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Article: Geoengineering characteristics modeling of Eocene limestone beds of the upper plateau of Mokattam area, Egypt using GIS techniques

Elgohary, Ahmed / Saad, Ahmed M. / Sakr, Mohamed A. H. / Omar, Ali E.

Environmental earth sciences. 2022 Feb., v. 81, no. 3

2022

Abstract: This research paper is concerned with studying and evaluating the geoengineering characteristics and potential risks of the area under study with a view to safe urban expansion using GIS techniques. Different geotechnical laboratory tests such Atterberg ... ...

Abstract	This research paper is concerned with studying and evaluating the geoengineering characteristics and potential risks of the area under study with a view to safe urban expansion using GIS techniques. Different geotechnical laboratory tests such Atterberg limits, free swelling test, swell potential and pressure tests, chemical analysis, unconfined compressive strength (UCS) and rock quality designation (RQD) were performed on 28 boreholes (95 samples). Furthermore, X-ray diffraction was used to examine clay minerals. The results indicate that the UCS values range from 47 to 72.2 kg/cm² and RQD from 21 to 45%. The free swell ratio ranges from 110 to 120%, and the plasticity index from 34 to 37%. In addition, GIS techniques have been utilized to produce the distribution layers of different geotechnical characteristics, then integrated to produce a geospatial urban model for delineating and defining safe and dangerous urban zones. This model is classified into four classes: low, moderate, high and very high hazard. Low and moderate hazards were detected in the major portion of the survey area. These portions are suitable for foundations at shallow depths. However, high to very high hazards were detected in the southeast portion of the study area. The reason for these areas is caused by the existence of heavily fractured limestone and highly swelling clay layers. This model would aid in the creation and discovery of the best areas of shallow base in the region under consideration.
Keywords	Eocene epoch ; X-ray diffraction ; chemical analysis ; clay ; compression strength ; environmental engineering ; limestone ; models ; plasticity ; surveys ; urbanization ; Egypt
Language	English
Dates of publication	2022-02
Size	p. 81.
Publishing place	Springer Berlin Heidelberg
Document type	Article
ZDB-ID	2493699-6
ISSN	1866-6299 ; 1866-6280
ISSN (online)	1866-6299
ISSN	1866-6280
DOI	10.1007/s12665-022-10178-2
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Antitumor and Antibacterial Activity of Ni(II), Cu(II), Ag(I), and Hg(II) Complexes with Ligand Derived from Thiosemicarbazones: Characterization and Theoretical Studies.

Alshater, Heba / Al-Sulami, Ahlam I / Aly, Samar A / Abdalla, Ehab M / Sakr, Mohamed A / Hassan, Safaa S

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 6

Abstract: Four new complexes ( ... ...

Abstract	Four new complexes (Ni
MeSH term(s)	Molecular Docking Simulation ; Ligands ; Thiosemicarbazones/pharmacology ; Thiosemicarbazones/chemistry ; Nickel/pharmacology ; Nickel/chemistry ; Coordination Complexes/chemistry ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Chelating Agents ; Mercury/pharmacology ; Copper/pharmacology ; Copper/chemistry
Chemical Substances	Ligands ; Thiosemicarbazones ; Nickel (7OV03QG267) ; Coordination Complexes ; Anti-Bacterial Agents ; Chelating Agents ; Mercury (FXS1BY2PGL) ; Copper (789U1901C5)
Language	English
Publishing date	2023-03-13
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28062590
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Article ; Online: Geotechnical and environmental radioactivity investigations at Al Sādis Min Uktōber city, Cairo municipality (Egypt), for the high-speed railway construction.

Omar, Ali E / Sakr, Mohamed A H / Taalab, Sherif A / Bakhit, Abu-Bakr A / Pugliese, M / La Verde, G / Hanfi, Mohamed Y

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

2023 Volume 193, Page(s) 110664

Abstract: The present study aims to evaluate the possibility of constructing a new high-speed railway (HSR) at Al Sādis Min Uktōber city, Cairo (Egypt): geotechnical and environmental radiological hazards are estimated from several collected soil and water samples. ...

Abstract	The present study aims to evaluate the possibility of constructing a new high-speed railway (HSR) at Al Sādis Min Uktōber city, Cairo (Egypt): geotechnical and environmental radiological hazards are estimated from several collected soil and water samples. A variety of laboratory geotechnical tests such as grain size, free swelling test, liquid and plastic limits, chemical analysis and uniaxial compression strength are applied to sixty-one drill holes. A geotechnical examination of the coarse-grained soil at the foundation level classified it as poorly graded soil. The results of the investigation of fine-grained soil at the foundation level shown that the liquid limit ranges from 22% to 55%, the plastic limit ranges from 12% to 28%, the plasticity index varies from 11% to 33%, free swelling varies from 51% to 71%. Mechanically, the uniaxial compressive strength values on rock samples range from 6.96 MPa to 142.39 MPa. The radioactive study is performed to detect the
Language	English
Publishing date	2023-01-13
Publishing country	England
Document type	Journal Article
ZDB-ID	1142596-9
ISSN	1872-9800 ; 0883-2889 ; 0969-8043
ISSN (online)	1872-9800
ISSN	0883-2889 ; 0969-8043
DOI	10.1016/j.apradiso.2023.110664
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Article ; Online: Assessment of radioactivity and geotechnical characteristics of soil foundation for suitability of safe urban extension using geospatial technology new Sahl Hasheesh Marin Port, eastern desert, Egypt [Correction: Dec. 2022, 103(6), p. 1468]

Saad, Ahmed M. / Sakr, Mohamed A. H. / Omar, Ali E. / Mohamed, Ahmed W. / Temsah, Yasser A.

International Journal of Environmental Analytical Chemistry. 2022 Dec. 23, v. 102, no. 17, p. 5715-5737

2022 , Page(s) 5715–5737

Abstract: In this study an appropriate investigation was carried out to assess the geotechnical parameters and possible health risks to verify the suitability of Sahl Hasheesh (SH) area for the urban extension using GIS techniques. For this purpose, eighty-three ... ...

Abstract	In this study an appropriate investigation was carried out to assess the geotechnical parameters and possible health risks to verify the suitability of Sahl Hasheesh (SH) area for the urban extension using GIS techniques. For this purpose, eighty-three bore holes were drilled at depths 20 m below the ground surface. Laboratory tests were performed on representative soil and rock samples to determine their physical, mechanical and chemical characteristics such as: grain size distribution, chemical analysis, Atterberg limits and point load strength. Also, airborne gamma-ray spectrometry was used for finding the three-radioactive elements (K, U and Th) concentrations near the ground surface of the study area. These concentrations were analysed for specific activity concentrations of ²³⁸U, ²³²Th and ⁴⁰K radionuclide’s to calculate the exposure dose rate (DR) and annual effective dose rate (AEDR). The annual effective dose rate ranges from 0.2 mSv/y to 4 mSv/y under permissible level, so the study area is radioactively safe. GIS techniques were used to produce many geospatial layers of radioactive and geotechnical properties and integrated all these layers to build the geospatial urban extension model. The urban extension model illustrated that the ideal and good zones were observed in most of the study area. But, the marginal to poor zones were observed in the northwest and central regions of the study area. This model will be useful in the management and development of the area under study. In addition, it will represent a database in the future to decrease the hazards impacts on the construction.
Keywords	chemical analysis ; databases ; geospatial technology ; models ; particle size distribution ; radioactivity ; soil ; spectroscopy ; Egypt ; Geotechnical properties ; gamma ray spectrometry ; radioactive hazard ; GIS ; modelling process
Language	English
Dates of publication	2022-1223
Size	p. 5715-5737
Publishing place	Taylor & Francis
Document type	Article ; Online
ZDB-ID	120480-4
ISSN	1029-0397 ; 0306-7319 ; 0092-9085
ISSN (online)	1029-0397
ISSN	0306-7319 ; 0092-9085
DOI	10.1080/03067319.2020.1802444
Database	NAL-Catalogue (AGRICOLA)

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Article: Geotechnical parameters modelling and the radiation safety of expansive clayey soil treated with waste marble powder: a case study at west Gulf of Suez, Egypt

Sakr, Mohamed A. H / Omar, Ali E / Saad, Ahmed M / Moayedi, Hossein

Environmental earth sciences. 2021 Apr., v. 80, no. 7

2021

Abstract: The present paper aims to reduce and detect the environmental impact of radioelement concentrations and waste marble powder (WMP) in the surrounding environment and additionally, improve the characteristics of the expansive soil and investigate the ... ...

Abstract	The present paper aims to reduce and detect the environmental impact of radioelement concentrations and waste marble powder (WMP) in the surrounding environment and additionally, improve the characteristics of the expansive soil and investigate the effect of stabilizers on the swelling soil to use a foundation layer. Different geotechnical laboratory tests have been performed on representative clay samples to define the physical and mechanical characteristics. The results indicate that the swelling pressure and swelling potential are reduced from (805.7 to 576 kN/m²) and (15.78 to 7.11%), respectively. The plasticity index decreased from 35.9% (high plasticity) to 19.4% (low plasticity), and the free swell index becomes zero by adding waste marble powder. Geospatial techniques have also been used to produce the distributions layers of different geotechnical characteristics and radioelements’ concentrations. These layers were integrated to produce a geospatial model. This model showed a noticeable improvement in the properties of clayey soils after the use of waste marble powder, which ranged from low expansion to high expansion. The radioelement concentrations of all samples are below an acceptable limit, except that the concentration of ⁴⁰K is greater than the acceptable limit. This study recommends a 40% replacement of WMP. This amount is suitable and economical for this kind of treatment because of its positive solutions to protect the environment from pollution and reduce the cost of construction.
Keywords	case studies ; clay ; clay soils ; environmental impact ; models ; plasticity ; pollution ; radiation safety ; Egypt
Language	English
Dates of publication	2021-04
Size	p. 263.
Publishing place	Springer Berlin Heidelberg
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	2493699-6
ISSN	1866-6299 ; 1866-6280
ISSN (online)	1866-6299
ISSN	1866-6280
DOI	10.1007/s12665-021-09573-y
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Article ; Online: The involvement of cytokine gene polymorphism in determining the vulnerability to Blastocystis and Helicobacter pylori co-infection in the Egyptian population.

Ibrahim, Asmaa / Kamel, Nancy O / Rageh, Fatma / Elgamal, Rasha / Mansour Salama, Bassam / Sakr, Mohamed A / Elhoseeny, Mohamed Mahmoud / Osman, Eman M / Sayed, Samar / Ramadan, Manar Ezzelarab

Acta tropica

2024 Volume 252, Page(s) 107137

Abstract: Aims: The present study aimed to identify any potential association between IL-1β and TNF-α gene polymorphism and the risk of Blastocystis infection as well as co-infection of Blastocystis with Helicobacter pylori (H.pylori).: Methodology: A total of ...

Abstract	Aims: The present study aimed to identify any potential association between IL-1β and TNF-α gene polymorphism and the risk of Blastocystis infection as well as co-infection of Blastocystis with Helicobacter pylori (H.pylori). Methodology: A total of 314 stool samples were collected and examined microscopically for the detection of parasitic infection. DNA was extracted from all samples and utilized to identify Blastocystis molecularly. Positive samples were used for H. pylori detection by rapid tests and PCR. Moreover, we investigate polymorphism in the TNF-α gene at position -1031T/C, -308 G/A, and IL-1β at position +3954C/T using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay. Results: Out of the 314 stool samples, Blastocystis was detected in 93 (29.6 %); among them, 54 (58.1 %) had a mixed infection of Blastocystis with H. pylori. The TT genotype of the IL-1β gene at position +3954 was significantly higher in Blasocystis-infected patients than in uninfected patients (17.2% vs. 6.3 %, P = 0.02), which might be considered a risk factor (OR = 3.2; CI =1.21-8.52). The TNF-α at position -1031 TT genotype was significantly higher in Blastocystis-infected patients than uninfected patients (44.1% vs. 10.8 %, P< 0.0001). The T allele (OR= 2.67; CI=1.51-4.72, P = 0.0008) might be considered a risk factor. The TNF- α at position -308 AA genotype is higher in Blasocystis infected than uninfected (17.2% vs 7.2 %, P = 0.03). TNF-α -308 AA (OR = 2.72; CI = 1.08-6.89) and A allele (OR= 1.46; CI= 0.797-2.66) might be considered risk factors. The TNF- α at position -308 G/A showed that the GG is the most frequent genotype in Blastocystis with H. pylori-positive patients with a significant association (P = 0.004), as well as the G allele (P = 0.02). The G allele (OR=1.924; CI= 1.071-3.454) might be considered a risk factor for co-infection of Blastocystis and H. pylori. Conclusion: SNPs (-1031 T/C and -308 G/A) of the TNF-α and (+3954 C/T) of the IL-1β may be a useful marker in the assessment of the risk of Blastocystis infection, and TNF-α at position -308 G/A) may be a predictor for co-infection of Blastocystis with H. pylori.
MeSH term(s)	Humans ; Cytokines/genetics ; Helicobacter pylori/genetics ; Tumor Necrosis Factor-alpha/genetics ; Blastocystis/genetics ; Blastocystis Infections/epidemiology ; Coinfection ; Egypt ; Genetic Predisposition to Disease ; Genotype ; Polymorphism, Single Nucleotide ; Interleukin-1beta/genetics
Chemical Substances	Cytokines ; Tumor Necrosis Factor-alpha ; Interleukin-1beta
Language	English
Publishing date	2024-02-15
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	210415-5
ISSN	1873-6254 ; 0001-706X
ISSN (online)	1873-6254
ISSN	0001-706X
DOI	10.1016/j.actatropica.2024.107137
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Book ; Conference proceedings: Special topics in earthquake geotechnical engineering

Sakr, Mohamed A

(Geotechnical, geological, and earthquake engineering ; 16)

2012

Event/congress	International Conference on Soil Mechanics and Geotechnical Engineering (2009.10.02-03, Alexandria) ; Satellite Conference on Earthquake Geotechnical Engineering (2009.10.02-03, Alexandria)
Author's details	[ed.] by Mohamed A. Sakr
Series title	Geotechnical, geological, and earthquake engineering ; 16
Keywords	Earthquake engineering ; Engineering geology ; Seismology ; Soil dynamics
Language	English
Publisher	Springer
Publishing place	Dordrecht u.a.
Document type	Book ; Conference proceedings
ISBN	9789400720596 ; 9789400720602 ; 9400720599 ; 9400720602
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article: Adipokine (adiponectin-rs1501299) Gene Variant and Patient Characteristics in Relation to Metabolic-associated Fatty Liver Disease.

Mohamed, Amal A / Hassanin, Soha / Mohamed, Ahmed A / Zaafar, Dalia / Mohamed, Rasha / Hassan, Mohamed B / Hassanin, Al-Shaymaa A / Alsayed Abouahmad, Eman / Sakr, Mohamed A / Abd El Salam, Soha M / Abdelghafour, Reem A M / Muharram, Nashwa M / Darwish, Marwa K / Faried, Saadia / Nasraldin, Karmia / Hafez, Wael

Journal of clinical and experimental hepatology

2024 Volume 14, Issue 5, Page(s) 101409

Abstract: Background: Several genetic and metabolic variables, most notably the variation in the adipokine gene rs1501298, have been linked to metabolic-associated fatty liver disease etiopathogenesis (MAFLD). Liver biopsy, the gold standard for diagnosing MAFLD, ...

Abstract	Background: Several genetic and metabolic variables, most notably the variation in the adipokine gene rs1501298, have been linked to metabolic-associated fatty liver disease etiopathogenesis (MAFLD). Liver biopsy, the gold standard for diagnosing MAFLD, is an invasive procedure; therefore, alternative diagnostic methods are required. Consequently, the integration of these metabolic variables with some of the patients' characteristics may facilitate the development of noninvasive diagnostic methods that aid in the early detection of MAFLD, identification of at-risk individuals and planning of management strategies. Methods: This study included 224 Egyptians (107 healthy individuals and 117 MAFLD patients). Age, sex, BMI, clinical and laboratory characteristics, and rs1501299 adipokine gene polymorphisms were examined. The rs1501299 variant, insulin resistance, hypertension, obesity, blood pressure, lipid profile, hemoglobin A1C level, and hepatic fibrosis predictors were evaluated for MAFLD risk. The feasibility and effectiveness of developing non-invasive MAFLD diagnostic models will be investigated. Results: The +276G/T (rs1501299) polymorphism (GG vs GT/TT) was linked with MAFLD (OR: 0.43, CI: 0.26-0.69, Conclusion: The Adipokine variant rs1501299 increased the risk of MAFLD. Identifying and genotyping this variation and other metabolic variables allow for a noninvasive diagnostic model for early MAFLD diagnosis and identification of those at risk. This study illuminates the prevention and management of MAFLD. Further research with more participants is needed to verify these models and to prove their MAFLD diagnostic efficacy.
Language	English
Publishing date	2024-04-08
Publishing country	India
Document type	Journal Article
ISSN	0973-6883
ISSN	0973-6883
DOI	10.1016/j.jceh.2024.101409
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Article ; Online: Egypt's second wave of coronavirus disease of 2019 pandemic and its impact on patients with inflammatory bowel disease.

Askar, Safaa R / Sakr, Mohamed A / Alaty, Waleed H A / Sherief, Ahmed F / Rashad, Heba / Eltabbakh, Mohamed

JGH open : an open access journal of gastroenterology and hepatology

2021 Volume 5, Issue 6, Page(s) 664–668

Abstract: Background and aim: After a decrease of COVID-19 cases in summer, Europe faced the appearance of a COVID-19 second wave. IBD patients are more vulnerable to various emotional and psychological stresses than normal individuals. The aim of this study ... ...

Abstract	Background and aim: After a decrease of COVID-19 cases in summer, Europe faced the appearance of a COVID-19 second wave. IBD patients are more vulnerable to various emotional and psychological stresses than normal individuals. The aim of this study explored the emotional state, perception, and coping strategies of patients with IBD during the COVID 19 pandemic period. Methods: A cross-sectional study was conducted between 15 November and 15 December 2020. Patients presented to IBD Study Group Clinic, Department of Tropical Medicine, Ain Shams University Hospitals. The study included 105 IBD patients. A predesigned questionnaire was used that focused on patients' knowledge of the COVID-19 pandemic, and how it influenced patient care. Patient demographics, disease characteristics, and medication type were analyzed. Results: We found 10.5% of patients stopped or delayed their medications owing to the COVID-19 pandemic second wave and 61% reported that their clinic visits were affected. Seven patients were tested, and two patients reported having been diagnosed with COVID-19, and 18 patients reported having relatives diagnosed with COVID-19. Conclusion: A considerable number of patients with IBD had an interruption to their care because of the second wave COVID-19 pandemic. So, patients with IBD should take attention before, during, and after such pandemics to avoid undesirable disease-related outcomes.
Language	English
Publishing date	2021-05-06
Publishing country	Australia
Document type	Journal Article
ISSN	2397-9070
ISSN (online)	2397-9070
DOI	10.1002/jgh3.12551
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Article ; Online: The Potential Role of Circulating Long Miscellaneous RNAs in the Diagnosis and Prognosis of Hepatitis C Related Hepatocellular Carcinoma.

Abdelsattar, Shimaa / Fahim, Sally A / Kamel, Hala F M / Al-Amodi, Hiba / Kasemy, Zeinab A / Khalil, Fatma O / Abdallah, Mahmoud S / Bedair, Hanan M / Gadallah, Abdel-Naser Abdel-Atty / Sabry, Aliaa / Sakr, Mohamed A / Selim, Mahmoud / Gayed, Eman M Abd El

Non-coding RNA

2023 Volume 9, Issue 5

Abstract: Ribonucleic acids (RNAs) are important regulators of gene expression and crucial for the progression of hepatocellular carcinoma (HCC). This study was designed to determine the diagnostic and prognostic utility of the circulating long miscellaneous RNAs; ...

Abstract	Ribonucleic acids (RNAs) are important regulators of gene expression and crucial for the progression of hepatocellular carcinoma (HCC). This study was designed to determine the diagnostic and prognostic utility of the circulating long miscellaneous RNAs; LINC01419, AK021443, and AF070632 in HCV-related HCC patients. Real-time PCR was used to measure their relative expression levels in the plasma of 194 HCV patients, 120 HCV-related HCC patients and 120 healthy controls. LINC01419 and AK021443 expression levels had significantly increasing linear trend estimates while AF070632 was dramatically downregulated in HCC compared to HCV. Interestingly, LINC01419 and AK021443 served as more significant diagnostic biomarkers for HCC than AF070632 and AFP. Multivariate analysis with cox regression revealed that the high expression of AK021443 [HR = 10.06, CI95%: 3.36-30.07], the high expression of LINC01419 [HR 4.13, CI95%: 1.32-12.86], and the low expression of AF070632 [HR = 2.70, CI95%: 1.07-6.81] were significant potential prognostic factors for HCC. Besides, the Kaplan-Meier analysis showed that HCC patients with high LIN01419 and AK021443 and low AF070632 expression levels had shorter OS. The circulating LINC01419 and AK021443 can be used as noninvasive potential biomarkers for diagnosis and prognosis of HCV-related HCC patients than AF070632 providing new targets for limiting the progression of the disease.
Language	English
Publishing date	2023-10-11
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2813993-8
ISSN	2311-553X ; 2311-553X
ISSN (online)	2311-553X
ISSN	2311-553X
DOI	10.3390/ncrna9050062
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