Article ; Online: Developmental alcohol exposure is exhausting: Sleep and the enduring consequences of alcohol exposure during development.
Neuroscience and biobehavioral reviews
2024 Volume 158, Page(s) 105567
Abstract: Prenatal alcohol exposure is the leading nongenetic cause of human intellectual impairment. The long-term impacts of prenatal alcohol exposure on health and well-being are diverse, including neuropathology leading to behavioral, cognitive, and emotional ... ...
Abstract | Prenatal alcohol exposure is the leading nongenetic cause of human intellectual impairment. The long-term impacts of prenatal alcohol exposure on health and well-being are diverse, including neuropathology leading to behavioral, cognitive, and emotional impairments. Additionally negative effects also occur on the physiological level, such as the endocrine, cardiovascular, and immune systems. Among these diverse impacts is sleep disruption. In this review, we describe how prenatal alcohol exposure affects sleep, and potential mechanisms of those effects. Furthermore, we outline the evidence that sleep disruption across the lifespan may be a mediator of some cognitive and behavioral impacts of developmental alcohol exposure, and thus may represent a promising target for treatment. |
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MeSH term(s) | Female ; Humans ; Pregnancy ; Fetal Alcohol Spectrum Disorders/etiology ; Prenatal Exposure Delayed Effects ; Ethanol/adverse effects ; Sleep |
Chemical Substances | Ethanol (3K9958V90M) |
Language | English |
Publishing date | 2024-02-01 |
Publishing country | United States |
Document type | Journal Article ; Review |
ZDB-ID | 282464-4 |
ISSN | 1873-7528 ; 0149-7634 |
ISSN (online) | 1873-7528 |
ISSN | 0149-7634 |
DOI | 10.1016/j.neubiorev.2024.105567 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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