384

    Abstract: The aim of this randomised, prospective study was to evaluate hospital mortality and morbidity after myocardial revascularisation, comparing on-pump coronary artery bypass graft (CABG) myocardial revascularisation versus off-pump coronary artery bypass ... ...

    Abstract The aim of this randomised, prospective study was to evaluate hospital mortality and morbidity after myocardial revascularisation, comparing on-pump coronary artery bypass graft (CABG) myocardial revascularisation versus off-pump coronary artery bypass graft (OPCAB) myocardial revascularisation in population with multivessels coronary artery disease. Sixty patients with multivessels coronary artery diseases were scheduled to undergo coronary artery bypass grafting from January 15, 2006 to June 30, 2007 in our institution. Patients were randomized to off-pump or on-pump surgery with intermittent cross-clamping of aorta and ventricular fibrillation, using the envelope method with random numbers. In the results only difference we did find postoperatively was in Creatine Kinase-MB (CK-MB) release, the amount of bleeding and intensive care unit (ICU) stay (p<0.05). There was no diference between the two groups of patients regarding incidence of main morbidity and hospital moratlity. In summary, we didn't find no superiority in any of the two techniques regarding on hospital mortality and morbidity.
    MeSH term(s) Aorta ; Constriction ; Coronary Artery Bypass/adverse effects ; Coronary Artery Bypass, Off-Pump/adverse effects ; Creatine Kinase, MB Form/blood ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Postoperative Complications ; Ventricular Fibrillation/etiology
    Chemical Substances Creatine Kinase, MB Form (EC 2.7.3.2)
    Language English
    Publishing date 2008-06
    Publishing country Croatia
    Document type Comparative Study ; Journal Article ; Randomized Controlled Trial
    ZDB-ID 233430-6
    ISSN 0350-6134 ; 0353-3735
    ISSN 0350-6134 ; 0353-3735
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Initial experience with external thoracic stabilization by the "figure of eight" osteosynthesis in polytraumatized patients with flail chest injury.

    Ivancić, Aldo / Saftić, Igor / Cicvarić, Tedi / Spanjol, Josip / Stalekar, Hrvoje / Marinović, Marin / Markić, Dean

    Collegium antropologicum

    2009  Volume 33, Issue 1, Page(s) 51–56

    Abstract: The aim of this study was to describe initial experience with external thoracic stabilization by the "figure of eight" osteosynthesis in polytraumatized patients with flail chest injury. From January 2002, fifteen patients underwent this surgical ... ...

    Abstract The aim of this study was to describe initial experience with external thoracic stabilization by the "figure of eight" osteosynthesis in polytraumatized patients with flail chest injury. From January 2002, fifteen patients underwent this surgical procedure at the University Hospital of Rijeka. Their mean age was 52 +/- 13.69 (range 18-65) and mean ISS was 29.8 (range: 20-41). Twelve patients were weaned from artificial respiration on same day when operated, two on the post-operative day 1, and one on the post-operative day 2. Their stay within the intensive care unit following extubation was within the range of 1-12 days (mean 3.93 +/- 2.99). The early external thoracic stabilization by the "figure of eight" osteosynthesis was followed by swift extubation of patient and direct normalization of respiratory parameters. This method contributed significantly to patient's shorter stay within the intensive care unit.
    MeSH term(s) Adolescent ; Adult ; Aged ; Female ; Flail Chest/surgery ; Fracture Fixation, Internal/methods ; Humans ; Length of Stay ; Male ; Middle Aged ; Respiration, Artificial
    Language English
    Publishing date 2009-03
    Publishing country Croatia
    Document type Journal Article
    ZDB-ID 233430-6
    ISSN 0350-6134 ; 0353-3735
    ISSN 0350-6134 ; 0353-3735
    Database MEDical Literature Analysis and Retrieval System OnLINE

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