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Article ; Online: Substituting Low-Calorie Sweetened Beverages for Sugar-Sweetened Beverages to Prevent Obesity and Cardiometabolic Diseases: Still a Good Idea?

Chatelan, Angeline / Raeisi-Dehkordi, Hamidreza / Salehi-Abargouei, Amin

Current developments in nutrition

2024 Volume 8, Issue 3, Page(s) 102105

Abstract: Low-calorie sweeteners (LCSs) and LCS-containing beverages have been proposed as appropriate substitutes for caloric sugars in recent years. In this Perspective, we highlight the recent findings from observational and interventional studies, focusing on ... ...

Abstract	Low-calorie sweeteners (LCSs) and LCS-containing beverages have been proposed as appropriate substitutes for caloric sugars in recent years. In this Perspective, we highlight the recent findings from observational and interventional studies, focusing on obesity, gut microbiome, and cardiometabolic health. We provide public health actors and health care professionals with an insightful overview of recent evidence to bridge the gap between research and practice.
Language	English
Publishing date	2024-02-13
Publishing country	United States
Document type	Journal Article
ISSN	2475-2991
ISSN (online)	2475-2991
DOI	10.1016/j.cdnut.2024.102105
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Article ; Online: Comment on 'Effects of pistachios on anthropometric indices, inflammatory markers, endothelial function and blood pressure in adults: a systematic review and meta-analysis of randomised controlled trials'.

Beigrezaei, Sara / Salehi-Abargouei, Amin

The British journal of nutrition

2021 , Page(s) 1–2

Language	English
Publishing date	2021-09-24
Publishing country	England
Document type	Journal Article
ZDB-ID	280396-3
ISSN	1475-2662 ; 0007-1145
ISSN (online)	1475-2662
ISSN	0007-1145
DOI	10.1017/S0007114521003846
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Article: Dairy intake in association with asthma symptoms among a large sample of children and adolescents: a cross-sectional study.

Jamalvandi, Mona / Sasanfar, Bahareh / Nafei, Zahra / Behniafard, Nasrin / Jafari, Marjan / Salehi-Abargouei, Amin

Frontiers in nutrition

2024 Volume 11, Page(s) 1298704

Abstract: Background and objective: Dairy products may be associated with an increased risk of asthma, although there is little scientific evidence to support this association. The goal of this study was to explore the association between dairy consumption and ... ...

Abstract	Background and objective: Dairy products may be associated with an increased risk of asthma, although there is little scientific evidence to support this association. The goal of this study was to explore the association between dairy consumption and asthma symptoms. Materials and methods: This cross-sectional study was conducted on children and adolescents aged 6-8 and 13-14 years living in central Iran. Dietary food consumption was assessed using a multiple-choice questionnaire. Logistic regression was used to obtain odds ratios for the association between milk, other dairy products, and total dairy consumption with the risk of asthma symptoms. Results: In total, 7,667 participants (3,414 boys and 4,253 girls) were included in the current study. Milk intake and total dairy consumption were not associated with the likelihood of wheezing, asthma confirmed by a doctor, current asthma, and asthma medication use. In addition, there was no association between other dairy product intake and the odds of wheezing in the past 12 months in the crude model. However, after adjusting for several confounders, those in the top category had lower odds of wheezing in the past 12 months than those in the bottom category (OR: 0.58; 95% CI: 0.40-0.85). Conclusion: The consumption of dairy products other than milk, including cheese and yogurt, might reduce the likelihood of wheezing in children and adolescents.
Language	English
Publishing date	2024-03-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2776676-7
ISSN	2296-861X
ISSN	2296-861X
DOI	10.3389/fnut.2024.1298704
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Article: The effect of green tea (

Yazdanpanah, Zeinab / Salehi-Abargouei, Amin / Mozaffari, Zohre / Hemayati, Roya

Frontiers in nutrition

2023 Volume 10, Page(s) 1253275

Abstract: Introduction: Diabetic nephropathy is one of the most important microvascular complications of diabetes. Despite the modern treatments, herbs or medicinal plants have gained wide attention. One of these herbs is green tea (: Methods: Sixty-six ... ...

Abstract	Introduction: Diabetic nephropathy is one of the most important microvascular complications of diabetes. Despite the modern treatments, herbs or medicinal plants have gained wide attention. One of these herbs is green tea ( Methods: Sixty-six individuals with T2DM nephropathy (aged 30-70 years) were randomly assigned to receive three cups of green tea/day ( Results: In total, 64 participants completed the study. Consuming three cups of infusion green tea per day (7.5 gr) led to a significant reduction in serum levels of total cholesterol ( Conclusion: In general, it was found that drinking three cups of green tea infusion (7.5 gr) per day produced beneficial effects on some lipid profiles and HbA1c without any adverse effects on renal function in patients with T2DM nephropathy. More studies are needed to fully elucidate these findings. Clinical trial registration: Iranian Registry of Clinical Trials (www.irct.ir) under registry number: IRCT2014020114538N2.
Language	English
Publishing date	2023-12-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2776676-7
ISSN	2296-861X
ISSN	2296-861X
DOI	10.3389/fnut.2023.1253275
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Article ; Online: The effect of whole egg consumption on weight and body composition in adults: a systematic review and meta-analysis of clinical trials.

Emrani, Arezoo Sadat / Beigrezaei, Sara / Zademohammadi, Faezeh / Salehi-Abargouei, Amin

Systematic reviews

2023 Volume 12, Issue 1, Page(s) 125

Abstract: Background: A limited number of studies have directly examined the effect of whole eggs on body weight and composition in adults, and they have led to inconsistent results. This study aimed to summarize the evidence on the effect of whole egg ... ...

Abstract	Background: A limited number of studies have directly examined the effect of whole eggs on body weight and composition in adults, and they have led to inconsistent results. This study aimed to summarize the evidence on the effect of whole egg consumption on body weight and body composition in adults from clinical trials. Methods: Online databases were searched from inception to April 2023 for clinical trials that directly or indirectly assessed the effect of whole eggs consumption on anthropometric measures including body weight, body mass index (BMI), waist circumference (WC), and fat-free mass (FFM) in adults. A random effects model was used for meta-analysis. Results: In total, 32 controlled clinical trials were included in the systematic review. The analyses revealed that whole egg consumption has no significant effect on body weight (n = 22), BMI (n = 13), WC (n = 10), and FFM (n = 4, P > 0.05). The subgroup analyses showed that whole egg consumption has an increasing effect on body weight and BMI in studies that lasted more than 12 weeks and in unhealthy participants (P < 0.05). A significant increasing effect on BMI was found in studies that the control group did not receive any egg (P < 0.05). Moreover, in studies that there was no significant difference in energy intake between the intervention and control groups, weight, and WC were significantly increased (P < 0.05). Additionally, in studies that participants in the control group received another food or supplement, studies with calorie restriction, and studies on healthy subjects, whole egg intake significantly decreased BMI (P < 0.05). Conclusions: Although whole egg consumption had no adverse effect on body composition and body weight, in overall, it might increase body weight in long term. Egg consumption beneficially affects BMI in healthy people and during weight loss diet. Systematic review registration: This systematic review and meta-analysis is registered in the International Prospective Register of Systematic Reviews (PROSPERO, Registration number: CRD42022308045).
MeSH term(s)	Humans ; Adult ; Body Weight ; Body Mass Index ; Body Composition ; Energy Intake ; Dietary Supplements ; Waist Circumference
Language	English
Publishing date	2023-07-17
Publishing country	England
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2662257-9
ISSN	2046-4053 ; 2046-4053
ISSN (online)	2046-4053
ISSN	2046-4053
DOI	10.1186/s13643-023-02277-3
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Article ; Online: Dietary trans fatty acids and risk of colorectal cancer: a systematic review and meta-analysis of observational studies

Salemi, Fateme / Beigrezaei, Sara / Arabi, Vahid / Taghipour Zahir, Shokouh / Salehi-Abargouei, Amin

Eur J Nutr. 2023 Mar., v. 62, no. 2 p.563-572

2023

Abstract: PURPOSE: Although trans fatty acid has been associated with diabetes and cardiovascular disorders, studies gave conflicting results when examined their impact on colorectal cancer (CRC). The present systematic review and meta-analysis aimed to summarize ... ...

Abstract	PURPOSE: Although trans fatty acid has been associated with diabetes and cardiovascular disorders, studies gave conflicting results when examined their impact on colorectal cancer (CRC). The present systematic review and meta-analysis aimed to summarize the current evidence regarding the association between dietary and tissue trans fatty acids and the risk of CRC. METHODS: We searched PubMed/MEDLINE, EMBASE, Scopus, Web of Science (ISI), and Google Scholar without date and language limitation up to May 2022 and included the eligible studies. The quality of included studies was assessed using the Newcastle–Ottawa scale. The overall odds ratios (ORs) were derived using a random-effects model. RESULTS: In assessment of dietary trans fatty acids 18 studies, including eight cohort, 10 case–control, and observational data from one randomized control trial were included. Although Dietary trans fats were associated with higher risk of CRC (OR = 1.093, 95% CI 1.017, 1.176, P = 0.016; I² = 61.3%), Subgroup analysis by study design yielded an insignificant effect for case–control (OR = 1.152, 95% CI 1.000, 1.328, P = 0.050; I² = 77.2%) and cohort (OR = 1.027, 95% CI 0.976, 1.081, P = 0.299; I² = 0%) studies. Although there was no significant association of trans fatty acids with rectal cancer (OR = 1.093, 95% CI 0.984 to 1.215, P = 0.098; I² = 0%), there was for colon cancer (OR = 1.91, 95% CI 1.062 to 1.335, P = 0.003; I² = 37.6%).The analysis of four studies that evaluated the relation between tissue trans fat and CRC revealed meaningful result (OR = 0.745, 95% CI 0.619, 0.896, P = 0.002; I² = 42.6%). While subgroup assessments for colon cancer (OR = 0.804, 95% CI 0.583, 1.109, P = 0.183; I² = 0%) and plasma trans fatty acids OR = 0.853, 95% CI 0.633, 1.150, P = 0.298; I² = 0%) were insignificant. CONCLUSION: Dietary trans fatty acids increased the risk of CRC, whereas tissue trans fatty acids had a protective effect on CRC. Nonetheless, neither type of trans fatty acid increased the risk of colon or rectal cancer; thus, more prospective studies are needed to determine the validity of these associations.
Keywords	colon ; colorectal neoplasms ; diabetes ; experimental design ; meta-analysis ; observational studies ; protective effect ; risk ; statistical models ; systematic review ; trans fatty acids
Language	English
Dates of publication	2023-03
Size	p. 563-572.
Publishing place	Springer Berlin Heidelberg
Document type	Article ; Online
Note	Review
ZDB-ID	1466536-0
ISSN	1436-6215 ; 1436-6207
ISSN (online)	1436-6215
ISSN	1436-6207
DOI	10.1007/s00394-022-03034-3
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Effects of cinnamon supplementation on serum levels of liver enzymes: A systematic review and meta-analysis of randomized controlled clinical trials

Yazdanpanah, Zeinab / Beigrezaei, Sara / Mohseni-Takalloo, Sahar / Salehi-Abargouei, Amin

Journal of Herbal Medicine. 2023 June, v. 39 p.100655-

2023

Abstract: A systematic review and meta-analysis of the effect of cinnamon supplementation on serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and total bilirubin. PubMed, Scopus, Web of Science (ISI), ... ...

Abstract	A systematic review and meta-analysis of the effect of cinnamon supplementation on serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), and total bilirubin. PubMed, Scopus, Web of Science (ISI), Embase, Cochran, and Google Scholar were searched up to December 26, 2021, for relevant randomized controlled clinical trials (RCTs). The random-effects model was used to estimate the overall effects. Eight trials with 10 treatment arms were included in the meta-analysis. The meta-analysis revealed no signiﬁcant effect of cinnamon supplementation on ALT [weighted mean difference (WMD) = −3.74 U/L, 95 % CI: − 8.88, 1.40, P = 0.15], AST (WMD = −2.69 U/L, 95 % CI: −6.23, 0.84, P = 0.13), ALP (WMD = 4.79 U/L, 95 % CI: −0.22, 9.81, P = 0.06) and total bilirubin levels (WMD = 0.04 mg/dL, 95 % CI: −0.08, 0.17, P = 0.49). Subgroup analysis indicated the beneficial effect of > 2000 mg/day of cinnamon extract on serum ALT levels (P < 0.05). Moreover, cinnamon could be effective in reducing AST levels when taken before meals, and the treatment duration was longer than 12 weeks in studies done in T2DM (P < 0.05). Extracts of cinnamon remarkably decreased ALT and AST levels at a dosage of > 2000 mg/day, when consumed before meals in T2DM patients in trials lasting ≥ 12 weeks. Further large-scale high-quality RCTs assessing the efficacy of cinnamon on liver parameters as a primary outcome variable are recommended.
Keywords	alanine transaminase ; alkaline phosphatase ; aspartate transaminase ; bilirubin ; blood serum ; cinnamon ; herbal medicines ; liver ; meta-analysis ; statistical models ; systematic review ; Aspartate aminotransferases
Language	English
Dates of publication	2023-06
Publishing place	Elsevier GmbH
Document type	Article ; Online
Note	Pre-press version
ISSN	2210-8033
DOI	10.1016/j.hermed.2023.100655
Database	NAL-Catalogue (AGRICOLA)

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Article: Efficacy of combination triple therapy with vasopressin, steroid, and epinephrine in cardiac arrest: a systematic review and meta-analysis of randomized-controlled trials.

Saghafi, Fatemeh / Bagheri, Negar / Salehi-Abargouei, Amin / Sahebnasagh, Adeleh

Journal of intensive care

2022 Volume 10, Issue 1, Page(s) 5

Abstract: Background: This study investigated whether combination therapy with vasopressin, steroid, and epinephrine (VSE) improves in-hospital survival and return of spontaneous circulation (ROSC) during and after resuscitation in-hospital cardiac arrest (CA).!## ...

Abstract	Background: This study investigated whether combination therapy with vasopressin, steroid, and epinephrine (VSE) improves in-hospital survival and return of spontaneous circulation (ROSC) during and after resuscitation in-hospital cardiac arrest (CA). Materials and methods: Various databases were explored from inception until October 2021 for relevant published clinical trials and cohort studies. Results: Three clinical trials were included. Pooled analysis suggested that VSE was significantly associated with increased ROSC in patients with in-hospital CA (IHCA) (odds ratio (OR): 2.281, 95% confidence interval (CI): 1.304-3.989, P value = 0.004). Meta-analysis of two studies (368 patients) demonstrated a significant difference in the reduction of mean arterial pressure (MAP) during and 15-20 min after cardiopulmonary resuscitation (standardized mean difference (SMD): 1.069, 95% CI: 0.851-1.288, P value < 0.001), renal failure free days (SMD = 0.590; 95% CI: 0.312-0.869 days; P value < 0.001), and coagulation failure free days (SMD = 0.403; 95% CI: 0.128-0.679, P value = 0.004). However, no significant difference was observed for survival-to-discharge ratio (OR: 2.082, 95% CI: 0.638-6.796, P value = 0.225) and ventilator free days (SMD = 0.201, 95% CI: - 0.677, 1.079 days; P value = 0.838). Conclusions: VSE combination therapy during and after IHCA may have beneficial effects in terms of the ROSC, renal and circulatory failure free days, and MAP. Prospero registration: CRD42020178297 (05/07/2020).
Language	English
Publishing date	2022-02-02
Publishing country	England
Document type	Journal Article
ZDB-ID	2739853-5
ISSN	2052-0492
ISSN	2052-0492
DOI	10.1186/s40560-022-00597-5
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Article ; Online: Therapeutic Role of HAT Therapy in Sepsis: A Systematic Review and Meta-Analysis.

Saghafi, Fatemeh / Boostani Moghadam, Zahra / Salehi-Abargouei, Amin / Beigrezaei, Sara / Sohrevardi, Seyed Mojtaba / Jamialahmadi, Tannaz / Sahebnasagh, Adeleh / Sahebkar, Amirhossein

Current medicinal chemistry

2024

Abstract: Background: This systematic review and meta-analysis aimed to determine whether the combination of hydrocortisone, vitamin C (ascorbic acid), and thiamine (HAT therapy) diminishes the mortality and is effective in expediting the resolution of sepsis and ...

Abstract	Background: This systematic review and meta-analysis aimed to determine whether the combination of hydrocortisone, vitamin C (ascorbic acid), and thiamine (HAT therapy) diminishes the mortality and is effective in expediting the resolution of sepsis and septic shock or not. Methods: The following databases of PubMed, Scopus, ISI Web of Science, and Google Scholar were explored until March 2021 for all existing literature related to this field. An automatic alert for all databases was also activated to update our search. Meta-analysis was performed on clinical trials and cohorts separately as well as on all the pooled populations. Results: This study evaluated nine clinical trials (1358 participants) and nine cohorts (339,437 participants) and is the most comprehensive systematic review in this field. The results of our meta-analysis demonstrated a significant difference in the reduction of Sepsis-Related Organ Failure Assessment (SOFA) score changes (Δ-SOFA) over 72 h (Standard Mean Difference (SMD) = -0.429; 95% CI: -0.737, 0.120; P = 0.006), duration of vasopressor (VP) (SMD = -0.373; 95% CI: -0.619, -0.128; P = 0.003), and procalcitonin (PCT) clearance (SMD = 0.496; 95% CI: 0.061, 0.931%; P = 0.026). Considering the results of cohorts, HAT therapy was effective in the survival of intensive care units (ICUs) patients (OR = 0.641; 95% CI: 0.423-0.970, P = 0.035). However, no significant difference was observed between the intervention and control groups in hospital mortality (Odds Ratio (OR) = 0.811, 95% CI: 0.544-1.209, P = 0.304), 28- to 30-day mortality (OR = 1.000; 95% CI: 0.782-1.279, P = 0.998), new onset acute kidney injury requiring renal replacement therapy ((OR = 0.856, 95% CI: 0.526, 1.391; P = 0.529), in-hospital length of stay (LOS) (SMD = 0.090; 95% CI: -0.036, 0.216 days; P = 0.162), LOS in ICU (SMD = 0.016, 95% CI: -0.138, 0.170 days; P = 0.838), and mechanical ventilation-free days (SMD = 0.004; 95% CI: -0.154, 0.163 days; P = 0.956). Conclusion: Supplementation of septic and septic shock patients with HAT therapy has significant beneficial effects on SOFA score over 72 hours, duration of exogenous vasopressor infusion and procalcitonin clearance. Considering the results of cohort studies, supplementation with HAT is efficacious in reducing ICU mortality.
Language	English
Publishing date	2024-01-22
Publishing country	United Arab Emirates
Document type	Journal Article
ZDB-ID	1319315-6
ISSN	1875-533X ; 0929-8673
ISSN (online)	1875-533X
ISSN	0929-8673
DOI	10.2174/0109298673245464231121094448
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Article ; Online: Association between Adherence to the Mediterranean Diet and Risk of Type 2 Diabetes: An Updated Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.

Sarsangi, Peyman / Salehi-Abargouei, Amin / Ebrahimpour-Koujan, Soraiya / Esmaillzadeh, Ahmad

Advances in nutrition (Bethesda, Md.)

2022 Volume 13, Issue 5, Page(s) 1787–1798

Abstract: Despite earlier meta-analyses on the association between adherence to a Mediterranean diet (MD) and risk of diabetes, there is no comprehensive and updated study assessing this issue. Furthermore, no earlier study has examined the nonlinear dose-response ...

Abstract	Despite earlier meta-analyses on the association between adherence to a Mediterranean diet (MD) and risk of diabetes, there is no comprehensive and updated study assessing this issue. Furthermore, no earlier study has examined the nonlinear dose-response relation between consumption of an MD and risk of diabetes. The current systematic review and meta-analysis was conducted to investigate the linear and nonlinear dose-response relation between MD and incidence of diabetes. Using relevant keywords, electronic searches for prospective studies were conducted in ISI Web of Science, PubMed, and Scopus until January 2022. The reported HRs or ORs in the primary studies were regarded as RRs. The overall effect was calculated using a random-effects model that accounts for between-study variability. The potential nonlinear dose-response associations were tested using a 2-stage hierarchical regression model. Based on 16 prospective studies (with 17 effect sizes), we found that the greatest adherence to the MD was significantly associated with a reduced risk of diabetes (pooled RR: 0.83; 95% CI: 0.77, 0.90; I2 = 79%, P ≤ 0.001). Based on linear dose-response analysis, each 1-score increase in the Mediterranean diet score was associated with a 3% decreased risk of diabetes (HR = 0.97; 95% CI: 0.96, 0.98; P < 0.001). A nonlinear relation (P-nonlinearity = 0.001) was also observed between MD score and risk of type 2 diabetes. Even modest adherence to the MD was linked to a decreased incidence of type 2 diabetes. The protocol is also registered in the International Prospective Register Of Systematic Reviews (PROSPERO) database (https://www.crd.york.ac.uk/PROSPERO/; registration ID: CRD 42021265332).
MeSH term(s)	Diabetes Mellitus, Type 2/epidemiology ; Diabetes Mellitus, Type 2/etiology ; Diabetes Mellitus, Type 2/prevention & control ; Diet, Mediterranean ; Humans ; Incidence ; Prospective Studies
Language	English
Publishing date	2022-04-14
Publishing country	United States
Document type	Journal Article ; Meta-Analysis ; Systematic Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2583634-1
ISSN	2156-5376 ; 2156-5376
ISSN (online)	2156-5376
ISSN	2156-5376
DOI	10.1093/advances/nmac046
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