Article: Evaluation of multi-component interventions for prevention of nosocomial pneumonia in older adults: a randomized, controlled trial.
2021 Volume 12, Issue 5, Page(s) 1045–1055
Abstract: Aims: To evaluate the efficacy of multi-component interventions for prevention of hospital-acquired pneumonia in older patients hospitalized in geriatric wards.: Methods: A randomized, parallel-group, controlled trial was undertaken in patients aged ... ...
| Abstract | Aims: To evaluate the efficacy of multi-component interventions for prevention of hospital-acquired pneumonia in older patients hospitalized in geriatric wards. Methods: A randomized, parallel-group, controlled trial was undertaken in patients aged 65 and above who were admitted to a tertiary hospital geriatric unit from January 1, 2016 to June 30, 2018 for an acute non-respiratory illness. Participants were randomized by to receive either a multi-component intervention (consisting of reverse Trendelenburg position, dysphagia screening, oral care and vaccinations), or usual care. The outcome measures were the proportion of patients who developed hospital-acquired pneumonia during hospitalisation, and mean time from randomization to the next hospitalisation due to respiratory infections in 1 year. Results: A total of 123 participants (median age, 85; 43.1% male) were randomized, (n = 59) to intervention group and (n = 64) to control group. The multi-component interventions did not significantly reduce the incidence of hospital-acquired pneumonia but did increase the mean time to next hospitalisation due to respiratory infection (11.5 months vs. 9.5 months; P = 0.049), and reduced the risk of hospitalisation in 1 year (18.6% vs. 34.4%; P = 0.049). Implementation of multi-component interventions increased diagnoses of oropharyngeal dysphagia (35.6% vs. 20.3%; P < 0.001) and improved the influenza (54.5% vs 17.2%; P < 0.001) and pneumococcal vaccination rates (52.5% vs. 20.3%; P < 0.001). Conclusions: The nosocomial pneumonia multi-component intervention did not significantly reduce the incidence of hospital-acquired pneumonia during hospitalisation but reduce subsequent hospitalisations for respiratory infections. Clinical trial registration: ClinicalTrial.gov, NCT04347395. |
|---|---|
| MeSH term(s) | Aged ; Aged, 80 and over ; COVID-19 ; Cross Infection/epidemiology ; Female ; Healthcare-Associated Pneumonia/epidemiology ; Humans ; Male ; SARS-CoV-2 ; Treatment Outcome |
| Language | English |
| Publishing date | 2021-06-03 |
| Publishing country | Switzerland |
| Document type | Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't |
| ZDB-ID | 2556794-9 |
| ISSN | 1878-7657 ; 1878-7649 |
| ISSN (online) | 1878-7657 |
| ISSN | 1878-7649 |
| DOI | 10.1007/s41999-021-00506-3 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
Full text online
More links
Kategorien
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.