Article ; Online: Use of O RhD-negative red blood cells: A nationwide, prospective audit.
2022 Volume 117, Issue 11, Page(s) 1279–1286
Abstract: Background and objectives: Despite declining transfusion rates, overuse of O RhD-negative red blood cells (RBCs) risks the secure supply of this limited resource. A nationwide prospective audit was performed in Finland to understand the clinical use and ...
| Abstract | Background and objectives: Despite declining transfusion rates, overuse of O RhD-negative red blood cells (RBCs) risks the secure supply of this limited resource. A nationwide prospective audit was performed in Finland to understand the clinical use and inventory management of O RhD-negative units. Our aim was to identify areas where policy changes could help alleviate the shortage of O RhD-negative RBCs. Materials and methods: The use of every O RhD-negative unit in Finland during a period of 1 month was reviewed. For each issued unit (n = 1105), unit age, urgency of transfusion, hospital and patient demographics, and specific reasons for issuing O RhD-negative units were recorded. Results: Almost half of the O RhD-negative units (n = 529, 47.9%) were issued to non-O RhD-negative patients. Only 22.3% (n = 118) were issued for females under the age of 50. Of the units for ABO-nonidentical transfusion, one-third (32.5%, n = 172) were issued for emergency transfusion, two-thirds (67.5%, n = 357) for non-urgent transfusions. The most common reason for issuing an O RhD-negative unit was inventory management (n = 172, 48.2% of units issued for non-urgent transfusion). Most of these units were issued close to the unit expiry date. Conclusion: This nationwide audit revealed that a significant proportion of O RhD-negative RBCs are used inappropriately. Clinicians should be educated on the appropriate use of O RhD-negative RBCs, and blood banks should develop strategies for inventory management to avoid issuing O RhD-negative units purely to prevent outdating. |
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| MeSH term(s) | Female ; Humans ; Erythrocyte Transfusion ; Erythrocytes ; Blood Banks ; Blood Transfusion ; Erythrocyte Count |
| Language | English |
| Publishing date | 2022-09-14 |
| Publishing country | England |
| Document type | Journal Article |
| ZDB-ID | 80313-3 |
| ISSN | 1423-0410 ; 0042-9007 |
| ISSN (online) | 1423-0410 |
| ISSN | 0042-9007 |
| DOI | 10.1111/vox.13357 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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