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Article: Factors Influencing the Outcome of Spontaneous Healing of Traumatic Tympanic Membrane Perforation: A Clinical Prospective Observational Study.

Bishnoi, Tapasya / Marlapudi, Sudheer Kumar / Sahu, P K

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

2023 Volume 75, Issue 3, Page(s) 1774–1781

Abstract: Trauma to the ear is typically attributed to its location in the craniofacial skeleton. TM is prone to rupture, tear, or perforation when traumatized. Etiological factors may be classified according to the pathogenetic mechanisms (air-pressure change, ... ...

Abstract	Trauma to the ear is typically attributed to its location in the craniofacial skeleton. TM is prone to rupture, tear, or perforation when traumatized. Etiological factors may be classified according to the pathogenetic mechanisms (air-pressure change, heat, solids, water pressure). Materials & method: This is a prospective study of 70 patients with traumatic tympanic membrane perforation between January 2019 and December 2022. Inclusion and exclusion criteria applied and results interpreted. Results: Traumatic TM affects all age groups with a mean age of 27.94 ± 4.76 years. Traumatic TM affects all age groups with a mean age of 27.94 ± 4.76 years, with the highest incidence among the middle-aged groups 61.4%. The male-to-female ratio was found to be 1.9:1, with high predominance among male patients (65.7%) with a frequency of 57.1% for slap injury group in our study contrary to others. Spontaneous healing was observed in 88.6% over a follow-up period of 12 weeks in this study. Our study has not shown that associated comorbidities influence healing ( Conclusion: There is a high predominance of TM perforation among male patients in our study may be attributed to activity. Spontaneous healing is more common. Duration of healing was significantly affected by the size of the perforation with longer duration for large perforations and vice versa. It is observed in this study that the duration of spontaneous healing is longer in blast injuries when compared to other kinds of injuries. A significant proportion of marginal perforations that have not healed in our study may be attributed to annular ligament involvement.
Language	English
Publishing date	2023-04-08
Publishing country	India
Document type	Journal Article
ZDB-ID	1471137-0
ISSN	0973-7707 ; 2231-3796 ; 0019-5421
ISSN (online)	0973-7707
ISSN	2231-3796 ; 0019-5421
DOI	10.1007/s12070-023-03722-4
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Article: Common Tumor in an uncommon location: Pleomorphic Adenoma of nasal cavity - a case Report.

Marlapudi, Sudheer Kumar / Bishnoi, Tapasya / Sahu, P K / Kumar, Praveen

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

2023 Volume 75, Issue Suppl 1, Page(s) 947–950

Abstract: Pleomorphic adenoma (PA) is the most common benign salivary gland tumor of which parotid gland involvement is the most common. PA may arise from minor salivary glands as well, however, PA is very rare in the sinonasal and nasopharyngeal areas. It usually ...

Abstract	Pleomorphic adenoma (PA) is the most common benign salivary gland tumor of which parotid gland involvement is the most common. PA may arise from minor salivary glands as well, however, PA is very rare in the sinonasal and nasopharyngeal areas. It usually affects middle aged females. They are frequently misdiagnosed due to high cellularity and myxoid stroma, leading to delay in diagnosis & further appropriate management. Here we present a case report of a female who presented with gradually progressive nasal obstruction, on examination found to have a nasal mass in right nasal cavity. Imaging was done and the nasal mass was excised. Histopathological report revealed a PA. Common tumor in an uncommon location: Pleomorphic adenoma of the nasal cavity - a case report.
Language	English
Publishing date	2023-02-04
Publishing country	India
Document type	Journal Article
ZDB-ID	1471137-0
ISSN	0973-7707 ; 2231-3796 ; 0019-5421
ISSN (online)	0973-7707
ISSN	2231-3796 ; 0019-5421
DOI	10.1007/s12070-022-03446-x
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Article: Bipaddle Pectoralis Major Myocutaneous Flap for Single Stage Reconstruction of Oromandibular Defects.

Sahu, P K / Kumar, Satish

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

2019 Volume 72, Issue 1, Page(s) 44–48

Abstract: Reconstruction of full thickness defects after resection of oral cancer is a challenge. Although microvascular free flaps are considered the first choice, their use is limited in the developing regions by availability of resources and the expertise. In ... ...

Abstract	Reconstruction of full thickness defects after resection of oral cancer is a challenge. Although microvascular free flaps are considered the first choice, their use is limited in the developing regions by availability of resources and the expertise. In this study, we have presented our experience with the use of bipaddle pectoralis major myocutaneous (PMMC) flap as a single stage reconstruction option for defects of the oral cavity. After undergoing resection of oral cancer, 12 patients with full thickness defects of the oral cavity were reconstructed using bipaddle/bilobed/double-island/folded PMMC flap in a single stage procedure. The results of PMMC flaps were studied. All the patients had through and through defects of oral cavity, which were reconstructed in a single stage surgery using bipaddle PMMC flap. The overall complication rate was 33.33%, however, there were no cases of total flap necrosis. The mean time of reconstruction was 141.25 min with average hospital stay of 18.5 days. PMMC flap is a versatile flap with dedicated blood supply, good bulk and great reach. With limited availability of resources, it can be used as a single stage reconstruction technique in oral cavity defects with good results.
Language	English
Publishing date	2019-08-19
Publishing country	India
Document type	Journal Article
ZDB-ID	1471137-0
ISSN	0973-7707 ; 2231-3796 ; 0019-5421
ISSN (online)	0973-7707
ISSN	2231-3796 ; 0019-5421
DOI	10.1007/s12070-019-01731-w
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Article: Epidemiological Aspects of Oral Cancer in North Indian Population.

Sahu, P K / Kumar, Satish

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

2019 Volume 71, Issue Suppl 1, Page(s) 944–948

Abstract: Introduction: Head and neck cancers are common in the developing nations, especially in the south-east Asia. They account for the commonest malignancy type in India and pose a major public health concern. Oral cancer is the commonest of all head and ... ...

Abstract	Introduction: Head and neck cancers are common in the developing nations, especially in the south-east Asia. They account for the commonest malignancy type in India and pose a major public health concern. Oral cancer is the commonest of all head and neck malignancies. Material and methods: It is a prospective study done from January 2017 to July 2018 at a tertiary care centre with patient population ranging from 22 to 87 years of age. All the 128 patients, irrespective of their gender, with a proven malignancy of the oral cavity were observed for various epidemiological and disease characteristics. Results: Oral cavity cancers were more common in males than females. It is prevalent in the age group of 60-70 years. The most common site of involvement is the buccal mucosa followed by the tongue. Tobacco chewing and smoking is the most significant risk factor associated. The most commonly involved neck nodes are level I and II lymph nodes. Conclusion: Oral cancers are common in Indian population. It presents at advanced stage due to poor socioeconomic status of the patients. However, it has also been seen in younger population owing to increasing use of tobacco products. Preventive strategy, based on the epidemiological characteristics, is the need of the hour to reduce the disease burden.
Language	English
Publishing date	2019-03-14
Publishing country	India
Document type	Journal Article
ZDB-ID	1471137-0
ISSN	0973-7707 ; 2231-3796 ; 0019-5421
ISSN (online)	0973-7707
ISSN	2231-3796 ; 0019-5421
DOI	10.1007/s12070-019-01629-7
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Article: Aloe vera Based Dipping Treatments on Shelf Life and Physico-Chemical Properties of Litchi During Ambient Storage

Mani, Arghya / Sharangi, A. B. / Sahu, P. K.

Proceedings of the National Academy of Sciences, India, Section B: biological sciences. 2021 Sept., v. 91, no. 3

2021

Abstract: Litchi exhibits very limited postharvest life due to rapid softening and decay in spite of being a non-climacteric fruit. After the 3rd day onwards the fruit shows cracking and browning of skin. Litchi fruits after harvesting were dipped with Aloe vera ... ...

Abstract	Litchi exhibits very limited postharvest life due to rapid softening and decay in spite of being a non-climacteric fruit. After the 3rd day onwards the fruit shows cracking and browning of skin. Litchi fruits after harvesting were dipped with Aloe vera and different safe products like chitosan, corn starch calcium chloride and salicylic acid. A treatment of Aloe vera 50% + Chitosan 2% was able to reduce the PLW of litchi fruits up to eighth day of storage, exhibited minimum shrinkage of the fruits, minimum change in total sugar content and titratable acidity of the fruits during 8th day of storage. Aloe vera 50% + Chitosan 1% successfully reduced the rate of increase in TSS of the fruits even up to 8th day of storage. Least change in vitamin C content during storage was observed in Aloe vera 50% + Chitosan 1% followed by Aloe vera 50% + Chitosan 2%. The same treatment reduced the incidence of fruit cracking, skin browning and decay percentage. No drastic change in organoleptic property was observed during the storage period. Hence the treatment of litchi with Aloe vera and chitosan can enhance non-refrigerated storage life of litchi up to 8 days.
Keywords	Aloe vera ; Litchi ; ascorbic acid ; calcium chloride ; chitosan ; corn starch ; non-climacteric fruits ; salicylic acid ; shelf life ; shrinkage ; storage time ; sugar content ; titratable acidity ; India
Language	English
Dates of publication	2021-09
Size	p. 521-532.
Publishing place	Springer India
Document type	Article
ZDB-ID	2707745-7
ISSN	2250-1746 ; 0369-8211
ISSN (online)	2250-1746
ISSN	0369-8211
DOI	10.1007/s40011-021-01248-9
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Article ; Online: P and T wave detection and delineation of ECG signal using differential evolution (DE) optimization strategy.

Panigrahy, D / Sahu, P K

Australasian physical & engineering sciences in medicine

2018 Volume 41, Issue 1, Page(s) 225–241

Abstract: Generally, P and T waves in an electrocardiogram (ECG) signal are lower in amplitude compared to amplitude of QRS complex and contaminated with noises from various sources. Due to these problems and lack of universal delineation rule, the automated ... ...

Abstract	Generally, P and T waves in an electrocardiogram (ECG) signal are lower in amplitude compared to amplitude of QRS complex and contaminated with noises from various sources. Due to these problems and lack of universal delineation rule, the automated detection and delineation of T and P waves (on, off, and peak position of T and P wave) in the ECG signal are challenging task. The effectiveness for detection of on, off, and peak position of T and P wave by using differential evolution (DE) algorithm with the denoising technique has been verified in this manuscript. The denoising operation of the ECG signal has been performed by extended Kalman smoother (EKS) framework. DE algorithm is used for selection of optimized width and phase of five waves of the ECG signal. These parameters are used in EKS for initialization of the process noise covariance matrix and also development of the state equation. The new algorithm (an intelligent process of searching and subtraction) for detection of on, off and peak location of P and T waves without using amplitude threshold is developed by using the optimized parameters computed by the DE algorithm and denoised ECG signal with the help of the EKS framework. The effectiveness of the proposed technique has been validated using real-time QT database. Our proposed method shows better sensitivity, predicitvity and accuracy compared to other well-known methods for detection of on, off, peak location of P and T wave.
MeSH term(s)	Algorithms ; Artifacts ; Databases as Topic ; Electrocardiography ; Humans ; Signal Processing, Computer-Assisted ; Signal-To-Noise Ratio
Language	English
Publishing date	2018-02-26
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	46226-3
ISSN	1879-5447 ; 0158-9938
ISSN (online)	1879-5447
ISSN	0158-9938
DOI	10.1007/s13246-018-0629-8
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Article ; Online: Extraction of fetal ECG signal by an improved method using extended Kalman smoother framework from single channel abdominal ECG signal.

Panigrahy, D / Sahu, P K

Australasian physical & engineering sciences in medicine

2017 Volume 40, Issue 1, Page(s) 191–207

Abstract: This paper proposes a five-stage based methodology to extract the fetal electrocardiogram (FECG) from the single channel abdominal ECG using differential evolution (DE) algorithm, extended Kalman smoother (EKS) and adaptive neuro fuzzy inference system ( ... ...

Abstract	This paper proposes a five-stage based methodology to extract the fetal electrocardiogram (FECG) from the single channel abdominal ECG using differential evolution (DE) algorithm, extended Kalman smoother (EKS) and adaptive neuro fuzzy inference system (ANFIS) framework. The heart rate of the fetus can easily be detected after estimation of the fetal ECG signal. The abdominal ECG signal contains fetal ECG signal, maternal ECG component, and noise. To estimate the fetal ECG signal from the abdominal ECG signal, removal of the noise and the maternal ECG component presented in it is necessary. The pre-processing stage is used to remove the noise from the abdominal ECG signal. The EKS framework is used to estimate the maternal ECG signal from the abdominal ECG signal. The optimized parameters of the maternal ECG components are required to develop the state and measurement equation of the EKS framework. These optimized maternal ECG parameters are selected by the differential evolution algorithm. The relationship between the maternal ECG signal and the available maternal ECG component in the abdominal ECG signal is nonlinear. To estimate the actual maternal ECG component present in the abdominal ECG signal and also to recognize this nonlinear relationship the ANFIS is used. Inputs to the ANFIS framework are the output of EKS and the pre-processed abdominal ECG signal. The fetal ECG signal is computed by subtracting the output of ANFIS from the pre-processed abdominal ECG signal. Non-invasive fetal ECG database and set A of 2013 physionet/computing in cardiology challenge database (PCDB) are used for validation of the proposed methodology. The proposed methodology shows a sensitivity of 94.21%, accuracy of 90.66%, and positive predictive value of 96.05% from the non-invasive fetal ECG database. The proposed methodology also shows a sensitivity of 91.47%, accuracy of 84.89%, and positive predictive value of 92.18% from the set A of PCDB.
MeSH term(s)	Algorithms ; Databases as Topic ; Electrocardiography ; Female ; Fetus/physiology ; Fuzzy Logic ; Humans ; Pregnancy ; Signal Processing, Computer-Assisted
Language	English
Publishing date	2017-03
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	46226-3
ISSN	1879-5447 ; 0158-9938
ISSN (online)	1879-5447
ISSN	0158-9938
DOI	10.1007/s13246-017-0527-5
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Article ; Online: Captopril is more effective than Perindopril against aluminium chloride induced amyloidogenesis and AD like pathology

Mohapatra, Debashish / Kanungo, Srikant / Pradhan, Sweta Priyadarshini / Jena, Susmita / Prusty, Shakti Ketan / Sahu, P. K.

Heliyon. 2022 Feb., v. 8, no. 2 p.e08935-

2022

Abstract: Alzheimer's disease (AD) is a common neurodegenerative disorder. Aluminium chloride induces AD like pathology in rats. Renin angiotensin system plays a significant role in the pathogenesis and occurrence of Alzheimer's disease. In the present study we ... ...

Abstract	Alzheimer's disease (AD) is a common neurodegenerative disorder. Aluminium chloride induces AD like pathology in rats. Renin angiotensin system plays a significant role in the pathogenesis and occurrence of Alzheimer's disease. In the present study we evaluated and compared the effect of Captopril and Perindopril against aluminium chloride induced amyloidogenesis and cognitive dysfunction in rats. Wistar rats of both sex were divided randomly into four groups i.e. Group I was served as normal control and treated with normal saline, Group II was administered with AlCl₃ (100 mg/kg, p. o.) and Group III and IV received Captopril (30 mg/kg, p. o.) and Perindopril (5 mg/kg, p. o.) respectively 1hr prior to administration of AlCl₃. All the doses were given once daily for 42 days. The evaluation of memory function was carried out in Y-maze (spontaneous alternation), radial arm maze (number of correct responses) and elevated plus maze (transfer latency). After behavioral studies, estimation of antioxidant status (brain and serum), amyloid-β content (brain) and histopathology of brain hippocampus region was done. Administration of AlCl₃ for 42 days impaired cognitive dysfunction. Captopril and Perindopril prevented AlCl₃ induced cognitive dysfunction by improving spontaneous alternation behavior, number of correct responses and reducing transfer latency. They also increase the antioxidant status, reduce the Aβ42 content in the brain and reverse the histopathological changes caused by AlCl₃ in hippocampal region. Both Captopril and Perindopril protects against aluminium chloride induced amyloidogenesis and AD like pathology. Captopril is found to be more effective than Perindopril.
Keywords	Alzheimer disease ; aluminum chloride ; antioxidants ; blood serum ; cognitive disorders ; hippocampus ; histopathology ; memory ; neurodegenerative diseases ; pathogenesis ; renin ; Amyloid-β ; Oxidative stress ; ACE ; Rennin angiotensin system
Language	English
Dates of publication	2022-02
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Use and reproduction
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2022.e08935
Database	NAL-Catalogue (AGRICOLA)

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Article: A Study of Otological Manifestations of Temporal Bone Fractures.

Prasad, B K / Basu, A / Sahu, P K / Rai, A K

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

2020 Volume 74, Issue Suppl 1, Page(s) 351–359

Abstract: The aim of study was to evaluate various otological manifestations of temporal bone fractures and to suggest their management. This prospective observational study was conducted in a tertiary care hospital of Armed Forces over 2.5 years in 57 cases of ... ...

Abstract	The aim of study was to evaluate various otological manifestations of temporal bone fractures and to suggest their management. This prospective observational study was conducted in a tertiary care hospital of Armed Forces over 2.5 years in 57 cases of temporal bone fracture in patients of age group of 12-59 yrs comprising 49 males and 8 females. Radioimaging was done for diagnosing the fracture, mapping its extent and for clinical correlation. Hearing was assessed by tuning forks, free field hearing and pure tone audiogram as per the fitness of patient. Majority of patients were in the age group 20-40 years who had met with road accidents. Important otological features included Battle sign (24.6%), ear canal laceration (53%), tympanic membrane perforation (7%), haemotymanum (40%), ear discharge (66.7%), hearing loss (63%), vertigo (16%), tinnitus (21%), facial paralysis (68%) and cerebrospinal fluid otorrhea (3.5%). Otic capsule sparing fracture was three times more common than violating ones. Facial palsies were treated with oral steroid with complete recovery in 56.41% cases but three required decompression surgery. 4 patients underwent tympanoplasty. Both the cerebrospinal fluid leaks stopped in 2 weeks time. Facial palsy is as common as hearing loss. TM perforation is as rare as CSF leak. Otic capsule violating fracture line is less common. Hearing loss shows recovery in most of the cases. Delayed onset positional vertigo is more common than acute vertigo. Large numbers of immediate onset complete facial palsy do recover from injury without surgery.
Language	English
Publishing date	2020-09-11
Publishing country	India
Document type	Journal Article
ZDB-ID	1471137-0
ISSN	0973-7707 ; 2231-3796 ; 0019-5421
ISSN (online)	0973-7707
ISSN	2231-3796 ; 0019-5421
DOI	10.1007/s12070-020-02111-5
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Article: Flow behind an exponential shock wave in a rotational axisymmetric perfect gas with magnetic field and variable density.

Nath, G / Sahu, P K

SpringerPlus

2016 Volume 5, Issue 1, Page(s) 1509

Abstract: A self-similar model for one-dimensional unsteady isothermal and adiabatic flows behind a strong exponential shock wave driven out by a cylindrical piston moving with time according to an exponential law in an ideal gas in the presence of azimuthal ... ...

Abstract	A self-similar model for one-dimensional unsteady isothermal and adiabatic flows behind a strong exponential shock wave driven out by a cylindrical piston moving with time according to an exponential law in an ideal gas in the presence of azimuthal magnetic field and variable density is discussed in a rotating atmosphere. The ambient medium is assumed to possess radial, axial and azimuthal component of fluid velocities. The initial density, the fluid velocities and magnetic field of the ambient medium are assumed to be varying with time according to an exponential law. The gas is taken to be non-viscous having infinite electrical conductivity. Solutions are obtained, in both the cases, when the flow between the shock and the piston is isothermal or adiabatic by taking into account the components of vorticity vector. The effects of the variation of the initial density index, adiabatic exponent of the gas and the Alfven-Mach number on the flow-field behind the shock wave are investigated. It is found that the presence of the magnetic field have decaying effects on the shock wave. Also, it is observed that the effect of an increase in the magnetic field strength is more impressive in the case of adiabatic flow than in the case of isothermal flow. The assumption of zero temperature gradient brings a profound change in the density, non-dimensional azimuthal and axial components of vorticity vector distributions in comparison to those in the case of adiabatic flow. A comparison is made between isothermal and adiabatic flows. It is obtained that an increase in the initial density variation index, adiabatic exponent and strength of the magnetic field decrease the shock strength.
Language	English
Publishing date	2016-09-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2661116-8
ISSN	2193-1801
ISSN	2193-1801
DOI	10.1186/s40064-016-3119-z
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