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Article ; Online: Application of CRISPR-Cas9 genome editing technology in various fields: A review.

Ansori, Arif Nm / Antonius, Yulanda / Susilo, Raden Jk / Hayaza, Suhailah / Kharisma, Viol D / Parikesit, Arli A / Zainul, Rahadian / Jakhmola, Vikash / Saklani, Taru / Rebezov, Maksim / Ullah, Md Emdad / Maksimiuk, Nikolai / Derkho, Marina / Burkov, Pavel

Narra J

2023  Volume 3, Issue 2, Page(s) e184

Abstract: CRISPR-Cas9 has emerged as a revolutionary tool that enables precise and efficient modifications of the genetic material. This review provides a comprehensive overview of CRISPR-Cas9 technology and its applications in genome editing. We begin by ... ...

Abstract CRISPR-Cas9 has emerged as a revolutionary tool that enables precise and efficient modifications of the genetic material. This review provides a comprehensive overview of CRISPR-Cas9 technology and its applications in genome editing. We begin by describing the fundamental principles of CRISPR-Cas9 technology, explaining how the system utilizes a single guide RNA (sgRNA) to direct the Cas9 nuclease to specific DNA sequences in the genome, resulting in targeted double-stranded breaks. In this review, we provide in-depth explorations of CRISPR-Cas9 technology and its applications in agriculture, medicine, environmental sciences, fisheries, nanotechnology, bioinformatics, and biotechnology. We also highlight its potential, ongoing research, and the ethical considerations and controversies surrounding its use. This review might contribute to the understanding of CRISPR-Cas9 technology and its implications in various fields, paving the way for future developments and responsible applications of this transformative technology.
Language English
Publishing date 2023-08-27
Publishing country Indonesia
Document type Journal Article ; Review
ISSN 2807-2618
ISSN (online) 2807-2618
DOI 10.52225/narra.v3i2.184
Database MEDical Literature Analysis and Retrieval System OnLINE

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