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Book: Ischias-Schmerzen selbst behandeln

Sakai, Shintaro / Quitterer, Birgit

Die erfolgreichen Methoden aus Japan für sich nutzen und endlich schmerzfrei werden

2023

Abstract: Der Bestseller aus Japan -- Der Ischiasnerv und das Iliosakralgelenk können vielfältige Probleme bereiten. Von Schmerzen oder Blockaden im unteren Rücken oder in den Beinen bis zu Taubheitsgefühlen oder gar Lähmungserscheinungen. Wenn auch Sie darunter ... ...

Author's details	Shintaro Sakai ist Chef der Sakai-Klinik und ärztlicher Berater der Baseballmannschaft Chiba Lotte Marines. Neben Erfahrungen in der orthopädischen Chirurgie und in einer Spezialklinik für Hüftleiden hat er eine praktische Ausbildung in Obduktion absolviert. Dadurch wurde er zu seiner Methode, das Innere der Gelenkkapsel zu heilen, inspiriert und konzentriert sich seitdem auf schwer behandelbare Knie-, Hüft-, Schulter- und Nackenleiden. Unter seinen Kunden sind viele Prominente, wie bekannte Sportler oder Schauspieler in Japan. Dort ist er auch in den Medien häufig vertreten und hat bereits zahlreiche Bücher geschrieben
Abstract	Der Bestseller aus Japan -- Der Ischiasnerv und das Iliosakralgelenk können vielfältige Probleme bereiten. Von Schmerzen oder Blockaden im unteren Rücken oder in den Beinen bis zu Taubheitsgefühlen oder gar Lähmungserscheinungen. Wenn auch Sie darunter leiden, dann ist dieses Buch genau das Richtige für Sie. Dr. Shintaro Sakai, der in Japan für seine ungewöhnlichen Ansätze bekannt ist, nimmt ihre Beschwerden ganzheitlich in den Blick und stellt Ihnen sein Programm bei Ischiasbeschwerden vor: ...
Keywords	Gesäß ; Gesäßschmerzen ; Iliosakralgelenk ; Iliosakralgelenk Übungen ; Ischias ; Ischias Schlafposition ; Ischias Schmerzen ; Ischiasbeschwerden ; Ischiasnerv ; Ischiasnerv Verlauf ; Ischiasschmerzen ; Lumboischialgie ; Lähmungserscheinung ; Nerv ; Schmerzen in den Beinen ; Schmerzen unterer Rücken ; Taubheitsgefühl ; Wundermittel Ischias
Language	German
Size	96 p.
Edition	1
Publisher	Trias
Document type	Book
Note	PDA Manuell_24
Format	158 x 217 x 9
ISBN	9783432117881 ; 3432117884
Database	PDA

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Book: Arthrose im Knie selbst behandeln

Sakai, Shintarō / Quitterer, Birgit

die erfolgreichen Methoden aus Japan für sich nutzen und endlich schmerzfrei werden

2022

Title translation	Henkeisei hizakansetsu-sho wa jibun de naoseru!
Author's details	Shintaro Sakai ; aus dem Japanischen von Birgit Quitterer
Keywords	Knie ; Kniegelenk ; Selbstbehandlung ; Selbsttest ; Arthrose ; Kniearthrose ; Kniegelenkarthrose ; Knieleiden ; Kniemassage ; Knieproblem ; Knieschmerzen ; Knieübung ; Dehnung ; Dehnübung ; Gelenkkapsel ; 600
Subject	Stretching ; Dehngymnastik ; Dehnungsübung ; Dehnübungen ; Kniegelenksarthrose ; Gonarthrose ; Gonarthrosis deformans ; Kniearthrose
Language	German
Size	90 Seiten, Illustrationen, 21.7 cm x 16 cm
Edition	1. Auflage
Publisher	TRIAS
Publishing place	Stuttgart
Publishing country	Germany
Document type	Book
HBZ-ID	HT021289358
ISBN	978-3-432-11348-7 ; 3-432-11348-X ; 9783432113494 ; 3432113498
Database	Catalogue ZB MED Medicine, Health

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Article ; Online: Evolution of mixed mating: Effects of among-parent variation in early-acting inbreeding depression coupled with overproduction of ovules.

Sakai, Satoki

Journal of theoretical biology

2022 Volume 550, Page(s) 111241

Abstract: Theoretical models were developed to propose a new mechanism enhancing mixed mating (reproduction by both outcrossing and selfing) in hermaphroditic plants; mixed mating can be maintained if there exists among-parent variation in early-acting inbreeding ... ...

Abstract	Theoretical models were developed to propose a new mechanism enhancing mixed mating (reproduction by both outcrossing and selfing) in hermaphroditic plants; mixed mating can be maintained if there exists among-parent variation in early-acting inbreeding depression in embryos and parents can replace dead embryos by overproduction of ovules. In the two main models developed, the number of embryos produced is allowed to evolve, parents may overproduce embryos, and among-parent variation in early-acting inbreeding depression does not exist or exists. I found that mixed mating does not evolve if among-parent variation in early-acting inbreeding depression does not exist, whereas it evolves if it exists. If the degree of early-acting inbreeding depression in embryos is variable among parents, parents with the same selfing strategy suffer different effects of early-acting inbreeding depression. Specifically, overproduction of embryos may be insufficient when inbreeding depression is severe but wasteful when it is weak. Hence, it is advantageous to produce a moderate number of embryos to reduce waste of resources. Mixed mating is then advantageous to avoid great reductions in seed number caused by massive loss of selfed embryos in cases of severe inbreeding depression.
MeSH term(s)	Inbreeding ; Inbreeding Depression ; Ovule ; Plants ; Reproduction
Language	English
Publishing date	2022-08-05
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2972-5
ISSN	1095-8541 ; 0022-5193
ISSN (online)	1095-8541
ISSN	0022-5193
DOI	10.1016/j.jtbi.2022.111241
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Article ; Online: Why are deleterious mutations maintained in selfing populations? An analysis of the effects of early- and late-acting mutations by a two-locus two-allele model.

Sakai, Satoki

Journal of theoretical biology

2021 Volume 533, Page(s) 110956

Abstract: Frequencies of deleterious mutations are higher than expected in many plants. Here, by developing a two-locus two-allele model, I examine the effects of differential timing of the expression of deleterious mutations (two-stage effects) on the maintenance ...

Abstract	Frequencies of deleterious mutations are higher than expected in many plants. Here, by developing a two-locus two-allele model, I examine the effects of differential timing of the expression of deleterious mutations (two-stage effects) on the maintenance of mutations. I assume early- and late-acting loci to distinguish whether maintenance of mutations in populations with high selfing rates is explained better by two-stage effects of single mutations, or by separate mutations in both early- and late-acting loci. I found that, when ovules are overproduced, the stable frequency of early-acting mutations is higher if mutations also occur in a late-acting locus than if a late-acting mutation is lacking. The stable frequency of late-acting mutations is higher if mutations also occur in an early-acting locus than if an early-acting mutation is lacking. Selective interference does not account for these results because analyses in which the number of loci subject to mutations is equalized are included. Overproduction of ovules has little effect on maintenance if either early- or late-acting mutations are lacking, whereas when ovules are not overproduced, the two-stage effect does not enhance the maintenance of mutations. Hence, mutations occurring in both loci coupled with overproduction of ovules enhances the maintenance of mutations in populations with high selfing rates. The detailed mechanisms underlying the two-stage effect were also analyzed.
MeSH term(s)	Alleles ; Inbreeding ; Models, Genetic ; Mutation ; Selection, Genetic
Language	English
Publishing date	2021-11-02
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2972-5
ISSN	1095-8541 ; 0022-5193
ISSN (online)	1095-8541
ISSN	0022-5193
DOI	10.1016/j.jtbi.2021.110956
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Article ; Online: Effect of cell adhesiveness of Cell Dome shell on enclosed HeLa cells.

Kazama, Ryotaro / Sakai, Shinji

Journal of bioscience and bioengineering

2024 Volume 137, Issue 4, Page(s) 313–320

Abstract: The Cell Dome is a dome-shaped structure (diameter: 1 mm, height: 270 μm) with cells enclosed within a cavity, covered by a hemispherical hydrogel shell, and immobilized on a glass plate. Given that the cells within Cell Dome are in contact with the ... ...

Abstract	The Cell Dome is a dome-shaped structure (diameter: 1 mm, height: 270 μm) with cells enclosed within a cavity, covered by a hemispherical hydrogel shell, and immobilized on a glass plate. Given that the cells within Cell Dome are in contact with the inner walls of the hydrogel shell, the properties of the shell are anticipated to influence cell behavior. To date, the impact of the hydrogel shell properties on the enclosed cells has not been investigated. In this study, we explored the effects of the cell adhesiveness of hydrogel shell on the behavior of enclosed cancer cells. Hydrogel shells with varying degrees of cell adhesiveness were fabricated using aqueous solutions containing either an alginate derivative with phenolic hydroxyl moieties exclusively or a mixture of alginate and gelatin derivatives with phenolic hydroxyl moieties. Hydrogel formation was mediated by horseradish peroxidase. We used the HeLa human cervical cancer cell line, which expresses fucci2, a cell cycle marker, to observe cell behavior. Cells cultured in hydrogel shells with cell adhesiveness proliferated along the inner wall of the hydrogel shell. Conversely, cells in hydrogel shells without cell adhesiveness grew uniformly at the bottom of the cavities. Furthermore, cells in non-adhesive hydrogel shells had a higher percentage of cells in the G1/G0 phase compared to those in adhesive shells and exhibited increased resistance to mitomycin hydrochloride when the cavities became filled with cells. These results highlight the need to consider the cell adhesiveness of the hydrogel shell when selecting materials for constructing Cell Dome.
MeSH term(s)	Humans ; HeLa Cells ; Adhesiveness ; Hydrogels/chemistry ; Cell Adhesion ; Alginates/chemistry ; Gelatin/chemistry
Chemical Substances	Hydrogels ; Alginates ; Gelatin (9000-70-8)
Language	English
Publishing date	2024-02-01
Publishing country	Japan
Document type	Journal Article
ZDB-ID	1465387-4
ISSN	1347-4421 ; 1389-1723
ISSN (online)	1347-4421
ISSN	1389-1723
DOI	10.1016/j.jbiosc.2024.01.002
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Article: An Extended Kolmogorov-Avrami-Ishibashi (EKAI) Model to Simulate Dynamic Characteristics of Polycrystalline-Ferroelectric-Gate Field-Effect Transistors.

Sakai, Shigeki / Takahashi, Mitsue

Materials (Basel, Switzerland)

2024 Volume 17, Issue 5

Abstract: A physics-based model on polarization switching in ferroelectric polycrystalline films is proposed. The calculation results by the model agree well with experimental results regarding dynamic operations of ferroelectric-gate field-effect transistors ( ... ...

Abstract	A physics-based model on polarization switching in ferroelectric polycrystalline films is proposed. The calculation results by the model agree well with experimental results regarding dynamic operations of ferroelectric-gate field-effect transistors (FeFETs). In the model, an angle
Language	English
Publishing date	2024-02-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma17051077
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Article ; Online: Maintenance of high inbreeding depression in selfing populations: Two-stage effect of early- and late-acting mutations.

Sakai, Satoki

Journal of theoretical biology

2020 Volume 502, Page(s) 110307

Abstract: High estimates of inbreeding depression have been obtained in many plant populations with high selfing rates. However, deleterious mutations might be purged from such populations as a result of selfing. I developed a simulation model assuming the ... ...

Abstract	High estimates of inbreeding depression have been obtained in many plant populations with high selfing rates. However, deleterious mutations might be purged from such populations as a result of selfing. I developed a simulation model assuming the presence of mutations at two sets of loci, namely, early- and late-acting loci, and the selective abortion of embryos coupled with ovule overproduction. In the model, early-acting loci are expressed during embryo initiation, and less vigorous embryos are aborted. Late-acting loci are expressed after selective abortion ends; the surviving embryos (seeds) compete, and some of them form the next generation. If mutations are allowed to occur in both early- and late-acting loci, both types increase in frequency in populations with high selfing rates. However, this phenomenon does not occur if mutations occur only in the early- or only in the late-acting loci. Consistent results are observed even if the total number of loci in which mutations are allowed to occur is the same for simulations with both early- and late-acting loci, only early-acting loci, or only late-acting loci, indicating that the presence of both types of loci is the causal factor. Thus, the two-stage effect, or occurrence of both early- and late-acting mutations, promotes the maintenance of these mutations in populations with high selfing rates.
MeSH term(s)	Inbreeding ; Inbreeding Depression ; Mutation ; Plants ; Seeds
Language	English
Publishing date	2020-05-12
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2972-5
ISSN	1095-8541 ; 0022-5193
ISSN (online)	1095-8541
ISSN	0022-5193
DOI	10.1016/j.jtbi.2020.110307
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Intraspecific variation in morphology of spiny pollen grains along an altitudinal gradient in an insect-pollinated shrub.

Hasegawa, T M / Itagaki, T / Sakai, S

Plant biology (Stuttgart, Germany)

2022 Volume 25, Issue 2, Page(s) 287–295

Abstract: Intraspecific variations in pollen morphological traits are poorly studied. Interspecific variations are often associated with pollination systems and pollinator types. Altitudinal environmental changes, which can influence local pollinator assemblages, ... ...

Abstract	Intraspecific variations in pollen morphological traits are poorly studied. Interspecific variations are often associated with pollination systems and pollinator types. Altitudinal environmental changes, which can influence local pollinator assemblages, provide opportunities to explore differentiation in pollen traits of a single species over short distances. The aim of this study is to examine intraspecific variations in pollen traits of an insect-pollinated shrub, Weigela hortensis (Caprifoliaceae), along an altitudinal gradient. Pollen spine phenotypes (length, number and density), pollen diameter, lipid mass (pollenkitt) around pollen grains, pollen production per flower and pollinator assemblages were compared at four sites at different altitudes. Spine length and the spine length/diameter ratio of pollen grains were greater at higher altitudes but not correlated with flower or plant size. Spine number and density increased as flower size increased, and pollen lipid mass decreased as plant size increased. Bees were the predominant pollinators at low-altitude sites whereas flies, specifically Oligoneura spp. (Acroceridae), increased in relative abundance with increasing altitude. The results of this study suggest that the increase in spine length with altitude was the result of selection favouring longer spines at higher-altitude sites and/or shorter spines at lower-altitude sites. The altitudinal variation in selection pressure on spine length could reflect changes in local pollinator assemblages with altitude.
MeSH term(s)	Bees ; Animals ; Insecta ; Pollen ; Altitude ; Pollination ; Flowers/anatomy & histology ; Plants ; Caprifoliaceae
Language	English
Publishing date	2022-12-10
Publishing country	England
Document type	Journal Article
ZDB-ID	1464075-2
ISSN	1438-8677 ; 1435-8603
ISSN (online)	1438-8677
ISSN	1435-8603
DOI	10.1111/plb.13493
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Article ; Online: Effects of floral display size, local open raceme density, patch size, and distance between patches on pollinator behaviour in Salvia nipponica.

Murakoshi, Noriko / Itagaki, Tomoyuki / Oguro, Michio / Sakai, Satoki

Scientific reports

2024 Volume 14, Issue 1, Page(s) 967

Abstract: Flowers cluster at various spatial scales, so pollinators use information from multiple scales when foraging in natural plant populations. Little is known about the effects of interactions between scales or their relative strength. We examined bumblebee ... ...

Abstract	Flowers cluster at various spatial scales, so pollinators use information from multiple scales when foraging in natural plant populations. Little is known about the effects of interactions between scales or their relative strength. We examined bumblebee foraging behaviour in a natural population of Salvia nipponica in 10 and 7 patches in 2019 and 2020, respectively. We recorded within-patch factors (display size of racemes and local open raceme densities) and patch-level factors (patch size and distance from the nearest patch) and analysed their relationships with pollinator behaviour. The numbers of visits per raceme and flower were mainly affected by the interaction of patch size and raceme density; they were higher in locations with lower raceme density in larger patches. The ratio of flowers visited to all open flowers in a raceme during a raceme visit, which relates to a bumblebee's choice to leave a raceme, was mainly affected by the interaction of display size and local open raceme density; in 2019 it was higher in racemes with smaller display sizes, while in 2020 the strength and direction of the relationship depended on the open raceme density. These results suggest that pollinators relied on the sizes of flower clusters at different spatial scales when visiting and leaving racemes and adjusted their responses to the sizes of flower clusters depending on the distances between clusters. Therefore, it is important to evaluate factors at various spatial scales and their interactions to fully understand pollinator behaviour in natural plant populations.
MeSH term(s)	Salvia ; Flowers ; Records
Language	English
Publishing date	2024-01-10
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-51327-w
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Article ; Online: Cannulation of pancreaticojejunostomy anastomosis with a novel controllable catheter.

Kuraoka, Naosuke / Ujihara, Tetsuro / Sakai, Shun

Journal of hepato-biliary-pancreatic sciences

2024

Language	English
Publishing date	2024-01-06
Publishing country	Japan
Document type	Case Reports
ZDB-ID	2536236-7
ISSN	1868-6982 ; 1868-6974
ISSN (online)	1868-6982
ISSN	1868-6974
DOI	10.1002/jhbp.1410
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