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  1. Article ; Online: Chemical composition, antifungal, antibiofilm, and molecular docking studies of

    Rahim, Faezatul Alwani Mohd / Salleh, Wan Mohd Nuzul Hakimi Wan / Arzmi, Mohd Hafiz / Salihu, Abubakar Siddiq

    Zeitschrift fur Naturforschung. C, Journal of biosciences

    2024  

    Abstract: The current study describes the chemical composition, antifungal, antibiofilm, antibacterial and molecular docking studies ... ...

    Abstract The current study describes the chemical composition, antifungal, antibiofilm, antibacterial and molecular docking studies of
    Language English
    Publishing date 2024-03-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124636-7
    ISSN 1865-7125 ; 0341-0382 ; 0341-0471 ; 0939-5075
    ISSN (online) 1865-7125
    ISSN 0341-0382 ; 0341-0471 ; 0939-5075
    DOI 10.1515/znc-2023-0133
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 962: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Chemical composition, acetylcholinesterase inhibition and molecular docking studies of essential oil from

    Salihu, Abubakar Siddiq / Salleh, Wan Mohd Nuzul Hakimi Wan / Ogunwa, Tomisin Happy

    Natural product research

    2023  , Page(s) 1–6

    Abstract: ... The ... ...

    Abstract The genus
    Language English
    Publishing date 2023-02-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2023.2184359
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Essential oils composition of

    Salleh, Wan Mohd Nuzul Hakimi Wan / Salihu, Abubakar Siddiq / Ab Ghani, Nurunajah

    Natural product research

    2023  Volume 38, Issue 4, Page(s) 629–633

    Abstract: This study was designed to examine the essential oils compositions ... ...

    Abstract This study was designed to examine the essential oils compositions of
    MeSH term(s) Oils, Volatile/pharmacology ; Oils, Volatile/chemistry ; Litsea/chemistry ; Cholinesterase Inhibitors/pharmacology ; Butyrylcholinesterase ; Acetylcholinesterase ; Gas Chromatography-Mass Spectrometry ; Tetrahydronaphthalenes ; Sesquiterpenes, Eudesmane
    Chemical Substances Oils, Volatile ; beta-selinene (17066-67-0) ; Cholinesterase Inhibitors ; Butyrylcholinesterase (EC 3.1.1.8) ; Acetylcholinesterase (EC 3.1.1.7) ; Tetrahydronaphthalenes ; Sesquiterpenes, Eudesmane
    Language English
    Publishing date 2023-02-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2023.2180507
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Essential oil composition, anti-tyrosinase activity, and molecular docking studies of

    Salihu, Abubakar Siddiq / Salleh, Wan Mohd Nuzul Hakimi Wan / Setzer, William N

    Zeitschrift fur Naturforschung. C, Journal of biosciences

    2023  Volume 78, Issue 7-8, Page(s) 293–298

    Abstract: ... ...

    Abstract Knema
    MeSH term(s) Oils, Volatile/pharmacology ; Oils, Volatile/chemistry ; Molecular Docking Simulation ; Myristicaceae/metabolism ; Gas Chromatography-Mass Spectrometry ; Monophenol Monooxygenase
    Chemical Substances Oils, Volatile ; selinene ; Monophenol Monooxygenase (EC 1.14.18.1)
    Language English
    Publishing date 2023-03-27
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124636-7
    ISSN 1865-7125 ; 0341-0382 ; 0341-0471 ; 0939-5075
    ISSN (online) 1865-7125
    ISSN 0341-0382 ; 0341-0471 ; 0939-5075
    DOI 10.1515/znc-2023-0003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 962: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: A systematic review of botany, phytochemicals and pharmacological properties of "

    Salleh, Wan Mohd Nuzul Hakimi Wan

    Zeitschrift fur Naturforschung. C, Journal of biosciences

    2020  Volume 76, Issue 3-4, Page(s) 93–102

    Abstract: ... Hoja ... ...

    Abstract Hoja santa
    MeSH term(s) Antioxidants/chemistry ; Antioxidants/therapeutic use ; Benzoic Acid/chemistry ; Medicine, Traditional ; Phytochemicals/chemistry ; Phytochemicals/therapeutic use ; Phytotherapy ; Piper/chemistry ; Piper/genetics ; Piper/growth & development ; Plant Extracts/chemistry ; Plant Extracts/therapeutic use
    Chemical Substances Antioxidants ; Phytochemicals ; Plant Extracts ; Benzoic Acid (8SKN0B0MIM)
    Language English
    Publishing date 2020-09-22
    Publishing country Germany
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 124636-7
    ISSN 1865-7125 ; 0341-0382 ; 0341-0471 ; 0939-5075
    ISSN (online) 1865-7125
    ISSN 0341-0382 ; 0341-0471 ; 0939-5075
    DOI 10.1515/znc-2020-0116
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 962: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Chemical Composition, Anti-tyrosinase Activity and Molecular Docking Studies of Knema malayana Warb. Essential Oil

    Salihu, Abubakar Siddiq / Salleh, Wan Mohd Nuzul Hakimi Wan

    Journal of Essential Oil Bearing Plants. 2023 Mar. 04, v. 26, no. 2 p.253-260

    2023  

    Abstract: Essential oils produced from aromatic plants denote significant biological activities and are gaining prominence in scientific research. In this study, the chemical composition, anti-tyrosinase activity, and molecular docking studies of Knema malayana ... ...

    Abstract Essential oils produced from aromatic plants denote significant biological activities and are gaining prominence in scientific research. In this study, the chemical composition, anti-tyrosinase activity, and molecular docking studies of Knema malayana Warb. essential oil was investigated. A hydrodistillation method was used to produce the essential oil, characterised by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC/MS). Additionally, anti-tyrosinase activity was evaluated against mushroom tyrosinase, while molecular docking studies were performed with the major components. A total of 38 components (98.9%) were successfully identified in the essential oil, which was characterised by high proportions of δ-cadinene (20.2%), α-cadinol (13.7%), α-amorphene (10.3%), γ-cadinene (6.3%), α-gurjunene (5.3%), γ-gurjunene (5.3%), and α-muurolene (5.0%). The essential oil demonstrated moderate activity towards tyrosinase activity with an IC₅₀ value of 85.3 μg/mL. Consequently, the best docking energy was observed with α-amorphene (-6.9 Kcal/mol), which successfully formed interactions with His263, Phe264, and Val283. These interactions were essential amino acid residues of the tyrosinase receptor.
    Keywords chemical composition ; energy ; essential amino acids ; essential oils ; gas chromatography-mass spectrometry ; hydrodistillation ; mushrooms ; Essential oil ; Myristicaceae ; Knema malayana ; tyrosinase ; δ-cadinene
    Language English
    Dates of publication 2023-0304
    Size p. 253-260.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ISSN 0976-5026
    DOI 10.1080/0972060X.2023.2191792
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: A systematic review of botany, phytochemicals and pharmacological properties of “Hoja santa” (Piper auritum Kunth)

    Salleh, Wan Mohd Nuzul Hakimi Wan

    Zeitschrift für Naturforschung. 2021 Mar. 26, v. 76, no. 3-4

    2021  

    Abstract: Hoja santa (Piper auritum) refers to an important presence in Mexican cuisine. The information of this review article was gathered from several electronic sources such as Scopus, Medline, Scielo, ScienceDirect, SciFinder, Web of Science, Google Scholar ... ...

    Abstract Hoja santa (Piper auritum) refers to an important presence in Mexican cuisine. The information of this review article was gathered from several electronic sources such as Scopus, Medline, Scielo, ScienceDirect, SciFinder, Web of Science, Google Scholar and Lilacs. Phytochemical studies have revealed the presence of benzoic acid derivatives, phenylpropanoids and triterpenoids, while the essential oils have shown its richness in safrole, hence it has several activities, such as antioxidant, toxicity, insecticidal, anti-diabetic and cytotoxic properties. This review is expected to draw the attention of medical professionals and the general public towards P. auritum as well as to open the door for detailed research in the future.
    Keywords Piper auritum ; antioxidants ; benzoic acid ; cuisine ; cytotoxicity ; phenylpropanoids ; safrole ; systematic review ; triterpenoids
    Language English
    Dates of publication 2021-0326
    Size p. 93-102.
    Publishing place De Gruyter
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 124636-7
    ISSN 1865-7125 ; 0341-0382 ; 0341-0471 ; 0939-5075
    ISSN (online) 1865-7125
    ISSN 0341-0382 ; 0341-0471 ; 0939-5075
    DOI 10.1515/znc-2020-0116
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 4' 47/11 c: Show issues
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  8. Article ; Online: Intermedianin, a new furofuran lignan from the leaves of

    Salihu, Abubakar Siddiq / Salleh, Wan Mohd Nuzul Hakimi Wan / Barker, David / Arzmi, Mohd Hafiz / Ab Ghani, Nurunajah / Rasol, Nurulfazlina Edayah

    Natural product research

    2024  , Page(s) 1–9

    Abstract: Phytochemical investigation of the leaves ... ...

    Abstract Phytochemical investigation of the leaves of
    Language English
    Publishing date 2024-04-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2024.2345758
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Chemical Composition and Anticholinesterase Inhibitory Activity of Essential Oils from Magnolia villosa (Miq.) H.Keng. and Magnolia maingayi King. Leaves

    Salleh, Wan Mohd Nuzul Hakimi Wan / Salihu, Abubakar Siddiq / Yahaya, Ahmad Azrul Hakim / Ghani, Nurunajah Ab

    Journal of Essential Oil Bearing Plants. 2023 Mar. 04, v. 26, no. 2 p.486-492

    2023  

    Abstract: This study aimed to investigate the chemical compositions of the leaf essential oils of Magnolia villosa (Miq.) H. Keng. and M. maingayi King. growing in Malaysia. The leaf essential oils were obtained by hydrodistillation and fully characterized by gas ... ...

    Abstract This study aimed to investigate the chemical compositions of the leaf essential oils of Magnolia villosa (Miq.) H. Keng. and M. maingayi King. growing in Malaysia. The leaf essential oils were obtained by hydrodistillation and fully characterized by gas chromatography and gas chromatography-mass spectrometry. Analysis of M. villosa and M. maingayi leaf essential oils resulted in 96.4% and 98.7% of the total essential oil, respectively. The main components of M. villosa leaf essential oil were β-caryophyllene (32.8%) and α-humulene (8.8%), while in M. maingayi leaf essential oil gave β-elemene (27.4%), β-caryophyllene (16.4%), and (E)-nerolidol (14.4%). Anticholinesterase inhibitory activity was also evaluated using acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory assays. M. villosa leaf essential oil revealed a moderate inhibitory effect on AChE (percentage inhibition, I%: 62.5%) and BChE (I%: 74.8%) at a concentration of 1,000 μg/mL. In conclusion, the leaf essential oils of M. villosa and M. maingayi were characterized and showed promising anticholinesterase inhibitory activity, suggesting their potential as natural sources of therapeutic agents for managing cholinergic dysfunction-related diseases.
    Keywords Magnolia ; acetylcholinesterase ; chemical composition ; cholinesterase ; essential oils ; gas chromatography-mass spectrometry ; hydrodistillation ; leaves ; therapeutics ; Malaysia ; β-caryophyllene ; β-elemene ; essential oil ; Magnolia villosa ; Magnolia maingayi
    Language English
    Dates of publication 2023-0304
    Size p. 486-492.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ISSN 0976-5026
    DOI 10.1080/0972060X.2023.2208160
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Chemical composition and anticholinesterase inhibitory activity of Pavetta graciliflora Wall. ex Ridl. essential oil

    Salleh, Wan Mohd Nuzul Hakimi Wan / Khamis, Shamsul

    Zeitschrift für Naturforschung. 2020 Nov. 26, v. 75, no. 11-12

    2020  

    Abstract: Chemical composition and anticholinesterase activity of the essential oil of Pavetta graciliflora Wall. ex Ridl. (Rubiaceae) was examined for the first time. The essential oil was obtained by hydrodistillation and was fully characterized by gas ... ...

    Abstract Chemical composition and anticholinesterase activity of the essential oil of Pavetta graciliflora Wall. ex Ridl. (Rubiaceae) was examined for the first time. The essential oil was obtained by hydrodistillation and was fully characterized by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of 20 components were identified in the essential oil, which made up 92.85% of the total oil. The essential oil is composed mainly of β-caryophyllene (42.52%), caryophyllene oxide (25.33%), β-pinene (8.67%), and α-pinene (6.52%). The essential oil showed weak inhibitory activity against acetylcholinesterase (AChE) (I%: 62.5%) and butyrylcholinesterase (BChE) (I%: 65.4%) assays. Our findings were shown to be very useful for the characterization, pharmaceutical, and therapeutic applications of the essential oil from P. graciliflora.
    Keywords Rubiaceae ; acetylcholinesterase ; chemical composition ; cholinesterase ; essential oils ; gas chromatography-mass spectrometry ; hydrodistillation ; oils ; therapeutics
    Language English
    Dates of publication 2020-1126
    Size p. 467-471.
    Publishing place De Gruyter
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 124636-7
    ISSN 1865-7125 ; 0341-0382 ; 0341-0471 ; 0939-5075
    ISSN (online) 1865-7125
    ISSN 0341-0382 ; 0341-0471 ; 0939-5075
    DOI 10.1515/znc-2020-0075
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

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